(Press-News.org) Milan, Italy, 31 January 2010 – Most people who survive a stroke recover some degree of their motor, sensory and cognitive functions over the following months and years. This recovery is commonly believed to reflect a reorganisation of the central nervous system that occurs after brain damage. Now a new study, published in the February 2011 issue of Elsevier's Cortex, sheds further light on the recovery process through its effect on language skills.
For almost all right-handed people and for about 60% of left-handers, damage to the left side of the brain causes a condition known as aphasia, an acute or chronic impairment of language skills. The syndrome is strongly associated with damage to the left hemisphere of the brain; however, there is a long-standing controversy regarding the involvement of parts of the right hemisphere in language functions and their contribution to recovery from aphasia. The majority of experts stress the role of the dominant left side in language recovery, while others argue for a complementary (or compensatory) function of the right hemisphere.
Odelia Elkana, from the Hebrew University, Jerusalem, and colleagues investigated the systematic patterns of reorganisation in the brain's language functions, and their relation to linguistic performance, in patients recovering from childhood brain damage to the left hemisphere. They used functional MRI to detect patterns of brain activity while patients performed various linguistic tasks inside the scanner. The new study focused on a rare group of children whose brain damage had occurred after they had already developed language skills but while the brain was still developing, and therefore most able to reorganise its language functions.
According to the authors, the findings suggest that "recovery is a dynamic, ongoing process, may last for years after onset and is reflected in an increasing proficiency of inter-hemispheric coordination, rather than just in an increase of activation in one side or the other. Therefore, the role of each hemisphere in the recovery process is not only dependent on the stage of recovery (acute, sub-acute or chronic stage), but also within each of these stages it may continuously change over time."
###
Notes to Editors:
The article is "Cerebral reorganization as a function of linguistic recovery in children: An fMRI study" by Odelia Elkana, Ram Frost, Uri Kramer, Dafna Ben-Bashat, Talma Hendler, David Schmidt, and Avraham Schweiger, and appears in Cortex, Volume 47, Issue 2 (February 2010), published by Elsevier in Italy. Full text of the article featured above is available to members of the media upon request. Please contact the Elsevier press office, newsroom@elsevier.com. To schedule an interview, contact Dr Odelia Elkana, odelia.elkana@gmail.com.
About Cortex
Cortex is an international journal devoted to the study of cognition and of the relationship between the nervous system and mental processes, particularly as these are reflected in the behaviour of patients with acquired brain lesions, normal volunteers, children with typical and atypical development, and in the activation of brain regions and systems as recorded by functional neuroimaging techniques. It was founded in 1964 by Ennio De Renzi. The Editor in-chief of Cortex is Sergio Della Sala, Professor of Human Cognitive Neuroscience at the University of Edinburgh. Fax: 0131 6513230, e-mail: cortex@ed.ac.uk. Cortex is available online at http://www.sciencedirect.com/science/journal/00109452
About Elsevier
Elsevier is a world-leading publisher of scientific, technical and medical information products and services. The company works in partnership with the global science and health communities to publish more than 2,000 journals, including The Lancet and Cell, and close to 20,000 book titles, including major reference works from Mosby and Saunders. Elsevier's online solutions include SciVerse ScienceDirect, SciVerse Scopus, Reaxys, MD Consult and Nursing Consult, which enhance the productivity of science and health professionals, and the SciVal suite and MEDai's Pinpoint Review, which help research and health care institutions deliver better outcomes more cost-effectively.
A global business headquartered in Amsterdam, Elsevier employs 7,000 people worldwide. The company is part of Reed Elsevier Group PLC, a world-leading publisher and information provider, which is jointly owned by Reed Elsevier PLC and Reed Elsevier NV. The ticker symbols are REN (Euronext Amsterdam), REL (London Stock Exchange), RUK and ENL (New York Stock Exchange).
END
The endothelium is the inner lining of our blood vessels and normal functions of endothelial cells include enabling coagulation, platelet adhesion and immune function. Endothelial dysfunction is associated with reduced anticoagulant properties and the inability of arteries and arterioles to dilate fully.
The gradual decrease in endothelial function over time is a key factor in the development of diseases associated with ageing, especially cardiovascular disease (CVD). Many epidemiologic studies suggest protection against CVD from moderate intake of alcoholic beverages, ...
