Abstract 803: Impact of social isolation and quarantine on the course of diabetes mellitus and its complications during Covid 19 pandemic in Adjara Region Country of Georgia Abstract 1337: Psychological distress in patients with hypocortisolism during mass quarantine for Covid-19 epidemic in Italy Studies reveal that social isolation and quarantine throughout the COVID-19 pandemic may have a detrimental impact on people living with pre-existing conditions. Social isolation and quarantine can have a detrimental impact on physical and mental health of people living with pre-existing conditions, according to two studies being presented ...

Tobacco use continues to be a primary contributor to the global burden of disease, causing an estimated 12% of deaths worldwide among people aged 30 and over. Four leading cardiovascular organizations - American Heart Association, American College of Cardiology, European Society of Cardiology and World Heart Federation - today released a joint opinion calling for greater action at the global scale to end the tobacco epidemic once and for all. The organizations are urging governments to take immediate action to implement the World Health Organization's MPOWER framework, which outlines six essential policy approaches proven to reduce tobacco use: Monitor tobacco use and prevention policies; Protect people from tobacco smoke; Offer help to quit tobacco use; Warn about the dangers ...

COLUMBUS, Ohio - Time not only flies when you're having fun - sometimes anticipating a fun event makes it feel like it will be over as soon as it begins, a new study suggests. Researchers found that people judge future positive events as being both farther away as well as shorter in duration than negative or neutral events. Combining those two elements has a strange effect when people look forward to a positive event like a vacation, said Selin Malkoc, co-author of the study and associate professor of marketing at The Ohio State University's Fisher College of Business. "The seemingly endless wait for the vacation ...

SAN RAMON, Calif., May 26, 2021--A new paper that has been accepted for publication in Ophthalmic & Physiological Optics, the peer-reviewed journal of The College of Optometrists (UK), furthers understanding of myopia control efficacy in the context of normal childhood eye growth. Axial Length Targets for Myopia Control (Chamberlain P, et al.) is now available online via END ...

REYKJAVIK, Iceland 26 May 2021 - Current vaccination programmes alone will have a limited effect in stopping the second wave of COVID infections in the US, according to a study conducted by scientists from Reykjavik University, University of Lyon, University of Southern Denmark and University of Naples Federico II, and published in the Nature Group journal Scientific Reports today. The findings suggest that strict social distancing and other non-pharmaceutical methods are still necessary to end the ongoing second wave in the US and prevent a new one from rising. The study fed real-world data on human mobility into a mathematical model previously used to predict the second wave of ...

Researchers have successfully detected the environmental DNA (eDNA *1) of the Argentine ant (*2) in surface soil samples from sites on Kobe's Port Island and in Kyoto's Fushimi District, two areas that have a long history of destruction caused by this invasive species. The research group included then graduate student YASASHIMOTO Tetsu and Associate Professor MINAMOTO Toshifumi of Kobe University's Graduate School of Human Development and Environment, Visiting Professor OZAKI Mamiko of the Graduate School of Engineering, and NAKAJIMA Satoko, formally of the Kyoto Prefectural Institute of Public Health and Environment. This method can be used to enable scientists ...

A newly released scientific paper in Nature Publishing's Scientific Reports Journal has revealed unprecedented amounts of highly toxic mercury are deposited in the deepest trenches of the Pacific Ocean. The study, a multi-national effort involving scientists from Denmark, Canada, Germany and Japan, reports the first-ever direct measurements of mercury deposition into one of the logistically most challenging environments to sample on Earth, and the deepest at eight to 10 kilometers under the sea. Lead author Professor Hamed Sanei, Director of the Lithospheric Organic Carbon Laboratory (LOC) at the Department of Geoscience, ...

What information is retained in a memory over time, and which parts get lost? These questions have led to many scientific theories over the years, and now a team of researchers at the Universities of Glasgow and Birmingham have been able to provide some answers. Their new study, which is published today in Nature Communications, demonstrates that our memories become less vibrant and detailed over time, with only the central gist eventually preserved. Moreover, this 'gistification' of our memories is boosted when we frequently recall our recent experiences. The work could have implications in a number of areas, including the nature of memories in post-traumatic stress disorder, the repeated questioning ...

