TROY, N.Y. -- Blood sample analysis showed that, two to five years after they gave birth, mothers of children with autism spectrum disorder (ASD) had several significantly different metabolite levels compared to mothers of typically developing children. That's according to new research recently published in BMC Pediatrics by a multidisciplinary team from Rensselaer Polytechnic Institute, Arizona State University, and the Mayo Clinic. Researchers analyzed blood samples from 30 mothers whose young children had been diagnosed with ASD and 29 mothers of typically developing children. At the time that the samples were taken, the women's children were between 2 and 5 years old. The team found differences in several metabolite levels between the two groups of mothers. ...

Research led by the University of Wyoming shows that physical weathering is far more important than previously recognized in the breakdown of rock in mountain landscapes. Because it is difficult to measure, physical weathering has commonly been assumed to be negligible in previous studies. Cliff Riebe, a professor in UW's Department of Geology and Geophysics, headed a research group that discovered that climate and erosion rates strongly regulate the relative importance of subsurface physical and chemical weathering of saprolite, the zone of weathered rock that retains the relative positions of mineral grains of the parent bedrock and lies between ...

A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord. The discovery, published in the Journal of Neuroimmunology, could be important in treating or preventing the progression of multiple sclerosis and other central nervous system disorders. The new research in a mouse model advances earlier work to develop the compound - known as sobetirome - that has already showed promise in stimulating the repair of myelin. "Sobetirome and related drugs are effective at stimulating myelin repair after damage has occurred. Our new findings now suggest that these drugs could also prove ...

Earth gets blasted by mild short gamma-ray bursts (GRBs) most days. But sometimes a giant flare like GRB 200415A arrives at our galaxy, sweeping along energy that dwarfs our sun. In fact, the most powerful explosions in the universe are gamma-ray bursts. Now scientists have shown that GRB 200415A came from another possible source for short GRBs. It erupted from a very rare, powerful neutron star called a magnetar. Previous detected GRB's came from relatively far away from our home galaxy the Milky Way. But this one was from much closer to home, in cosmic terms. GRB explosions can disrupt mobile phone reception on earth, but they can also be messengers from ...

(Boston)--What percent of patients with Alzheimer's Disease (AD) currently have severe dementia? Do more people have mild disease? Or are the majority suffering with moderate dementia? A new study using data from the Framingham Heart Study (FHS) sheds light on these trends. Boston University School of Medicine researchers have found that slightly more than half (50.4 percent) of cases are mild, just under one-third (30.3 percent) of cases are moderate and 19.3 percent are severe cases. Among all participants with mild cognitive impairment (MCI) and AD, the pooled percentage was 45.2 percent for the combined group of mild AD dementia and MCI that later ...

In 2007, an increase in world food prices led to a global rush for land in the form of land grabs or large-scale land acquisitions. Over the last two decades, such acquisitions have resulted in millions of hectares of land changing hands in developing nations. Although such changeover can increase the cultivation of crops needed to feed the world's growing population and spark new agricultural practices and technologies, it can also lead to environmental degradation, increased carbon emissions and threats to the livelihoods of smallholder farmers. The socioeconomic ...

Financial responsibility means managing money in a relatively sensible way by minimizing superfluous or unnecessary spending. But according to new research from the University of Notre Dame, people think they are more financially responsible than they actually are. Even when people consistently spend their money superfluously, they still believe that they manage their money in a responsible fashion, according to " END ...

New Rochelle, NY, January 13, 2021--Aggressive video games are not a risk factor for mental health problems, according to a new study of more than 3,000 youth. This study is part of a special issue on the effects of violent video games published in the peer-reviewed journal Cyberpsychology, Behavior, and Social Networking. Click here to read the issue now. Christopher Ferguson, PhD, Stetson University, and C.K. John Wang, PhD, Nanyang Technological University, examined whether early exposure to aggressive games was predictive of anxiety depression, somatic symptoms, or ...

Apart from black holes, magnetars may be the most extreme stars in the universe. With a diameter less than the length of Manhattan, they pack more mass than that of our sun, wield the largest magnetic field of any known object -- more than 10 trillion times stronger than a refrigerator magnet -- and spin on their axes every few seconds. A type of neutron star -- the remnant of a supernova explosion -- magnetars are so highly magnetized that even modest disturbances in the magnetic field can cause bursts of X-rays that last sporadically for weeks or months. These exotic, compact stars are also thought to be the source of some types of short gamma ray bursts (GRBs): bright flashes of highly energetic radiation that have ...

