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Older people getting smarter, but not fitter

2015-08-31
Older populations are scoring better on cognitive tests than people of the same age did in the past --a trend that could be linked to higher education rates and increased use of technology in our daily lives, say IIASA population researchers. People over age 50 are scoring increasingly better on tests of cognitive function, according to a new study published in the journal PLOS ONE. At the same time, however, the study showed that average physical health of the older population has declined. The study relied on representative survey data from Germany which measured cognitive ...

Gene leads to nearsightedness when kids read

Gene leads to nearsightedness when kids read
2015-08-31
NEW YORK, NY (August 31, 2015) -- Vision researchers at Columbia University Medical Center have discovered a gene that causes myopia, but only in people who spend a lot of time in childhood reading or doing other "nearwork." Using a database of approximately 14,000 people, the researchers found that those with a certain variant of the gene - called APLP2 - were five times more likely to develop myopia in their teens if they had read an hour or more each day in their childhood. Those who carried the APLP2 risk variant but spent less time reading had no additional risk ...

Dialect influences Appalachian students' experiences in college

2015-08-31
An in-depth dialect study from NC State University researchers shows that some students from rural Appalachia feel that their dialects put them at a disadvantage in a college classroom, even in the South. The Journal of Higher Education study raises important questions about language as a type of diversity that isn't always celebrated on campus, says lead author Stephany Dunstan, a linguist and associate director of assessment at NC State. In their interviews, some rural Appalachian students recalled times when they spoke up in class only to be met with snickers for ...

We've all got a blind spot, but it can be shrunk

2015-08-31
You've probably never noticed, but the human eye includes an unavoidable blind spot. That's because the optic nerve that sends visual signals to the brain must pass through the retina, which creates a hole in that light-sensitive layer of tissue. When images project to that precise location, we miss them. Now researchers reporting in the Cell Press journal Current Biology on August 31 have some good news: this blind spot can be effectively "shrunk" with training, despite the fact that the hole in our visual field cannot be. The findings raise the possibility that similar ...

Heart rate, heart rate variability in older adults linked to poorer function

2015-08-31
A higher resting heart rate and lower heart rate variability in older adults at high risk of heart disease are associated with poorer ability to function in daily life as well as future decline, according to a new research in CMAJ (Canadian Medical Association Journal). "It has been hypothesized that heart rate and heart rate variability are markers of frailty, an increased vulnerability to stressors and functional decline," writes Dr. Behnam Sabayan, Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands, with coauthors. "However, ...

Lyme disease testing: Canadians may receive false-positives from some US labs

2015-08-31
Lyme disease is becoming increasingly common in Canada, and Canadians with Lyme disease symptoms may seek diagnoses from laboratories in the United States, although many of the results will be false-positives, according to a commentary in CMAJ (Canadian Medical Association Journal). "Patients with chronic subjective symptoms without a diagnosis can be vulnerable and desperate for an answer as to the cause of their illness," writes Dr. Dan Gregson, divisions of Medical Microbiology and Infectious Diseases, departments of Pathology and Laboratory Medicine, and Medicine, ...

Temple Lung Center study shows benefits for COPD patients using digital health application

2015-08-31
(Philadelphia, PA) - Early intervention facilitated by a digital health application for reporting symptoms of Chronic Obstructive Pulmonary Disease (COPD) provides key benefits for patients, according to the results of a Temple-led, two-year clinical study. COPD is a serious chronic respiratory disease that is often characterized by flare-ups, called acute exacerbations, in which the patient may experience increased coughing, mucus, shortness of breath, wheezing, and a feeling of tightness in their chest. If exacerbation symptoms are not detected and treated in a timely ...

Raising pay can reduce smoking rates

2015-08-31
(SACRAMENTO, Calif.) -- In addition to restricting when and where tobacco is used at work, UC Davis Health System research shows that employers can do something else to reduce smoking: raise wages. Published in the August issue of the Annals of Epidemiology, the study found that a 10 percent increase in wages leads to about a 5 percent drop in smoking rates among workers who are male or who have high school educations or less and improves their overall chances of quitting smoking from 17 to 20 percent. "Our findings are especially important as inflation-adjusted wages ...

Magnetic stimulation effective in helping Parkinson's patients walk

2015-08-31
Amsterdam, NL, August 31, 2015 - About 50% of patients with Parkinson's disease (PD) experience freezing of gait (FOG), an inability to move forward while walking. This can affect not only mobility but also balance. In a new study published in Restorative Neurology and Neuroscience, researchers report that repetitive transcranial magnetic stimulation (rTMS) can reduce FOG and improve other motor skills in PD patients. In a study conducted by researchers at the Sungkyunkwan University School of Medicine, Seoul, Korea, 17 PD patients experiencing FOG were treated with either ...

