About The Study: Among people with insulin-naive type 2 diabetes, once-weekly icodec demonstrated superior HbA1c reduction to once-daily degludec after 26 weeks of treatment, with no difference in weight change and a higher rate of combined level two or three hypoglycemic events in the context of less than one event per patient-year exposure in both groups.  Authors: Ildiko Lingvay, M.D., of the University of Texas Southwestern Medical Center in Dallas, and Yiming Mu, M.D., of the Chinese People’s Liberation Army General Hospital in Beijing, are the corresponding authors. To ...

About The Study: The findings of this study suggest that treatment with bempedoic acid in high-risk primary prevention patients unable to tolerate recommended doses of statins has the potential to reduce major adverse cardiovascular events.  Authors: Steven E. Nissen, M.D., of the Cleveland Clinic, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2023.9696) Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and ...

The policy, which expired at the end of 2021, has not been renewed due to concerns among legislators over the credit being overly generous, particularly to lower-income families with limited tax liability, and the lack of an associated work requirement. The findings, to be published June 24 in JAMA Health Forum, could inform the debate over the policy’s future, said Dr. Jordan Rook, a fellow in the National Clinician Scholars Program at UCLA and the study’s lead author. “Cash transfer programs like the 2021 Child Tax Credit expansion may be powerful tools in improving ...

About The Study: The results of this study suggest that the COVID 19–era policy of Expanded Child Tax Credit monthly payments was associated with improved adult overall health and food security. Cash transfer programs may be effective tools in improving adult health and household nutrition.  Authors: Jordan M. Rook, M.D., of the University of California, Los Angeles, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamahealthforum.2023.1672) Editor’s ...

Edinburgh, UK – 24 June 2023:  Patients who feel low when having a cardiac device implanted are more likely to stop taking their heart medications than those without depression, according to research presented today at ACNAP 2023, a scientific congress of the European Society of Cardiology (ESC).1 Study author Mr. Ole Skov, a psychologist and PhD student in cardiac psychology at the University of Southern Denmark, Odense, Denmark said: “Medications help to control symptoms and prevent further heart problems so adherence is important. Patients with an implantable cardioverter defibrillator (ICD) ...

Alexandria, VA, USA – A diagnostic study on the detection of occlusal caries from a clinical photograph using a deep learning algorithm will be presented at the 101st General Session of the IADR, which will be held in conjunction with the 9th Meeting of the Latin American Region and the 12th World Congress on Preventive Dentistry on June 21-24, 2023, in Bogotá, Colombia. The Interactive Talk presentation, “Automated Detection of Occlusal Caries Using Deep Learning Algorithm,” will take place on Saturday, June 24 at 4:25 p.m. Colombia Time (UTC-05:00) during the “Prevalence ...

RICHLAND, Wash.— From densely built urban cores to sprawling suburbia, cities are complex. This complexity can lead to temperature hot spots within cities, with some neighborhoods (and their residents) facing more heat than others. Understanding this environmental disparity forms the spirit of new research led by scientists at the Department of Energy’s Pacific Northwest National Laboratory. In a new paper examining all major cities in the U.S., the authors find that the average Black resident is exposed to air that is warmer by 0.28 degrees ...

DURHAM, N.C. -- Warmer temperatures are known to make more turtle eggs become female hatchlings, but new research out of Duke University shows that those females also have a higher capacity for egg production, even before their sex is set. This finding may explain why many animals besides turtles have temperature-dependent sex determination and why the system persists, despite seeming like a risky strategy. It may also provide a troubling glimpse of what could lie ahead in a warming world. What the ...

BIRMINGHAM, Ala. – Stress during adolescence can cause postpartum behavioral changes in women and other mammals, including depression and changes in social behavior after the birth of a child. However, the neural circuit mechanisms by which adolescent stress leads to later changes in postpartum social behavior are unclear. In a Nature Communications study, University of Alabama at Birmingham researcher Minae Niwa, Ph.D., used a mouse model and cutting-edge neurobiological techniques to show how psychological stress during adolescence alters neuronal functions in the brain, resulting in altered postpartum social behavior. This ...

Some firearm owners may not want researchers to know they own firearms, according to a study by the New Jersey Gun Violence Research Center at Rutgers. In a study published in Social Psychiatry and Psychiatric Epidemiology, researchers found that based on their answers to a variety of other questions, a group of individuals appeared as though they might be falsely denying firearm ownership when directly asked by researchers. While some of these individuals resemble what previous research indicated to be a typical American firearm owner (e.g., white, male), others looked quite different (racial or ethnic minority, female, ...

NEW YORK, NY--The cause of a common kidney disease likely lies outside the kidney, according to a new study led by Columbia University researchers. The study, which uncovered 16 new locations in the genome linked to immunoglobulin A (IgA) nephropathy, confirms an earlier hypothesis that the immune system has an important role in driving the disease and points toward new strategies for detecting and treating it. No targeted treatments have been approved to treat IgA nephropathy, largely because the underlying cause of the disease has not been well understood. Identifying genes linked ...

Scientists at Stanford Medicine conducted a study describing a new category of depression — labeled the cognitive biotype — which accounts for 27% of depressed patients and is not effectively treated by commonly prescribed antidepressants. Cognitive tasks showed that these patients have difficulty with the ability to plan ahead, display self-control, sustain focus despite distractions and suppress inappropriate behavior; imaging showed decreased activity in two brain regions responsible for those tasks. Because depression has traditionally been defined as a mood disorder, ...

