Surgeons at The Children's Hospital of Philadelphia (CHOP) joined with colleagues from Penn Medicine recently to complete the world's first bilateral hand transplant on a child. Earlier this month, the surgical team successfully transplanted donor hands and forearms onto eight-year-old Zion Harvey who, several years earlier, had undergone amputation of his hands and feet and a kidney transplant following a serious infection. Led by L. Scott Levin, M.D., FACS*, Chairman of the Department of Orthopaedic Surgery at Penn Medicine, Director of the Hand Transplantation Program ...

Whether online auctions are selling rare Pokemon cards or fine art, the science behind inciting the highest bids gets a boost from a paper to be published in the September issue of the Journal of Retailing. Researchers from Germany and Australia teamed up to explore how bidders' emotions are affected by different types of auctions and how those emotions affect their bidding. In "Auction Fever! How Time Pressure and Social Competition Affect Bidders' Arousal and Bids in Retail Auctions," the three authors - Marc T.P. Adam of the University of Newcastle, Professor ...

PHILADELPHIA - Whether you're a human, a mouse, or even a fruitfly, losing sleep is a bad thing, leading to physiological effects and behavioral changes. One example that has been studied for many years is a link between sleep loss and aggression. But it can be difficult to distinguish sleep loss effects from stress responses, especially in rodent or human models. A team of researchers from the Perelman School of Medicine at the University of Pennsylvania used fruitflies to probe deeper into the cellular and molecular mechanisms that govern aggression and sleep. They ...

Pharmaceutical firms "underinvest" in long-term research to develop new cancer-fighting drugs due to the greater time and cost required to conduct such research, according to a newly published study co-authored by MIT economists. Specifically, drugs to treat late-stage cancers are less costly to develop than drugs for earlier-stage cancers, partly because the late-stage drugs extend people's lives for shorter durations of time. This means that the clinical trials for such drugs get wrapped up more quickly, too -- and provide drug manufacturers more time to control patented ...

Just as the brain forms memories of familiar faces, the immune system remembers pathogens it has encountered in the past. T cells with these memories circulate in the blood stream looking for sites of new infection. Recently, however, researchers have shown that memory T cells specific to viral infections can also set up residence in particular tissues. There, they stand guard, ready to respond quickly to the first sign of reinfection. Now, research led by a team from the University of Pennsylvania School of Veterinary Medicine shows that these resident memory T cells ...

July 28, 2015 - Eyes with central vision loss adapt by developing a new fixation point in a different part of the retina, called the preferred retinal location (PRL). Now for the first time, a new method makes it possible to identify PRLs in both eyes simultaneously, reports a study in the August issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer. The new eye-tracker technique may help in developing visual rehabilitation approaches to improve binocular vision for the many older adults ...

BEER-SHEVA, Israel...July 28, 2015 - Researchers at the Ben-Gurion University of the Negev (BGU) Cyber Security Research Center have discovered that virtually any cellphone infected with a malicious code can use GSM phone frequencies to steal critical information from infected "air-gapped" computers. Air-gapped computers are isolated -- separated both logically and physically from public networks -- ostensibly so that they cannot be hacked over the Internet or within company networks. Led by BGU Ph.D. student Mordechai Guri, the research team discovered how to turn ...

Consumers have access to multiple Web sites to search for online health information and can be far more involved in managing their own medical issues than ever before. However, this wealth of resources can make finding accurate information difficult, especially because it is often spread across multiple sites. A new study published in the Journal of Cognitive Engineering and Decision Making aims to evaluate the types of search strategies that Internet users adopt when trying to solve a complicated health problem. Joseph Sharit, a professor in the Department of Industrial ...

Alexandria, VA - The United States' Icebreaker Fleet - operated by the U.S. Coast Guard - consists of just two ships that are used for everything from search and rescue to national security operations to scientific research. In our August cover story, EARTH Magazine examines the various roles icebreakers play, especially in Arctic research, and how insufficient funding is affecting the icebreakers' roles. Icebreakers are becoming more important every year, as more commerce is conducted in Arctic regions as seasonal ice cover decreases. Yet over recent fiscal cycles, Congress ...

West Orange, NJ. July 28, 2015 Recommendations for improving clinical cognitive testing were reported by the American Academy of Neurology's (AAN) Behavioral Neurology Section (BNS) Group, led by Kirk R. Daffner, MD, of Boston, Mass. The Group focused on the Neurobehavioral Status Exam (NBSE), conducting evidence-based reviews of testing used for five domains - attention, language, memory, spatial cognition, and executive function). "Improving clinical cognitive testing" (doi: 10.1212/WNL.0000000000001763) was published online ahead of print on July 10, 2015, in Neurology, ...

Are the same regions and even the same cells of the brain area called hippocampus involved in encoding and retrieving memories or are different areas of this structure engaged? This question has kept neuroscientists busy for a long time. Researchers at the Mercator Research Group "Structure of Memory" at RUB have now found out that the same brain cells exhibit activity in both processes. They have published their results in the journal "Hippocampus". Hippocampus: the key to memory In the course of their project, Dr Nozomu Nakamura and Prof Dr Magdalena Sauvage from ...

Like to go your own way? Most of us actually prefer to follow the pack, according to UBC research. That's one of the outcomes from a study published in Evolution and Human Behavior that examines how mathematical models predict human behaviour. The research tested theories about when people should rely on "social information" - information that we learn vicariously from others - and when we should choose to go it alone. "People are conformist - and that's a good thing for cultural evolution," said Michael Muthukrishna, a Vanier and Liu Scholar and recent PhD recipient ...

