Newly published research contained in the Special Issue of the Journal of Marketing features fourteen global author teams focused on the topic of Better Marketing for a Better World. Edited by Rajesh Chandy (London Business School), Gita Johar (Columbia University), Christine Moorman (Duke University), and John Roberts (University of New South Wales), this Special Issue brings together wide-ranging research to assess, illuminate, and debate whether, when, and how marketing contributes to a better world. The Special Issue is built on the thesis that marketing has the power to improve lives, sustain livelihoods, strengthen societies, and benefit the world at large. It calls for a renewed ...

PORTLAND, Ore. - Policies designed to prevent the misuse of opioids may have the unintended side effect of limiting access to the pain-relieving drugs by terminally ill patients nearing the end of their life, new research led by the Oregon State University College of Pharmacy suggests. A study of more than 2,500 hospital patients discharged to hospice care over a nine-year period showed a decreasing trend of opioid prescriptions as well as an increase in the prescribing of less powerful, non-opioid analgesics, meaning some of those patients might have been undertreated for their pain compared to similar patients in prior years. The findings, published in the Journal of Pain and Symptom Management, are an important step toward optimizing ...

Philadelphia, April 20, 2021 - A collaborative study from the Center for Injury Research and Prevention (CIRP) and the Center for Autism Research (CAR) at Children's Hospital of Philadelphia (CHOP) identified clear strengths and a series of specific challenges autistic adolescents experience while learning to drive. The findings were recently published by the American Journal of Occupational Therapy. Researchers conducted in-depth interviews with 17 specialized driving instructors who were trained as occupational therapists, driving rehabilitation specialists, or licensed driving instructors and who had completed additional training related ...

Flushing a toilet can generate large quantities of microbe-containing aerosols depending on the design, water pressure or flushing power of the toilet. A variety of pathogens are usually found in stagnant water as well as in urine, feces and vomit. When dispersed widely through aerosolization, these pathogens can cause Ebola, norovirus that results in violent food poisoning, as well as COVID-19 caused by SARS-CoV-2. Respiratory droplets are the most prominent source of transmission for COVID-19, however, alternative routes may exist given the discovery of small numbers of viable viruses in urine and stool samples. Public restrooms are especially cause for concern for transmitting COVID-19 because they are ...

A new UCLA study finds that the proportion of physicians who are Black in the U.S. has increased by only 4 percentage points over the past 120 years, and that the share of doctors who are Black men remains unchanged since 1940. The research also spotlights a significant income gap between white and Black male physicians -- a disparity, the researcher writes, that could reflect a combination of pay discrimination and unequal access for physicians to pursue careers in more lucrative specialties. The paper will be published April 19 in the peer-reviewed Journal of General Internal Medicine. "These findings demonstrate how slow progress has been, and how far and fast we have to go, if we care about the diversity of the physician workforce and the health benefits such diversity brings ...

COLUMBUS, Ohio - A high daily dose of an omega-3 supplement may help slow the effects of aging by suppressing damage and boosting protection at the cellular level during and after a stressful event, new research suggests. Researchers at The Ohio State University found that daily supplements that contained 2.5 grams of omega-3 polyunsaturated fatty acids, the highest dose tested, were the best at helping the body resist the damaging effects of stress. Compared to the placebo group, participants taking omega-3 supplements produced less of the stress hormone cortisol and lower levels of a pro-inflammatory protein during a stressful event in the lab. And while levels of protective compounds sharply declined in the placebo group after the stressor, there were ...

A Monash University study has uncovered for the first time a way to prevent and reverse damage caused by broken-heart syndrome, also known as Takotsubo cardiomyopathy. Using mouse models, the pre-clinical study published in the acclaimed journal Signal Transduction and Targeted Therapy, has shown the cardioprotective benefit of a drug called Suberanilohydroxamic acid, or SAHA, dramatically improved cardiac health and reversed the broken-heart. The landmark study used SAHA to target genes and is a world first for Takotsubo cardiomyopathy. SAHA, currently used for cancer treatment, is approved by the US Food and Drug Administration (FDA) and Australian Therapeutic Goods Administration (TGA), works by providing a protective benefit to genes and ...

For the first time, a study has shown a clear link between the frequency and duration of unconscious wakefulness during night-time sleep and an increased risk of dying from diseases of the heart and blood vessels, and death from any cause, particularly in women. The study of 8001 men and women, which is published today (Tuesday) in the European Heart Journal [1], found that women who experienced unconscious wakefulness most often and for longer periods of time had nearly double the risk of dying from cardiovascular disease during an average of between 6 and 11 years' ...

