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MCAT predicts differently for students who test with extra time

2015-06-09
Among applicants to U.S. medical schools, those with disabilities who obtained extra test administration time for the Medical College Admission Test in use from 1991 to January 2015 had no significant difference in rate of medical school admission but had lower rates of passing the United States Medical Licensing Examination Step examinations and of medical school graduation, according to a study in the June 9 issue of JAMA, a theme issue on the Americans with Disabilities Act. Individuals with documented mental and physical disabilities may receive testing accommodations ...

Examination of gastroenteritis hospitalization rates following use of rotavirus vaccine

2015-06-09
Following implementation of rotavirus vaccination in 2006, all-cause acute gastroenteritis hospitalization rates among U.S. children younger than 5 years of age declined by 31 percent - 55 percent in each of the post-vaccine years from 2008 through 2012, according to a study in the June 9 issue of JAMA. Eyal Leshem, M.D., of the U.S. Centers for Disease Control and Prevention, Atlanta, and colleagues examined both all-cause gastroenteritis and rotavirus-related hospitalizations among children younger than 5 years from 2000 through 2012. The researchers analyzed State ...

INFORMS journal: Microsoft algorithm improves directions in large networks for Bing Maps

2015-06-09
Did the cross-country drive that you planned using an online mapping service take twice as long as expected? In a new study published in the Articles in Advance section of Transportation Science, a journal of the Institute for Operations Research and the Management Sciences (INFORMS), Microsoft researchers working on a project for Bing Maps explain how they developed the first routing engine that satisfies a large number of algorithmic requirements that overcome barriers to generating directions on multi-stage trips like coast-to-coast drives. Customizable Route Planning ...

Are the data underlying the US dietary guidelines flawed?

2015-06-09
Rochester, MN, June 9, 2015 - U.S. government-issued dietary recommendations continue to evolve over time. In a special article published in Mayo Clinic Proceedings, an obesity theorist and cardiovascular health researchers claim that the main source of dietary information used by the U.S. Government's 2015 Dietary Guidelines Advisory Committee (DGAC) is scientifically flawed because the underlying data are primarily informed by memory-based dietary assessment methods (M-BMs) (eg, interviews and surveys). In an editorial response nutrition experts suggest that the purported ...

Keep calm and carry on -- for the sake of your long-term health

2015-06-09
Reacting positively to stressful situations may play a key role in long-term health, according to researchers. In a study measuring adults' reactions to stress and how it affects their bodies, researchers found that adults who fail to maintain positive moods such as cheerfulness or calm when faced with the minor stressors of everyday life appear to have elevated levels of inflammation. Furthermore, women can be at heightened risk. Inflammatory responses are part of the body's ability to protect itself via the immune system. However, chronic -- long-term -- inflammation ...

Insomnia leads to decreased empathy in health care workers

2015-06-09
DARIEN, IL - A new study suggests that insomnia decreases empathy in health care workers and may lead to adverse clinical outcomes and medical errors. Results show that subjects with an Insomnia Severity Index ISI of greater than 8, scored significantly higher across all four subscales of empathy. "Insomnia affects empathy in health care workers which can lead to adverse clinical outcomes," said lead author Venkatesh Basappa Krishnamurthy, MD, assistant professor, Sleep Research and Treatment Center, department of psychiatry, Penn State College of Medicine in Hershey, ...

Mean light timing may influence body mass index and body fat

2015-06-09
DARIEN, IL - A new study suggests that the timing of exposure to moderate levels of light may influence body mass index (BMI) and body fat. Results show that people with more exposure to moderate or higher intensity light earlier in the day had lower body mass index and percent body fat than those with more of their moderate or higher intensity light exposure later in the day. "These results emphasize the importance of getting the majority of your exposure to moderate or higher intensity light during the morning and provide further support that changes to environmental ...

Study: Juvenile incarceration yields less schooling, more crime

2015-06-09
Teenagers who are incarcerated tend to have substantially worse outcomes later in life than those who avoid serving time for similar offenses, according to a distinctive new study co-authored by an MIT scholar. "We find that kids who go into juvenile detention are much less likely to graduate from high school and much more likely to end up in prison as adults," says Joseph Doyle, an economist at the MIT Sloan School of Management and co-author of a new paper detailing the results of the study. Indeed, the research project, which studied the long-term outcomes of ...

Can not having enough to eat lead to poor diabetes management?

2015-06-09
BOSTON (June 9, 2015) - Latinos who worry about having enough food to eat -- so-called food insecurity -- report having a poorer diet and exhibit worse glycemic control than those who aren't worried about having sufficient food to survive, according to a study presented at the American Diabetes Association's 75th Scientific Sessions. The findings suggest that food insecurity should be a factor considered in overall diabetes management. Approximately 24 percent of Latino households in the U.S. were food insecure in 2013, compared to 14 percent for Americans overall, according ...

