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Cargo delivery by polymers

2021-01-22
Degradable, bio-based polymers offer options for chemical recycling, and they can be a tool to store and release useful molecules. Scientists have developed a class of sugar-based polymers that are degradable through acid hydrolysis. The researchers also integrated "cargo" molecules in the polymer, which are designed to split off after polymer degradation. Degradable, cargo-bearing polymers are important for medical and sensor applications, says the study published in the journal Angewandte Chemie. Most plastics resist natural degradation processes. Consequently, increasing contamination of the environment with plastics has led to a call for degradable plastics. Such materials can be subjected to chemical recycling processes, in which chemical reactions break up polymer bonds. ...

Microbiome Search Engine 2 helps researchers explore microbiome space

Microbiome Search Engine 2 helps researchers explore microbiome space
2021-01-22
Metagenomics - the study of genetic material from an environmental sample - is growing as species evolve or are discovered across the globe. To correlate the newly developed microbiomes with existing data sets, a team of researchers based in China has developed the Microbiome Search Engine 2 (MSE 2). It was published on Jan. 19 in mSystems, a journal of the American Society for Microbiology. "Here, we introduce MSE 2, a microbiome database platform for searching query microbiomes in the global metagenome data space based on taxonomic or functional similarity of the whole microbiome," ...

Research shows preference for male children is declining in Bangladesh

2021-01-22
Research from the University of Kent has demonstrated a decline in 'son preference' by women of childbearing age in Bangladesh. However, the study also shows that fertility decisions are still influenced according to son preference. The paper, 'Is son preference disappearing from Bangladesh?', surveyed a nationally representative sample of Bangladeshi women of childbearing age, born between 1975 and 1994, to assess how son preference is evolving. The term 'son preference' refers to any situation where parents value sons over daughters and make resulting choices accordingly, which can have a strong economic and demographic impact. The study finds that among women of childbearing age in ...

CT identifies patients with high-risk nonalcoholic fatty liver disease (NAFLD)

CT identifies patients with high-risk nonalcoholic fatty liver disease (NAFLD)
2021-01-22
Leesburg, VA, January 22, 2021--According to ARRS' American Journal of Roentgenology (AJR), Fibrosis-4 (FIB-4) and multiple CT findings can identify patients with high-risk nonalcoholic fatty liver disease (NAFLD)--advanced fibrosis or cirrhosis, that is--though the presence of nonalcoholic steatohepatitis (NASH) remains elusive on CT. "Subjective assessment of multiple morphologic and separately quantified parameters by trained readers and a simple quantitative three-parameter model combining two CT features, liver surface nodularity (LSN) and liver segmental volume ratio (LSVR), and a clinical score (FIB-4) showed good association with presence of advanced fibrosis," wrote first author Meghan G. Lubner from the department of radiology at the University of Wisconsin School ...

Magnetic waves explain mystery of Sun's outer layer

2021-01-22
The Sun's extremely hot outer layer, the corona, has a very different chemical composition from the cooler inner layers, but the reason for this has puzzled scientists for decades. One explanation is that, in the middle layer (the chromosphere), magnetic waves exert a force that separates the Sun's plasma into different components, so that only the ion particles are transported into the corona, while leaving neutral particles behind (thus leading to a build-up of elements such as iron, silicon and magnesium in the outer atmosphere). Now, in a new study published ...

Patients of Asian and black backgrounds more likely to die from COVID, large study reveals

2021-01-22
Patients of Asian and black backgrounds suffered disproportionate rates of premature death from COVID-19, according to a study of 1,737 patients by Queen Mary University of London and Barts Health NHS Trust. The study, published in BMJ Open, is one of the most comprehensive studies exploring COVID-19 outcomes in black, Asian and minority ethnic populations so far reported, from one of the largest and most diverse UK hospital COVID-19 cohorts, representing a majority ethnically diverse population (only 35.2 per cent of patients identified as White ethnicity). The work resulted from a new interdisciplinary collaboration between intensive care physicians and HIV physicians. The researchers looked at data from all patients ...

Geoscientists reconstruct 6.5 million years of sea level stands

Geoscientists reconstruct 6.5 million years of sea level stands
2021-01-22
TAMPA, Fla. (January 22, 2021)- The pressing concern posed by rising sea levels has created a critical need for scientists to precisely predict how quickly the oceans will rise in coming centuries. To gain insight into future ice sheet stability and sea-level rise, new research from an international team led by University of South Florida geoscientists is drawing on evidence from past interglacial periods when Earth's climate was warmer than today. Using deposits in the caves of the Mediterranean island of Mallorca, known as phreatic overgrowths ...

Stanford: forecasting coastal water quality

Stanford: forecasting coastal water quality
2021-01-22
Less than two days of water quality sampling at local beaches may be all that's needed to reduce illnesses among millions of beachgoers every year due to contaminated water, according to new Stanford research. The study, published in Environmental Science & Technology, presents a modeling framework that dependably predicts water quality at beaches after only a day or two of frequent water sampling. The approach, tested in California, could be used to keep tabs on otherwise unmonitored coastal areas, which is key to protecting the well-being of beachgoers and thriving ocean economies ...