More and more Americans on-the-go are skipping the "most important meal of the day," not eating until lunch. This tendency to miss breakfast has already been linked to the growing epidemic of obesity and cardiovascular problems in the US -- and it may put the health of diabetics at risk as well. Very little was known regarding the effect of skipping breakfast on the health of diabetics -- until now. A new Tel Aviv University study reveals the substantial impact of skipping breakfast on type-2 diabetics. "Fasting" until noon triggers major blood sugar spikes (postprandial ...

Amsterdam, July 28, 2015 - Policy makers need to take factors like geography, available skills and knowledge and the networks of local companies into account to boost the impact of higher education on economic development, according to a new Atlas Award-winning paper published in the International Journal of Educational Development. The authors of the study, from the University of Nottingham, say it's not quite as simple as more students equals higher income: higher education is key to economic development, but the way the two relate is complex, they say. "Of course ...

People with a common form of hearing loss not helped by hearing aids achieved significant and sometimes profound improvements in their hearing and understanding of speech with hybrid cochlear implant devices, according to a new multicenter study led by specialists at NYU Langone Medical Center. In the study, described online ahead of print in the journal The Laryngoscope July 7, researchers at 10 medical centers and private clinics in the United States implanted hybrid cochlear implants into one ear of 50 men and women. All study volunteers had badly damaged high-frequency, ...

The disposal and recycling of electronic devices has increased exposure to lead and other toxicants and created "an emerging health concern," according to a pediatrician who directs the Environmental Health and Lead Clinic at Cincinnati Children's Hospital Medical Center. In a recent Morbidity and Mortality Weekly Report, published by the Centers for Disease Control, Dr. Nick Newman reports on two children, ages 1 and 2, whose father worked at an e-scrap recycling company crushing cathode ray tubes (CRTs). CRTs, made from leaded glass, were commonly used in televisions ...

TAMPA, Fla. - The Lesbian, Gay, Bisexual, Transgender/Transsexual, Queer/Questioning (LGBTQ) community is a growing and medically-underserved minority population in the United States, with 3 to 12 percent of the population estimated to identify as LGBTQ. Moffitt Cancer Center researchers published one of the first articles that describe the current knowledge about cancers that may disproportionately affect the LGBTQ community, and also offered suggestions for improving their healthcare. LGBTQ community deals with significant economic and health disparities. Gay and lesbian ...

Chicago - Chronic back and leg pain sufferers in search of better pain relief options may have a new choice. According to a study published in the Online First edition of Anesthesiology, the official medical journal of the American Society of Anesthesiologists® (ASA®), patients who received a novel high frequency form of spinal cord stimulation (SCS) therapy experienced significantly greater, long-term relief for both chronic back and leg pain, when compared to a traditional low frequency form of SCS therapy. "This is the first long-term study to compare the ...

This news release is available in French. How do you get to Carnegie Hall? New research on the brain's capacity to learn suggests there's more to it than the adage that "practise makes perfect." A music-training study by scientists at the Montreal Neurological Institute and Hospital -The Neuro, at McGill University and colleagues in Germany found evidence to distinguish the parts of the brain that account for individual talent from the parts that are activated through training. The research involved brain imaging studies of 15 young adults with little or no musical ...

Philadelphia, PA, July 28, 2015 - Depression is a leading cause of disability worldwide, and treatment-resistant symptoms of depression have a terrible personal and societal cost. They can devastate lives, careers, and families. Some severely ill patients may be unable to attend to even the basic elements of self-care, while others attempt or complete suicide. Because of the clinical urgency, deep brain stimulation (DBS) treatments for depression have been developed over the past 15 years. These treatments require surgery to make a small hole in the skull through which ...

AUSTIN, Texas -- Hormones play a two-part role in encouraging and reinforcing cheating and other unethical behavior, according to research from Harvard University and The University of Texas at Austin. With cheating scandals a persistent threat on college campuses and financial fraud costing businesses more than $3.7 trillion annually, UT Austin and Harvard researchers looked to hormones for more answers, specifically the reproductive hormone testosterone and the stress hormone cortisol. According to the study, the endocrine system plays a dual role in unethical acts. ...

The ability to engage in mental time travel -- to delve back into past events or imagine future outcomes -- is a unique and central part of the human experience. And yet this very ability can have detrimental consequences for both physical and mental well-being when it becomes repetitive and uncontrolled. A special series of articles in the July 2015 issue of Clinical Psychological Science (CPS) investigates this kind of repetitive thinking, exploring the core psychological processes that underlie maladaptive thought processes like worry and rumination. The series highlights ...

TAMPA, Fla. - Cancer therapy has evolved from a "one-size-fits-all" type of treatment plan to a personalized approach based on a patient's type of cancer, the protein and genetic markers found in their tumors and their response to therapy. Important aspects of the personalized approach are pharmacogenomic studies that analyze associations between genetic variations and patient drug responses. Moffitt Cancer Center researchers have published a study in the Journal of the National Cancer Institute that analyzed the participation rate of patients in pharmacogenomic trials. ...

CAMBRIDGE, Mass.-- Making Caring Common (MCC), a project of the Harvard Graduate School of Education, today released new research that suggests that many teen boys and teen girls--and some of their parents--have biases against teen girls as leaders. These biases could be powerful barriers to leadership for a generation of teen girls with historically high levels of education who are key to closing our nation's gender gap in leadership. The report also suggests that much can be done to prevent and reduce gender biases in children. Titled "Leaning Out: Teen Girls and Gender ...

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have elucidated at the molecular level how an otherwise innocuous inherited mutation that is quite common in European populations interacts with a spontaneous somatic mutation to promote the development of Ewing's sarcoma. Ewing's sarcoma is an aggressive bone cancer that occurs primarily in children, adolescents and young adults. The tumor cells are characterized by a single spontaneous 'driver mutation', which results in formation of the oncogenic fusion gene EWSR1-FLI1. Its protein product EWSR1-FLI1, ...