WASHINGTON, D.C., September 16, 2014 --The emerging field of molecular electronics could take our definition of portable to the next level, enabling the construction of tiny circuits from molecular components. In these highly efficient devices, individual molecules would take on the roles currently played by comparatively-bulky wires, resistors and transistors. A team of researchers from five Japanese and Taiwanese universities has identified a potential candidate for use in small-scale electronics: a molecule called picene. In a paper published September 16 in The Journal ...

San Francisco, September 15, 2014— For patients with locally advanced pancreatic cancer, the combination of chemotherapy and stereotactic ablative radiation (SABR) may be a promising treatment option, ultimately allowing them to undergo surgery that may not otherwise be an option, according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 56th Annual Meeting. Surgery is the only potentially curative therapy for individuals with pancreatic ductal adenocarcinoma (PDA), the most common type of pancreatic cancer. However, pancreatic cancer ...

This news release is available in French. Montreal, September 16, 2014 — Impossible deadlines, demanding bosses, abusive colleagues, unpaid overtime — all these factors can lead to a burnout. When it comes to mental health in the workplace, we often forget to consider the influence of home life. That's about to change, thanks to new research from Concordia University and the University of Montreal, which proves that having an understanding partner is just as important as having a supportive boss. The study, published in the journal Social Psychiatry and Psychiatric ...

September 16, 2014 -- While abnormalities in the adrenergic and noradrenergic systems, both integral in the fight-or-flight response, are thought to play a role in the development of post-traumatic stress disorder (PTSD), until now there has been no genetic evidence of this connection. A collaborative study just released by researchers at Columbia University's Mailman School of Public Health and the University of Michigan found an interaction between the ADRB2 gene and childhood adversity. For individuals with two or more experiences of childhood trauma, such as abuse, ...

We have all seen a peacock show its extravagant, colorful tail feathers in courtship of a peahen. Now, a group of researchers have used a special camera developed by an engineer at Washington University in St. Louis to discover that female northern swordtail fish choose their mates based on a similar display. Marine biologists at the University of Texas at Austin used a bioinspired polarization camera developed by Viktor Gruev, PhD, associate professor of computer science & engineering at Washington University, to make the discovery. His camera has been used in other ...

A mathematical model that replicates Ebola outbreaks can no longer be used to ascertain the eventual scale of the current epidemic, finds research conducted by the University of Warwick. Dr Thomas House, of the University's Warwick Mathematics Institute, developed a model that incorporated data from past outbreaks that successfully replicated their eventual scale. The research, titled Epidemiological Dynamics of Ebola Outbreaks and published by eLife, shows that when applying the available data from the ongoing 2014 outbreak to the model that it is, according to Dr ...

Philadelphia, PA, September 16, 2014 – Schizophrenia is associated with increased rates and intensity of tobacco smoking. A growing body of research suggests that the relationship between schizophrenia and smoking stems, in part, from an effort by patients to use nicotine to self-medicate symptoms and cognitive impairment associated with the disease. A new study, published in the current issue of Biological Psychiatry, sheds light on this hypothesis. The authors found that the level of nicotine receptors in the brain was lower in schizophrenia patients than in a matched ...

Scientists make discoveries everyday, but that doesn't mean the findings are put into common practice. In India, for example, the neonatal mortality rate is 10 times higher than in the developed world. While clinical trials found that applying an inexpensive topical solution of chlorhexidine to cleanse a newborn's umbilical cord reduced the neonatal mortality rate by 24 percent, many Indian parents did not receive or follow this information. "The challenge is not that we don't have solutions to solve major societal problems, but that we struggle with how to take a ...

A team of NOAA researchers today confirmed the discovery just outside San Francisco's Golden Gate strait of the 1910 shipwreck SS Selja and an unidentified early steam tugboat wreck tagged the "mystery wreck." The researchers also located the 1863 wreck of the clipper ship Noonday, currently obscured by mud and silt on the ocean floor. These and other shipwreck investigations mark the first mission of a two-year project to locate, identify and better understand some of the estimated 300 wrecks in Gulf of the Farallones National Marine Sanctuary, and the adjacent Golden ...

This news release is available in French. Dairy is considered part of a healthy diet and dietary guidelines recommend the daily consumption of 2-4 portions of milk-based products such as milk, yogurt, cheese, cream and butter. It's well known that dairy products contain calcium and minerals good for bones, but new research has shown that dairy consumption may also have beneficial effects on metabolic health and can reduce risk of metabolic diseases such as obesity and type 2 diabetes. Curious about these impacts, researchers from CHU de Québec Research Center ...

An experimental positron emission tomography (PET) tracer is effective in diagnosing concussion-related brain disease while a person is still alive, according to a case study conducted at the Icahn School of Medicine at Mount Sinai, and at Molecular Neuroimaging (MNI) LLC in New Haven, and published September 16 in the journal Translational Psychiatry. Specifically, the study results suggest that an experimental radiolabeled compound called [18 F]-T807, which is designed to latch onto a protein called tau that accumulates in the brain with repetitive blows to the head, ...

(Boston) — Women who have had children (parous women) appear to have an increased risk of developing estrogen receptor-negative breast cancer, the subtype that carries a higher mortality rate and is more common in women of African ancestry. A similar relationship was found for triple-negative breast cancer. However, the association between childbearing and increased risk of estrogen receptor-negative and triple-negative breast cancer was largely confined to the women who had never breastfed. These findings, published in the Journal of the National Cancer Institute, suggest ...

San Francisco, September 16, 2014—A large, international analysis of patients with stage IV non-small cell lung cancer (NSCLC) indicates that a patient's overall survival (OS) rate can be related to factors including the timing of when metastases develop and lymph node involvement, and that aggressive treatment for "low-risk" patients leads to a five-year OS rate of 47.8 percent, according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 56th Annual Meeting. When lung cancer has spread from an original tumor to other sites of the ...

