The National Institute of Allergy and Infectious Diseases has awarded the Icahn School of Medicine at Mount Sinai a five-year, $13 million grant to bring together experts from multiple disciplines across five research institutions to create better vaccines against current as well as emerging coronaviruses.  The COVID-19 pandemic, caused by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), has infected 280 million people and caused more than five million deaths worldwide since late 2019. While considerable progress has been made to develop interventions (i.e., monoclonal antibodies, antivirals, vaccines) to treat and prevent COVID-19, ...

In the ever-perilous autoimmune disease world of systemic lupus erythematosus (SLE or lupus), up to 60% of adult patients and 80% of children will develop lupus nephritis (LN), and up to half of those will move on to end-stage renal disease. LN occurs when the immune system wrongly attacks the kidneys, preventing them from doing their job, i.e., cleaning blood, balancing body fluids and controlling hormones that impact blood pressure.  Unfortunately, the most precise way to diagnose LN hasn’t been ...

“The molecular mechanisms that mediate enhanced dysfunction of white matter parenchymal arterioles when vascular dysfunction and ADNC coincide remain elusive.” BUFFALO, NY- September 12, 2023 – A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 16, entitled, “Microvascular contributions to white matter injury in Alzheimer’s disease.” In their new editorial, researchers Zsolt Bagi, ...

Since its inception in 2021, the African BioGenome Project (AfricaBP), has made significant gains towards its ambitious goal of sequencing 100,000 endemic African species within the next 10 years. Recently, AfricaBP reported the successful implementation of the Open Institute in the journal Nature Biotechnology (https://rdcu.be/dlXYT), a pioneering biodiversity genomics and bioinformatics knowledge exchange programme. The AfricaBP Open Institute’s framework will establish openly accessible workshops across Africa, crafted in close collaborations with local African Institutions. ...

The Institute of Science and Technology Austria (ISTA) is offering science journalists the opportunity for a paid three-month "Journalist in Residence“ program starting in April 2024. Applications are open until Oct. 31, 2023. The Institute of Science and Technology Austria (ISTA) in Klosterneuburg – in the immediate vicinity of Vienna – is a Ph.D.-granting research institute. Opened in 2009, the Institute is dedicated to basic research in the natural sciences, mathematics and computer sciences. It has a total of 1000 employees and 75 different research ...

An article published in NPJ Aging, a Springer Nature journal, reveals that natural production of auto-antibodies increases with age and that infection by SARS-CoV-2 can exacerbate production of auto-antibodies relating to auto-immune diseases, helping to explain why aging increases the chances of developing severe COVID-19. The study also discovered some of the factors that associate the severe form of the disease with blood clotting disorders such as thrombosis. “These findings open the door to a better ...

BIRMINGHAM, Ala. – In the summer of 2018, graduate student Hunter Dean from the Medical Scientist Training Program came to Yuhua Song, Ph.D., with a research idea. He wanted to pursue his doctoral research at the University of Alabama at Birmingham in Alzheimer’s disease — under the joint mentorship of Song, who had never worked in Alzheimer’s, and Erik Roberson, M.D., Ph.D., an Alzheimer’s expert in the UAB Department of Neurology and the Center for Neurodegeneration and Experimental Therapeutics, or CNET. That collaboration brought Song, a professor in the UAB Department of ...

Today, the National Comprehensive Cancer Network® (NCCN®)—an alliance of leading cancer centers—presented new recommendations for screening and addressing health-related social needs (HRSN) in people with cancer during a policy summit in Washington, D.C. The event included a keynote address from Ellen Lukens, Deputy Administrator and Director, The Center for Medicare and Medicaid Innovation (CMMI), and other speakers representing a diverse group of patient advocates, providers, and policymakers. The new recommendations for measuring and addressing HRSNs were ...

WASHINGTON, D.C. — September 12, 2023 — More than 40% of Americans say nursing homes are unsafe and 7 in 10 say they would be uncomfortable ever having to be admitted to one even if they needed such care, while more than six in 10 (61%) feel similarly anxious about the prospect of admitting family members, according to the latest survey from West Health and Gallup.     Safety was a particular area of perceived concern; 41% of respondents say nursing homes are not safe, 26% say they are, and about a third say they don’t know. Notably, the survey found that people over 35 were much ...

