DENVER/January 5, 2020 - Some English bulldogs diagnosed with a common cancer may instead have a newly described, non-cancerous syndrome called polyclonal B‐cell lymphocytosis. The discovery was made by Morris Animal Foundation-funded researchers at Colorado State University during a study to better understand B-cell chronic lymphocytic leukemia (BCLL). The team published their findings in the Journal of Veterinary Internal Medicine. "This could save some dogs from being misdiagnosed, treated for cancer or even euthanized when they shouldn't be," said Dr. Anne Avery, Professor, Department of Microbiology, Immunology and Pathology at Colorado State University. "The dogs may look to their veterinarians like they ...

BOSTON - (January 4, 2021) - As they age, people with diabetes are more likely to develop Alzheimer's disease and other cognitive disorders than are people without diabetes. Scientists at Joslin Diabetes Center now have shown that routine eye imaging can identify changes in the retina that may be associated with cognitive disorders in older people with type 1 diabetes. These results may open up a relatively easy method for early detection of cognitive decline in this population, providing better ways to understand, diagnose and ultimately treat the decline, said George L. King, MD, Joslin's Chief Scientific Officer and senior author on a paper about the study in the Journal of Clinical Endocrinology & Metabolism. Previous research had demonstrated an association ...

To stop biodiversity loss, Canada recently committed to protecting 30% of its land and sea by 2030. But making conservation decisions about where to locate new protected areas is complicated. It depends on data both about biodiversity and about a range of benefits (e.g. freshwater, climate regulation, recreation) that people get from nature. Surprisingly, despite the size of the country, new mapping suggests that less than 1% of Canada's land (0.6% of total area or approximately 56,000 km2) is a hot spot, providing all these benefits in one place. Moreover, the study published today in Environmental Research Letters suggests that some of the most critical areas where people receive these key benefits from ...

Leipzig. The transition from the Medieval Warm Period to the Little Ice Age was apparently accompanied by severe droughts between 1302 and 1307 in Europe; this preceded the wet and cold phase of the 1310s and the resulting great famine of 1315-21. In the journal Climate of the Past, researchers from the Leibniz Institutes for the History and Culture of Eastern Europe (GWZO) and Tropospheric Research (TROPOS) write that the 1302-07 weather patterns display similarities to the 2018 weather anomaly, in which continental Europe experienced exceptional heat and drought. Both the medieval and recent weather patterns resemble the stable weather patterns that have occurred more frequently since the 1980s due to the increased warming of the Arctic. ...

A clear view of anatomical structures is vital for the success of surgery--especially in microsurgery where narrow anatomical cavities or proximity to vulnerable organs and tissues can pose significant risks to patient health. The surgical microscope has evolved to become a powerful tool for improving surgical visualization. A END ...

TROY, N.Y. -- A loss of enzymatic processes within the body can increase a person's risk of bone fracture. This new insight was recently published in eLife by an international team of scientists and engineers led by Deepak Vashishth, the director of the Center for Biotechnology and Interdisciplinary Studies (CBIS) at Rensselaer Polytechnic Institute. Enzymatic processes are essential to any number of chemical reactions that occur within the body, including the production of the extracellular matrix within bone that is critical for mechanical support. Phosphorylation -- one of those key enzymatic processes -- is the attachment of a phosphoryl to a protein, and is critical for ...

Worldwide, marine megafauna are at risk of extinction due to climate change, habitat loss, pollution, overhunting, population fragmentation, and hybridization with related species in areas disturbed by humans. Genetic studies can help determine the conservation status of marine animals, identifying threats to species conservation and informing interventions and policies, such as the protection of diversity hotspots or corridors for gene flow. In a new study in Frontiers in Marine Science, researchers for the first time measured genetic diversity in manatees ...

CHAMPAIGN, Ill. -- A small portion of scientific papers are retracted for research that is in error or fraudulent. But those papers can continue to be cited by other scientists in their work, potentially passing along the misinformation from the retracted articles. Jodi Schneider, a professor of information sciences at the University of Illinois Urbana-Champaign who studies scholarly publications and how information gets used, is considering how scientific journals can better communicate about retracted articles. In a new study published in the ...

