PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Racial disparities in receipt of guideline-concordant care in older adults with early breast cancer

JAMA Network Open

2024-10-24
(Press-News.org) About The Study: In this cohort study, non-Hispanic Black race was associated with increased odds of not receiving guideline-concordant care (GCC) and less timely treatment initiation. Non-Hispanic Black race was associated with increased all-cause mortality, which was reduced after adjusting for GCC and clinical and sociodemographic factors. These findings suggest that optimizing timely receipt of GCC may represent a modifiable pathway to improving inferior survival outcomes among older non-Hispanic Black patients with breast cancer.

Corresponding Author: To contact the corresponding author, Yehoda M. Martei, MD, MSCE, email yehoda.martei@pennmedicine.upenn.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2024.41056)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.41056?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102424

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

END


ELSE PRESS RELEASES FROM THIS DATE:

Fentanyl, heroin, methamphetamine, and cocaine analyte concentrations in urine drug testing specimens

2024-10-24
About The Study: This cross-sectional study found that absolute concentrations of fentanyl, methamphetamine, and cocaine in urine specimens increased from 2013 to 2023, with a decrease in heroin concentration during that period. The findings suggest that exposure to these substances, as well as the illicit drug supply, has fundamentally changed in many parts of the U.S., highlighting the need to reinforce surveillance initiatives and accelerate efforts to treat individuals with illicitly manufactured fentanyl and/or stimulant exposure.  Corresponding Author: To ...

UCLA researchers engineer experimental drug for preventing heart failure after heart attacks

UCLA researchers engineer experimental drug for preventing heart failure after heart attacks
2024-10-24
Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind experimental therapy that has the potential to enhance heart repair following a heart attack, preventing the onset of heart failure. Cardiovascular disease continues to be the world’s leading cause of death, contributing to one-third of deaths annually. After a heart attack, the heart’s innate ability to regenerate is limited, causing the muscle to develop scars to maintain its structural integrity. ...

Combining targeted therapy and immunotherapy improves overall survival in patients with anaplastic thyroid cancer

Combining targeted therapy and immunotherapy improves overall survival in patients with anaplastic thyroid cancer
2024-10-24
HOUSTON ― Researchers from The University of Texas MD Anderson Cancer Center demonstrated that anti-PD-L1 immunotherapy in combination with mutation-directed targeted therapy extended overall survival (OS) in patients with anaplastic thyroid carcinoma (ATC). Findings from the Phase II single center study published today in JAMA Oncology.  The trial enrolled 42 patients across three cohorts to evaluate mutation-matched targeted therapy and the immune checkpoint inhibitor atezolizumab. The median OS across all cohorts was 19 months, which compares favorably to historical OS of five months for patients with ATC. ...

Assessing the real climate costs of manufacturing

2024-10-24
Producing materials such as steel, plastics and cement in the United States alone inflicts $79 billion a year in climate-related damage around the world, according to a new study by engineers and economists at the University of California, Davis. Accounting for these costs in market prices could encourage progress toward climate-friendly alternatives.  “We wanted to look at the cost to society to produce these materials,” said Elisabeth Van Roijen, a recent Ph.D. graduate from the UC Davis Department of Civil and Environmental Engineering ...

A multi-functional simulation platform for on-demand ride service operations

A multi-functional simulation platform for on-demand ride service operations
2024-10-24
On-demand ride services or ride-sourcing services have been experiencing fast development and steadily reshaping the way people travel in the past decade. Various optimization algorithms, including reinforcement learning approaches, have been developed to help ride-sourcing platforms design better operational strategies to achieve higher efficiency. However, due to cost and reliability issues, it is commonly infeasible to validate these models and train/test these optimization algorithms within real-world ride-sourcing platforms. Acting as a proper test bed, a simulation platform for ride-sourcing systems will thus be essential for both ...

Research team undertakes review of carbon anodes for lithium-ion batteries

Research team undertakes review of carbon anodes for lithium-ion batteries
2024-10-24
A team of researchers has undertaken a study of the future of carbon anodes for lithium-ion batteries. Their review provides a comprehensive overview of the progression in carbon anode development and the current status of their industrialization. This study underscores the critical role of interphase regulation engineering in advancing lithium-ion battery technology.   Their research is published in the journal Carbon Future on September 24, 2024.   Today, graphite is the most commonly used material for anodes in lithium-ion batteries. Graphite can operate at a low voltage, is readily available, and cost effective. While graphite materials ...