An abstract unveiling a new mouse model for brain arteriovenous malformations (AVMs) developed by UTHealth Houston researchers has been selected for a poster presentation at the second annual National Institutes of Health (NIH) Investigator Meeting for Interoception Research in November. Eunsu Park, PhD, assistant professor in the Vivian L. Smith Department of Neurosurgery with McGovern Medical School at UTHealth Houston, will present the abstract at the meeting, hosted by the National Center for Complementary and Integrative Health (NCCIH) at the NIH campus in Bethesda, Maryland, on Nov. ...

Perovskite solar cells should be subjected to a combination of stress tests simultaneously to best predict how they will function outdoors, according to researchers at the U.S. Department of Energy’s National Renewable Energy Laboratory (NREL). Solar cells must endure a set of harsh conditions—often with variable combinations of changing stress factors—to judge their stability, but most researchers conduct these tests indoors with a few fixed stressing conditions. While these tests provide some necessary insight, understanding which stressor applied during indoor tests provided predictive correlations ...

September 12, 2023 Toronto - It’s commonly accepted that U.S. and Chinese companies treat financial reporting and disclosure differently. New research not only confirms that but digs into the motivations behind the distinction, using surveys with more than 200 Chinese executives who hold reporting responsibility. An overriding interest in communicating long-term stability and inspiring confidence in the company’s prospects among a diverse range of stakeholders, and not primarily shareholders, as in the U.S., was a signature driver for the Chinese business leaders. “Acknowledging differences in approaches and incentives ...

DENVER/Sept. 12, 2023 – Recent findings from the Golden Retriever Lifetime Study confirm the enormous impact of hemangiosarcoma on golden retrievers. To address critical gaps in disease detection and treatment, Morris Animal Foundation announced it is funding six studies focused on this deadly form of canine cancer.  “We are committed to providing resources to the top research teams in the world that can advance our understanding of hemangiosarcoma," said Dr. Kathy Tietje, Chief Program Officer at Morris Animal Foundation. "These innovative research ...

WINSTON-SALEM, NC, September 12, 2023 - When the RegenMed Development Organization (ReMDO) offered its grant opportunity related to regenerative medicine manufacturing and commercialization, the result exceeded expectations. The Regenerative Medicine Manufacturing grant call encouraged small, medium, and large companies to submit letters of interest with an accompanying white paper that addressed a gap in technical capabilities for one or more of the following topic areas: Cell and Biomaterial Manufacturing, Standards and Quality Control, Additive Manufacturing and Artificial Intelligence (AI) and Automation. The grant opportunity will ...

A standard chemotherapy drug injures surrounding non-cancer cells, which can then awakens dormant cancer cells and promotes cancer growth, according to a new study publishing September 12th in the open access journal PLOS Biology by Ramya Ganesan of Emory University, US, and colleagues. The finding is important for understanding cancer recurrence and may point to important new targets to prevent it. Advances in cancer treatment, including chemotherapy, have dramatically reduced mortality for many types of cancer, including breast cancer. Nonetheless, up to 23% of breast cancer patients experience recurrence within the first five years. Treatment is meant to kill all cancer cells, ...

Growing several plant varieties in the same field for disease resistance is a longstanding agricultural practice, but can have unpredictable results. A study publishing September 12th in the open access journal PLOS Biology by Jean-Benoit Morel at Institut National de Recherche pour l'Agriculture l'Alimentation et l'Environnement, Montpellier, France, and colleagues suggests that plant-to-plant interactions may confer disease immunity in both wheat and rice. Neighbor-Modulated Susceptibility (NMS) occurs when healthy, same-species ...

A University of Massachusetts Amherst resource economist finds mandated in-school Body Mass Index (BMI) assessments adopted in varying forms by 24 states to combat childhood obesity have the potential to improve the health of some students while introducing body-image issues for others. The research is believed to be the first to assess these policies as a whole, rather than in single states or school districts. “In states that passed these laws, overweight and obese teens were more likely to correctly describe their bodies as such, compared to states ...

