Researchers have discovered a new avenue of cell death in Alzheimer’s disease and vascular dementia. A new study, led by scientists at Oregon Health & Science University and published online in the journal Annals of Neurology on Aug. 21, reveals for the first time that a form of cell death known as ferroptosis — caused by a buildup of iron in cells — destroys microglia cells, a type of cell involved in the brain’s immune response,  in cases of Alzheimer’s and vascular dementia. The ...

Reston, VA—The Society of Nuclear Medicine and Molecular Imaging (SNMMI) has issued a new consensus statement to provide standardized guidance for the selection and management of metastatic castrate-resistant prostate cancer (mCRPC) patients being treated with 177Lu-PSMA radionuclide therapy. The statement, published in the July issue of The Journal of Nuclear Medicine, also reviews current clinical struggles physicians face during treatment with 177Lu-PSMA-617 radionuclide therapy. Recently, the U.S. Food and Drug Administration approved 177Lu-PSMA-617 for the treatment of men with mCRPC after progressing on taxane-based chemotherapy ...

Plant-based alternatives such as tempeh and bean burgers provide protein-rich options for those who want to reduce their meat consumption. However, replicating meat's flavors and aromas has proven challenging, with companies often relying on synthetic additives. A recent study in ACS’ Journal of Agricultural and Food Chemistry unveils a potential solution: onions, chives and leeks that produce natural chemicals akin to the savory scents of meat when fermented with common fungi. When food producers want to make plant-based meat alternatives taste ...

When we determine which communities are more likely to get their water from contaminated supplies, median household income is not the best measure. That’s according to a recent study led by researchers at The University of Texas at Austin that found social factors — such as low population density, high housing vacancy, disability and race — can have a stronger influence than median household income on whether a community’s municipal water supply is more likely to have health-based water-quality violations. In general, rural communities and communities that grew up around large industries that have since left are most likely to face water-quality issues. About 10% ...

A team of scientists from Ames National Laboratory developed a new machine learning model for discovering critical-element-free permanent magnet materials. The model predicts the Curie temperature of new material combinations. It is an important first step in using artificial intelligence to predict new permanent magnet materials. This model adds to the team’s recently developed capability for discovering thermodynamically stable rare earth materials. High performance magnets are essential for technologies such as wind energy, data storage, electric vehicles, ...

“Overall, our study identified previously unknown circadian transcriptome reorganization of pancreas by aging [...]” BUFFALO, NY- September 5, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 16, entitled, “Reorganization of pancreas circadian transcriptome with aging.” The evolutionarily conserved circadian system allows organisms to synchronize internal processes with 24-h cycling environmental timing cues, ensuring optimal adaptation. Like other organs, the pancreas function is under circadian control. Recent evidence ...

Invasive medical procedures, such as surgery requiring local anesthesia, often involve the risk of nerve injury. During operation, surgeons may accidentally cut, stretch, or compress nerves, especially when mistaking them for some other tissue. This can lead to long-lasting symptoms in the patient, including sensory and motor problems. Similarly, patients receiving nerve blockades or other types of anesthesia can suffer from nerve damage if the needle is not placed at the correct distance from the targeted peripheral nerve. Consequently, researchers have been trying to develop medical imaging techniques to mitigate the risk of nerve damage. For instance, ultrasound and magnetic resonance ...

LOS ANGELES – Almost one-third of government appointees to the Department of Health and Human Services (HHS) leave to take jobs in private industry, according to a study by the USC Schaeffer Center for Health Policy & Economics and Harvard University. The study, published in Health Affairs, is the first to quantify the personnel movement between health-care industries and the government agencies that regulate them, according to the authors. Although there are understandable reasons for people to move between the public and private sectors, the study notes that such a revolving door could make government agencies more vulnerable to pro-industry bias. “Laws passed ...

