Levelling up access to finance so that poorer countries can afford the funds needed to switch to renewable energy could see regions like Africa reaching net zero emissions a decade earlier, according to a study led by UCL researchers. Access to finance (credit) is vital for the green energy transition needed to reduce global greenhouse gas emissions, as laid out in the Paris Agreement. But access to low-cost finance is uneven, with the cost of securing capital to help reach net zero differing substantially between regions. Modelling created for the study, Higher cost of finance exacerbates a climate investment trap in developing economies, published in Nature Communications, ...

HOUSTON - The University of Texas MD Anderson Cancer Center's Research Highlights provides a glimpse into recently published studies in basic, translational and clinical cancer research from MD Anderson experts. Current advances include expanded use of a targeted therapy for a new group of patients with leukemia, molecular studies yielding novel cancer therapeutic targets, insights into radiation therapy resistance and a community intervention to reduce cervical cancer rates. Using acalabrutinib as initial treatment for chronic lymphocytic leukemia Chronic lymphocytic leukemia (CLL) is a cancer that occurs in the blood, bone marrow, lymph nodes, liver and spleen. It is the most common leukemia in adults, and while there are treatments ...

Heart attack, medically known as myocardial infarction (MI), is a common heart condition. MI is caused by problems in blood supply to parts of the heart. In severe cases, MI could be accompanied by ruptures in the wall separating different parts of the heart, such as in the ventricular septum (a wall that separates the right ventricle that pumps deoxygenated blood to the lungs for oxygenation, from the left ventricle that pumps oxygenated blood to rest of the body). Not surprisingly, without appropriate surgical intervention, a VSR due to MI increases the chances of death. Current surgical techniques ...

Bioplastics -- biodegradable plastics made from biological substances rather than petroleum -- can be created in a more economical and environmentally friendly way from the byproducts of corn stubble, grasses and mesquite agricultural production, according to a new study by a Texas A&M AgriLife Research scientist. green tractor pulling a red cart through a field of bioenergy sorghum that is taller than the tractor A bioenergy sorghum crop is harvested near College Station. (Texas A&M AgriLife photo) This new approach involves a "plug-in" preconditioning process, a simple adjustment for biofuel refineries, said Joshua Yuan, Ph.D., AgriLife Research scientist, ...

Dinosaurs roamed the Earth more than 65 million years ago, and paleontologists and amateur fossil hunters are still unearthing traces of them today. The minerals in fossilized eggs and shell fragments provide snapshots into these creatures' early lives, as well as their fossilization processes. Now, researchers reporting in ACS Earth and Space Chemistry have analyzed the molecular makeup of fossilized dinosaur eggshells from Mexico, finding nine amino acids and evidence of ancient protein structures. Current research indicates that all dinosaurs laid eggs, though most haven't survived the test of time. And because whole eggs and shell fragments are very rare fossils, their mineral composition ...

Newly published research shows that a screening program in the University of Cincinnati Medical Center Emergency Department helped detect an outbreak of HIV among persons who inject drugs in Hamilton County, Ohio, from 2014-18. The study was published in PLOS ONE. The results of the study highlight UC contributions to public health surveillance as yet another reason why emergency departments should be screening for undiagnosed HIV infections, according to Michael Lyons, MD, associate professor in the Department of Emergency Medicine at the UC College of ...

Some people casually smoke cigarettes for a while and then stop without a problem, while others develop long-term, several packs-per-day habits. A complex mix of environmental, behavioral and genetic factors appear to raise this risk for nicotine dependence. Studies of groups of twins suggest that 40 to 70 percent of the risk factors are heritable. Until recently, however, studies have only explained about 1 percent of the observed variation in liability to nicotine dependence, using a genetic score based on how many cigarettes a person smokes per day. A new study led by psychologists ...

Using an experimental model to simulate the blood-brain barrier, scientists in Sweden reported in unprecedented detail how antioxidants protect the brain from inflammation caused by neurodegenerative diseases such as Alzheimer's and Parkinson's. The study, conducted as a proof of concept by brain model developers at KTH Royal Institute of Technology in Stockholm, showed in minute-by-minute detail how the blood-brain barrier reacts to high levels of inflammation after the administration of a next-generation derivative of the widely-used anti-inflammatory drug, NAC (N-acetylcysteine). The testing of NACA (N-Acetylcysteine Amide) for the first time with ...