Taking multivitamins, omega-3, probiotics or vitamin D supplements may lessen the risk of testing positive for SARS-CoV-2, the virus responsible for COVID-19 infection--at least among women--indicates a large population study, published online in the journal BMJ Nutrition Prevention & Health. But taking any of vitamin C, zinc, or garlic supplements wasn't associated with a lower risk of testing positive for the virus, the findings show. There has been plenty of celebrity endorsement of the use of dietary supplements to both ward off and treat COVID-19 infection since the start of the pandemic, note the researchers. In the UK alone, market share ...

Nanochannels have important applications in biomedicine, sensing, and many other fields. Though engineers working in the field of nanotechnology have been fabricating these tiny, tube-like structures for years, much remains unknown about their properties and behavior. Now, University of Maryland mechanical engineering associate professor Siddhartha Das and a group of his Ph.D. students have published surprising new findings in the journal ACS Nano. Using atomic-level simulations, Das and his team were able to demonstrate that charge properties as well as charge-induced fluid flow within a functionalized nanochannel does not always behave as expected. "We've discovered a new context for nanochannels functionalized by grafting ...

One of the marks of a successful idea in science is how quickly it can develop and evolve. In the case of the Anthropocene, the conceptual evolution has taken place with extraordinary speed. The strikingly influential hypothesis launched by the late Nobel laureate Paul Crutzen (Obituary, 24th Feb 2021) in 2000, was that the actions of an industrialised humanity has impacted the Earth so greatly as to trigger a new geological epoch. Originally developed within the Earth System science community in charting global environmental change, the Anthropocene then began ...

April 19, 2021 -- Ensuring COVID-19 vaccine access for refugee and displaced populations, and addressing health inequities, is vital for an effective pandemic response. Yet, vaccine allocation and distribution has been neither equitable nor inclusive, despite that global leaders have stressed this as a critical aspect to globally overcoming the pandemic, according to a paper published by Columbia University Mailman School of Public Health. Read "Leave No-one Behind: Ensuring Access to COVID-19 vaccines for Refugee and Displaced Populations" in the journal Nature Medicine. As of April 1st, high and upper-middle-income countries received 86 percent of the vaccine doses delivered worldwide, while ...

Tools that allow neuroscientists to record and quantify functional activity within the living brain are in great demand. Traditionally, researchers have used techniques such as functional magnetic resonance imaging, but this method cannot record neural activity with high spatial resolution or in moving subjects. In recent years, a technology called optogenetics has shown considerable success in recording neural activity from animals in real time with single neuron resolution. Optogenetic tools use light to control neurons and record signals in tissues that are genetically modified ...

A group of scientists have just made a key discovery that could prevent and eradicate immune responses that lead to treatment failure in about one-third of people with severe hemophilia A. Hemophilia is the most common severe inherited bleeding disorder in men. The disease affects 1 in 10,000 males worldwide and results from deficiency of blood clotting factor VIII (FVIII). Both children and adults with hemophilia A (80 percent of all hemophilia) receive treatment that involves infusing FVIII protein into the bloodstream. However, about 30 percent ...

Our planet's worst mass extinction event happened 252 million years ago when massive volcanic eruptions caused catastrophic climate change. The vast majority of animal species went extinct, and when the dust settled, the planet entered the early days of the Age of Dinosaurs. Scientists are still learning about the patterns of which animals went extinct and which ones survived, and why. In a new study in PNAS, researchers found that while extinctions happened rapidly in the oceans, life on land underwent a longer, more drawn-out period of extinctions. "People assumed that because the marine extinction happened over a short period of time, life on land should have followed the same pattern, but we found that the marine extinction ...

Professor Nicole Boivin, Director of the Department of Archaeology at the Max Planck Institute for the Science of Human History in Jena, Germany, is part of an international initiative to examine the implications of past land use for contemporary conservation efforts. The multi-disciplinary team, which includes archaeologists, ecologists, anthropologists and conservation managers, has reconstructed ancient population and land use to show that already by 12,000 years ago, humans had re-shaped much of the terrestrial biosphere. Their data challenge the idea that conservation ...

New research published today in the Proceedings of the National Academy of Sciences (PNAS) shows that land use by human societies has reshaped ecology across most of Earth's land for at least 12,000 years. The research team, from over ten institutions around the world, revealed that the main cause of the current biodiversity crisis is not human destruction of uninhabited wildlands, but rather the appropriation, colonization, and intensified use of lands previously managed sustainably. The new data overturn earlier reconstructions of global land use history, some of which indicated that most of Earth's land was uninhabited even as recently as 1500 CE. Further, ...

