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More intense predation in the tropics can limit marine invasions

2021-06-25
Night and day, oil tankers, yachts and cargo ships stacked with shipping containers ply the 80-kilometer (50-mile) waterway through the jungles of Panama between the Atlantic and the Pacific Ocean: about 40 ships every 24 hours. But even though the Canal is fed by freshwater rivers that empty through the locks on each end, a system that generally prevents fish and smaller marine invertebrates from hopping from ocean to ocean, some still manage to get through, clinging to the hulls of ships. Other invading species arrive from far-flung ports, dumped with ballast water as ships prepare for transit. "Panama is a major shipping hub that provides amazing opportunities to test key ideas about marine invasions by studying ...

Inflatable, shape-changing spinal implants could help treat severe pain

2021-06-25
A team of engineers and clinicians has developed an ultra-thin, inflatable device that can be used to treat the most severe forms of pain without the need for invasive surgery. The device, developed by researchers at the University of Cambridge, uses a combination of soft robotic fabrication techniques, ultra-thin electronics and microfluidics. The device is so thin - about the width of a human hair - that it can be rolled up into a tiny cylinder, inserted into a needle, and implanted into the epidural space of the spinal column, the same area ...

Nanotech OLED electrode liberates 20% more light, could slash display power consumption

2021-06-25
A new electrode that could free up 20% more light from organic light-emitting diodes has been developed at the University of Michigan. It could help extend the battery life of smartphones and laptops, or make next-gen televisions and displays much more energy efficient. The approach prevents light from being trapped in the light-emitting part of an OLED, enabling OLEDs to maintain brightness while using less power. In addition, the electrode is easy to fit into existing processes for making OLED displays and light fixtures. "With our approach, you can do it all in ...

Researchers give yeast a boost to make biofuels from discarded plant matter

Researchers give yeast a boost to make biofuels from discarded plant matter
2021-06-25
More corn is grown in the United States than any other crop, but we only use a small part of the plant for food and fuel production; once people have harvested the kernels, the inedible leaves, stalks and cobs are left over. If this plant matter, called corn stover, could be efficiently fermented into ethanol the way corn kernels are, stover could be a large-scale, renewable source of fuel. "Stover is produced in huge amounts, on the scale of petroleum," said Whitehead Institute Member and Massachusetts Institute of Technology (MIT) biology professor Gerald Fink. "But there are enormous technical challenges to using them cheaply to create biofuels and other important chemicals." And so, year after year, most of the woody corn material is left in the fields to rot. Now, a ...

Test distinguishes SARS-CoV-2 from other coronaviruses with 100% accuracy

Test distinguishes SARS-CoV-2 from other coronaviruses with 100% accuracy
2021-06-25
DURHAM, N.C. - Biomedical engineers at Duke University have demonstrated a tablet-sized device that can reliably detect multiple COVID-19 antibodies and biomarkers simultaneously. Initial results show the test can distinguish between antibodies produced in response to SARS-CoV-2 and four other coronaviruses with 100% accuracy. The researchers are now working to see if the easy-to-use, energy-independent, point-of-care device can be used to predict the severity of a COVID-19 infection or a person's immunity against variants of the virus. Having also recently shown the same "D4 assay" platform can detect Ebola infections a day earlier than the gold standard polymerase chain reaction (PCR) test, the researchers say the results show how flexible the technology can be to adapt to other ...

Engineered yeast could expand biofuels' reach

2021-06-25
CAMBRIDGE, MA - Boosting production of biofuels such as ethanol could be an important step toward reducing global consumption of fossil fuels. However, ethanol production is limited in large part by its reliance on corn, which isn't grown in large enough quantities to make up a significant portion of U.S. fuel needs. To try to expand biofuels' potential impact, a team of MIT engineers has now found a way to expand the use of a wider range of nonfood feedstocks to produce such fuels. At the moment, feedstocks such as straw and woody plants are difficult to use for biofuel production because they first need to be broken down to fermentable sugars, a process that releases numerous byproducts that are toxic to yeast, the microbes most commonly used to produce biofuels. The ...

Structural biology reveals new opportunities to combat tuberculosis

Structural biology reveals new opportunities to combat tuberculosis
2021-06-25
Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world's population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a major threat to global health security, and has been declared by the World Health Organization as a global health emergency. Reduced access to diagnosis and treatment during the COVID-19 pandemic is expected to dramatically increase the number of tuberculosis infections. This will set global efforts to tackle the disease back several years. Tuberculosis is caused by infection with Mycobacterium tuberculosis: a bacterium that infects human lungs and other organs by using complex molecular ...

Texan voters unsure if state can tackle power grid issues

2021-06-25
When Winter Storm Uri hit, many Texans lost power from February 14-20, resulting in losses of lives and economic activity, and damages to their homes that for some are still not completely repaired. Now, four months later as demand for electricity has increased at the start of the summer amid tight supply, Texans continue to prioritize improvements to the power grid, albeit with doubt as to whether the Texas Legislature and Governor can get the job done. In a survey by the Hobby School of Public Affairs and UH Energy at the University of Houston fielded between May 13-24, 1,500 individuals in Texas aged 18 and older responded to a series of questions regarding their experience during Winter Storm Uri and their evaluation ...

