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Physical trauma associated with onset of psoriatic arthritis among psoriasis patients

2015-06-11
Rome, Italy, 11 June 2015: The results of a large population study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) showed an increased risk of developing Psoriatic Arthritis (PsA) among psoriasis patients exposed to physical trauma, particularly when the trauma involved bone and/or joints. "This is the first sizable population-based cohort study to determine the risk of PsA following trauma in psoriasis patients," said Dr Thorvardur Love, senior author from Landspitali University Hospital, Iceland. "Our findings highlight the importance ...

Non-steroidal anti-inflammatory drugs inhibit ovulation after just 10 days

2015-06-11
Rome, June 11 -- The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) show that diclofenac, naproxen and etoricoxib significantly inhibit ovulation in women with mild musculoskeletal pain. Of the women receiving NSAIDs, only 6.3 percent (diclofenac), 25 percent (naproxen) and 27.3 percent (etoricoxib) ovulated, compared with 100 percent of the control group. These findings suggest that readily available non-steroidal anti-inflammatory drugs (NSAIDs) could have a harmful effect on fertility, and should be used ...

Low birth weight and childhood infections predict ankylosing spondylitis

2015-06-11
Rome, Italy, 11 June 2015: The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference showed that a diagnosis of ankylosing spondylitis (AS) can be predicted by low birth weight, having older siblings and hospitalisation for infection between the ages of 5-16 years. These data suggest that these factors play an important role in the pathogenesis of the disease. AS is a painful and progressive form of arthritis caused by chronic inflammation of the joints in the spine. Prevalence of AS varies globally, ...

New iPad app helps children and young people with JIA communicate their pain experiences

2015-06-11
Rome, Italy, 11 June 2015: The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) demonstrated the value of a new interactive iPad app that helps young people with Juvenile Idiopathic Arthritis (JIA) describe their pain. Almost all of the children preferred the new digital tool, aptly titled 'This Feeling', to other conventional methods and felt it was an interesting and engaging way to communicate about their experiences of pain.1 "It is vital for children and young people to be able to communicate about their pain ...

Unique bacterial fingerprint identified in systemic sclerosis

2015-06-11
Rome, Italy, 11 June 2015: The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference showed that people with systemic sclerosis (SSc) have a unique bacterial signature in their colon, when compared with healthy people. These findings suggest that changes in the gut ecology could contribute to the clinical symptoms of SSc, and could be used to diagnose the condition, and in the development of alternative treatments. Systemic sclerosis (SSc) is an autoimmune disease affecting multiple organs. Up to 90% ...

Women with lupus and APS at risk of reduced fertility and pregnancy complication

2015-06-11
Rome, June 11 -- New recommendations by EULAR for women's health and pregnancy in patients with systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS) were presented today at the European League Against Rheumatism Annual Congress (EULAR 2015). Developed by expert consensus, these evidence-based recommendations provide crucial guidance to support family planning, assisted reproduction, pregnancy and the menopause in these patients. 'APS and SLE disproportionately affect women, typically starting when they are at their most fertile, and leaving women ...

Movement in ADHD may help children think, perform better in school

2015-06-11
The constant movement of children with attention-deficit/hyperactivity disorder (ADHD) may be distracting -- but the fidgeting also may improve their cognitive performance, a study by researchers with the UC Davis MIND Institute has found. The study of pre-teens and teenagers with ADHD examined how movement -- its intensity and frequency -- correlated with accuracy on cognitively demanding tasks requiring good attention. It found that participants who moved more intensely exhibited substantially better cognitive performance. The study, "A trial-by-trial analysis reveals ...

Wild mongooses avoid inbreeding with unusual reproductive strategy

Wild mongooses avoid inbreeding with unusual reproductive strategy
2015-06-11
Researchers studying banded mongooses in Uganda have discovered that these small mammals are able to discriminate between relatives and non-relatives to avoid inbreeding even when mating within their own closely related social group. Inbreeding can be a big problem for social species such as banded mongooses because they grow up in social groups consisting mainly of close relatives. This study is the first to suggest that social animals are able to avoid the costs of inbreeding without relying on un-related mating partners from other social groups. Dr Jennifer Sanderson, ...

