Trends in hospitalizations and liver transplants associated with alcohol-induced liver disease

JAMA

2024-11-14

(Press-News.org) About The Study: This study found significant rate increases for alcohol-induced liver disease-related hospitalizations and liver transplants across sex and age groups between 2005 and 2021. Although older males had the highest absolute increases, the greatest relative increases occurred in younger individuals, particularly females.

Corresponding Author: To contact the corresponding author, Michele Molinari, MD, MSc, email molinarim@upmc.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2024.21503)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.21503?guestAccessKey=4a087071-8c61-45b4-969b-687fa06537f0&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111424

END

ELSE PRESS RELEASES FROM THIS DATE:

Spinal cord stimulation vs medical management for chronic back and leg pain

2024-11-14

About The Study: This systematic review and network meta-analysis found that spinal cord stimulation therapies for treatment of chronic pain in back and/or lower extremities were associated with greater improvements in pain compared with conventional medical management. These findings highlight the potential of spinal cord stimulation therapies as an effective and valuable option in chronic pain management. Corresponding Author: To contact the corresponding author, Konstantinos Soulanis, M.Sc., email konstantinos.soulanis@iqvia.com. To access ...

Engineered receptors help the immune system home in on cancer

2024-11-14

Most cancer treatments – from chemotherapies to engineered immune cells – have a host of side effects, in large part because they affect healthy cells in the body at the same time as targeting tumor cells. For the same reason, designing new cancer drugs can be challenging due to the molecular similarities between tumor cells and healthy cells. Now, UC San Francisco researchers have designed highly customizable biological sensors which can ensure that engineered cells are only activated in certain environments – such as the vicinity of a tumor. This could yield cancer therapies ...

How conflicting memories of sex and starvation compete to drive behavior

2024-11-14

Two conflicting memories can both be activated in a worm’s brain, even if only one memory actively drives the animal’s behaviour, finds a new study by UCL researchers. In the paper published in Current Biology, the researchers showed how an animal’s sex drive can at times outweigh the need to eat when determining behaviour, as they investigated what happens when a worm smells an odour that has been linked to both good experiences (mating) and bad experiences (starvation). The scientists were seeking ...

Scientists discover ‘entirely unanticipated’ role of protein netrin1 in spinal cord development

2024-11-14

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have uncovered an unexpected role for the molecule netrin1 in organizing the developing spinal cord. The researchers discovered that netrin1, which is known primarily as a guidance cue that directs growing nerve fibers, also limits bone morphogenetic protein, or BMP, signaling to specific regions of the spinal cord. This boundary-setting function is critical because this signaling activity must be precisely confined to the dorsal region for sensory neurons to develop properly. Their findings, published in Cell ...

Novel SOURCE study examining development of early COPD in ages 30 to 55

2024-11-14

Miami (November 14, 2024) – Researchers are exploring how small airway abnormalities in younger smokers could help identify who is at risk of developing COPD and establish how the chronic lung disease progresses, according to a new article. The article is published in the September 2024 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open-access journal. Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease, comprising several conditions, including chronic bronchitis and emphysema, and can be caused ...

NRL completes development of robotics capable of servicing satellites, enabling resilience for the U.S. space infrastructure

2024-11-14

WASHINGTON – U.S. Naval Research Laboratory (NRL) Naval Center for Space Technology (NCST) in partnership with Defense Advanced Research Projects Agency (DARPA) successfully completed development of a spaceflight qualified robotics suite capable of servicing satellites in orbit, Oct. 8. Under DARPA funding, NRL developed the Robotic Servicing of Geosynchronous Satellites (RSGS) Integrated Robotic Payload (IRP). This transformative new space capability was delivered to DARPA’s commercial partner, Northrop Grumman’s SpaceLogistics, for ...

Clinical trial shows positive results for potential treatment to combat a challenging rare disease

2024-11-14

An international, phase 3 clinical trial led by investigators at Mass General Brigham could improve the treatment of a rare disease that can cause debilitating symptoms. The study, published in the New England Journal of Medicine, found that treatment with inebilizumab greatly reduced the symptoms of immunoglobulin G4–related disease (IgG4-RD), compared to placebo. “This is a huge day in the history of this disease,” said lead author John Stone, MD, MPH, a rheumatologist in the Division of Rheumatology, Allergy, and Immunology at Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system. “We are thrilled to have ...

New research shows relationship between heart shape and risk of cardiovascular disease

2024-11-14

A new multi-national study has revealed that the shape of the heart is influenced in part by genetics and may help predict the risk of cardiovascular diseases. Researchers from Queen Mary University of London, King’s College London, University of Zaragoza and University College London, as well as Complexo Hospitalario Universitario A Coruña are first to examine the genetic basis of the heart’s left and right ventricles using advanced 3D imaging and machine learning. Prior ...

Increase in crisis coverage, but not the number of crisis news events

2024-11-14

The world appears to be plagued by crises. “The financial crisis, the European debt crisis, the migration crisis, the COVID-19 pandemic, the war in Ukraine, the war in Gaza… The world seems to be stumbling from one existential crisis to the next, barely recovering from one before the next one hits,” said Stefan Geiß, a professor from the Department of Sociology and Political Science at the Norwegian University of Science and Technology (NTNU). However, are there really more crises now than before? Has it always been this way, or is something new happening? And if there are more public crises today ...

New study provides first evidence of African children with severe malaria experiencing partial resistance to world’s most powerful malaria drug

2024-11-14

NEW ORLEANS (November 14, 2024) — A new study from Uganda provides the first evidence to date that resistance to a lifesaving malaria drug may be emerging in the group of patients that accounts for most of the world’s malaria deaths: young African children suffering from serious infections. The study, presented today at the Annual Meeting of the American Society of Tropical Medicine and Hygiene and published in the Journal of the American Medical Association (JAMA), documented partial resistance to the malaria drug artemisinin in 11 of 100 children, ages 6 months to 12 years, who were being treated for ...

Weight-loss drug semaglutide reduces cocaine use in rats: Suggests possible first pharmacological treatment for human cocaine dependency

New meta-analysis demonstrates that access to the GeneSight test can significantly improve response and remission rates for patients with depression

Oral health treatment in patients due for surgery is associated with significantly lower rates of postoperative pneumonia and shorter hospital stays, per observational study in one Japanese hospital,

Oxygen came late to ocean depths during Paleozoic

Among women suffering hyperemesis (extreme nausea and vomiting) in pregnancy, half report considering terminating their pregnancy, and 9 in 10 have considered having no more children

Trends in hospitalizations and liver transplants associated with alcohol-induced liver disease

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: