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OU professor developing vaccine to protect global communities from malaria

2015-06-29
A University of Oklahoma professor studying malaria mosquito interaction has discovered a new mosquito protein for the development of a new vaccine that is expected to stop the spread of the disease in areas where it is considered endemic. Malaria is transmitted by mosquitoes, and it infects millions of people in Africa, Asia and South America every year, causing a global health crisis. In addition to the local populations, U.S. military personnel stationed in these areas and travelers to these malaria-prone areas are at risk of becoming infected. Jun Li, assistant ...

A deep, dark mystery

A deep, dark mystery
2015-06-29
UC Santa Barbara geologist Jim Boles has found evidence of helium leakage from the Earth's mantle along a 30-mile stretch of the Newport-Inglewood Fault Zone in the Los Angeles Basin. Using samples of casing gas from two dozen oil wells ranging from LA's Westside to Newport Beach in Orange County, Boles discovered that more than one-third of the sites -- some of the deepest ones -- show evidence of high levels of helium-3 (3He). Considered primordial, 3He is a vestige of the Big Bang. Its only terrestrial source is the mantle. Leakage of 3He suggests that the Newport-Inglewood ...

Societies issue recommendations for left atrial appendage occlusion

2015-06-29
WASHINGTON (June 29, 2015) -The American College of Cardiology, Heart Rhythm Society and Society for Cardiovascular Angiography and Interventions today released a new overview on the implantation of left atrial appendage occlusion devices. The implantation of left atrial appendage occlusion devices may lower the risk of stroke in patients with atrial fibrillation. As new devices are developed, it is anticipated that the use of left atrial appendage occlusion technologies in clinical practice will expand. The authors of the paper urge that the new technology should be ...

Key element of human language discovered in bird babble

2015-06-29
Stringing together meaningless sounds to create meaningful signals was previously thought to be the preserve of humans alone, but a new study, publishing June 29th in the Open Access journal PLOS Biology, has revealed that babbler birds are also able to communicate in this way. Researchers at the Universities of Exeter and Zurich discovered that the chestnut-crowned babbler - a highly social bird found in the Australian Outback - has the ability to convey new meaning by rearranging the meaningless sounds in its calls. This babbler bird communication is reminiscent of ...

Cranberry juice may help protect against heart disease and diabetes risk factors

2015-06-29
LAKEVILLE-MIDDLEBORO, Mass., (June 29, 2015) - A new study (1) reveals that drinking low-calorie cranberry juice cocktail may help lower the risk of chronic diseases that rank among the leading causes of death worldwide, including heart disease, diabetes and stroke. The finding is welcome news considering the World Health Organization estimates the trio of diseases annually claim 15.6 million lives around the globe (2). These illnesses are among the most common and costly health conditions, but fortunately, they are also among the most preventable through dietary intervention. ...

Experts cover MERS outbreak in American Journal of Respiratory and Critical Care Medicine

2015-06-29
An overview and analysis of the factors underlying the recent Middle East Respiratory Syndrome coronavirus (MERS-CoV) outbreak in Korea has been published online ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. "On 20 May 2015, the Republic of Korea confirmed the first case of MERS-CoV infection in a 68 year old male who had returned to Seoul after traveling to 4 countries in the Middle East," write co-authors David S Hui, MD, of the Chinese University of Hong Kong, and Malik Peiris, DPhil, of the University ...

Athletes should drink only when thirsty, according to new guidelines

2015-06-29
MAYWOOD, Ill. - At least 14 deaths of marathon runners, football players and other athletes have been attributed to a condition called exercise-associated hyponatremia, which results from drinking too much water or sports drinks. But there's an easy way to prevent hyponatremia, according to new guidelines from an international expert panel: Simply put, drink only when you're thirsty. "Using the innate thirst mechanism to guide fluid consumption is a strategy that should limit drinking in excess and developing hyponatremia while providing sufficient fluid to prevent ...

Mayo Clinic study suggests which glioblastoma patients may benefit from drug treatment

2015-06-29
JACKSONVILLE, Fla. -- Clinicians testing the drug dasatinib, approved for several blood cancers, had hoped it would slow the aggressive growth of the deadly brain cancer glioblastoma; however, clinical trials to date have not found any benefit. Researchers at Mayo Clinic, who conducted one of those clinical trials, believe they know why dasatinib failed -- and what to do about it. In the online issue of Molecular Oncology, investigators report finding that dasatinib inhibits proteins that promote cancer growth as expected but also suppresses proteins that protect against ...