Most of the mangrove forests on the coasts of Oman disappeared about 6,000 years ago. Until now, the reason for this was not entirely clear. A current study of the University of Bonn (Germany) now sheds light on this: It indicates that the collapse of coastal ecosystems was caused by climatic changes. In contrast, falling sea level or overuse by humans are not likely to be the reasons. The speed of the mangrove extinction was dramatic: Many of the stocks were irreversibly lost within a few decades. The results are published in the journal Quaternary Research. Mangroves are trees that occupy a very special ecological niche: They grow in the so-called tidal range, meaning coastal areas that are ...

ALBUQUERQUE, N.M. -- If everything moved 40,000 times faster, you could eat a fresh tomato three minutes after planting a seed. You could fly from New York to L.A. in half a second. And you'd have waited in line at airport security for that flight for 30 milliseconds. Thanks to machine learning, designing materials for new, advanced technologies could accelerate that much. A research team at Sandia National Laboratories has successfully used machine learning -- computer algorithms that improve themselves by learning patterns in data -- to complete cumbersome materials science calculations more than 40,000 times faster than normal. Their results, published Jan. 4 in END ...

Australian research has identified a new mechanism in which prostate cancer cells can 'switch' character and become resistant to therapy. These findings, just published in Cell Reports, are an important development in unravelling how an aggressive subtype of prostate cancer, neuroendocrine prostate cancer (NEPC), develops after hormonal therapies. It is well established that some tumours show increased cellular 'plasticity' in response to new or stressful conditions, such as cancer therapy, says lead researcher Associate Professor Luke Selth, from the Flinders ...

What The Study Did: Data from public health surveillance of reported COVID-19 cases and seroprevalence surveys were used in this observational study that reports an estimated 46.9 million SARS-CoV-2 infections, 28.1 million symptomatic infections, 956,174 hospitalizations and 304,915 deaths occurred in the U.S. through November 15, 2020. Authors: Frederick J. Angulo, D.V.M., Ph.D., of  Medical Development and Scientific/Clinical Affairs of Pfizer Vaccines, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2020.33706) Editor's ...

A new study led by researchers at the Universities of Bristol, Exeter, and Bath helps to shed light on the winter weather we may soon have in store following a dramatic meteorological event currently unfolding high above the North Pole. Weather forecasting models are predicting with increasing confidence that a sudden stratospheric warming (SSW) event will take place today, 5 January 2021. The stratosphere is the layer of the atmosphere from around 10-50km above the earth's surface. SSW events are some of the most extreme of atmospheric phenomena and can see polar stratospheric temperature increase by up to 50°C over the course of a few days. Such events ...

By André Julião  |  Agência FAPESP - The black lion tamarin (Leontopithecus chrysopygus) once inhabited most forest areas in the state of São Paulo, Southeast Brazil, but currently occupies only some Atlantic Rainforest remnants there. In recent years, after various studies of the endangered species, environmental NGO Instituto de Pesquisas Ecológicas (IPÊ) moved groups of these animals to areas from which the species had disappeared.  Similar initiatives have now been reinforced by a group of researchers at IPÊ, São Paulo State University (UNESP) and the Federal University of Mato Grosso (UFMT), who cross-tabulated climate data and data on landscape (forest cover) to determine the sites best suited for future ...

The asteroid impact 66 million years ago that ushered in a mass extinction and ended the dinosaurs also killed off many of the plants that they relied on for food. Fossil leaf assemblages from Patagonia, Argentina, suggest that vegetation in South America suffered great losses but rebounded quickly, according to an international team of researchers. "Every mass extinction event is like a reset button, and what happens after that reset depends on which organisms survive and how they shape the biosphere," said Elena Stiles, a doctoral student at the University of Washington who completed the research as part of her master's thesis at Penn State. "All the biodiversity ...

PROVIDENCE, R.I. [Brown University] -- Last month, Japan's Hayabusa2 mission brought home a cache of rocks collected from a near-Earth asteroid called Ryugu. While analysis of those returned samples is just getting underway, researchers are using data from the spacecraft's other instruments to reveal new details about the asteroid's past. In a study published in Nature Astronomy, researchers offer an explanation for why Ryugu isn't quite as rich in water-bearing minerals as some other asteroids. The study suggests that the ancient parent body from which Ryugu was formed had likely dried out in some kind of heating event before Ryugu came into being, which left Ryugu itself drier than expected. "One of the ...