Researchers improve speed and accuracy of 3D surface measurements

Researchers improve speed and accuracy of 3D surface measurements
2024-10-24
WASHINGTON — Researchers have developed a faster and more accurate method for acquiring and reconstructing high-quality 3D surface measurements. The approach could greatly improve the speed and accuracy of surface measurements used for industrial inspection, medical applications, robotic vision and more. “Traditional 3D imaging works by comparing two viewpoints, similar to how our eyes work together to judge depth,” said research team leader Ce Zhu from the University of Electronic Science and Technology of China. “In contrast, our new approach ‘feels’ the surface by projecting light ...

GPX4 promoter hypermethylation induced by ischemia/reperfusion injury regulates hepatocytic ferroptosis

2024-10-24
Background and Aims Glutathione peroxidase 4 (GPX4) is a key factor in ferroptosis, which is involved in ischemia-reperfusion injury. However, little is known about its role in hepatic ischemia-reperfusion injury (HIRI). This study aimed to investigate the role of GPX4 methylation in ferroptosis during HIRI.   Methods For the in vivo experiments, an ischemia-reperfusion model was created by subjecting mice to simulated HIRI. Ferroptosis occurrence, GPX4 promoter methylation, and global methylation levels were then assessed.   Results Ferroptosis ...

Advances in biointegrated wearable and implantable optoelectronic devices for cardiac healthcare

Advances in biointegrated wearable and implantable optoelectronic devices for cardiac healthcare
2024-10-24
A review paper by scientists at Institute of Chemistry, Chinese Academy of Sciences summarized the progress of biointegrated flexible and stretchable optoelectronics for wearable and implantable cardiac healthcare. The new review paper, published on Oct. 18 in the journal Cyborg and Bionic Systems, focuses on the advances in biointegrated flexible and stretchable optoelectronics for wearable and implantable cardiac healthcare systems. With the prevalence of cardiovascular disease, it is imperative that medical monitoring and treatment become more instantaneous and comfortable for ...

Science/Science Careers’ survey ranks top biotech, biopharma, and pharma employers

2024-10-24
The Science and Science Careers’ 2024 Top Employers Survey polled employees in biotechnology, biopharmaceutical, pharmaceutical, and related industries to determine the 20 best employers as well as their driving characteristics. Respondents to the web-based survey were asked to rate companies based on 24 characteristics, including innovative leadership, respect for employees, and social responsibility. Insmed, Bridgewater, New Jersey, receives the top honor this year in a ranking of the world’s most respected employers. The rankings, determined from a study conducted by an independent research firm commissioned by the Science/AAAS Office of Publishing, ...

LAST 30 PRESS RELEASES:

Wake Forest Institute for Regenerative Medicine (WFIRM) awarded up to $48 million to utilize body-on-a-chip technologies to study fibrosis-inducing chemical injuries

Study offers ‘compelling evidence’ for continuous stroke care improvement

Professor awarded NEH grant to advance anthropology research collections at Texas A&M

New tool helps scientists spot patterns in mountains of data

Glomerular filtration rate changes following UTI in children with vesicoureteral reflux

Dandelion-shaped supernova and zombie star

Experts call for clear and concise regulation of exosome-based treatments

Zebrahub: New atlas tracks zebrafish development like never before

Unnoticeable electric currents could reduce skin infections

Expanded newborn screening using genome sequencing for early actionable conditions

In pioneering study, gene technology outperforms standard newborn screening tests

Racial disparities in receipt of guideline-concordant care in older adults with early breast cancer

Fentanyl, heroin, methamphetamine, and cocaine analyte concentrations in urine drug testing specimens

UCLA researchers engineer experimental drug for preventing heart failure after heart attacks

Combining targeted therapy and immunotherapy improves overall survival in patients with anaplastic thyroid cancer

Assessing the real climate costs of manufacturing

A multi-functional simulation platform for on-demand ride service operations

Research team undertakes review of carbon anodes for lithium-ion batteries

Researchers improve speed and accuracy of 3D surface measurements

GPX4 promoter hypermethylation induced by ischemia/reperfusion injury regulates hepatocytic ferroptosis

Advances in biointegrated wearable and implantable optoelectronic devices for cardiac healthcare

Science/Science Careers’ survey ranks top biotech, biopharma, and pharma employers

Belief in growth is key to becoming the best

Study finds intense exercise may suppress appetite in healthy humans

New JNCCN study suggests Medicaid expansion improves cancer care and survival for people with aggressive type of breast cancer

Crustacean with panda-like coloring confirmed to be a new species

Need for psychology referrals increasing for children with food allergies

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel

Penicillin allergy delabeling in syphilis patients assists in furthering treatment

Burning incense can pose health risks for those with allergies and asthma

[Press-News.org] Racial disparities in receipt of guideline-concordant care in older adults with early breast cancer
JAMA Network Open