Are offspring of obese moms pre-programmed for obesity and metabolic disease?

2015-06-09
BOSTON (June 9, 2015) - The evidence is clear that the children of obese parents are prone to obesity themselves, placing them at higher risk for type 2 diabetes, but how and why this occurs remains under investigation. A study being presented at the American Diabetes Association's 75th Scientific Sessions found evidence suggesting that the in utero environment in obese mothers may program a child's cells to accumulate extra fat or develop differences in metabolism that could lead to insulin resistance. "One of the questions that needs to be explored is how children ...

GLP-1 alters how the brain responds to food

2015-06-09
BOSTON (June 9, 2015) - Gut hormone-based medications used to treat diabetes, such as GLP-1 receptor agonists, have also been shown to reduce body weight. Researchers have been working to understand how. This study, presented today at the American Diabetes Association's 75th Scientific Sessions, sheds light on how GLP-1 receptor agonists alter the brain's response to food, possibly reducing cravings and increasing satisfaction while eating. Previous studies have shown that the brains of obese people have a greater response to pictures of food than those of lean people, ...

Filming the film: Scientists observe photographic exposure live at the nanoscale

2015-06-09
Photoinduced chemical reactions are responsible for many fundamental processes and technologies, from energy conversion in nature to micro fabrication by photo-lithography. One process that is known from everyday's life and can be observed by the naked eye, is the exposure of photographic film. At DESY's X-ray light source PETRA III, scientists have now monitored the chemical processes during a photographic exposure at the level of individual nanoscale grains in real-time. The advanced experimental method enables the investigation of a broad variety of chemical and physical ...

'Alzheimer's protein' plays role in maintaining eye health and muscle strength

2015-06-09
Amyloid precursor protein (APP), a key protein implicated in the development Alzheimer's disease, may play an important role in eye and muscle health. In a new report published in the June 2015 issue of The FASEB Journal, scientists have discovered that when proteins that bind to the APP, called FE65 and FE65L1, are deleted, they cause cataracts and muscle weakness in mice. Additionally, this study demonstrates that the expression of laminin, a protein pivotal for the interaction between lens epithelial cells and the lens capsule, is severely altered in mice lenses missing ...

No waiting game: Immediate birth control implant more cost-effective

2015-06-09
Women who have just given birth are often motivated to prevent a rapid, repeat pregnancy. For those who prefer a contraceptive implant, getting the procedure in the hospital immediately after giving birth is more cost-effective than delaying insertion to a 6-8 week postpartum visit, according to a new study by Yale School of Medicine researchers. Published online ahead of print in the July issue of Obstetrics & Gynecology, the study compares costs associated with immediate implant insertion with costs of unintended pregnancy. The implant is placed in the arm and can ...

Birth weight affected by warm temperatures during pregnancy

2015-06-09
BOSTON... June 9, 2015 - Ben-Gurion University of the Negev (BGU) and Harvard University researchers have developed a technique that measures the correlation between air temperature and birth weight. They evaluated the relationship between birth outcomes (focusing on birth weight) and ambient air temperature during pregnancy in Massachusetts between 2000 and 2008. "We found that exposure to high air temperature during pregnancy increases the risk of lower birth weight and can cause preterm birth," according to Dr. Itai Kloog, a senior lecturer in BGU's Department of Geography ...

New species of leafminer on grapevine in Western Cape came from wild grapes

New species of leafminer on grapevine in Western Cape came from wild grapes
2015-06-09
Since 2011 an unknown leafmining moth was observed in table grape orchards and often in large numbers in the Paarl region of the Western Cape (South Africa). Although the effect of the leafmines on the grape vine itself appears to be limited, collateral damage may be more serious, especially when larvae descend from the vine canopy to form a dense curtain of suspended larvae. A new study published in ZooKeys looks into the morphology and biology of the potential pest. Although the leafminer had been seen before in South Africa, it proved impossible to find its name. Entomologist ...

Nearby 'dwarf' galaxy is home to luminous star cluster

2015-06-09
A team of Tel Aviv University and UCLA astronomers have discovered a remarkable cluster of more than a million young stars are forming in a hot, dusty cloud of molecular gases in a tiny galaxy very near our own. The star cluster is buried within a massive gas cloud dubbed "Cloud D" in the NGC 5253 dwarf galaxy, and, although it's a billion times brighter than our sun, is barely visible, hidden by its own hot gases and dust. The star cluster contains more than 7,000 massive "O" stars: the most brilliant stars extant, each a million times more luminous than our sun. "Cloud ...