Repeated intravenous (IV) ketamine infusions significantly reduce symptom severity in individuals with chronic post-traumatic stress disorder (PTSD) and the improvement is rapid and maintained for several weeks afterwards, according to a study conducted by researchers from the Icahn School of Medicine at Mount Sinai. The study, published September XX in the American Journal of Psychiatry, is the first randomized, controlled trial of repeated ketamine administration for chronic PTSD and suggests this may be a promising treatment for PTSD patients. "Our findings provide insight into the treatment efficacy of repeated ketamine ...

As the world grows increasingly globalized, one of the ways that countries have come to rely on one another is through a more intricate and interconnected food supply chain. Food produced in one country is often consumed in another country -- with technological advances allowing food to be shipped between countries that are increasingly distant from one another. This interconnectedness has its benefits. For instance, if the United States imports food from multiple countries and one of those countries abruptly stops exporting food to the United States, there are still other countries that can be relied on ...

SAN ANTONIO and CHICAGO - An article published Jan. 5 in Alzheimer's & Dementia: The Journal of the Alzheimer's Association cites decades of published scientific evidence to make a compelling case for SARS-CoV-2's expected long-term effects on the brain and nervous system. Dementia researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) are the first and senior authors of the report and are joined by coauthors from the Alzheimer's Association and Nottingham and Leicester universities in England. "Since the flu pandemic of 1917 and 1918, many of the flulike diseases have been associated with brain disorders," said lead author ...

DURHAM, N.C. -- Self-control, the ability to contain one's own thoughts, feelings and behaviors, and to work toward goals with a plan, is one of the personality traits that makes a child ready for school. And, it turns out, ready for life as well. In a large study that has tracked a thousand people from birth through age 45 in New Zealand, researchers have determined that people who had higher levels of self-control as children were aging more slowly than their peers at age 45. Their bodies and brains were healthier and biologically younger. In interviews, the higher self-control group also showed they may be better equipped to handle the health, financial and social challenges of later life as well. The researchers used structured interviews and credit checks ...

NEW YORK, NY (1/5/2021) - Subtle changes in speech and language can be an early warning sign of Alzheimer's -- sometimes appearing long before other more serious symptoms. The challenge is recognizing these changes and determining what may signal Alzheimer's or other neurodegenerative disorders. In a commentary in END ...

One sweaty, huffing, exercising person emits as many chemicals from their body as up to five sedentary people, according to a new University of Colorado Boulder study. And notably, those human emissions, including amino acids from sweat or acetone from breath, chemically combine with bleach cleaners to form new airborne chemicals with unknown impacts to indoor air quality. "Humans are a large source of indoor emissions," said Zachary Finewax, CIRES research scientist and lead author of the new study out in the current edition of Indoor Air. "And chemicals in indoor air, whether from our bodies or cleaning products, don't just disappear, they linger and travel around spaces like gyms, reacting with other chemicals." In 2018, the CU Boulder ...

Heating up cancer cells while targeting them with chemotherapy is a highly effective way of killing them, according to a new study led by UCL researchers. The study, published in the Journal of Materials Chemistry B, found that "loading" a chemotherapy drug on to tiny magnetic particles that can heat up the cancer cells at the same time as delivering the drug to them was up to 34% more effective at destroying the cancer cells than the chemotherapy drug without added heat. The magnetic iron oxide nanoparticles that carry the chemotherapy drug shed heat when exposed to an alternating magnetic field. This means that, once the nanoparticles have accumulated in the tumour area, an alternating magnetic field can be applied from outside the ...

Researchers in Japan have made the first observations of biological magnetoreception - live, unaltered cells responding to a magnetic field in real time. This discovery is a crucial step in understanding how animals from birds to butterflies navigate using Earth's magnetic field and addressing the question of whether weak electromagnetic fields in our environment might affect human health. "The joyous thing about this research is to see that the relationship between the spins of two individual electrons can have a major effect on biology," said Professor Jonathan Woodward from the University of Tokyo, who conducted the research with doctoral ...

Two studies from the University of Copenhagen show that Danes aren't quite as good as Chinese at discerning bitter tastes. The research suggests that this is related to anatomical differences upon the tongues of Danish and Chinese people. For several years, researchers have known that women are generally better than men at tasting bitter flavours. Now, research from the University of Copenhagen suggests that ethnicity may also play a role in how sensitive a person is to the bitter taste found in for example broccoli, Brussels sprouts and dark chocolate. By letting test subjects taste the bitter substance PROP, two studies demonstrate that Danish and Chinese people experience this basic taste differently. The reason seems to be related to an anatomical difference upon ...