Methods in studying cycad leaf nutrition found to be inconsistent and incomplete

Methods in studying cycad leaf nutrition found to be inconsistent and incomplete
2021-01-22
Collective research to date regarding nutrients found in the leaves of contemporary cycad species has been inconsistent as far as data collection and narrow in scope, according to a University of Guam-led literature review published on Nov. 19 in Horticulturae journal. Understanding nutrient accumulation within cycads is essential to effective horticultural management, and more importantly, conservation of this plant group, which is highly prized within the horticulture trade and also threatened worldwide. "Cycads comprise the most threatened group of plants worldwide, ...

PTSD link to pandemic panic

2021-01-22
Even at the start of the COVID-19 pandemic last year, people around the world became more fearful of what could happen to them or their family. A new Flinders University study of 1040 online participants from five western countries published in PLOS ONE explores people's response to the stresses of the escalating pandemic, finding more than 13% of the sample had post-traumatic stress disorder (PTSD) related symptoms consistent with levels necessary to qualify for a clinical diagnosis. With ongoing economic and social fallout, and death toll of more than 2 million, the team of psychology researchers warn more needs to be done to cope with ...

Placental function can illuminate future disease in adults and children

2021-01-22
AURORA, Colo. (Jan. 22, 2021) - Researchers at the University of Colorado Anschutz Medical Campus have discovered a direct association between placental function in pregnant women and future metabolic disorders in children and adults, a finding that could lead to earlier intervention and diagnosis of disease. "We've known for some time that many major diseases in adults like diabetes and cardiovascular disease are at least partly caused by problems during fetal life," said the study's senior author Thomas Jansson, MD, PhD, professor of Obstetrics & Gynecology ...

MRI helps unravel the mysteries of sleep

2021-01-22
Our state of consciousness changes significantly during stages of deep sleep, just as it does in a coma or under general anesthesia. Scientists have long believed - but couldn't be certain - that brain activity declines when we sleep. Most research on sleep is conducted using electroencephalography (EEG), a method that entails measuring brain activity through electrodes placed along a patient's scalp. However, Anjali Tarun, a doctoral assistant at EPFL's Medical Image Processing Laboratory within the School of Engineering, decided to investigate brain activity during sleep using magnetic resonance ...

Rhesus macaques develop promising immune response to SARS-CoV-2

2021-01-22
In a promising result for the success of vaccines against COVID-19, rhesus macaque monkeys infected with the human coronavirus SARS-CoV-2 developed protective immune responses that might be reproduced with a vaccine. The work was carried out at the California National Primate Research Center at the University of California, Davis and is published Jan. 22 in the journal Nature Communications. "These results suggest that vaccines inducing durable protective immunity against SARS-CoV-2 do so by stimulating robust germinal center responses - a question that can be effectively answered ...

Record-breaking laser link could help us test whether Einstein was right

Record-breaking laser link could help us test whether Einstein was right
2021-01-22
Scientists from the International Centre for Radio Astronomy Research (ICRAR) and The University of Western Australia (UWA) have set a world record for the most stable transmission of a laser signal through the atmosphere. In a study published today in the journal Nature Communications, Australian researchers teamed up with researchers from the French National Centre for Space Studies (CNES) and the French metrology lab Systèmes de Référence Temps-Espace (SYRTE) at Paris Observatory. The team set the world record for the most stable laser transmission by combining the Aussies' 'phase stabilisation' technology with advanced self-guiding optical ...

Growing up in a bilingual home has lasting benefits

2021-01-22
New research has found that growing up in a bilingual home can provide unexpected cognitive benefits later in life. The study, published in the journal Scientific Reports, demonstrates for the first time that adults who acquired their second language as a young child (early bilinguals) are quicker at shifting attention and quicker at detecting visual changes compared to adults who learnt their second language later in life (late bilinguals). Led by Dr Dean D'Souza of Anglia Ruskin University (ARU), the research saw 127 adults take part in two separate ...

Study highlights factors that predict success for treating canine behavioral disorders

Study highlights factors that predict success for treating canine behavioral disorders
2021-01-22
There is a saying that you can't teach old dogs new tricks. When it comes to canine behavioral problems, age is only one factor that can predict how well a pet may respond to clinical intervention. In a paper published in Frontiers in Veterinary Science, researchers provide the first evidence on the importance of not just a dog's age, sex and size on treatment success, but the owner's personality and the kind of bond that human and animal share. The study analyzed the physiological and psychological characteristics of 131 dog-owner pairs who attended a veterinary behavioral service over a six-month period. The statistical results were based on a behavioral assessment questionnaire that was given at the beginning, middle and end of the ...

Role of dams in reducing global flood exposure under climate change

2021-01-22
A new collaborative study led by researchers at the National Institute for Environmental Studies, the University of Tokyo, and Michigan State University exposes the role of dams for mitigating flood risk under climate change. Flood is amongst the costliest natural disasters. Globally, flood risk is projected to increase in the future, driven by climate change and population growth. The role of dams in flood mitigation, previously unaccounted for, was found to decrease by approximately 15% the number of people globally exposed to historical once-in-100-year ...