Comorbid conditions associated with worse lung cancer survival

2015-06-11
Main Findings: Lung cancer patients with comorbid conditions such as chronic obstructive pulmonary disease, diabetes, or congestive heart failure had a higher risk of death than lung cancer patients without comorbid conditions. Journal in Which the Study was Published: Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research Author: K.M. Monirul Islam, MD, PhD, an assistant professor in the Department of Epidemiology at the University of Nebraska Medical Center College of Public Health Background: Lung cancer is the leading ...

Children's exposure to secondhand smoke in England has dropped 80 percent since 1998

2015-06-11
A new study published today by the scientific journal Addiction finds that in England, children's exposure to second-hand smoke has declined by approximately 80% since 1998. Also, an emerging social norm in England has led to the adoption of smoke-free homes not only when parents are non-smokers but also when they smoke. The proportion of children living in a home reported to be smoke-free increased from 63% in 1998 to 87.3% in 2012. The study gathered data from over 35,000 children who participated in the annual Health Survey for England (HSE) from 1998 to 2012. ...

Is eating for 2 a good idea? Maintaining a healthy weight during pregnancy helps mother and baby

2015-06-11
Pregnant women can improve their health and even reduce the risk of complications during childbirth by maintaining a healthy weight through diet and exercise. Research has shown that gaining too much weight during pregnancy increases the risk of gestational diabetes, high blood pressure, large babies, and delivery by caesarean section; and newborns with large birth weights are at risk of childhood obesity. An updated systematic review published in The Cochrane Library reveals that diet or exercise interventions, or a combination of both, can prevent excessive weight gain ...

Weekend screen time linked to poorer bone health in teen boys

2015-06-11
Weekend screen time is linked to poorer teen bone health--but only in boys, reveals research published in the online journal BMJ Open. The apparent lack of impact of leisure screen time on teen girls' bone health may be explained by their different body fat distribution, suggest the researchers. They base their findings on participants in the Tromsø Fit Futures Study in Norway, which involved 961 of the region's 15-17 year old school pupils in 2010-11 (first wave) and 688 (66%) of this original group two years later in 2012-13 (second wave). At both time periods, ...

Aerobic exercise seems to curb asthma severity and improves quality of life

2015-06-11
Aerobic exercise seems to curb the severity of asthma symptoms and improves quality of life, finds a small study published online in the journal Thorax. It should be routinely added to the drug treatment of moderate to severe asthma, suggest the researchers, who point out that people with asthma often avoid exercise for fear of triggering symptoms. Exercise has been recommended in the past for asthma patients, because it improves physical fitness, overall quality of life, and reduces the need for inhalers. But it has not been clear whether the pros outweigh the cons. The ...

Additives in low tar ('light') and e-cigarettes may reinforce nicotine dependence

2015-06-11
Pyrazine additives in low tar ('light') and e-cigarettes may be reinforcing the addictive qualities of nicotine, and should be strictly regulated, concludes research published online in the journal Tobacco Control. The evidence suggests that pyrazines have sensory and pharmacological effects which act independently of, and in tandem with, nicotine, and were developed by the tobacco industry to make low tar ('light') cigarettes taste richer and smoother, and boost sales. Nicotine dependence is a complex process, but is primarily caused by the ability of nicotine to prompt ...

University of Windsor sexual assault study reaches NEJM

2015-06-11
Sexual assault resistance training works, according to a new University of Windsor-led study published today in the New England Journal of Medicine. While only those who commit acts of sexual violence can stop sexual assault, women may be able to reduce the likelihood that they will be the victim of a completed rape. To use a medical analogy, there is not much we can do about pathogens such as bacteria or viruses already in our environment, but we can take steps to boost our immune system so we can better resist these pathogens when we come into contact with them. This ...

Study discovers new method of classifying low-grade brain tumors

2015-06-11
CLEVELAND - A Case Comprehensive Cancer Center (CCCC) brain surgeon and neurosurgery professor is among the primary authors of a new approach to classifying tumors that could lead to significant improvements in their diagnosis and treatment. The research and recommendations appear online June 10 in The New England Journal of Medicine. Andrew Sloan, MD, Director of the Brain Tumor and Neuro-Oncology Center at University Hospitals Case Medical Center, said the new classification system has the potential to provide far more accurate assessments of brain tumors known as low ...

Strategies needed for community health worker programs to solve health care challenges

2015-06-11
PHILADELPHIA -- Community health workers (CHW) are expected to be a growing and vital part of healthcare delivery in the United States as the Affordable Care Act is fully implemented. A slate of steps detailing how CHW programs can maximize their effectiveness and impact on patients and healthcare spending is provided in a new perspective piece in the New England Journal of Medicine by experts at the University of Pennsylvania's Perelman School of Medicine and New York University. The piece offers guidance for the growing number of organizations who are looking to community ...