A new way to target a mutant protein which can cause the deadliest of cancers in humans has been uncovered by scientists at the University of Leeds. The mutated form of the RAS protein has been referred to as the "Death Star" because of its ability to resist treatments and is found in 96% of pancreatic cancers and 54% of colorectal cancers. RAS is a protein important for health but in its mutated form it can be switched on for longer, leading to the growth of tumours. One drug has already been approved for treatment but it can only tackle a small subset of ...

In a study involving 34 women aged 50-70, researchers at the University of São Paulo (USP) in Brazil performed objective measurements of the impact on the subjects' health of the decrease in physical activity observed during the period of social distancing and isolation imposed by COVID-19. Tests conducted after the first 16 weeks of confinement pointed to a deterioration in their overall health, including loss of muscle strength and diminished aerobic capacity, as well as elevated levels of cholesterol and glycated hemoglobin, both of which are risk factors for metabolic disorders. The study was supported by São Paulo Research Foundation ...

When it comes to understanding and predicting trends in energy use, the internet is a tough nut to crack. So say energy researchers Eric Masanet, of UC Santa Barbara, and Jonathan Koomey, of Koomey Analytics. The two just published a peer-reviewed commentary in the journal Joule discussing the pitfalls that plague estimates of the internet's energy and carbon impacts. The paper describes how these errors can lead well-intentioned studies to predict massive energy growth in the information technology (IT) sector, which often doesn't materialize. "We're not saying the energy use of the internet isn't a ...

CHAMPAIGN, Ill. -- The chance of detecting the virus that causes COVID-19 increases with more frequent testing, no matter the type of test, a new study found. Both polymerase chain reaction and antigen tests, paired with rapid results reporting, can achieve 98% sensitivity if deployed at least every three days. "This study shows that frequent testing can be really effective at catching COVID-19 infections and potentially blocking transmission," said study leader Christopher Brooke, a virologist and professor of microbiology at the University of Illinois Urbana-Champaign. "There are many places where vaccination is not yet widespread. With the rise of variants, testing remains an important tool ...

QUT researchers have developed a new machine learning mathematical system that helps to identify and detect changes in biodiversity, including land clearing, when satellite imagery is obstructed by clouds. Using statistical methods to quantify uncertainty, the research, published in Remote Sensing in Ecology and Conservation, analysed available satellite images of an 180km square area in central south-east Queensland. The region is home to many native species including the critically endangered northern hairy-nosed wombat and the vulnerable greater glider, and the ...

Fossilized feces are common finds at paleontological dig sites and might actually contain hidden treasures. By scanning fossilized dung assigned to a close dinosaur relative from the Triassic period, scientists discovered a 230-million-year-old beetle species, representing a new family of beetles, previously unknown to science. The beetles were preserved in a 3D state with their legs and antennae fully intact. The finding appears June 30 in the journal Current Biology. The discovery that fossilized droppings, also known as coprolites, can preserve ancient insect species offers a new alternative to amber fossils--fossilized tree resin, which normally yield the best-preserved insect fossils. The oldest ...

Don't let the great snipe's pudginess fool you. A stocky marsh bird with a 20-inch wingspan, great snipes are also speedy marathoners that can migrate from Sweden to Central Africa in just three days, without even stopping to eat, drink, or sleep. Now, researchers find that the snipes also rise nearly 2,500 meters in elevation at dawn and descend again at dusk each day, perhaps to avoid overheating from daytime solar radiation by climbing to higher, cooler altitudes. The findings appear June 30 in the journal Current Biology. The birds also spent much more time in higher elevations ...

Election outcomes are notoriously difficult to predict. In 2016, for example, most polls suggested that Hillary Clinton would win the presidency, but Donald Trump defeated her. Researchers cite multiple explanations for the unreliability in election forecasts -- some voters are difficult to reach, and some may wish to remain hidden. Among those who do respond to surveys, some may change their minds after being polled, while others may be embarrassed or afraid to report their true intentions. In a new perspective piece for END ...

30 June 2021: A large cohort study drawn from the national IVF registry of France, which included almost 70,000 pregnancies delivered after 22 weeks gestation between 2013 and 2018, has found a higher risk of pre-eclampsia and hypertension in pregnancies derived from frozen-thawed embryos. This risk was found significantly greater in those treatments in which the uterus was prepared for implantation with hormone replacement therapies. The results confirm with real-life data what has been observed in sub-groups of patients in other studies. The results are presented today by Dr Sylvie Epelboin from the Hôpital Bichat-Claude Bernard, Paris, at the online annual meeting of ESHRE. The study was performed on behalf ...