The use of direct oral anticoagulants (DOACs) was associated with a reduction in dementia risk compared to traditional blood thinners—like warfarin—in atrial fibrillation patients, particularly in Asian patients. According to a study published today in JACC: Asia, this benefit may reverse with increased age and necessitates further follow-up study. “Asian patients are more likely to be sensitive to vitamin K antagonism, which puts them at high risk for bleeding events, contributing to dementia development ...

ITHACA, N.Y. – Male fruit flies don’t usually like each other. Socially, they reject their fellow males and zero in on the females they discern via chemical receptors – or so scientists thought. New research from Cornell University biologists suggests the fruit fly’s visual system, not just chemical receptors, are deeply involved with their social behaviors. The work sheds light on the possible origin of differences in human social behaviors, such as those seen in people with bipolar disorder ...

New research from Tulane University may shed light on how parasite strain diversity can impact Chagas disease progression and severity. Chagas, a lesser-known and studied tropical disease,  is caused by Trypanosoma cruzi parasites, which are transmitted by kissing bugs. In the Americas, the disease affects 6 million people in 21 countries, with approximately 30,000 new cases each year. While most infected patients remain asymptomatic, about 20-40 percent of those infected will develop chronic heart disease ...

New simulations model traffic-related air pollution over the region surrounding Chicago, North America’s largest freight hub In the simulations, the researchers modeled a scenario in which 30% of current on-road heavy-duty vehicles (HDVs) were replaced by electric HDVs Electrifying HDVs would substantially reduce air pollution and save hundreds of lives annually in the region, with particularly large health benefits in predominantly Black, Hispanic and Latinx communities  The region also would save nearly $6 billion annually in avoided ...

The diagnosed severity of aortic stenosis strongly correlates with clinical outcomes, new Kaiser Permanente research shows. But the study also suggests that fine-tuning physician assessment of those patients with moderate aortic stenosis could help improve outcomes and better determine which patients might benefit from surgery. The study found that patients diagnosed with moderate aortic stenosis have outcomes most similar to those categorized with mild aortic stenosis while only those with moderate-to-severe aortic stenosis had outcomes similar to those with ...

The University of Miami School of Nursing and Health Studies (SONHS) has been awarded an unprecedented $23.57 million grant from the National Institutes of Health (NIH) to join the Environmental influences on Child Health Outcomes (ECHO) Program. The interdisciplinary grant, the largest award to date in the Coral Gables Campus’ history, is funding an ambitious project spearheaded by Hudson Santos, RN, PhD, FABMR, FAAN, the lead Principal Investigator and Vice Dean for Research Affairs, with Professor Michael Paidas, MD, chair of the University of Miami Miller School of Medicines Department of Obstetrics, ...

New research shows that Allied Health Professions (AHPs) are significantly underrepresented in senior leadership roles despite being the third largest workforce in the NHS. Ranging from paramedics to podiatrists, the AHPs encompass various healthcare disciplines, constituting a workforce of 185,000 within the NHS. However AHPs have historically been underrepresented in strategic leadership positions, often occupied by medical professionals. To address this, NHS England advocated for the establishment of a Chief AHP role in every Trust to harness the untapped potential of this workforce and increase diversity in leadership ...

WASHINGTON, D.C.—Food costs decrease 16% on a low-fat vegan diet, a savings of more than $500 a year, compared to a diet that includes meat, dairy, and other animal products, according to a new analysis from the Physicians Committee for Responsible Medicine published in JAMA Network Open. “We knew that a vegan diet significantly reduces your risk of conditions like heart disease, diabetes, and obesity—and now we have proof that opting for beans instead of beef will also lead to significant savings on your grocery bill,” says study co-author Hana Kahleova, ...

Having more positive body image is strongly associated with better psychological wellbeing and life satisfaction, according to a new study led by Anglia Ruskin University (ARU) in England.   Published in the journal Body Image, the research is one of the largest studies ever conducted on the topic of body image, involving 56,968 participants in 65 nations.   The research was focused on ‘body appreciation’, defined as “accepting, holding favourable opinions toward, and respecting the body, while also rejecting media-promoted appearance ...