Medication treatment for opioid use disorders in primary care increases patient access

2015-08-31
BOSTON - Clinicians at Boston Medical Center (BMC) showed that expanding the number of sites offering office-based opioid treatment with buprenorphine (OBOT B) utilizing addiction nurse care managers, trainings and technical support resulted in more physicians becoming waivered to prescribe buprenorphine and more patients accessing treatment at sites across Massachusetts. This model, highlighted online in the Journal of Substance Abuse Treatment, demonstrates the efficacy of this medication-assisted treatment modality as a sustainable way to treat greater numbers of patients ...

NASA sees Hurricane Jimena's large eye

NASA sees Hurricane Jimena's large eye
2015-08-31
NASA's Aqua satellite and NOAA's GOES-East satellites provided views of Hurricane Jimena that showed it maintained a large eye and powerful thunderstorms around it. On August 31, Jimena continued moving through the Eastern Pacific as a major hurricane. An infrared image from NOAA's GOES-West satellite on August 31 at 8:00 a.m. EDT revealed that Hurricane Jimena's wide-eye continued to be cloud free. The GOES image also showed thick bands of powerful thunderstorms circling the eye. The Atmospheric Infrared Sounder or AIRS instrument aboard Aqua gathers infrared data ...

'Happy Meals' bill could improve healthfulness of fast food meals for kids in NYC

2015-08-31
A bill to improve the nutritional value of fast food restaurant meals marketed to children--like McDonald's Happy Meals--could have a wide enough impact to reduce calories, fat, and sodium, according to a new study led by researchers at NYU Langone Medical Center. The study, which will publish in the American Journal of Preventive Medicine online on August 31, includes collaboration from NYU College of Global Public Health, NYU Wagner Graduate School of Public Service, and NYU Steinhardt School of Culture, Education, and Human Development. The "Healthy Happy Meals" ...

Scientists 'squeeze' light one particle at a time

Scientists 'squeeze' light one particle at a time
2015-08-31
A team of scientists has successfully measured particles of light being "squeezed", in an experiment that had been written off in physics textbooks as impossible to observe. Squeezing is a strange phenomenon of quantum physics. It creates a very specific form of light which is "low-noise" and is potentially useful in technology designed to pick up faint signals, such as the detection of gravitational waves. The standard approach to squeezing light involves firing an intense laser beam at a material, usually a non-linear crystal, which produces the desired effect. For ...

Deciphering the olfactory receptor code

Deciphering the olfactory receptor code
2015-08-31
In animals, numerous behaviors are governed by the olfactory perception of their surrounding world. Whether originating in the nose of a mammal or the antennas of an insect, perception results from the combined activation of multiple receptors located in these organs. Identifying the full repertoire of receptors stimulated by a given odorant would represent a key step in deciphering the code that mediates these behaviors. To this end, a tool that provides a complete olfactory receptor signature corresponding to any specific smell was developed in the Faculties of Science ...

Come here and be quiet!

Come here and be quiet!
2015-08-31
Researchers at the Babraham Institute have discovered a strong physical gene interaction network that is responsible for holding genes in a silencing grip during early development. In the same way that people can interact with others in close proximity, say within the same room, or others millions of miles apart, there are also short- and long-range interactions within the genome forming a three-dimensional configuration where different parts of the genome come into contact with each other. The research, reported online in Nature Genetics, presents how key decision-making ...

Examining service delivery, patient outcomes in Ryan White HIV/AIDS Program

2015-08-31
Outpatient human immunodeficiency virus (HIV) health care facilities funded by the federal Ryan White HIV/AIDS Program (RWHAP) were more likely to provide case management, mental health, substance abuse and other support services than those facilities not funded by the program, according to an article published online by JAMA Internal Medicine. RWHAP was established in 1990 to provide funds to states, metropolitan areas and clinics to increase access to high-quality HIV care and treatment for low-income, uninsured and underinsured individuals and families affected by ...

Religion, physicians and surrogate decision-makers in the intensive care unit

2015-08-31
Religious or spiritual considerations were discussed in 16 percent of family meetings in intensive care units and health care professionals only rarely explored the patient's or family's religious or spiritual ideas, according to an article published online by JAMA Internal Medicine. Understanding how frequently discussions of spiritual concerns take place - and what characterizes them - is a first step toward clarity regarding best practices of responding to spiritual concerns in advanced illness. Douglas B. White, M.D., M.A.S., of the University of Pittsburgh School ...

