HOUSTON – (June 16, 2023) – Rice University chemist Anatoly Kolomeisky has won an award from the National Science Foundation to investigate how heterogeneity affects chemical and biological processes. The goal of his project is to develop analytical models that quantify the role of heterogeneity in various phenomena including catalytic reactions, antimicrobial peptides, early cancer development and lysis, a process describing cellular membrane breakdown. “We live in a world of heterogeneity,” ...

BOSTON – New research from Boston Medical Center found a significant correlation between biomarkers in the vitreous humor of the eye and pathologically confirmed cases of Alzheimer’s disease (AD) and Chronic Traumatic Encephalopathy (CTE) in post-mortem brain and eye tissue. Published in IOS Press, this exploratory study indicates that biomarkers in the vitreous humor may serve as a proxy for neuropathological disease. The incidence of dementias like AD continues to rise. As of 2021, 6.2 million North Americans above 65 years of age are suffering from AD, and this number is projected to reach 13.2 million by 2060. Diagnosis of both AD and CTE is based on symptoms, clinical exam ...

The Children’s Tumor Foundation (CTF) has announced that Brigid Garelik, MD, MPH, has been appointed Chief Medical Officer, overseeing the Foundation’s research and clinical initiatives. In this role, Dr. Garelik will set direction for the Foundation’s innovative R&D programs, developing effective clinical and preclinical strategies in order to deliver treatments to patients. She will also direct the Foundation’s educational programs in support of NF healthcare professionals, growing the NF field, and R&D related patient engagement. She will report to the President of the Children’s Tumor Foundation, Annette Bakker, PhD. Dr. Garelik is an accomplished ...

A new SGD 77 million research initiative has been launched today at the National University of Singapore (NUS) to boost innovation and research on advanced solar cell technologies in Singapore. Over the next five years, the REC@NUS Corporate R&D Laboratory for Next Generation Photovoltaics (REC@NUS Corp Lab), which is jointly set up by the Solar Energy Research Institute of Singapore (SERIS) at NUS and REC Solar (REC), will research, develop, and commercialise disruptive solar photovoltaic (PV) technologies based on perovskite-silicon tandem solar cells. Supported ...

A chemical linked to a higher risk of leukemia and other blood cell cancers creeps into millions of homes whenever residents light their gas stoves. A new Stanford-led analysis finds that a single gas cooktop burner on high or a gas oven set to 350 degrees Fahrenheit can raise indoor levels of the carcinogen benzene above those in secondhand tobacco smoke. Benzene also drifts throughout a home and lingers for hours in home air, according to the paper published June 22 in Environmental Science & ...

Leaf arrangements in the earliest plants differ from most modern plants, overturning a long-held theory regarding the origins of a famous mathematical pattern found in nature, research shows. The findings indicate that the arrangement of leaves into distinctive spirals, that are common in nature today, were not common in the most ancient land plants that first populated the earth’s surface. Instead, the ancient plants were found to have another type of spiral. This negates a long held theory about the evolution of plant leaf spirals, indicating that they evolved ...

About The Study: The results of this study suggest that Black veterans have lower rates of lung cancer screening that are not fully explained by demographic and socioeconomic variables, underscoring the need for further qualitative studies on barriers to lung cancer screening as well as evidence-based interventions targeted to Black veterans.  Authors: Neelima Navuluri, M.D., M.P.H., of the Duke University School of Medicine in Durham, North Carolina, is the corresponding author.  To access the embargoed study: ...

About The Study: The findings of this qualitative study suggest that institutional plans to protect frontline clinicians from the responsibility for allocating scarce resources may be unworkable, especially in a state of chronic crisis. Efforts are needed to directly integrate frontline clinicians into institutional emergency responses and support them in ways that reflect the complex and dynamic realities of health care resource limitation.  Authors: Catherine R. Butler, M.D., M.A., of the University of Washington in Seattle, ...