Alexandria, VA -- The American Association for Dental, Oral, and Craniofacial Research (AADOCR) is pleased to announce the program participants (mentees) for the fourth cohort of the AADOCR Mentoring an Inclusive Network for a Diverse Workforce of the Future (AADOCR MIND the Future): Shaun Abrams NIH/NIDCR, Bethesda, MD Craniofacial development, anomalies, stem cell biology Jean Calvo University of California, San Francisco Pediatric dentistry, dental education, patient safety, individuals with special needs Louise M. Dornelas-Figueira University of Florida, Gainesville Oral ...

American Geophysical Union 5 September 2023 Release 23-33 For Immediate Release This press release is available online at: https://news.agu.org/press-release/disparities-in-who-dwells-behind-us-levees/ Key points: Tens of millions of people live in areas protected by at least one levee in the United States Nationally, members of historically disadvantaged or underserved groups are more likely to be overrepresented in communities living behind levees People of Hispanic descent are most likely to be overrepresented behind levees, with ~40% overrepresentation ...

LOS ANGELES — Keck Medicine of USC has named Chris Allen chief financial officer (CFO), effective Aug. 31. He previously served as interim CFO of Keck Medicine and CFO of Keck Medical Center of USC.  In this role, Allen will continue to oversee Keck Medicine’s strategic financial plans, financial and governmental reporting, budgeting, funds flow, revenue cycle and material management. He will also lead the assessment, planning, implementation and evaluation of the health system’s financial ...

Taylor M. Anderson, Assistant Professor, Geography and Geoinformation Science, and Amira Roess, Professor, Global Health and Epidemiology, are studying zoonotic transmission pathways.  Specifically, the researchers received funding for the project: "Investigating zoonotic transmission pathways to better understand and predict the spread of SARS-CoV-2 in urban and suburban landscapes: a case study of the white-tailed deer."  They aim to investigate unknown transmission pathways at the human-wildlife interface in urban ...

Resistant starch is a nondigestible fiber that ferments in the large intestine, and consumption of it has previously been shown to have a positive effect on metabolism in animal studies. Now, a 4-month randomized controlled trial in people with non-alcoholic fatty liver disease (NAFLD) indicates that daily intake of resistant starch can alter gut bacteria composition and lower liver triglycerides and liver enzymes associated with liver injury and inflammation. This research appears in the journal Cell Metabolism on September 5. NAFLD, caused by a buildup of fat in the liver, affects about 30% of the population worldwide. It can lead ...

WASHINGTON, Sept. 5, 2023 -- Traveling to faraway places is a great way to seek out new experiences, but jet lag can be an unpleasant side effect. Adjusting to a new time zone is often accompanied by fatigue, difficulty sleeping, and a host of other problems that can turn an otherwise exciting adventure into a miserable trip. Jet lag is caused by a difference between the circadian system — the body’s internal clock — and the surrounding environment. Around the turn of the century, scientists began to recognize that the body has multiple internal clocks, calibrated in different ways, and that jet lag-like symptoms can result when these ...

About The Study: This study found that between 1995 and 2020, U.S. preterm infant mortality improved among all categories of prematurity. Inequalities in preterm infant mortality based on maternal race and ethnicity have remained constant while socioeconomic disparities have widened over time.  Authors: Tim Venkatesan, M.A. (Cantab), M.B., B.Chir., D.T.M.&H., of the UCL Great Ormond Street Institute of Child Health in London, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2023.3487) Editor’s ...

About The Study: In this study of 633,000 children treated in 586 emergency departments across 11 states, mortality of Black children was greater than that of white children at all quartile levels of readiness among those with acute medical emergencies but not traumatic injuries. Increased readiness was associated with decreased mortality overall, and it decreased most for Black children with acute medical emergencies.  Authors: Peter C. Jenkins, M.D., M.Sc., of the Indiana University School of Medicine in Indianapolis, is the corresponding ...