In a significant collaboration, UNIST and the University of Ulsan College of Medicine (hereinafter ‘U of U College of Medicine’) have successfully developed a joint curriculum aimed at cultivating professionals with interdisciplinary expertise. This unique program seeks to bridge the gap between engineering and medicine, producing graduates who possess both medical knowledge and engineering understanding. The collaboration aims to contribute effectively to advancements in healthcare technology and innovation. The jointly developed curriculum consists of seven courses, including ‘Introductions to Medical Science AI‘ and ‘Brain and Cognitive ...

Pneumonia is an infection of the lung alveoli caused by bacteria, viruses or fungi. It is one of the leading causes of morbidity and mortality worldwide, representing a clinical and economic burden and a global public health problem. The microbial ecosystem (or microbiome) of the human respiratory tract colonizes different niches. The respiratory tract microbiome is of interest to scientists as it contributes to human health by stimulating the immune system and protecting against infection by pathogens. Scientists ...

Researchers have developed a non-invasive method for mapping the human auditory pathway, which could potentially be used as a tool to help clinicians decide the best surgical strategy for patients with profound hearing loss. The findings, published today in eLife, highlight the importance of early interventions to give patients the ability to hear and understand speech, so that their auditory-language network can develop properly and their long-term outcomes are improved.  Sensorineural hearing loss (SNHL) occurs when the sensitive hair cells inside the cochlea are damaged, or when there is damage to the auditory nerve which transmits sound to the brain. A person with profound hearing ...

Earlier this year, in a pilot project, the teams of high-tech startup Knowledge Pixels and open-access scholarly publisher and technology provider Pensoft released a novel workflow to publicly share and future-proof scientific findings by means of nanopublications. Nanopublications complement human-created narratives of scientific knowledge with elementary, machine-actionable, simple and straightforward scientific statements that prompt sharing, finding, accessibility, citability and interoperability. By making it easier to trace individual findings back to their origin and/or follow-up updates, it also helps to better understand the provenance of biodiversity ...

September 12, 2023 – As researchers increasingly recognize that causes for health issues are structural and interrelated, real-world, innovative case studies demonstrate the value of applying systems science to evaluate health interventions and address health inequities as seen in a special supplement, supported by the W.K. Kellogg Foundation, in the October/December issue of Family & Community Health. The journal is published in the Lippincott portfolio by Wolters Kluwer.   Systems science offers an effective paradigm for examining and addressing various health issues to improve outcomes and reduce health inequities. The case ...

Philadelphia, September 12, 2023 – Obsessive-compulsive disorder (OCD) is a neurological disorder characterized by repeated behaviors such as cleaning and checking despite clear objective evidence of cleanliness, orderliness, and correctness. Although the disease is often mischaracterized as a disorder of “fussiness,” the disorder actually stems from difficulty in processing uncertainty. However, the neural underpinnings of that aberrant processing remains unknown. Now, a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, uses brain imaging to get a closer look at the underpinnings of uncertainty processing ...

The Association for Psychological Science (APS) has awarded the 2024 APS Lifetime Achievement Awards to 15 psychological scientists whose contributions have advanced understanding of topics ranging from how to alleviate human suffering to cultural differences and similarities in mental processes. APS’s four lifetime achievement awards—the APS James McKeen Cattell Fellow Award, the APS Mentor Award, the APS William James Fellow Award, and the APS James S. Jackson Lifetime Achievement Award for Transformative Scholarship—are the association’s highest honors, and their recipients are among the field’s most accomplished and respected ...

September 12, 2023—(BRONX, NY)—The newly renamed Montefiore Einstein Comprehensive Cancer Center (MECCC) has been awarded comprehensive designation by the National Cancer Institute (NCI) of the National Institutes of Health, the ultimate standard achieved by only 55 other NCI cancer centers in the U.S. Through NCI’s peer-review process, MECCC was nationally recognized for its paradigm-shifting, practice-changing, policy-impacting cancer-focused science. As a result, MECCC was awarded a five-year, $20 million Cancer Center Support Grant to advance the translation of novel cancer research into new treatments, new screening and diagnostic tools, and equitable access ...