Stanford University’s Innovative Medicines Accelerator (IMA) and Intonation Research Laboratories (Intonation) have formed a collaboration to develop treatments that target cancerous neuroendocrine tumors, or tumors that form from hormone-releasing cells.  The goal of the collaboration is to reduce the time and resources it takes to translate a biomedical breakthrough into a clinically and commercially viable medicine.  “I’m excited about this collaboration with Intonation Research Laboratories, which has the potential to speed ...

The Bachman’s warbler, a songbird that was last seen in North America nearly 40 years ago, was a distinct species and not a hybrid of its two living sister species, according a new study in which the full genomes of seven museum specimens of the bird were sequenced. Genome comparisons of Bachman’s warbler with the golden-winged and blue-winged warblers also helped researchers identify a new candidate gene involved in feather pigmentation in the group. A paper describing the study, led by Penn State researchers, highlights the crucial role that museum collections can play in science and appears ...

WACO, Texas (June 23, 2023) – Women represent the fastest-growing population in U.S. institutional corrections facilities. In the past four decades, the number of women incarcerated has increased by more than 475%, rising from 26,326 in 1980 to 152,854 in 2020.Because the majority of imprisoned women are mothers, a conservative estimate indicates that at least one million American children have experienced maternal incarceration, and a substantial portion of them are adolescents. Evidence suggests that maternal incarceration is a risk factor for adolescents’ ...

A layperson might think of “frail” as simply a synonym for “weak” or “fragile.” But in the medical field, frailty is a specific term, meaning – due to factors including inflammation and hormone shifts – a patient has a lack of physiological reserve, or a reduced ability to tolerate stress. “That stress can be anything from the simple event of falling to getting COVID or another infectious disease,” said Nima Toosizadeh, assistant professor of biomedical engineering and medicine. “Or, it can be a treatment that might be invasive for patients. Knowing who can tolerate the stress is critical.” It ...

“Approaches targeted to prevent this post-therapy cancer cell repopulation should be uncovered to prevent tumor relapse and thus increase overall survival from this devastating disease.” BUFFALO, NY- June 23, 2023 – A new research perspective was published in Oncoscience (Volume 10) on June 1, 2023, entitled, “Cancer cell repopulation after therapy: which is the mechanism?” The past two decades have brought great progress in the treatment of cancer as patients with the disease live ...

Mario Romero-Ortega was selected through a nationwide search to head the University of Arizona Department of Biomedical Engineering, beginning with the fall 2023 semester. “I was drawn by the culture of collaboration, the quality of the students and faculty, and by the unified vision from University of Arizona leadership to impact biomedical engineering and health, from local to global,” he said. Romero-Ortega will join the College of Engineering from the University of Houston, where he serves in the College of Engineering as a Cullen ...

Kyle Emich, a professor of management at the Alfred Lerner College of Business and Economics, along with Rachel Amey and Chad Forbes, then with UD’s Psychology and Brain Sciences Department, were searching for clues about why women’s knowledge often gets ignored in the workplace and how to improve the situation.  Drawing on both a problem-solving group exercise and measurements of brain activity, their findings, now published by the journal Small Group Research, illustrate ways stereotypes and attitudes can ...

The El Gigante rockshelter in western Honduras is among only a handful of archaeological sites in the Americas that contain well-preserved botanical remains spanning the last 11,000 years. Considered one of the most important archaeological sites discovered in Central America in the last 40 years, El Gigante was recently nominated as a UNESCO World Heritage site. “No other location shows, as clearly as El Gigante,” state UNESCO materials about the site’s universal value, “the dynamic character of hunter-gatherer societies, and their adaptive way of life in the Central ...

Water is an essential and indispensable component of humanity’s everyday existence. As the global population grows and the climate warms, so does the water demand.  Over the past two decades, global reservoirs have become increasingly empty despite an overall increase in total storage capacity due to the construction of new reservoirs. Led by Dr. Huilin Gao, associate professor in the Zachry Department of Civil and Environmental Engineering at Texas A&M University, researchers used a new approach with satellite data to estimate the storage variations ...

B cells are thought to play a critical role in innate and adaptive immunity, but their exact role in anti-tumor immunity remains unknown. Researchers at Brigham and Women’s Hospital with expertise in immunology collaborated with experts in dermatology from Massachusetts General Hospital to further understand the role of B cells and identify a subset of cells that may play a critical role. In collaboration with the Broad Institute they used a technique called single-cell profiling, which allows them to look at all the genes ...

NEW YORK & SAN FRANCISCO – June 23, 2023 – Building on the resounding success of last year’s standing-room-only debut, the Cardiovascular Research Foundation (CRF) and Fogarty Innovation are proud to present an even more dynamic and comprehensive TCT MedTech Innovation Forum in 2023. The highly anticipated program will feature additional learning tracks, expanded networking opportunities, increased attendee capacity, and the TCT Shark Tank Innovation Competition. The day-long interactive summit will take place on the first day of TCT 2023 (Transcatheter Cardiovascular Therapeutics), ...

Key takeaways: A new study suggests global future economic growth will be slower than predicted, with developing nations taking longer to close the wealth gap and approach the income of wealthier nations Governments need to start planning for slower-growth scenarios, which may involve wealthier nations providing lower-income countries with financing for climate change adaptations  National debt and debt-ceiling talks may become more contentious in the coming decades  The global economy will grow slower in the 21st century ...

A nascent literature is emerging that analyzes the case of Colin Kaepernick who was “locked out” of the National Football League (NFL) beginning in 2017 because he chose to protest police brutality, systemic racism, and white supremacy. Using status expectations states theory and prototypicality theory, this research re-conceptualizes Kaepernick’s lock-out as an infringement on his right to work. First, researchers utilize a modified case-study approach comparing his experiences to those of six other Black male athletes who were “locked out.” Second, researchers utilize data and “matched cases” to demonstrate empirically ...