Study establishes “ball and chain” mechanism inactivates key mammalian ion channel
A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a “ball-and-chain” channel-plugging mechanism, according to investigators at Weill Cornell Medicine. The findings boost the understanding of ion channel biology and could lead to new drugs that target these channels to treat disorders such as epilepsy and hypertension. Ion channels are protein structures embedded in cell membranes that allow charged molecules to flow into or out of the cell. They support essential biological functions, including signaling or communication between brain cells. The study, published ...
Read the release















