First direct visualization of a zero-field pair density wave
2023-07-03
UPTON, NY—In the field of superconductivity—the phenomenon in which electrons can flow through a material with essentially zero resistance—the “holy grail” of discovery is a superconductor that can perform under everyday temperatures and pressures. Such a material could revolutionize modern life. But currently, even the “high-temperature” (high-Tc) superconductors that have been discovered must be kept very cold to function—too cold for most applications.
Scientists still have much to learn before room-temperature ...
Polyphenols Applications 2023 paves the way for artificial intelligence-enhanced therapeutics and space food
2023-07-03
Artificial Intelligence, Space Food & Polyphenols: 2 Ambitious Projects
Polyphenols Applications 2023 World Congress, which will be held on September 28-29 in Malta, will support 2 projects in order to advance in the polyphenols innovations:
1- Polyphenols & Artificial Intelligence:
This project aims to leverage artificial intelligence techniques to enhance the understanding and utilization of polyphenols. You will utilize machine-learning algorithms to analyze large datasets on polyphenols, including their chemical structures, bioactivities, and health effects. ...
Supportive communities can help increase breastfeeding rates for moms, MU study finds
2023-07-03
COLUMBIA, Mo. -- While formula-feeding babies is a safe and convenient option, research studies have shown natural breastfeeding is linked to numerous health benefits for both mother and child. For mothers, breastfeeding can improve recovery after giving birth and lower the risks of cancer. For babies, the nutrients strengthen their immune system and help lower their risk of developing obesity and diabetes.
Now, a new study at the University of Missouri Sinclair School of Nursing is helping researchers better understand the factors that influence moms, particularly in rural areas where breastfeeding is less common, when deciding how to feed their babies.
In the study, ...
Dementia is not the end of learning
2023-07-03
People with dementia still have the ability to learn new things despite their illness. This is the conclusion of a doctoral thesis recently presented at Linköping University, Sweden. Its findings debunk the general belief that people with dementia are empty shells, according to Elias Ingebrand, who conducted the study.
Elias Ingebrand let ten dementia sufferers, eight of whom lived in care facilities, try using computer tablets for the first time in their lives. A staff member or a loved one was there for support, but the only instruction given to participants ...
New study reveals abrupt shift in tropical Pacific climate during Little Ice Age
2023-07-03
Summary
An El Niño event has officially begun. The climate phenomenon, which originates in the tropical Pacific and occurs in intervals of a few years will shape weather across the planet for the next year or more and give rise to various climatic extremes. El Niño-like conditions can also occur on longer time scales of decades or centuries. This has been shown to have occurred in the recent past by an international research team led by Ana Prohaska of the University of Copenhagen and Dirk Sachse of the German Research Centre for Geosciences (GFZ). Their analysis of biomarkers – organic molecules or molecular fossils from vascular plants – in ...
Kabbani to receive funding for study of mitochondrial targeting and regulation
2023-07-03
Nadine Kabbani, Associate Professor, School of Systems Biology, is set to receive $100,000 from Charles Morgan for: "Mitochondrial Targeting and Regulation." This funding will begin in July 2023 and will end in July 2025.
Regarding the importance of the project, Kabbani said, "Studies suggest an important role for mitochondrial regulation in many human diseases. The targeting of mitochondrial processes has thus emerged as an important strategy in drug design and biomarker discovery. In addition, mitochondrial responses are especially useful in toxicity testing for medical and environmental applications. The goal of this project is to identify mitochondrial ...
Base editing shows potential superiority for curing sickle cell disease
2023-07-03
(MEMPHIS, Tenn. – July 03, 2023) Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia. These two common life-threatening anemias afflict millions of individuals across the globe. Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard used a next-generation genome editing technology, adenosine base editing, to restart fetal hemoglobin expression in SCD patient cells. The approach raised the expression of fetal hemoglobin to higher, more stable, and more uniform levels than other genome editing technologies that use ...
EMBARGOED Sylvester Research: Remnants of ancient retrovirus may drive aggressiveness and resilience of malignant brain cancers
2023-07-03
MIAMI, FLORIDA (EMBARGOED UNTIL JULY 3, 2023 AT NOON ET) – The median length of survival after diagnosis of glioblastoma is 14 months, but some of these brain tumors are more aggressive and resistant to treatment than others, and a new study from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests reactivation of an ancient retrovirus may be at least partly to blame.
“Our lab found that an evolutionary dormant retrovirus from 6 million years ago – HML-2, a subtype of HERV-K– contributes to brain tumor formation. We demonstrated for the first time that this virus, when reactivated, ...