Scientists could soon better predict a man's risk of getting prostate cancer after a worldwide team of researchers carried out the largest-ever analysis of the cancer's genetic biomarkers, reported in Nature Genetics today. QUT Institute of Health and Biomedical Innovation's Dr Jyotsna Batra and Distinguished Professor Judith Clements, who led the Australian researchers in the large consortia of research hubs around the world, said the teams analysed more than 10 million genetic markers in 80,000 men. "It's the largest analysis of genetic biomarkers ever done. We found ...

Researchers at the Hebrew University of Jerusalem have developed a new cocktail that is highly effective at coaxing adult cells to become quality pluripotent stem cells. Regenerative medicine is a new and expanding area that aims to replace lost or damaged cells, tissues or organs through cellular transplantation. Because stem cells derived from human embryos can trigger ethical concerns, a good solution is reprogramming adult cells back to an embryo-like state using a combination of reprogramming factors. The resulting cells, called induced pluripotent stem cells ...

San Francisco, September 16, 2014— Non-small cell lung cancer (NSCLC) survivors who never smoked or who are former smokers at the time of diagnosis have a lower risk of developing secondary primary lung cancers (SPLC) compared to those who are current smokers, suggesting that increased tobacco exposure is associated with a higher risk of SPLC, according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 56th Annual Meeting. The analysis studied the association between patients' smoking histories and their risks of developing SPLC, which ...

Size is relative, especially to people who tend to be on the heavy side. Researchers at the Columbia University Medical Center in the US found that seven in every ten obese adults underestimate how much someone weighs. People of normal weight make this mistake much less often. Mothers of overweight or obese children also tend to misjudge their children's size, as youngsters misjudge their obese mothers' size, says lead author Tracy Paul, now at Weill-Cornell Medical College, in a study¹ in the Journal of General Internal Medicine², published by Springer. If abnormal weight ...

San Francisco, September 15, 2014—Prostate cancer patients who received hypofractionated (HPFX) radiation therapy (RT) reported that their quality of life, as well as bladder and bowel function were at similar levels before and after RT, according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 56th Annual Meeting. Additionally, results indicate that parallel quality of life outcomes occurred between groups of patients who receive different regimens of HPFX RT. The phase I/II trial enrolled 343 patients with low-to-intermediate risk ...

San Francisco, September 15, 2014—A comparison of five-year sexual function outcomes, as reported by patients treated with external beam radiotherapy (EBRT) versus combination EBRT plus brachytherapy, indicates that the utilization of vessel-sparing radiation therapy makes cure possible without compromising long-term sexual function, according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 56th Annual Meeting. The study examined the patient-reported outcomes of 91 men with prostate cancer who received MRI-guided, vessel-sparing ...

Approval of the Keystone XL pipeline (KXL) would likely increase oil sands extraction, according to 26 oil sands professionals and researchers surveyed by the non-profit organization Near Zero. The results are detailed in the report, "Keystone XL: The Climate Impact," and includes both supporters and opponents of the pipeline. This additional extraction of oil sands could lead to significantly higher greenhouse gas emissions, with the exact amount depending largely on how markets respond. "This report examines three main scenarios discussed by participants in our ...

San Francisco, September 15, 2014—A prospective study that compared patient-reported outcomes of a broad set of cancer patients with bone metastases demonstrates that single fraction radiation therapy (SFRT) is equally as effective as multiple fraction radiation therapy (MFRT) when pain, function and quality of life are considered, according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 56th Annual Meeting. The multi-center study indicates that improvements in patients' pain, function and degree of distress were similar between the ...

EUGENE, Ore. -- Each tree species has its own bacterial identity. That's the conclusion of University of Oregon researchers and colleagues from other institutions who studied the genetic fingerprints of bacteria on 57 species of trees growing on a Panamanian island. "This study demonstrates for the first time that host plants from different plant families and with different ecological strategies possess very different microbial communities on their leaves," said lead author Steven W. Kembel, a former postdoctoral researcher in the UO's Institute of Ecology and Evolution ...

Molecular mechanisms of the Krüppel-like family of transcription factors (KLFs) have been studied more in proliferating cells than in post-mitotic cells such as neurons. Prof. Jeffrey L. Goldberg who comes from University of California San Diego, USA and his team recently found that KLFs regulate intrinsic axon growth ability in central nervous system (CNS) neurons including retinal ganglion cells, and hippocampal and cortical neurons. With at least 15 of 17 KLF family members expressed in neurons and at least 5 structurally unique subfamilies, it is important to ...

There is currently no standard pharmacological treatment for spinal cord injury. Here, Dr. Florencia Labombarda, who comes from Buenos Aires University, Argentina suggests that progesterone, a steroid hormone, may be a promising therapeutical candidate as it is already for traumatic brain injury, where it has reached phase II clinical trials. We rely on previous works showing anti-inflammatory, neuroprotective and promyelinating roles for progesterone after spinal cord injury and in our recent paper, in which we demonstrate that progesterone diminishes lesion, preserves ...

Oxidative stress is closely associated with secondary cell death in many disorders of the central nervous system including stroke, Parkinson's disease, Alzheimer's disease. Among many aberrant oxidative stress-associated proteins, DJ-1 has been associated with the oxidative stress cell death cascade primarily in Parkinson's disease. Although principally expressed in the cytoplasm and nucleus, DJ-1 can be secreted into the serum under pathological condition. Recently, a close pathological association between DJ-1 and oxidative stress in stroke has been implicated. To this ...