Further hope for BCG vaccine in stemming type 1 diabetes

2021-06-25
BOSTON - At the recent 2021 Annual Scientific Sessions of the American Diabetes Association, researchers from Massachusetts General Hospital (MGH) presented positive updates on their trials of the bacillus Calmette-Guérin (BCG) vaccine to safely and significantly lower blood sugars. In type 1 diabetes, an autoimmune disease which currently has no cure, T cells attack the pancreas and destroy its ability to create insulin, a hormone vital in allowing glucose to enter cells to produce energy. In prior work, Denise Faustman, MD, PhD, director ...

Study confirms the low likelihood that SARS-CoV-2 on hospital surfaces is infectious

2021-06-25
A new study by UC Davis researchers confirms the low likelihood that SARS-CoV-2 contamination on hospital surfaces is infectious. END ...

Scientists use NASA satellite data to track ocean microplastics from space

Scientists use NASA satellite data to track ocean microplastics from space
2021-06-25
Scientists from the University of Michigan have developed an innovative way to use NASA satellite data to track the movement of tiny pieces of plastic in the ocean. Microplastics form when plastic trash in the ocean breaks down from the sun's rays and the motion of ocean waves. These small flecks of plastic are harmful to marine organisms and ecosystems. Microplastics can be carried hundreds or thousands of miles away from the source by ocean currents, making it difficult to track and remove them. Currently, the main source of information about the location ...

Controversies and consensus in thyroid cancer care

Controversies and consensus in thyroid cancer care
2021-06-25
New Rochelle, NY, June 24, 2021—The American Thyroid Association, the European Association of Nuclear Medicine, the European Thyroid Association, and the Society of Nuclear Medicine and Molecular Imaging released a joint statement on three key topics addressing controversies in thyroid cancer care. The joint statement is published in the peer-reviewed journal Thyroid®, the official journal of the American Thyroid Association® (ATA®).Click here to read the statement now. An inter-societal working group addressed the current controversies and evolving concepts in three main areas: peri-operative risk stratification; the role of diagnostic radioactive iodine ...

Performance-enhancing substance use: A link to criminal offending

2021-06-25
Toronto, ON - Despite research showing associations between anabolic steroid use and criminal offending, the possibility of a similar association between legal performance-enhancing substance use, such as creatine, and criminal offending remained unknown. A new study published online in the journal Drug and Alcohol Dependence now shows that both forms of performance-enhancing substance use is longitudinally associated with criminal offending among U.S. adults. The study, which analyzed a sample of over 9,000 U.S. participants from the National Longitudinal Study ...

Makowski, Pierre publish findings on obesity and response to cancer therapy

Makowski, Pierre publish findings on obesity and response to cancer therapy
2021-06-25
Liza Makowski, PhD, professor in the Department of Medicine and the UTHSC Center for Cancer Research, has long been interested in how the immune system is altered by obesity and how this impacts cancer risk and treatment. "Obesity is complex, because it can cause both inflammation and activate counter-inflammation pathways leading to immunosuppression," Dr. Makowski said. "How obesity impacts cancer treatments is understudied." Obese patients with breast cancer often have worse outcomes than non-obese patients. However, exciting developments are being made in other cancers that may also hold promise for treating breast cancer. In studies of ...

Smart transfer rules can strengthen EU climate policy

2021-06-25
"Fit for 55": under this heading, the EU Commission will specify the implementation of the European Green Deal on 14 July. This refers to the more ambitious climate policy announced, with 55 instead of 40 percent emission reduction by 2030 (relative to 1990), and net-zero emissions in 2050. Coordination between the 27 EU states is expected to be difficult since unanimity is usually required here for sweeping changes. An economic model study by the Berlin-based climate research institute MCC (Mercator Research Institute on Global Commons and Climate Change) and the Potsdam Institute for Climate Impact Research (PIK) examines how to achieve good results under such conditions. The study has just been published in the renowned Journal of Environmental ...

Study finds structural changes in the SARS-CoV-2 Alpha and Beta variants

Study finds structural changes in the SARS-CoV-2 Alpha and Beta variants
2021-06-25
New SARS-CoV-2 variants are spreading rapidly, and there are fears that current COVID-19 vaccines won't protect against them. The latest in a series of structural studies of the SARS-CoV-2 variants' "spike" protein, led by Bing Chen, PhD, at Boston Children's Hospital, reveals new properties of the Alpha (formerly U.K.) and Beta (formerly South Africa) variants. Of note, it suggests that current vaccines may be less effective against the Beta variant. Spike proteins, on the surface of SARS CoV-2, are what enable the virus to attach to and enter our cells, and all current vaccines are directed against them. The new study, published in Science on June 24, used cryo-electron microscopy (cryo-EM) ...