The biological clock is present in almost all cells of an organism. As more and more evidence emerges that clocks in certain organs could be out of sync, there is a need to investigate and reset these clocks locally. Scientists from the Netherlands and Japan introduced a light-controlled on/off switch to a kinase inhibitor, which affects clock function. This gives them control of the biological clock in cultured cells and explanted tissue. They published their results on 26 May in Nature Communications. Life on Earth has evolved under a 24-hour cycle; of light and dark, hot and cold. 'As a result, our cells are synchronized to these 24-hour oscillations,' says Wiktor Szymanski, Professor of Radiological Chemistry at the University ...

CLEVELAND, Ohio (May 26, 2021)--Carpal tunnel syndrome (CTS), which causes tingling and numbness in the hand, more commonly affects women than men and tends to peak around the age of menopause. A new study suggests the risk of severe CTS increases in women who underwent bilateral oophorectomy before menopause, and estrogen therapy didn't provide a protective effect. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS). Carpal tunnel syndrome is the most common nerve disorder in the upper body. Although predominately idiopathic in nature, an association with sex hormones has been suggested because of a higher incidence in women ...

Oncotarget published "Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore" which reported that this group previously identified a calcium channel blocker, mibefradil, as a potential GBM radiosensitizer. They discovered that mibefradil selectively inhibits a key DNA repair pathway, alternative non-homologous end joining. Then, they initiated a phase I clinical trial that revealed promising initial efficacy of mibefradil, but further development was hampered by dose-limiting toxicities, including CCB-related cardiotoxicity, off-target hERG channel and cytochrome P450 enzymes interactions. Here, the authors show that mibefradil inhibits ...

Even among a large group of cancer survivors who were mostly insured, college educated and had annual incomes above the national average, up to 10% delayed care in the previous 12 months because they simply could not afford out of pocket expenses like copays and deductibles, investigators report. Being unable to get time off from work and being "nervous" about seeing a health care provider, were among the other frequently cited reasons for not always getting timely survivorship care, investigators at the Medical College of Georgia and Georgia Cancer Center report in the journal Cancer Medicine. Investigators analyzed data from 5,426 cancer survivors who volunteered to share their information with the National Institutes of Health's All of Us Research Program, a historic effort ...

The pandemic has increased older adults' willingness to receive the flu shot, new research shows. The study analyzed survey results of 4,501 Canadians over the age of 50 from ten provinces. Twenty per cent of 1,001 research participants aged 50 to 64 indicated they had not considered getting a flu shot, but were now more likely to given the impact of COVID-19. Of these respondents, 92 per cent inducated that they had not been vaccinated against influenza the year before. Of the 3,500 participants aged 65 and older, eight per cent reported that they had not originally planned to get a flu shot but were now more likely to receive it. "The pandemic has been ...

A hidden planetary crisis has long been neglected that is as serious as the disappearance of species and degradation of habitats. Genetic diversity, which reflects the variation in DNA within species and populations and is the key to their capacity to adapt in times of change, is being lost at an alarming rate. According to an article by 28 authors representing 16 countries, the loss of genetic diversity can affect resiliency in the face of environmental change and result in the loss of important services provided to society. Once gone, genetic diversity can take millennia to return. ...

A new study by Cardiff University in collaboration with the University of Hertfordshire has revealed the huge "secondary burden" placed on those closest to people living with Long Covid. The researchers surveyed more than 700 Covid-19 survivors along with their partners and close relatives to understand for the first time the impact of the disease on families as a whole. The findings, published today in BMJ Open, suggest family quality of life is being "severely affected" and a major system of support is needed for both survivors - and those closest to them. Survivors and their families spoke ...

Clots in the arteries (arterial thrombosis) are the most common cause of stroke (ischaemic stroke) and have been reported in detail for the first time in young adults who received the Oxford-AstraZeneca covid-19 vaccine in a letter from UK stroke specialists published online in Journal of Neurology Neurosurgery & Psychiatry. While rare cases of blood clots have been reported previously after administration of the Oxford-AstraZeneca covid-19 vaccine, these have affected veins and most specifically veins in the brain (cerebral venous sinuses). People who have experienced this unusual form of stroke (cerebral venous sinus thrombosis) have also had low platelet ...

Up to a third of patients taking methotrexate - a common treatment for immune mediated inflammatory conditions such as rheumatoid arthritis and psoriasis/psoriatic arthritis - failed to achieve an adequate immune response to mRNA COVID-19 vaccines in a small study accepted for publication in the journal Annals of Rheumatic Diseases. While mRNA COVID-19 vaccines have been shown to produce an effective immune response in over 90% of healthy adults in clinical trials, it is unknown whether the immune response is as robust in patients with immune-mediated inflammatory diseases (IMID) who may also be taking immunomodulatory medications. The authors assessed the immune response to the mRNA Pfizer-BioNTech COVID-19 vaccine in 82 patients ...