Sliding life expectancy poses gender and inequity questions

2021-01-22
Questions about why such affluent western societies are facing a reversal in life expectancy are sounding loud alarm bells for Professor Fran Baum, Matthew Flinders Distinguished Professor and Director of the Southgate Institute for Health, Society and Equity. Professor Baum is lead author of a study that offers a new perspective on why women live longer than men - noting with concern that while women live longer, many of the recognised social determinants of health are worse for women than men. The study serves an important reminder of why policy makers need to receive more carefully nuanced research that drills into specific gender data that can best inform public health policy initiatives. "We need gendered analysis to shape ...

Navigating uncertainty: Why we need decision theory during a pandemic

Navigating uncertainty: Why we need decision theory during a pandemic
2021-01-22
During a pandemic, decisions have to be made under time pressure and amid scientific uncertainty, with potential disagreements among experts and models. With COVID-19, especially during the first wave, there was uncertainty about the virus transmissibility, the disease severity, the future evolution of the pandemic and the effectiveness of the proposed policy interventions, such as wearing face masks or closing schools. Together with a group of epidemiologists and economists, including the Nobel Prize winner Lars Peter Hansen, Bocconi professors Massimo Marinacci, AXA-Bocconi Chair in Risk, and Valentina Bosetti investigated how modern decision theory can help policymakers ...

Covid lockdown loneliness linked to more depressive symptoms in older adults

2021-01-22
Loneliness in adults aged 50 and over during the COVID-19 lockdown was linked to worsening depressive and other mental health symptoms, according to a large-scale online study. Loneliness emerged as a key factor linked to worsening symptoms of depression and anxiety in a study of more than 3,000 people aged 50 or over led by the University of Exeter and King's College London, and funded by The National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre (BRC) . Researchers had access to data going back to 2015 for participants of the ...

Do promotions make consumers more generous?

2021-01-22
Researchers from Nanyang Technological University (Singapore), Shanghai Jiao Tong University, and University of Hong Kong published a new paper in the Journal of Marketing that examines why and how charitable organizations can increase donations by soliciting consumers after retailers' price promotions. The study, forthcoming in the Journal of Marketing, is titled "Do Promotions Make Consumers More Generous? The Impact of Price Promotions on Consumers' Donation Behavior" and is authored by Kuangjie Zhang, Fengyan Cai, and Zhengyu Shi. Giving Tuesday, a global generosity movement, takes place each year on the Tuesday after US Thanksgiving (immediately after Black Friday and Cyber Monday sales). Charitable donations generally see a big boost on Giving Tuesday. This year, American consumers ...

Combined river flows could send up to 3 billion microplastics a day into the Bay of Bengal

Combined river flows could send up to 3 billion microplastics a day into the Bay of Bengal
2021-01-22
The Ganges River - with the combined flows of the Brahmaputra and Meghna rivers - could be responsible for up to 3 billion microplastic particles entering the Bay of Bengal every day, according to new research. The study represents the first investigation of microplastic abundance, characteristics and seasonal variation along the river and was conducted using samples collected by an international team of scientists as part of the National Geographic Society's END ...

New combination of immunotherapies shows great promise for treating lung cancer

New combination of immunotherapies shows great promise for treating lung cancer
2021-01-22
HAMILTON, ON, Jan. 21, 2020 -- McMaster University researchers have established in lab settings that a novel combination of two forms of immunotherapy can be highly effective for treating lung cancer, which causes more deaths than any other form of cancer. The new treatment, yet to be tested on patients, uses one form of therapy to kill a significant number of lung tumor cells, while triggering changes to the tumor that enable the second therapy to finish the job. The first therapy employs suppressed "natural killer" immune cells by extracting them from patients' tumours ...

Study suggests coffee temporarily counteracts effect of sleep loss on cognitive function

2021-01-22
A new study exploring the impact of repeated sleep loss during a simulated working week has found that consuming caffeinated coffee during the day helps to minimize reductions in attention and cognitive function, compared to decaffeinated coffee1. While this effect occurred in the first three-to-four days of restricted sleep, by the fifth and final day, no difference was seen between caffeinated and decaffeinated coffee drinkers. This therefore suggests that the beneficial effects of coffee for people with restricted sleep are temporary1. It is estimated that over 30% of adult Western populations sleep less than the recommended seven to eight hours on weekday nights and 15% regularly sleep less than six hours2,3. This can ...

The Lancet and The Lancet Oncology: Global demand for cancer surgery set to grow by almost 5 million procedures within 20 years, with greatest burden in low-income countries

2021-01-22
A modelling study suggests that demand for cancer surgery will rise by 52% - equal to 4.7 million procedures - between 2018 and 2040, with the greatest relative increase in low-income countries, which already have substantially lower staffing levels than high-income countries. A separate observational study comparing global cancer surgery outcomes also suggests that patients in low- and middle-income countries (LMICs) are four times more likely to die from colorectal or gastric cancer (odds of 4.59 and 3.72, respectively) than those in high-income countries (HICs) currently, and that poor provision of care ...
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