When times are tough, parents favor daughters over sons

2015-06-29
In tough economic times, parents financially favor daughters over sons, according to researchers at the Carlson School of Management and Rutgers Business School. Their study, forthcoming in the Journal of Consumer Research, found participants preferred to enroll a daughter rather than a son in beneficial programs, preferred to give a U.S. Treasury bond to a daughter rather than a son, and bequeathed a greater share of their assets to female offspring in their will when they perceived economic conditions to be poor. "Almost all parents say that they don't favor one of ...

Specialized therapy can aid traumatized children in developing nations

2015-06-29
A specific type of talk therapy dispensed in the developing world to orphans and other vulnerable children who experienced trauma such as sexual and domestic abuse showed dramatic results, despite being administered by workers with little education, new research shows. The findings, from a group of researchers led by the Johns Hopkins Bloomberg School of Public Health, suggest that young people from poor nations can benefit from mental health treatment, even when health professionals do not provide it. Untreated childhood trauma, the researchers say, is linked to skills ...

Upsetting a fragile alliance triggers a deadly childhood disease

2015-06-29
Scientists at the University of Malta and the Institut de Génétique Moléculaire de Montpellier (CNRS/Université de Montpellier) have shown that fruit flies and brewer's yeast can reveal clues about the cause of Spinal Muscular Atrophy (SMA), the most common genetic killer of infants. SMA is a devastating neuromuscular disorder that robs children of their ability to walk, eat, or breathe. Mostly caused by an inherited flaw in the Survival Motor Neuron (SMN) gene, SMA is presently without a cure. A key reason is the lack of detailed information on how ...

Flatworms could replace mammals for some toxicology tests

2015-06-29
Laboratories that test chemicals for neurological toxicity could reduce their use of laboratory mice and rats by replacing these animal models with tiny aquatic flatworms known as freshwater planarians. Scientists at UC San Diego have discovered that planarians, commonly used in high-school biology labs to study regeneration and the primitive nervous system, are actually quite sophisticated when it comes to modeling the response of the developing human nervous system to potentially toxic chemicals. The researchers published their findings in the current issue of the journal ...

Tamper-resistant opioids will not solve opioid addiction problem

2015-06-29
Tamper-resistant formulations of drugs will not solve the problems of opioid addiction and overdose, argues a commentary in CMAJ (Canadian Medical Association Journal). Governments in Canada and the United States are promoting tamper-resistant drugs, which are more difficult to crush, snort or inject, to prevent addiction and other harms. Opioid users may tamper with prescribed tablets, capsules or patches for a faster "high." "Misuse and diversion of opioids is a complex problem that requires a comprehensive solution; simply substituting one formulation for another ...

Automatic bug repair

2015-06-29
At the Association for Computing Machinery's Programming Language Design and Implementation this month, MIT researchers presented a new system that repairs dangerous software bugs by automatically importing functionality from other, more secure applications. Remarkably, the system, dubbed CodePhage, doesn't require access to the source code of the applications whose functionality it's borrowing. Instead, it analyzes the applications' execution and characterizes the types of security checks they perform. As a consequence, it can import checks from applications written ...

New IOM report: Wait times for health care services differ greatly throughout US

2015-06-29
WASHINGTON - Tremendous variability in wait times for health care appointments exists throughout the U.S., ranging from same day service to several months, says a new report from the Institute of Medicine. However, there is currently an opportunity to develop "systems-based approaches" -- similar to systems-based engineering approaches applied successfully in industries beyond health care -- that aim to provide immediate engagement of a patient's concern at the point of initial contact and can be used in in-person appointments as well as alternatives such as team-based ...

New nanogenerator harvests power from rolling tires

New nanogenerator harvests power from rolling tires
2015-06-29
MADISON - A group of University of Wisconsin-Madison engineers and a collaborator from China have developed a nanogenerator that harvests energy from a car's rolling tire friction. An innovative method of reusing energy, the nanogenerator ultimately could provide automobile manufacturers a new way to squeeze greater efficiency out of their vehicles. The researchers reported their development, which is the first of its kind, in a paper published May 6, 2015, in the journal Nano Energy. Xudong Wang, the Harvey D. Spangler fellow and an associate professor of materials ...

Scientists develop more accurate whole genome variant discovery and interpretation

2015-06-29
NEW YORK -- June 29, 2015 /Press Release/ -- Scientists from the Icahn School of Medicine at Mount Sinai have developed a new approach to build nearly complete genomes by combining high-throughput DNA sequencing with genome mapping. The methodology enabled researchers to detect complex forms of genomic variation, critically important for their association with human disease, but previously difficult to detect. The study was published today in Nature Methods, and is a collaboration with scientists at European Molecular Biology Lab, Weill Cornell Medical College, Cold Spring ...