Molescope to be unveiled at World Dermatology Conference in Vancouver

2015-06-09
Simon Fraser University PhD graduate Maryam Sadeghi will unveil MoleScope™, an innovative hand-held tool that uses a smartphone to monitor skin for signs of cancer, at the World Congress of Dermatology conference in Vancouver June 9-13. Sadeghi has spent three years transitioning from academic research to her start-up venture, MetaOptima Technology Inc. MoleScope™, the company's inaugural product, which enables people to monitor their moles and skin health, share images with family and healthcare providers and eventually, connect skin specialists with people ...

MIPT physicists develop ultrasensitive nanomechanical biosensor

MIPT physicists develop ultrasensitive nanomechanical biosensor
2015-06-09
Two young researchers working at the MIPT Laboratory of Nanooptics and Plasmonics, Dmitry Fedyanin and Yury Stebunov, have developed an ultracompact highly sensitive nanomechanical sensor for analyzing the chemical composition of substances and detecting biological objects, such as viral disease markers, which appear when the immune system responds to incurable or hard-to-cure diseases, including HIV, hepatitis, herpes, and many others. The sensor will enable doctors to identify tumor markers, whose presence in the body signals the emergence and growth of cancerous tumors. The ...

A step towards a type 1 diabetes vaccine by using nanotherapy

2015-06-09
Two years ago, the Immunology of Diabetes Research Group at the Germans Trias Research Institute (at Universitat Autònoma de Barcelona - Campus of International Excellence Sphere) reported a new experimental immunotherapy that prevented the onset of Type 1 Diabetes in mice predisposed to the disease. This work led to more studies with the support of the Spanish Government, Catalan Government and private patrons with a keen interest in it. Thanks to this, the article published today in PLOS ONE describes a new step towards the creation of a vaccine, which in the medium-term ...

Current BMI tests underestimate obesity in teens with disabilities

2015-06-09
June 9, 2015 - New approaches, based on body mass index (BMI) or other simple measures, are needed to improve assessment of obesity in adolescents with physical disabilities, reports a paper in the American Journal of Physical Medicine & Rehabilitation, the official journal of the Association of Academic Physiatrists. The journal is published by Wolters Kluwer. Obesity is a major problem in children and adolescents with mobility limitations, but standard assessments tend to underestimate it, according to the new research by Brooks C. Wingo, PhD, of University of Alabama ...

Small molecules change biological clock rhythm

Small molecules change biological clock rhythm
2015-06-09
Nagoya, Japan - A team of chemists and biologists at the Institute of Transformative Bio-Molecules (ITbM), Nagoya University have succeeded in finding new molecules that change the circadian rhythm in mammals by applying synthetic chemistry methods, which makes use of highly selective metal catalysts. Most living organisms have a biological clock with an approximately 24-hour circadian rhythm, which regulates important body functions such as sleep/wake cycles, hormone secretion, and metabolism. Disruption of the circadian rhythm by genetic mutations and environmental ...

Been there? Done that? If you are sure, thank your 'memory cells'

2015-06-09
LOS ANGELES (JUNE 8, 2015) - The witness on the stand says he saw the accused at the scene of the crime. Is he sure? How sure? The jury's verdict could hinge on that level of certainty. Many decisions we make every day are influenced by our memories and the confidence we have in them. But very little is known about how we decide whether we can trust a memory or not. A new Cedars-Sinai study provides some of the answers. Researchers have identified a unique set of neurons in the medial temporal lobe, an area of the brain where memories and memory-based decisions are ...

Largest-ever scientific camera trapping survey reveals 'secret lives of the Serengeti'

2015-06-09
The use of camera traps -- remote automatic cameras triggered by heat or motion -- has revolutionized wildlife ecology and conservation research. But the large number of images generated through the traps creates the problem of categorizing and analyzing all the images. For a recent project conducted in the Serengeti National Park, Alexandra Swanson, turned to another relatively new technology -- a citizen science platform. The Snapshot Serengeti project asked non-scientist volunteers to review 1.2 million sets of images. A description of the project, 'Snapshot Serengeti, ...

Clinicians reluctant to prescribe medication that counteracts effects of opioid overdose

2015-06-09
A variety of factors including questions about risk and reluctance to offend patients limits clinician willingness to prescribe a potentially life-saving medication that counteracts the effects of an opioid overdose, according to a Kaiser Permanente Colorado study published today in the Journal of General Internal Medicine. The number of fatal overdoses from opioid medications has quadrupled in the U.S. since 1999. According to the Centers for Disease Control and Prevention (CDC), each day 44 people die of prescription painkiller overdoses. In the event of an overdose, ...
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