First-born children have a lower risk of cardiovascular events such as heart attacks and strokes than brothers and sisters born later, but people who are part of a large family with many siblings have an increased risk of these events, suggests the results of a large population study in Sweden, published in the online journal BMJ Open. It is well-known that family history - the health of parents and grandparents - has an impact on a person's health, including their risk of cardiovascular events, but now there is growing interest in what influence the make-up of a person's immediate family - the number and age of siblings - might have. The authors accessed data on 1.36 million men and 1.32 million women born between 1932 and 1960 and aged 30-58 years in ...

While some studies suggest female patients treated by female physicians have better outcomes, there does not appear to be a relationship between operator and patient gender and outcome in patients undergoing coronary angioplasty or stenting. These are the results of a first-of-its-kind study by the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) and published in Catheterizations and Cardiovascular Interventions. The study looked at procedures performed by 385 male interventional cardiologists, and 18 female interventional cardiologists at 48 non-federal hospitals across the state of Michigan. Female interventional cardiologists continue to be markedly under-represented and only perform a small percentage of cases, with women accounting for ...

Army ants form some of the largest insect societies on the planet. They are quite famous in popular culture, most notably from a terrifying scene in Indiana Jones. But they are also ecologically important. They live in very large colonies and consume large amounts of arthropods. And because they eat so much of the other animals around them, they are nomadic and must keep moving in order to not run out of food. Due to their nomadic nature and mass consumption of food, they have a huge impact on arthropod populations throughout tropical rainforests floors. Their mass raids are considered the pinnacle of collective foraging behavior in the animal kingdom. The raids are a coordinated ...

CHAMPAIGN, Ill. -- Advanced microscope technology and cutting-edge geological science are giving new perspectives to an old medical mystery: How do kidney stones form, why are some people more susceptible to them and can they be prevented? In a new paper published in the journal Nature Reviews Urology, researchers from the University of Illinois Urbana-Champaign, Mayo Clinic and other collaborators described the geological nature of kidney stones, outlined the arc of their formation, established a new classification scheme and suggested possible clinical interventions. "The process of kidney stone formation is part of the natural process of the stone formation seen throughout nature," Illinois geology professor ...

Reno, Nev. (May 25, 2021) - After a wildfire, soils in burned areas often become water repellent, leading to increased erosion and flooding after rainfall events - a phenomenon that many scientists have attributed to smoke and heat-induced changes in soil chemistry. But this post-fire water repellency may also be caused by wildfire smoke in the absence of heat, according to a new paper from the Desert Research Institute (DRI) in Nevada. In this pilot study (exploratory research that takes place before a larger-scale study), an interdisciplinary team of scientists led by DRI Associate Research Professor of Atmospheric Science Vera Samburova, Ph.D., exposed samples of clean sand to smoke from burning Jeffrey pine needles and branches ...

Cells are the building blocks of life, present in every living organism. But how similar do you think your cells are to a mouse? A fish? A worm? Comparing cell types in different species across the tree of life can help biologists understand how cell types arose and how they have adapted to the functional needs of different life forms. This has been of increasing interest to evolutionary biologists in recent years because new technology now allows sequencing and identifying all cells throughout whole organisms. "There's essentially a wave in the scientific community to classify all types of cells in a wide variety of different organisms," explained Bo Wang, an assistant professor of bioengineering at Stanford University. In response to this opportunity, ...

A new study finds that fly ash--particles left over from burning coal--make up between 37 and 72 percent of all particulate organic carbon carried by the Yangtze River in China, or around 200,000 to 400,000 tons of carbon per year. The study, which is the first of its kind, shows just how big an impact fossil fuel consumption has on Earth. Beyond pumping carbon dioxide into the atmosphere, coal burning dumps about as much particulate carbon into the Yangtze River as natural processes do. The findings were published in the Proceedings of the National Academy of Sciences (PNAS) on May 17. "About one-fifth of the world's coal consumption occurs along this river," says Gen Li, postdoctoral ...

A new report by Skoltech scientists and their colleagues describes an organic material for the new generation of energy storage devices, which structure follows an elegant molecular design principle. It has recently been published in ACS Applied Energy Materials and made the cover of the journal. While the modern world relies on energy storage devices more and more heavily, it is becoming increasingly important to implement sustainable battery technologies that are friendlier to the environment, are easy to dispose, rely on abundant elements only, and are cheap. Organic batteries are desirable ...