Hard-working enzyme keeps immune cells in line

Hard-working enzyme keeps immune cells in line
2021-06-25
LA JOLLA, CA--Researchers at La Jolla Institute for Immunology (LJI) have shed light on a process in immune cells that may explain why some people develop cardiovascular diseases. Their research, published recently in Genome Biology, shows the key role that TET enzymes play in keeping immune cells on a healthy track as they mature. The scientists found that other enzymes do play a role in this process--but TET enzymes do the heavy lifting. "If we can figure out what's going on with these enzymes, that could be important for controlling cardiovascular disease," ...

One "Ring" to rule them all: curious interlocked molecules show dual response

One Ring to rule them all: curious interlocked molecules show dual response
2021-06-25
Scientists at Tokyo Institute of Technology design polymers infused with a stress-sensitive molecular unit that respond to external forces by switching on their fluorescence. The researchers demonstrate the fluorescence to be dependent on the magnitude of force and show that it is possible to detect both, reversible and irreversible polymer deformations, opening the door to the exploration of new force regimes in polymers. Besides causing physical motion, mechanical forces can drive chemical changes in controlled and productive ways, allowing for desirable material properties. One way to go about this is by introducing a so-called mechanophore ...

Just mix it up: New synthetic method for making amphiphilic molecules without additives

Just mix it up: New synthetic method for making amphiphilic molecules without additives
2021-06-25
Amphiphilic molecules, which aggregate and encapsulate molecules in water, find use in several fields of chemistry. The simple, additive-free connection of hydrophilic and hydrophobic molecules would be an efficient method for amphiphilic molecule synthesis. However, such connections, or bonds, are often fragile in water. Now, scientists at Tokyo Institute of Technology have developed an easy way to prepare water-stable amphiphiles by simple mixing. Their new catalyst- and reagent-free method will help create further functional materials. Soaps and detergents are used to clean things like clothes and dishes. But how do they actually work? It turns out that they are made of long molecules ...

How brain cells compensate for damage from a stroke

2021-06-25
A study from UCLA neurologists challenges the idea that the brain recruits existing neurons to take over for those that are lost from stroke. It shows that in mice, undamaged neurons do not change their function after a stroke to compensate for damaged ones. A stroke occurs when the blood supply to a certain part of the brain is interrupted, such as by a blood clot. Brain cells in that area become damaged and can no longer function. A person who is having a stroke may temporarily lose the ability to speak, walk, or move their arms. Few patients recover fully and most are left with some disability, but the majority exhibit some degree of spontaneous recovery during the first few weeks after the stroke. Doctors and scientists don't fully ...

'Dragon man' fossil may replace Neanderthals as our closest relative

2021-06-25
A near-perfectly preserved ancient human fossil known as the Harbin cranium sits in the Geoscience Museum in Hebei GEO University. The largest of known Homo skulls, scientists now say this skull represents a newly discovered human species named Homo longi or "Dragon Man." Their findings, appearing in three papers publishing June 25 in the journal The Innovation, suggest that the Homo longi lineage may be our closest relatives--and has the potential to reshape our understanding of human evolution. "The Harbin fossil is one of the most complete human cranial fossils in the world," says author Qiang Ji, a professor of paleontology of Hebei GEO University. "This fossil preserved many ...

Antacids may improve blood sugar control in people with diabetes

2021-06-25
WASHINGTON--Antacids improved blood sugar control in people with diabetes but had no effect on reducing the risk of diabetes in the general population, according to a new meta-analysis published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. Type 2 diabetes is a global public health concern affecting almost 10 percent of people worldwide. Doctors may prescribe diet and lifestyle changes, diabetes medications, or insulin to help people with diabetes better manage their blood sugar, but recent data points to common over the counter ...

Changes in COVID-19-related hospitalizations, deaths after states reopened

2021-06-25
What The Study Did: This study evaluated changes in hospitalization and death rates related to COVID-19 before and after U.S. states reopened their economies in 2020. Authors: Pinar Karaca-Mandic, Ph.D., of the Carlson School of Management in Minneapolis, is the corresponding author. To access the embargoed study:  Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamahealthforum.2021.1262) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. INFORMATION: Media advisory: The full study ...

Association of childcare closures, employment of women vs men during COVID-19

2021-06-25
What The Study Did: Researchers examined the association of closures of childcare facilities with the employment status of women and men with children in the United States during the COVID-19 pandemic. Authors: Yevgeniy Feyman, B.A., of the Boston University School of Public Health, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamahealthforum.2021.1297) Editor's Note: The article includes funding/support disclosures. Please see the article for additional information, including other authors, author ...

Assessing COVID-19 control plan on University Campus during second wave of pandemic

2021-06-25
What The Study Did: This analysis describes the use of a multifaceted COVID-19 control plan to reduce spread of SARS-CoV-2 at a large urban university during the second wave of the pandemic. Authors: Davidson H. Hamer, M.D., of the Boston University School of Public Health, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2021.16425) Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and ...
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