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About The Article: Artificial intelligence carries promise and uncertainty for clinicians, patients, and health systems. This JAMA Summit Report presents expert perspectives on the opportunities, risks, and challenges of AI in health care, including how AI is developed, evaluated, regulated, and implemented across clinical and business domains.
This content is the result of JAMA Summit AI that was held in October 2024. Reflecting the multidisciplinary nature of JAMA Summit, this report features a diverse group of authors whose expertise spans clinical care, biomedical research, software engineering, data science, health policy, law, and industry innovation.
JAMA Summit is an initiative of JAMA and the JAMA Network that convenes leaders from across sectors and around the world to discuss and debate critical issues in medicine, health, and health care.
The JAMA Summit has two primary goals: first, to bring together thought leaders from diverse sectors to explore a key topic and identify actionable steps with immediate impact; and second, to spark broader conversations by publishing papers and multimedia content based on the themes that emerge from these discussions.
Author Contact Information: The Corresponding Author of the JAMA Summit Report is Derek C. Angus, M.D., M.P.H. Allison Hydzik, Senior Director of Public Relations at UPMC and University of Pittsburgh Health Sciences, can assist with scheduling interviews. Allison can be reached at 412-559-2431 and hydzikam@upmc.edu.
Contact the JAMA Media Relations department at mediarelations@jamanetwork.org to obtain contact information for additional authors.
About JAMA+ AI: For the latest research on AI from across the JAMA Network, visit the JAMA+ AI channel, which is celebrating its one-year anniversary this week. An email newsletter is available as well as a podcast.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2025.18490)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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University of California San Diego of Medicine researchers, in collaboration with the genetic testing company 23andMe, have identified regions of the human genome associated with cannabis use, uncovering new relationships with psychiatric, cognitive and physical health. The findings may inform the development of prevention and treatment strategies for cannabis use disorder. The study was published on October 13, 2025 in Molecular Psychiatry.
“Cannabis is widely used, but its long-term effects ...
About The Study: This analysis found that both low and high increases in social media use throughout early adolescence were significantly associated with lower performance in specific aspects of cognitive function, supporting a prior finding that greater screen time was negatively but weakly associated with adolescent cognitive performance.
Corresponding Author: To contact the corresponding author, Jason M. Nagata, MD, MSc, email jason.nagata@ucsf.edu.
To access the embargoed study: Visit our For The Media ...
A multi-center randomized controlled trial with critically ill adults aged 50 years and older admitted to intensive care units (ICUs) found that twice-daily slow-tempo music (60 to 80 beats per minute) did not shorten the duration of delirium or coma, or reduce delirium severity, pain or anxiety compared with a silence-track control.
While the trial did not mitigate delirium, it showed a trend to fewer days with delirium/coma among patients who received at least seven doses of slow-tempo music. There was also a trend toward fewer days of delirium/coma among patients ...
Sepsis, or infection causing life-threatening organ dysfunction, is a leading cause of death in children worldwide. In efforts to prevent this rare but critical condition, researchers developed and validated AI models that accurately identify children at high risk for sepsis within 48 hours, so that early preemptive care can be provided. These predictive models used routine electronic health record (EHR) data from the first four hours the child spent in the Emergency Department (ED), before organ dysfunction was present.
The multi-center study, led by Elizabeth Alpern, MD, MSCE, from Ann & Robert H. Lurie Children’s Hospital of Chicago, is the first to use ...
About The Study: In this comparative effectiveness study in veterans with diabetes, liraglutide, semaglutide, and dulaglutide initiators had similar risks for kidney and cardiovascular outcomes. Head-to-head randomized trials are needed to confirm these findings.
Corresponding Author: To contact the corresponding author, Srinivasan Beddhu, MD, email srinivasan.beddhu@hsc.utah.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2025.37297)
Editor’s Note: Please see the article for additional information, including other authors, author ...
About The Study: In this cohort study, exposure to antenatal corticosteroids (ACS) was associated with increased risks of infections in full-term children until age 21. In preterm children born before 34 weeks’ gestation, no association between ACS and infections was found. To minimize the adverse effects of ACS treatment, more stringent criteria for ACS administration and better prediction tools for preterm birth are required.
Corresponding Author: To contact the corresponding author, Rebecca M. Reynolds, ...
University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development - including the production of blood stem cells.
Human blood stem cells, also known as hematopoietic stem cells, are immature cells that can develop into any type of blood cell, including red blood cells that carry oxygen and various types of white blood cells crucial to the immune system.
The embryo-like structures, which the scientists have named ‘hematoids’, are self-organising and start producing blood after around ...
Near-death experiences can have lasting, life-changing effects, and new University of Virginia School of Medicine research sheds light on the types of counseling and support that can best help people cope.
The research, from UVA’s Division of Perceptual Studies, is believed to be the first to explore the most common and effective ways to assist people grappling with potentially profound changes to their world view. For most, near-death experiences, or NDEs, have a positive effect; the brush with ...
What began as a student project in 2023 will now serve a whole university community.
Illinois Chat, an official artificial intelligence (AI) software tool of the University of Illinois Urbana-Champaign, has launched for the Fall 2025 semester and is available for anyone on campus. In partnership with the Office of the Chief Information Officer (CIO) and Illinois Computes, NCSA developed Illinois Chat to offer large language model (LLM) abilities to the entire campus community.
This campus-developed tool allows users to create personalized LLM-based chatbots – ...
Florida Atlantic University has received a $3 million, five-year grant from the Substance Abuse and Mental Health Services Administration (SAMHSA), a division of the United States Department of Health and Human Services, to lead a transformative community initiative designed to prevent substance use among South Florida’s youth.
The new program, “Rising Strong: Empowering Youth for Substance-Free Futures,” will implement evidence-based, trauma-informed prevention strategies to reach more than 3,000 youth across Palm Beach and Broward counties ...