Quasar ‘clocks’ show Universe was five times slower soon after the Big Bang
2023-07-03
Scientists have for the first time observed the early universe running in extreme slow motion, unlocking one of the mysteries of Einstein’s expanding universe.
Einstein’s general theory of relativity means that we should observe the distant – and hence ancient – universe running much slower than the present day. However, peering back that far in time has proven elusive. Scientists have now cracked that mystery by using quasars as ‘clocks'.
“Looking back to a time when the universe was ...
Maternal mortality in the U.S. more than doubled between 1999 and 2019
2023-07-03
IHME/Mass General Brigham study finds rates highest for Black population; largest increase seen in American Indian and Alaskan Native populations
High rates of maternal mortality found in northern Mountain states and the Midwest in addition to the South, a region traditionally known to have high rates
Study is the first such analysis for every state, showing differences in each by racial and ethnic groups
A new study by investigators from the Institute for Health Metrics and Evaluation (IHME) at the University of ...
New brain circuit for epilepsy uncovered
2023-07-03
Brigham researchers mapped lesions related to epilepsy to a common brain circuit
This study points to a novel role of deep brain circuits in the cause and control of epilepsy
New findings highlight the possibility of using this brain circuit to guide brain stimulation treatments for epilepsy
Focal epilepsy affects over 30 million patients worldwide and is commonly caused by brain lesions, such as stroke. However, it is unclear why some lesion locations cause epilepsy while others do not. A new study by investigators from the Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, found ...
Associations of food insecurity and memory function among middle to older–age adults
2023-07-03
About The Study: Food insecurity was associated with slightly faster memory decline among middle to older–age individuals, suggesting possible long-term negative cognitive function outcomes associated with exposure to food insecurity in older age.
Authors: Adina Zeki Al Hazzouri, Ph.D., of Columbia University in New York, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2023.21474)
Editor’s ...
Trends in state-level maternal mortality by racial and ethnic group
2023-07-03
About The Study: While maternal mortality remains unacceptably high among all racial and ethnic groups in the U.S., American Indian and Alaska Native and Black individuals are at increased risk, particularly in several states where these inequities had not been previously highlighted. Maternal mortality persists as a source of worsening disparities in many U.S. states and prevention efforts during this study period (1999 to 2019) appear to have had a limited impact in addressing this health crisis.
Authors: Gregory A. ...
Global, regional, and national epidemiology of diabetes in children
2023-07-03
About The Study: Childhood diabetes is an increasing global health challenge with rising incidence. Results of this study suggest that despite the global decline in deaths and disability-adjusted life-years (DALYs), the number of deaths and DALYs remains high among children with diabetes, especially in low Sociodemographic Index regions. Improved understanding of the epidemiology of diabetes in children may facilitate prevention and control.
Authors: Xiaodong Sun, M.D., Ph.D., and Ningning Hou, M.D., of the Affiliated Hospital of Weifang Medical ...
Trends in mortality from poisonings, firearms, and all other injuries by intent
2023-07-03
About The Study: The results of this study suggest that from 1999 to 2020, death rates due to poisonings, firearms, and all other injuries increased substantially in the U.S. The rapid increase in deaths due to unintentional poisonings and firearm homicides is a national emergency that requires urgent public health interventions at the local and national levels.
Authors: Wayne R. Lawrence, Dr.P.H., of the National Institutes of Health in Bethesda, Maryland, is the corresponding author.
To ...
Preventing stroke disability in a community with high rate of poverty
2023-07-03
· Use of successful medications to break up blood clots rose from 4% to 14% due to new approach
Suspected stroke victims now bypass emergency room for CT scanner and nurse stroke experts, who support patient care team
Community educators went to beauty and barber shops, churches and water distribution centers to deliver stroke-awareness talks
Approach can be duplicated by other communities to improve treatment
CHICAGO --- The use of thrombolysis, medications to break up blood clots, for acute ischemic stroke reduces post-stroke disability, but it is underutilized. This particularly affects Black individuals, who experience ...
Everything in balance? How a molecular switch controls lipid metabolism
2023-07-03
Our body’s fat metabolism plays a vital role in energy production in our body. A research team at the University of Basel, Switzerland, has discovered a molecular switch that regulates lipid metabolism in our cells. This switch controls the storage or conversion of lipids into energy.
All organisms need energy to live. We get energy from various components of our food. Our body uses a part of this energy directly and stores the rest. While glucose serves as an immediately available energy source, fats are stored as energy reserve in form of lipid droplets within our cells.
When the body needs energy from these fat stores, lipids are transported ...