The recalled Sprint Fidelis implantable cardioverter-defibrillator (ICD) leads (Medtronic) failed more often in younger patients, women, and individuals with hereditary heart disease, according to a multicenter study published online Jan. 17 in Circulation. The researchers found that lead failure was not associated with death or serious injuries.
However, about half of the patients whose leads fractured experienced painful inappropriate shocks, according to lead author Robert G. Hauser, MD, of the Minneapolis Heart Institute® at Abbott Northwestern Hospital. In a previous ...
Cancer researchers have discovered an important protein, produced naturally inside cells, that appears to suppress the growth of prostate cancer cells in the laboratory. The findings, published tomorrow in the journal Cancer Research, offer promising leads for research towards new treatments.
Prostate cancer is the most common cancer among men in the UK, with 37,500 men diagnosed with the disease every year. Many prostate cancers are slow growing, but in some cases the cancer is aggressive and spreads to other parts of the body, such as the bone. These cases are much ...
Boys predominantly pass on flu to other boys and girls to girls, according to a new study of how swine flu spread in a primary school during the 2009 pandemic, published today in the journal Proceedings of the National Academy of Sciences. The results also suggest that flu transmission is most intensive between children of the same class, but that sitting next to an infected person does not significantly increase a child's risk of catching flu. The data will help researchers to model how epidemics spread and how interventions such as school closures can help contain an ...
New Haven, Conn.—Triceratops and Torosaurus have long been considered the kings of the horned dinosaurs. But a new discovery traces the giants' family tree further back in time, when a newly discovered species appears to have reigned long before its more well-known descendants, making it the earliest known member of its family.
The new species, called Titanoceratops after the Greek myth of the Titans, rivaled Triceratops in size, with an estimated weight of nearly 15,000 pounds and a massive eight-foot-long skull.
Titanoceratops, which lived in the American southwest ...
Scientists have discovered why orchids are one of the most successful groups of flowering plants - it is all down to their relationships with the bees that pollinate them and the fungi that nourish them. The study, published tomorrow in the American Naturalist, is the culmination of a ten-year research project in South Africa involving researchers from Imperial College London, the Royal Botanic Gardens, Kew, and other international institutions.
The orchid family is one of the largest groups of flowering plants, with over 22,000 species worldwide. Today's research suggests ...
Using funding provided under the American Reinvestment and Recovery Act, the U.S. Department of Energy's Savannah River National Laboratory has launched a demonstration project near one of the Savannah River Site's former production reactor sites to clean up chemically contaminated groundwater, naturally.
A portion of the subsurface at the Site's P Area has become contaminated with chlorinated volatile organic compounds that are essentially like dry-cleaning fluid. SRNL and Clemson University have patented a consortium of microbes that have an appetite for that kind ...
INDIANAPOLIS – A School of Science at Indiana University-Purdue University Indianapolis biophysicist has developed a new method to identify communication pathways connecting distant regions within proteins.
With this tool, Andrew J. Rader, Ph.D., assistant professor of physics, has identified a mechanism for cooperative behavior within an entire molecule, a finding that suggests that in the future it may be possible to design drugs that target anywhere along the length of a molecule's communication pathway rather than only in a single location as they do today. The discovery ...
CORVALLIS, Ore. – Genetic research is showing that healthy steelhead runs in Pacific Northwest streams can depend heavily on the productivity of their stay-at-home counterparts, rainbow trout.
Steelhead and rainbow trout look different, grow differently, and one heads off to sea while the other never leaves home. But the life histories and reproductive health of wild trout and steelhead are tightly linked and interdependent, more so than has been appreciated, a new Oregon State University study concludes.
The research could raise new challenges for fishery managers ...
Numerous nanomaterials are currently at the focus of public attention. In particular silver nanoparticles are being investigated in detail, both by scientists as well as by the regulatory authorities. The assumption behind this interest is that they are dealing with a completely new substance. However, Empa researchers Bernd Nowack and Harald Krug, together with Murray Heights of the company HeiQ have shown in a paper recently published in the journal Environmental Science & Technology that nanosilver is by no means the discovery of the 21st century. Silver particles with ...