NEW YORK, NY, October 25, 2012 (Press-News.org) A new study presented at the Annual Meeting of the American Society for Reproductive Medicine (ASRM) in San Diego, CA, offers further evidence that the fragile X mental retardation 1 gene (FMR1 gene) may play an important role in controlling women's fertility life cycles.
The study, conducted by researchers from the Center for Human Reproduction (CHR), a leading fertility center in New York City, and the Medical University of Vienna in Austria, compared the age of menarche (start of menstruation) and the number of CGG tri-nucleotide repeats on the FMR1 gene. Among the 222 women studied, a significant relationship was identified between the age of menarche and CGG counts. Specifically, women with at least one FMR1 allele with CGG counts higher than 34 were more likely to reach menarche after age 13 compared to women with CGG counts on both FMR1 alleles below 34.
The FMR1 gene has long been associated with neuro-psychiatric conditions, but only in recent years it has been shown to have controlling effects on women's ovarian function. While for neuro-psychiatric risks, the FMR1 gene is considered normal up to CGG repeats of 55, the CHR investigators defined CGG counts between 26 and 34 as normal (norm) in regards to ovarian function, with CGG counts higher than 34 being defined as high and those lower than 26 as low. In a number of prior publications, the same group demonstrated genotypes and sub-genotypes of the FMR1 gene to be statistically associated with different ovarian aging patterns and IVF pregnancy rates.
"This study revealed that women with at least one high FMR1 allele tend to start their reproductive life later than women with low or norm alleles," explains Norbert Gleicher, MD, Medical Director and Chief Scientists of CHR. "The finding further strengthens our hypothesis that the FMR1 gene has a significant influence on how a woman's ovaries reach maturity, and then decline with age, defining her reproductive life cycle over her lifetime."
Further studies are needed to better define how to predict a woman's reproductive potential as she moves through life, based on FMR1 genotypes and sub-genotypes. Currently, prediction of female reproductive potential is difficult, and often impossible. Utilization of FMR1 genotypes and sub-genotypes may potentially open up new opportunities.
About Center for Human Reproduction
The Center for Human Reproduction (CHR, http://www.centerforhumanreprod.com/), located in New York City, is one of the world's leading fertility centers. Because of its worldwide reputation as "fertility center of last resort," CHR has a worldwide patient following among women with DOR, whether due to advanced age, or due to premature ovarian aging (POA). Dr. Gleicher is available for further comments.
FMR1 Gene May Control Women's Fertility Life Cycle, According to Research
Research from a leading New York infertility center suggests that the FMR1 gene influences the age at which a woman reaches menarche.
2012-10-25
ELSE PRESS RELEASES FROM THIS DATE:
Ethos Consulting Group, Inc - Announces Opening in Denver, CO
2012-10-25
Through proven success with our client base, Ethos Consulting Group, Inc. has maintained long-standing relationships with major Fortune 500 companies in such industries as telecommunications, outsourced merchant services, retail, energy and utility services, and office products and supplies. Rather than be restricted by the limitations imposed through sales of specific products, Ethos Consulting Group, Inc.'s professionals concentrate their unique abilities in the delivery of direct services for these clients in what is commonly referred to as the B2B the "business-to-business", ...
Sterling Inc Launches New Practice Management Website For Optometric Practice Owners
2012-10-25
Sterling announced today the launch of its new website designed to assist optometric practice owners in managing their practices at http://www.SterlingOD.com. The new site offers management tips, optometrist success stories and a no-charge practice management seminar, available to practice owners by request, on DVD or online.
"Although optometrists are highly trained professionals," says Barbara Wilson, president of Sterling, "they are not necessarily taught how to manage a practice or staff. As a result, many optometrists want to take their practices ...
Famous Dave's Legendary Pit Bar-B-Que Smokes Competitors in National BBQ Competition
2012-10-25
Legendary Famous Dave's Pit Bar-B-Que participated in the 24th annual 'Best of the West Rib Nugget Cook Off' in Sparks, Nev. With over 50,000 passionate BBQ fans in attendance, Famous Dave's took home the "Best Sauce" award and placed in the top three for the "Best Ribs" award.
Famous Dave Anderson opened his first restaurant in 1995 and has won more than 600 awards, including top honors for Best Ribs, Best BBQ Sauce, Top Barbeque Restaurant Franchise, and countless others. Famous Dave's is known for its quality, home-style barbeque that's slow-cooked ...
CreAgri Inc. and Biominas Brasil to Introduce Award Winning Olivenol(R) plus to Latin America
2012-10-25
CreAgri, Inc., the world leader in the production of organic olive polyphenols, and Biominas Brasil, Brazil's leading accelerator for life science ventures, announced today that they have reached an exclusive agreement for the introduction of the award winning line of dietary supplements and skin care products Olivenol(R) plus to Brazil, Argentina and Chile.
"Latin American countries, and Brazil in particular, are fast growing markets for which CreAgri and Olivenol(R) have great expectations," affirmed Roberto Crea, Ph.D, inventor of Olivenol, Founder and CEO ...
It's Time to Get 'Gak'-ked!
2012-10-25
Gak is back! And Floam is in the home ... or at least it will be soon now that both products have hit Canadian store shelves. Distributed in Canada by RP Toys, Nickelodeon's Gak and Floam provide hours of squishing, stretching and modeling fun for children of all ages.
Anyone who remembers the '90s will remember the Gak attack. Now it's back, with even more bright colours and accessories. As soon as kids touch it, they develop a knack for Gak - rolling it, stretching it, bouncing it, blowing bubbles with it or even just squishing it to make wacky sounds.