Primary amoebic meningoencephalitis (PAM), a deadly disease caused by the "brain-eating amoeba" Naegleria fowleri, is becoming more common in some areas of the world, and it has no effective treatment. Now, researchers reporting in ACS Chemical Neuroscience have found that a compound isolated from the leaves of a traditional medicinal plant, Inula viscosa or "false yellowhead," kills the amoebae by causing them to commit cell suicide in lab studies, which could lead to new treatments. PAM, characterized by headache, fever, vomiting, hallucinations and seizures, is almost always fatal within a couple of weeks of developing symptoms. Although the disease, which is usually contracted ...

New probes allow scientists to see four-stranded DNA interacting with molecules inside living human cells, unravelling its role in cellular processes. DNA usually forms the classic double helix shape of two strands wound around each other. While DNA can form some more exotic shapes in test tubes, few are seen in real living cells. However, four-stranded DNA, known as G-quadruplex, has recently been seen forming naturally in human cells. Now, in new research published today in Nature Communications, a team led by Imperial College London scientists have created new probes that can see how G-quadruplexes are interacting ...

On April 15, 2020, a brief burst of high-energy light swept through the solar system, triggering instruments on several NASA and European spacecraft. Now, multiple international science teams conclude that the blast came from a supermagnetized stellar remnant known as a magnetar located in a neighboring galaxy. This finding confirms long-held suspicions that some gamma-ray bursts (GRBs) - cosmic eruptions detected in the sky almost daily - are in fact powerful flares from magnetars relatively close to home. "This has always been regarded as a possibility, and several GRBs observed since 2005 have provided tantalizing evidence," said Kevin Hurley, a Senior Space Fellow with the Space Sciences Laboratory at the University of California, Berkeley, ...

While most children need to show immunization records to attend school, the same may not be true for camps, a new study suggests. Nearly half of summer camps surveyed by researchers didn't have official policies requiring campers be vaccinated, according to findings led by Michigan Medicine C.S. Mott Children's Hospital in END ...

KANSAS CITY, MO--What if the degenerative eye conditions that lead to glaucoma, corneal dystrophy, and cataracts could be detected and treated before vision is impaired? Recent findings from the lab of Investigator Ting Xie, PhD, at the Stowers Institute for Medical Research point to the ciliary body as a key to unlocking this possibility. Previous work from the lab showed that when mouse stem cells were differentiated into light-sensing photoreceptor cells in vitro, and then transplanted back into mice with a degenerative condition of the retina, they could partially restore vision. However, the transplanted photoreceptors only lasted three to four months. "You cannot cure the condition in a diseased eye if you don't know what ...

Scientists in China and Sweden have determined that a pinch of capsaicin, the chemical compound that gives chili peppers their spicy sting, may be a secret ingredient for more stable and efficient perovskite solar cells. The research, published January 13 in the journal Joule, determined that sprinkling capsaicin into the precursor of methylammonium lead triiodide (MAPbI3) perovskite during the manufacturing process led to a greater abundance of electrons (instead of empty placeholders) to conduct current at the semiconductor's surface. The addition resulted in polycrystalline MAPbI3 solar cells with the most efficient charge transport to date. "In the future, green and sustainable forest-based biomaterial ...

NEW YORK, January 13, 2021 -- Many animal and insect species use Batesian mimicry -- mimicking a poisonous species -- as a defense against predators. The common palmfly Elymnias hypermnestra -- a species of satyrine butterfly that is found throughout wide areas of tropical and subtropical Asia -- adds a twist to this evolutionary strategy. The females evolved two distinct forms, either orange or dark brown, imitating two separate poisonous model species, Danaus or Euploea. The males are uniformly brown. A population group is either entirely brown (both males and females) or mixed (brown males and orange females). David Lohman, ...