A new study by an international team from Africa, Asia and Europe has put forward three criteria for evaluating the success of migration as adaptation in the face of climate change: well-being, equity and sustainability. The study shows that while migration is increasingly recognised as an effective way to deal with climate risks, or a form of adaptation, it is far from a silver-bullet solution. For example, remittances – which include flows of money, ideas, skills and goods between migrants and their places of origin – are thought to be key to facilitating adaptation to climate change. But, drawing on evidence from every continent ...

A collaborative team led by researchers from City University of Hong Kong (CityU) recently invented an innovative method for synthesizing high-quality, semiconducting nanomesh at a lower temperature and production cost than conventional methods. The findings will help enable the large-scale production of nanomesh for next-generation electronics. Nanomesh is a nano-scale material formed from a network of nanowires. For several decades, one-dimensional materials like nanowires made of crystalline inorganic materials have been widely explored as the main driver for emerging electronics, as they have features like mechanical flexibility, ...

CHICAGO—A new Scientific Statement released today by the Endocrine Society highlights the differences between aspects of aging that are normal and sometimes over-treated, and those such as menopausal symptoms and osteoporosis that can be treated and deserve more attention. “Hormones and Aging: An Endocrine Society Scientific Statement,” reviews the current state of research on hormonal changes with age. The statement focuses on common endocrine-related changes in older people including menopause and the development ...

About The Study: In critically ill patients with sepsis, compared with intermittent administration, the continuous administration of the antibiotic meropenem did not improve the composite outcome of mortality and emergence of pandrug-resistant or extensively drug-resistant bacteria at day 28.  Authors: Giovanni Landoni, M.D., of the IRCCS San Raffaele Scientific Institute in Milan, Italy, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2023.10598) Editor’s ...

A new weevil species was discovered in Japan’s pristine subtropical forests on Ishigaki Island and Yanbaru National Park in Okinawa. Renowned for their remarkable biodiversity, the Ryukyu Islands are a chain of subtropical islands distributed between mainland Japan and Taiwan that boast a relatively isolated evolutionary history, and are home to a distinctive and fascinating insect fauna.   Researchers at the Okinawan Institute of Science and Technology (OIST) have been placing net traps to monitor insects on Okinawa ...

A human cell harbors roughly 2 meters of DNA, encompassing the essential genetic information of an individual. If one were to unwind and stretch out all the DNA contained within a single person, it would span a staggering distance – enough to reach the sun and back 60 times over. In order to manage such an astounding volume of biological information, the cell compacts its DNA into tightly packed chromosomes. “Imagine DNA as a piece of paper upon which all our genetic information is written.” Says Minke A.D. Nijenhuis, co-corresponding author. “The paper is folded into a very tight structure in order to fit all of that ...

Recently, Providencia spp. which have been detected in patients with gastroenteritis, and similar to enterohemorrhagic Escherichia coli. O157 and Salmonella spp., have been attracting attention as causative agents of food poisoning. For children with low immunity, food poisoning can be lethal as it causes severe symptoms such as diarrhea and dehydration, so clarifying the source of infection and pathogenic factors of Providencia spp., and establishing preventive methods are urgent issues worldwide. A joint research group led by Professor Shinji Yamasaki, Dr. Sharda Prasad Awasthi, a Specially Appointed Lecturer, and graduate ...

Staying up late at night has little impact on how long ‘night owls’ live, according to new research published in the peer-reviewed journal Chronobiology International. Data based on nearly 23,000 twins, however shows that evening types have a slightly increased risk of dying than morning types, but this is largely linked to smoking and drinking. The study which tracked people over the course of more than 37 years in Finland suggests that lifestyle should be considered. This is when analyzing the impact on health of chronotype – the body’s natural inclination to sleep at a certain time. “Our ...

A research team led by Dr. Minah Lee of the Energy Storage Research Center at the Korea Advanced Institute of Science and Technology(KIST) has developed a chemical activation strategy of magnesium metal that enables efficient operation of magnesium batteries in common electrolytes that are free of corrosive additives and can be mass-produced. While the demand for lithium-ion batteries is exploding due to the rapid growth of the electric vehicle and energy storage system(ESS) markets, the supply and demand of their raw materials such as lithium and cobalt ...