Which artificial pancreas system is the best for children with type 1 diabetes?

2015-06-11
Montréal, June 10, 2015 - A Montréal research team, co-supervised by Dr. Rémi Rabasa-Lhoret from the IRCM and Dr. Laurent Legault from the Montreal Children's Hospital, undertook the first paediatric outpatient study to compare three alternative treatments for type 1 diabetes. The results, published this week in the scientific journal The Lancet Diabetes & Endocrinology, shows the dual-hormone artificial pancreas provides the most benefits by reducing the time spent in nocturnal hypoglycaemia. The study conducted with children and adolescents with type ...

Specialized proteins may be detected in blood of people with Alzheimer's disease

2015-06-10
MINNEAPOLIS - Specialized brain proteins that are involved in the removal of damaged nerve cell materials may be detected in the blood of people who were diagnosed with mild cognitive impairment or dementia due to Alzheimer's disease. In a select group of people who later developed dementia, the levels of the lysosomal proteins were abnormal while the people still had no problems with memory or thinking skills, according to a study published in the June 10, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology. "These proteins ...

Keeping mind, body active may not protect against underlying signs of Alzheimer's

2015-06-10
MINNEAPOLIS - While participating in physical activities such as bike riding, dancing, walking and gardening and mentally stimulating activities such as crosswords and reading may reduce the risk of Alzheimer's disease, they may not do so by affecting the underlying markers for the disease, according to a study published in the June 10, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology. "While a lifelong history of physical and mental activity may support better memory and thinking performance, this relationship may possibly ...

NAMS supports judicious use of systemic hormone therapy even after age 65

2015-06-10
CLEVELAND, June 8 -- As new research continues to document the incidence of bothersome hot flashes lasting into the mid-60s for many women, the medical industry has had to rethink the way it approaches menopause therapy. As a result, earlier this month The North American Menopause Society (NAMS) issued its statement on the continuing use of systemic hormone therapy after age 65. 'The official position of NAMS is that there shouldn't be hard and fast rules against hormones after age 65,' said Wulf Utian, M.D., medical director for NAMS. 'Yes, there may be safety concerns, ...

More Frequent overnight hot flashes linked with brain scan changes

2015-06-10
PITTSBURGH, June 10 -- Women who experience more hot flashes, particularly while sleeping, during the menopause transition are more likely to have brain changes reflecting a higher risk for cerebrovascular disease, such as stroke and other brain blood flow problems, according to a pilot study led by researchers at the University of Pittsburgh School of Medicine published online today in Menopause and funded by the National Institutes of Health. More than 70 percent of women have hot flashes -- a sudden feeling of intense warmth and sweatiness -- while transitioning into ...

Report: one in four Baltimore residents live in a food desert

2015-06-10
A new report by researchers at the Johns Hopkins Center for a Livable Future (CLF), in collaboration with the Baltimore Food Policy Initiative, found that one in four of the city's residents live in so-called food deserts with limited access to healthy foods. The report, released today, is available online on the Center for a Livable Future's Maryland Food System Map website. The findings were highlighted at a press conference featuring Baltimore City Mayor Stephanie Rawlings-Blake, other city officials and CLF representatives. Neighborhoods with food deserts have ...

New tool better protects beachgoers from harmful bacteria levels

New tool better protects beachgoers from harmful bacteria levels
2015-06-10
MIAMI - An international team, led by researchers at the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science, has developed a new, timelier method to identify harmful bacteria levels on recreational beaches. The new model provides beach managers with a better prediction tool to identify when closures are required to protect beachgoers from harmful contaminates in the water. "The development of this new model has allowed us, for the first time, to estimate contamination levels on beaches subject to nonpoint source pollution, in particular from ...

Short boys are 2 to 3 times as likely as short girls to receive growth hormone

2015-06-10
Short boys are three times more likely than short girls to receive recombinant human growth hormone treatment for idiopathic short stature (ISS), even though in a general pediatric population, equal proportions of both genders fall under the height threshold designating ISS. Researchers who analyzed records of over 283,000 U.S. children and adolescents found a clear-cut and persistent gender bias in the provision of treatment. "Growth is an important sign of child health, so growth failure merits equal consideration for both boys and girls," said study leader Adda Grimberg, ...
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