Diversity in diet plays a role in the complexity of venom in pit vipers such as rattlesnakes, copperheads and cottonmouths. But new collaborative research by Clemson University scientists found the number of prey species a snake ate did not drive venom complexity. Rather, it was how far apart the prey species were from each other evolutionarily. "It's not just diet that drives the variation in venom across snakes. It's the breadth of diet," said Christopher Parkinson, a professor in the College of Science's Department of Biological Sciences. "If a snake eats 20 different species of mammals, its venom will not be very complex. But if it eats a centipede, a frog, a bird and a mammal, it's going to have a highly complex venom because each component of that venom ...

Antibiotics on the cocoon protect the offspring of beewolves, a group of digger wasps, from detrimental fungi. These protective substances are produced by symbiotic bacteria of the genus Streptomyces, which live in these insects. In a new study in PNAS, researchers from the Max Planck Institute for Chemical Ecology and the University of Mainz, together with an international team, showed that these beneficial bacteria are losing genetic material that is no longer needed. The genome of these bacteria is of great interest for understanding the process of genome erosion and elucidating how the cooperation and the mutual benefit between bacteria and their host insects have evolved over long periods of time (PNAS, doi: 10.1073/pnas.2023047118, ...

Police violence against Black Americans is shamefully common in the United States and devastates communities. For incidents that get widespread media exposure, a collective trauma is felt across the nation, especially for Black individuals. Research supports that experiencing racism even vicariously can harm the mental and physical health of others of the same racial group, yet its effect on a population level is unclear. A new study analyzed how highly publicized acts of racial violence impacted the mental health of Black Americans in the U.S. The authors identified 49 incidents that occurred between 2013 and 2017, including police killings of Black individuals, hate-crime murders and decisions not to indict or convict the officers involved. The researchers measured ...

What keeps some plants squatting close to the soil while others - even those closely related - reach high for the skies? New research addressing the architecture and growth habit of plants has provided an answer to this question and may assist in the development of better performing crops. The way plants grow must sometimes satisfy contradictory needs. Growing close to the ground, decreases the chances of being grazed, but this presents the need to rise rapidly to allow seeds to disperse. This can be observed in dandelions and in Arabidopsis, a model species commonly used to study plant development. Agriculture has taken advantage of the diversification of growth habit so that ...

Like superheroes capable of seeing through obstacles, environmental regulators may soon wield the power of all-seeing eyes that can identify violators anywhere at any time, according to a new Stanford University-led study. The paper, published the week of April 19 in Proceedings of the National Academy of Sciences (PNAS), demonstrates how artificial intelligence combined with satellite imagery can provide a low-cost, scalable method for locating and monitoring otherwise hard-to-regulate industries. (WATCH VIDEO: https://www.youtube.com/watch?v=LHvRgKmJOK8) "Brick kilns have proliferated across Bangladesh to supply the growing economy with construction materials, which makes it really hard for regulators to keep up with new kilns that are constructed," ...

A new type of collective behaviour in ants has been revealed by an international team of scientists, headed by biologist Professor Iain Couzin, co-director of the Cluster of Excellence "Centre for the Advanced Study of Collective Behaviour" at the University of Konstanz and director at the co-located Max Planck Institute of Animal Behavior, and Matthew Lutz, a postdoctoral researcher in Couzin's lab. Their research shows how ants use self-organized architectural structures called "scaffolds" to ensure traffic flow on sloped surfaces. Scaffold formation results from individual sensing and decision-making, ...

Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner. Researchers found that female mice with glioma that lacked the gene survived less than males. This led them to investigate human glioma cells, where they found that low POT1 expression correlated with reduced survival in females. Published in the journal Cancer Research, the study also shows that, compared to males', female tumors had reduced expression of immune signatures and increased expression of cell replication markers, suggesting that the immune response and tumor cell proliferation seemed to be ...

Scientists at VCU Massey Cancer Center have identified a protein that operates in tandem with a specific genetic mutation to spur lung cancer growth and could serve as a therapeutic target to treat the disease. Mutations in the p53 gene are found in more than half of all cancers, but it remains difficult to effectively target the gene with drugs even decades after its discovery. Though previous research has shown that p53 acts as a tumor suppressor and initiates cancer cell death in its natural state, a new study led by Sumitra Deb, Ph.D., suggests that gain-of-function (GOF) mutations -- a type of mutation where the changed gene has an added function ...