Fathers can make a huge difference in whether an infant is breastfed and placed to sleep safely, according to a recent survey of new fathers via the Pregnancy Risk Assessment Monitoring System (PRAMS) for Dads. This new tool is modeled on the annual surveillance system that the Centers for Disease Control and Prevention (CDC) and public health departments have used for more than 35 years to survey new mothers. By utilizing PRAMS for Dads, this article is the first to describe father-reported rates of infant breastfeeding and sleep practices in a state-representative sample. Findings are published in the journal Pediatrics. Among fathers who wanted their infant’s ...

Urine is one of the attractive sources for early and sensitive biomarker discovery since it can accumulate and reflect changes in the human body while being collected non-invasively. However, analysis of the urine proteome presents challenges due to its wide dynamic range, spanning approximately 10 orders of magnitude in protein concentrations. The presence of high-abundance proteins in urine can overshadow potential disease biomarkers, making their identification difficult. Fractionation and depletion ...

CHICAGO—Exposure to dioxins can negatively impact thyroid function, according to a study presented Thursday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill. Dioxins are highly toxic compounds that are primarily produced by industrial processes, and their persistence in the environment makes them a significant public health concern. They are produced through a variety of incineration processes, including improper municipal waste incineration and burning of trash. They can be released into the air during natural processes, such as forest fires and volcanoes. ...

Adverse cognitive effects linked to polychlorinated biphenyls (PCBs) exposure, a type of endocrine-disrupting chemical (EDC), have the potential to be passed down through generations, according to an animal study being presented Thursday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill. PCBs can mimic the effect of the hormone estrogen on the body, contributing to a variety of neuroendocrine, metabolic and reproductive problems. “Endocrine-disrupting chemicals present in our food, air, water and personal products may cause cognitive-behavioral disorders like attention-deficit/hyperactivity disorder or overeating in future generations,” ...

In two new reports, IIASA researchers, with support from colleagues at the Potsdam Institute for Climate Impact Research (PIK), examined the feasibility and fairness of emissions targets and considerations for the European Climate Law. Keywan Riahi, a member of the 15-strong EU Advisory Board and IIASA Energy, Climate, and Environment Program Director, took the lead in conducting the analyses. The European Scientific Advisory Board on Climate Change is an independent board entrusted with the crucial responsibility of providing transparent and scientific guidance to the EU on setting a new emissions reduction target to be achieved by 2040, as well as budgets for greenhouse ...

CRAG researchers have discovered that AtMC3 protein is exclusively located in a specific part of the plant vascular system. Increased levels of AtMC3 are able to confer enhanced tolerance to severe water scarcity conditions, without affecting plant yield. This knowledge will contribute to find tools to cope with increasing drought phenomena due to climate crisis.   Bellaterra (Barcelona), 16 June 2023   Researchers led by Núria Sánchez-Coll, CSIC researcher at the Centre ...

SUMMARY Treating a mouse model of multiple sclerosis with the pregnancy hormone estriol reversed the breakdown of myelin in the brain’s cortex, a key region affected in multiple sclerosis, according to a new UCLA Health study. BACKGROUND In multiple sclerosis, inflammation spurs the immune system to strip away the protective myelin coating around nerve fibers in the brain’s cortex, hampering electrical signals sent and received by the brain. Atrophy of the cortex in MS patients is associated with permanent worsening of disability, such as cognitive decline, visual impairment, weakness and sensory loss. No currently available treatments ...

INDIANAPOLIS — Researchers at the School of Science at IUPUI will lead two grants totaling $11.7 million from the U.S. Department of Defense to fund research on discovering a drug treatment for hydrocephalus, a condition commonly associated with complications from traumatic brain injury that causes cerebrospinal fluid to accumulate in the brain. Using funds from a $7.8 million Department of Defense Focused Program grant, Bonnie Blazer-Yost and Teri Belecky-Adams, both professors in the Department of Biology, will team up with scientists from Johns Hopkins University to test the effectiveness of treatments for three types of hydrocephalus — genetic, ...