The iconic, prehistoric dire wolf, which prowled through Los Angeles and elsewhere in the Americas over 11 millennia ago, was a distinct species from the slightly smaller gray wolf, an international team of scientists reports today in the journal Nature. The study, which puts to bed a mystery that biologists have pondered for more than 100 years, was led by researchers from UCLA, along with colleagues from Durham University in the U.K., Australia's Adelaide University and Germany's Ludwig Maximilian University. "The terrifying dire wolf, a legendary symbol of Los Angeles and the La Brea Tar Pits, has earned its place among the many large, unique species that went extinct at the end of the Pleistocene ...

Mutations that occur in certain DNA regions, called tandem repeats, may play a significant role in autism spectrum disorders, according to research led by Melissa Gymrek, assistant professor in the UC San Diego Department of Computer Science and Engineering and School of Medicine. The study, which was published in Nature on Jan. 14, was co-authored by UCLA professor of human genetics Kirk Lohmueller and highlights the contributions these understudied mutations can make to disease. "Few researchers really study these repetitive regions because they're generally non-coding--they do not make proteins; their function is ...

Extinct dire wolves split off from other wolves nearly six million years ago and were only a distant relative of today's wolves, according to new research published in Nature today (13 January). Dire wolves, made famous in the TV show Game of Thrones, were common across North America until around 13,000 years ago, after which they went extinct. The study shows that dire wolves were so different from other canine species like coyotes and grey wolves that they were not able to breed with each other. Previous analyses, based on morphology alone, had led scientists to believe that dire wolves were closely related to grey wolves. The research was led by Durham University in the UK alongside scientists at the University of Oxford, Ludwig Maximilian University in ...

New York, NY--January 13, 2021--Researchers at Columbia Engineering report today that they have developed the first nanomaterial that demonstrates "photon avalanching," a process that is unrivaled in its combination of extreme nonlinear optical behavior and efficiency. The realization of photon avalanching in nanoparticle form opens up a host of sought-after applications, from real-time super-resolution optical microscopy, precise temperature and environmental sensing, and infrared light detection, to optical analog-to-digital conversion and quantum sensing. "Nobody has seen avalanching behavior like this in nanomaterials before," said James Schuck, associate professor of mechanical engineering, who led the study published today by Nature. "We ...

Even computers can miscalculate. Already small disturbances change stored information and corrupt results. That is why computers use methods to continuously correct such errors. In quantum computers, the vulnerability to errors can be reduced by storing quantum information in more than a single quantum particle. These logical quantum bits are less sensitive to errors. In recent years, theorists have developed many different error correction codes and optimized them for different tasks. "The most promising codes in quantum error correction are those defined on a two-dimensional lattice," ...

A new study by researchers at the University of Chicago and the City College of New York (CCNY) has identified a unique, genetic "mimicry switch" that determines whether or not male and female Elymnias hypermnestra palmflies mimic the same or different species of butterflies. The results indicate that sexual dimorphism has repeatedly emerged in different palmfly populations, and linked the trait to a gene associated with melanin localization and regulation. Published on Jan. 13 in the journal END ...

Red and green algae that grow on snow in the Antarctic Peninsula (AP) cause significant extra snowmelt on par with melt from dust on snow in the Rocky Mountains, according to a first-of-its-kind scientific research study led by Alia Khan, affiliate research scientist at the National Snow and Ice Data Center (NSIDC) and assistant professor at Western Washington University. Algal blooms are likely to increase in Antarctica as the planet continues to warm, which will further exacerbate seasonal snowmelt and contribute to the expansion of ice-free areas in the AP region. This could have serious impacts on regional climate, snow and ice melt, freshwater availability and ecosystems, yet is not accounted for in current global climate models. Results of the research were published on ...

Scientists claim to have found the 'missing link' in the process that leads to an ice age on Earth. Melting icebergs in the Antarctic are the key, say the team from Cardiff University, triggering a series of chain reactions that plunges Earth into a prolonged period of cold temperatures. The findings have been published today in Nature from an international consortium of scientists from universities around the world. It has long been known that ice age cycles are paced by periodic changes to Earth's orbit of the sun, which subsequently changes the amount of solar radiation that reaches the Earth's surface. However, ...

KU Leuven researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study, carried out in mice and humans, was published in Nature. Up to 20% of the world's population suffers from the irritable bowel syndrome (IBS), which causes stomach pain or severe discomfort after eating. This affects their quality of life. Gluten-free and other diets can provide some relief, but why this works is a mystery, since the patients are not allergic to the foods in question, nor do they ...