The tiny beetle Triamyxa coprolithica is the first-ever insect to be described from fossil faeces. The animal the researchers have to thank for the excellent preservation was probably the dinosaur ancestor Silesaurus opolensis, which 230 million years ago ingested the small beetle in large numbers. In a recently published study in Current Biology, vertebrate palaeontologists from Uppsala University and entomologists from National Sun Yat-sen University (Taiwan), Friedrich-Schiller-Universität Jena (Germany), and Universidad de Guadalajara (Mexico) used synchrotron microtomography to 3D-reconstruct the beetles while they were still trapped within the fossilised faecal matter. The coprolite contained abundant beetle body parts, most belonging to ...

Harpy eagles (Harpia harpyja) - which are among the world's largest eagle species - struggle to feed offspring in heavily deforested areas of the Amazon, according to a study published in Scientific Reports. Everton Miranda and colleagues found that harpy eagles rely on specific prey that lives in canopy forests, including sloths and monkeys. Eaglets starved in areas of high deforestation where canopy-based food was limited. The authors observed prey species, how frequently prey was delivered, and estimated the weight of prey in 16 harpy eagle nests in Amazonian forests in Mato ...

ROCKVILLE, MD, USA - June 30, 2021 - Researchers from Sanaria® Inc. and the National Institutes of Health (NIH) are making progress in the development of highly protective malaria vaccines. In an article published today in Nature, Sanaria's PfSPZ-CVac (CQ) vaccine is reported as being safe and protecting 100% of six subjects against a variant malaria parasite three months after their last dose in the company's Phase 1 safety and efficacy trial. This is the first time complete protection against a variant malaria parasite has ever been achieved that long after vaccine administration. The ...

Many neurodevelopmental disorders share similar symptoms, such as learning disabilities or attention deficits. A new study from MIT has uncovered a common neural mechanism for a type of cognitive impairment seen in some people with autism and schizophrenia, even though the genetic variations that produce the impairments are different for each condition. In a study of mice, the researchers found that certain genes that are mutated or missing in some people with those disorders cause similar dysfunctions in a neural circuit in the thalamus. If scientists could develop drugs that target this circuit, they could be used to treat people who have different disorders with common behavioral ...

In 1934, physicist Eugene Wigner made a theoretical prediction based on quantum mechanics that for 87 years went unseen. The theory suggested how a metal that normally conducts electricity could turn into a nonconducting insulator when the density of electrons is reduced. Wigner theorized that when electrons in metals are brought to ultracold temperatures, these electrons would be frozen in their tracks and form a rigid, non-electricity conducting structure -- a crystal -- instead of zipping around at thousands of kilometers per second and creating an electric current. Since he discovered it, the ...

Researchers have found that eating disorder behaviors, such as binge-eating, alter the brain's reward response process and food intake control circuitry, which can reinforce these behaviors. Understanding how eating disorder behaviors and neurobiology interact can shed light on why these disorders often become chronic and could aid in the future development of treatments. The study, published in JAMA Psychiatry, was supported by the National Institutes of Health. "This work is significant because it links biological and behavioral factors that interact to adversely impact eating behaviors," said Janani Prabhakar, ...

Neuroscientists at UCL have, for the first time, identified abnormalities in the way memories are 'replayed' in the brains of people with schizophrenia; researchers say the pathbreaking study provides an entirely new basis for explaining many of the condition's core symptoms. Schizophrenia is a serious and debilitating mental disorder characterised by episodes of psychosis. Symptoms include hallucinations (typically hearing voices), delusions, and disorganised thinking. It affects around 20 million people globally, though the exact cause is unknown. In the study, published in the journal Cell, researchers used state-of-the-art ...

A new study by investigators from Brigham and Women's Hospital examines the associations between wealth mobility and long-term cardiovascular health. The multidisciplinary study borrowed methodology from the field of economics to analyze longitudinal changes in wealth. The team's results indicate that negative wealth mobility is associated with an increased risk of cardiovascular events, while positive wealth changes are associated with a decreased risk of cardiovascular events. Their results are published in END ...