Wind effect following team car can help time trial rider win Tour prologue

Wind effect following team car can help time trial rider win Tour prologue
2015-06-29
Will next Saturday's Tour de France prologue in Utrecht get the winner it deserves? New aerodynamic research at Eindhoven University of Technology (TU/e) shows that riders in a time trial can save vital seconds by riding closer to the following team car. Over a short distance like the prologue of the Tour de France, that can save as much as 6 seconds: enough to make the difference between winning and losing. On longer time trials and events like world championships, the effect can even add up to tens of seconds. Which is why aerodynamics professor Bert Blocken is advising ...

Up, up and away, in the name of science education

2015-06-29
US researchers extol the virtues of high-altitude balloons for science education in a research paper published in the International Journal of Learning Technology. According to Jeremy Straub of the University of North Dakota in Grand Forks, "High-altitude balloons can carry student and scientific payloads to the boundaries of space." This, he suggests, gives students the opportunity to carry out experiments in a cold, near-vacuum, higher-radiation environment at such very high altitudes. "In the process, students experience the awe of space exploration as, through their ...

Experts present new knowledge on bone tissue and its role in bone strength or weakness

2015-06-29
Nyon, Switzerland - June 29, 2015 While there is good understanding of how bone mass, and more recently bone architecture, affects fracture risk, far less is known about the material properties of bone, or how these can impart resilience or fragility to the skeleton. This is changing thanks to the development of new state-of-the-art imaging and other technologies which now allow researchers to gain new insights into the different material properties of bone and their role in bone fragility. Bringing together eight invited contributions by the field's leading experts, ...

Scoring system can help trauma centers improve care during surges in trauma cases

2015-06-29
CHICAGO (June 29, 2015): A scoring system that can identify periods of high activity and increased trauma patient deaths in hospital emergency rooms may help hospitals better prepare for surges in trauma patient volume that come with catastrophic events like the Boston Marathon bombing (April 2013) or disasters like the Amtrak train crash (May 2015) in Philadelphia. Trauma surgeon Peter C. Jenkins, MD, MSc, and a team of investigators from Indiana University and multiple centers developed the scoring system, called the Trauma Surge Index (TSI). They reported their observations ...

The chemistry of grilling (video)

The chemistry of grilling (video)
2015-06-29
WASHINGTON, June 29, 2015 -- If you're firing up the barbecue this week for an Independence Day cookout, you don't want to miss this week's Reactions video. We've got chemistry knowledge that will impress your guests like, "Why is red meat red?" You'll also learn about the amazing Maillard reaction that turns that red meat into a delicious grilled brown. We also settle, once and for all, the age-old debate of gas vs. charcoal. It's all in our latest video: https://youtu.be/RqUEh-B-U-k. Subscribe to the series at http://bit.ly/ACSReactions, and follow us on Twitter @ACSreactions ...

Rare gene variant associated with middle ear infections

2015-06-29
HOUSTON, June 29 -- Many parents have heard the night-time cry of "my ear hurts." For some children, this might happen frequently beginning in infancy and even persist into adulthood. An international consortium led by those at Baylor College of Medicine may have taken the first step on the road to understanding why only some people get frequent painful or chronic middle ear infections. The culprit may be rare genetic variants in a gene called A2ML1. A report on their work appears online in the journal Nature Genetics. In studies led by Dr. Regie Lyn P. Santos-Cortez, ...

His and her pain circuitry in the spinal cord

2015-06-29
New research released today in Nature Neuroscience reveals for the first time that pain is processed in male and female mice using different cells. These findings have far-reaching implications for our basic understanding of pain, how we develop the next generation of medications for chronic pain--which is by far the most prevalent human health condition--and the way we execute basic biomedical research using mice. "Research has demonstrated that men and women have different sensitivity to pain and that more women suffer from chronic pain than men, but the assumption ...

Neighborhood environments and risk for type 2 diabetes

2015-06-29
Neighborhood resources to support greater physical activity and, to a lesser extent, healthy diets appear to be associated with a lower incidence of type 2 diabetes, although the results vary by the method of measurement used, according to an article published online by JAMA Internal Medicine. Type 2 diabetes mellitus (T2DM) is an important cause of death and disability worldwide. Prevention of T2DM has focused largely on behavioral modification. However, the extent to which behavioral modifications will succeed in unsupportive environments remains unknown. Researcher ...
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