Gak comes ...
Cass Community1 Social Services Launch & Dedication of New Permanent Supportive Housing for Detroit's Homeless
2012-10-25
Cass Community1 Social Services Launch & Dedication of New Permanent Supportive Housing for Detroit's Homeless Community Campus Provides Unique Support to City
What:
Dedication and official launch of $10 Million
Arthur Antisdel Apartments (Antisdel Apartments) project
Tours of Cass Community Social Services' (CCSS) Facilities
- Antisdel Apartments Expands CCSS' Community Campus to Four-Block Area
- 1st Homeless Housing Project with Geothermal heating/cooling system in Michigan
- 41 units of Permanent Supportive Housing
When:
Wednesday, October 24, 2012, ...
GammaTech to Showcase Durabook Rugged Computers and Tablets at AAPEX 2012
2012-10-25
GammaTech Computer Corp., a major international manufacturer and supplier of innovative notebook and tablet computers, will showcase its Durabook line of mobile rugged computers and tablets during the 2012 Automotive Aftermarket Products Expo (AAPEX) in booth 377. GammaTech will participate as part of the Automotive Aftermarket Industry Week from October 29 - November 1, 2012 in the Sands Expo Center in Las Vegas. GammaTech will exhibit the U12Ci, T7Q, RT10C and S15C to automotive industry leaders and innovators.
GammaTech products are sturdy, portable and rigorously ...
Lowe's and Millennium Lock Inc. to Cast Light on Black Friday With the Ultimate Lock.
2012-10-25
By making the Ultimate Lock more affordable, Lowe's and Millennium Lock seek to bring in markets and demographics never seen before creating massive potential for sales in 2012's fourth quarter. After getting its start in the Houston area Lowe's stores five years ago, the Ultimate Lock has seen expansion from 40 stores to nationwide, protecting thousands of families across the nation. Even with this kind of rapid expansion, Millennium Lock Inc and Lowe's Home Improvement have come together this Fall to bring the retail price down in the hopes that they can secure thousands ...
Storm Design Management & Consulting Looks to Centralize Client Pool by Making Indianapolis its Home.
2012-10-25
Known for his background as a professional designer from product development to retail environments, Mr. Spaulding also is sought after for his project management and ability to generate new business. After launching his small design boutique from his college dorm room at Purdue University, JSDC Inc. grew into one of Indiana's most successful product design firms landing projects with clients such as Ford Motor Co., Walmart, Apple, and Samsung, just to name a few. Ten years later JSDC was bought out by one of the largest consumer electronics companies in the world, utilizing ...
Time to Get Nautical: Martin County Nautical Flea Market and Seafood Festival
2012-10-25
The promoter Larry Burdgick states this event is the largest event of its type in Stuart, The Sailfish Capital of the World, and is situated in the middle of one of the biggest fishing and boating communities in the United States.
In today's economy, the Martin County Nautical Flea Market & Seafood Festival will provide an outlet for the marine industry and private individuals to sell overstocked, new and used marine equipment at a fraction of the original retail cost. Many boaters, fishermen and divers will find valuable items for their maritime lifestyle at bargain ...
LAST 30 PRESS RELEASES:
‘Molecular shield’ placed in the nose may soon treat common hay fever trigger
Beetles under climate stress lay larger male eggs: Wolbachia infection drives adaptive reproduction strategy in response to rising temperature and CO₂
Groundbreaking quantum study puts wave-particle duality to work
Weekly injection could be life changing for Parkinson’s patients
Toxic metals linked to impaired growth in infants in Guatemala
Being consistently physically active in adulthood linked to 30–40% lower risk of death
Nerve pain drug gabapentin linked to increased dementia, cognitive impairment risks
Children’s social care involvement common to nearly third of UK mums who died during perinatal period
‘Support, not judgement’: Study explores links between children’s social care involvement and maternal deaths
Ethnic minority and poorer children more likely to die in intensive care
Major progress in fertility preservation after treatment for cancer of the lymphatic system
Fewer complications after additional ultrasound in pregnant women who feel less fetal movement
Environmental impact of common pesticides seriously underestimated
The Milky Way could be teeming with more satellite galaxies than previously thought
New study reveals surprising reproductive secrets of a cricket-hunting parasitoid fly
Media Tip Sheet: Symposia at ESA2025
NSF CAREER Award will power UVA engineer’s research to improve drug purification
Tiny parasitoid flies show how early-life competition shapes adult success
New coating for glass promises energy-saving windows
Green spaces boost children’s cognitive skills and strengthen family well-being
Ancient trees dying faster than expected in Eastern Oregon
Study findings help hone precision of proven CVD risk tool
Most patients with advanced melanoma who received pre-surgical immunotherapy remain alive and disease free four years later
Introducing BioEmu: A generative AI Model that enables high-speed and accurate prediction of protein structural ensembles
Replacing mutated microglia with healthy microglia halts progression of genetic neurological disease in mice and humans
New research shows how tropical plants manage rival insect tenants by giving them separate ‘flats’
Condo-style living helps keep the peace inside these ant plants
Climate change action could dramatically limit rising UK heatwave deaths
Annual heat-related deaths projected to increase significantly due to climate and population change
Researchers discover new way cells protect themselves from damage
[Press-News.org] FMR1 Gene May Control Women's Fertility Life Cycle, According to ResearchResearch from a leading New York infertility center suggests that the FMR1 gene influences the age at which a woman reaches menarche.