AI and CRISPR precisely control gene expression
2023-07-03
Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.
The study by researchers at New York University, Columbia Engineering, and the New York Genome Center, combines a deep learning model with CRISPR screens to control the expression of human genes in different ways—such as flicking a light switch to shut them off completely or by using a dimmer knob to partially turn down their activity. These precise gene controls could be used to develop new CRISPR-based therapies.
CRISPR is a gene ...
Older frail patients have a 1-in-3 chance of surviving CPR during surgery
2023-07-03
It’s estimated that around 25% of patients who have a cardiac arrest and receive cardiopulmonary resuscitation (CPR) in a normal hospital setting will survive. Those odds shoot up to 50% for patients who receive CPR during or in the immediate period following surgery, where they are closely monitored by specialists who know their medical history and can intervene without delay. But it’s unclear whether that trend applies to frail patients, who are often older and at a higher risk of experiencing CPR-related trauma and complications. Such uncertainty has led some doctors ...
Transplantation of genome-edited iPS cells delivers therapeutic molecules in vivo
2023-07-03
Induced pluripotent stem (iPS) cells have a great impact on biology and medicine, and they are expected to improve regenerative medicine. Since 2014 when a sheet of retinal pigment epithelial cells derived from iPS cells was transplanted into patients with age-related macular degeneration, clinical trials have been conducted with various cell types derived from iPS cells. While iPS cells derived from healthy individuals have been used so far, it is expected that transplantation therapy using iPS cells can be enhanced through genetic modification in the future.
Therefore, we addressed this possibility by utilizing a Fabry disease mouse model, ...
A spatiotemporal intelligent framework and experimental platform for urban digital twins
2023-07-03
Research Background
The era of Big Data features intelligence, ubiquity, and interconnection of all things. It comes with other advanced information technologies, such as the Internet, Cloud Computing (CC), Internet of Things (IoT), and Artificial Intelligence (AI) . Human society has also gradually entered the Ternary Space from the Binary Space. That is, from the Social Space (the sum of human behavior and social activities) to the Information Space (the computer, Internet, and data information built on physical space and social space) . The Ternary Space maps and digitally connect the urban physical and social ...
Sheep and cattle-killing disease carriers never take a break
2023-07-03
Bluetongue virus, an incurable cattle and sheep-killing disease, is spread by tiny flies once thought to disappear in winter. New research demonstrates that though they are harder to find when it’s cold, they remain active.
Bluetongue virus is common in cattle throughout most of the United States, particularly in the southwestern U.S. with nearly 20% of some California cattle herds infected. Due to concerns about spread of this virus, exports of U.S. cattle and cattle products to parts of Europe and Asia have been restricted to prevent contamination.
However, not all infected animals die. The main symptoms are elevated temperatures, lethargy, ...
2023 EPS Europhysics Prize
2023-07-03
Prof. Claudia Felser is a director at the Max Planck Institute for Chemical Physics of Solids in Germany, Prof. B. Andrei Bernevig is a Professor of Physics at Princeton University in the United States and Visiting Ikerbasque Professor at Donostia International Physics Center in Spain.
The Prize will be presented on Wednesday 6th September 2023, during the Awards Session of the 30th General Conference of the EPS Condensed Matter Division (CMD30), to be held in Milan (joint organization with FisMat in Italy). This prize has been awarded since 1975 (this is the 40th edition) and is one ...
A UCLA-led team has received a $925,000 CDC grant to track mpox outbreaks across the US
2023-07-03
The effort is led by Dr. David Talan, a professor of emergency medicine and infectious diseases in the UCLA Department of Emergency Medicine at the David Geffen School of Medicine at UCLA.
Summer 2022 saw an outbreak of the disease that infected people in several countries across the globe. That outbreak receded by the following fall after widespread public attention and vaccination of high-risk individuals, prompting the World Health Organization on May 11, 2023 to declare an end to mpox as a global health emergency.
But a recent outbreak among 20 people in Chicago, including some vaccine breakthrough ...
Endocrine Society’s Journal of the Endocrine Society earns first Impact Factor
2023-07-03
WASHINGTON—The Endocrine Society’s Journal of the Endocrine Society (JES) received its first Impact Factor score in 2022, while the Society’s other journals maintained high rankings on the prestigious measure of scholarly publishing.
The 2022 Impact Factors were released June 28 by Journal Citation Reports, an annual publication of Clarivate Analytics.
JES, which launched in 2017, is an open access journal providing rapid publication of clinical research, clinical practice information, and basic research in all areas of endocrinology. The publication also ...
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