Exclusive breastfeeding and the effect on postpartum multiple sclerosis relapses

2015-08-31
Women with multiple sclerosis (MS) who intended to breastfeed their infants exclusively for two months had a lower risk of relapse during the first six months after giving birth compared with women who did not breastfeed exclusively , according to an article published online by JAMA Neurology. About 20 percent to 30 percent of women with MS experience a relapse within the first three to four months after giving birth and there are no interventions for effective prevention of postpartum relapse. The effect of exclusive breastfeeding on postpartum risk of MS relapse is ...

Epigenomic changes are key to innate immunological memory

2015-08-31
It was long believed that acquired immunity--a type of immunity mediated by T- and B-cells--had memory, meaning that it could learn from new pathogens, making subsequent reactions more effective, whereas innate immunity--which is mediated by macrophages and other types of cells that react to certain molecules typically associated with pathogens--did not. However, it gradually became clear that things were not so simple. Plants and insects, which only have innate immunity, also seem to have immunological memory. Further, it has been reported that herpes virus infection increases ...

'Eat me' signal whets appetites for tumor-devouring dendritic cells

2015-08-31
By changing the mouse model they use to study how the immune system responds to cancer, a team of researchers hopes to shift the focus for one emerging form of cancer immunotherapy back to the standard approach--relying on antigen-presenting dendritic cells--and away from the current upstart, macrophages. Although macrophages, like dendritic cells, also take up antigens, they are more likely to degrade them than present them to T cells. The recent emphasis on macrophages stems, in part, from promising, but problematic, efforts to develop an effective macrophage-driven ...

CNIO scientists propose attacking bioenergetic metabolism to improve anti-cancer therapies

CNIO scientists propose attacking bioenergetic metabolism to improve anti-cancer therapies
2015-08-31
Cancer cells become addicted to glucose, which they use as their regular source of energy to grow and develop. Although this was observed over nine decades ago by the German physiologist, Otto Warburg; there is still not therapeutic strategy today that can effectively take advantage of this special energy requirement. The initial approach appears to be simple: the lack of glucose could specifically induce the death of cancer cells. A new study by the Spanish National Cancer Research Centre Cell and Cancer Unit, headed by the Cell Division and Cancer group of the Spanish ...

DNA-guided 3-D printing of human tissue is unveiled

2015-08-31
A UCSF-led team has developed a technique to build tiny models of human tissues, called organoids, more precisely than ever before using a process that turns human cells into a biological equivalent of LEGO bricks. These mini-tissues in a dish can be used to study how particular structural features of tissue affect normal growth or go awry in cancer. They could be used for therapeutic drug screening and to help teach researchers how to grow whole human organs. The new technique -- called DNA Programmed Assembly of Cells (DPAC) and reported in the journal Nature Methods ...

Closer to a treatment for the 'asthma of the esophagus'

2015-08-31
Scientists from the D'Or Institute of Research and Education (IDOR), the Federal University of Rio de Janeiro (UFRJ) and the Yale University School of Medicine have elucidated the chemical process behind a mysterious gastrointestinal disease that is becoming more frequent every day: the eosinophilic esophagitis (EoE), also known as the "asthma of the esophagus". The researchers identified a molecule which plays a key role in this condition and that can be a target in a new therapeutic strategy. The eosinophilic esophagitis is a chronic inflammatory disorder of the esophagus. ...

The 5-colour nutritional labelling system is the most effective for consumers

2015-08-31
While the French High Council for Public Health (HCSP) made public on Monday, 24 August 2015, a positive opinion regarding the relevance of the 5-colour code for the public, a team of researchers (Inserm/INRA/Paris 13 University) directed by Serge Hercberg, on publication of their article in the journal Nutrients, demonstrated that the 5-colour nutrition label (5-CNL) is the most effective nutritional information system for allowing consumers to recognise and compare the nutritional quality of foods, including "at-risk" populations (older subjects, those with a lower educational ...

Preventive medicine experts speak out about reducing firearm violence

2015-08-31
Amsterdam, NL, August 31, 2015 -- Every week in the U.S. an average of 645 people lose their lives to firearm violence and 1,565 more are treated in an emergency department for a firearm-related injury. Most of these events do not make headlines, but they account for about 7% of the premature deaths before age 65 in the U.S. In a special issue of Preventive Medicine, preventive medicine and health policy experts address a wide range of critical topics related to firearm violence, from the interaction of alcohol abuse with gun violence, effects of changes to gun laws in ...
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