Cilia, the cell's tails and antennas, are among the most important biological structures. They line our windpipe and sweep away all the junk we inhale; they help us see, smell and reproduce. When a mutation disrupts the function or structure of cilia, the effects on the human body are devastating and sometimes lethal. The challenge in diagnosing, studying and treating these genetic disorders, called ciliopathies, is the small size of cilia -- about 500-times thinner than a piece of paper. It's been difficult to examine them in molecular detail until now. Professor ...

COLUMBIA, Mo. - A new study from University of Missouri and Virginia Tech researchers is challenging accepted ideas about how ancient soft-bodied organisms become part of the fossil record. Findings suggest that bacteria involved in the decay of those organisms play an active role in how fossils are formed--often in a matter of just a few tens to hundreds of years. Understanding the relationship between decay and fossilization will inform future study and help researchers interpret fossils in a new way. "The vast majority of the fossil record is composed of bones and ...

New Rochelle, NY, December 18, 2014--Internet addiction is an impulse-control problem marked by an inability to inhibit Internet use, which can adversely affect a person's life, including their health and interpersonal relationships. The prevalence of Internet addiction varies among regions around the world, as shown by data from more than 89,000 individuals in 31 countries analyzed for a study published in Cyberpsychology, Behavior, and Social Networking, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Cyberpsychology, ...

Health care systems and providers are not attuned to older adults' malnutrition risk, and ignoring malnutrition exacts a toll on hospitals, patients, and payers, according to the latest issue of the What's Hot newsletter from The Gerontological Society of America (GSA). Under the title "Aging Policy: Preventing and Treating Malnutrition to Improve Health and Reduce Costs," the new installment points out that aging is a risk factor for malnutrition and highlights opportunities to improve nutrition awareness, interventions, and policy priorities. Support for the publication ...

To paraphrase Mark Twain, the report of the Kepler spacecraft's death was greatly exaggerated. Despite a malfunction that ended its primary mission in May 2013, Kepler is still alive and working. The evidence comes from the discovery of a new super-Earth using data collected during Kepler's "second life." "Like a phoenix rising from the ashes, Kepler has been reborn and is continuing to make discoveries. Even better, the planet it found is ripe for follow-up studies," says lead author Andrew Vanderburg of the Harvard-Smithsonian Center for Astrophysics (CfA). NASA's ...

New Rochelle, NY, December 18, 2014--Pretreatment of cellulosic biomass using cell wall degrading enzymes is a critical step in the release of sugars needed to produce biofuels and renewable, biobased chemicals and materials. A new study that demonstrates and quantifies the impact of enzymatic hydrolysis and drying on the nanostructure and available reaction volume of pretreated hardwoods and switchgrass is published in Industrial Biotechnology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Industrial Biotechnology website ...

PHILADELPHIA - Type 1 diabetes (T1D) patients who have developed low blood sugar (hypoglycemia) as a complication of insulin treatments over time are able to regain normal internal recognition of the condition after receiving pancreatic islet cell transplantation, according to a new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania, published online in Diabetes. Severe hypoglycemia--a life-threatening complication of insulin treatment for T1D--can occur when the body's defense mechanisms against low blood sugar are broken down ...

Detroit- A Wayne State University interdisciplinary research team in the Eugene Applebaum College of Pharmacy and Health Sciences has made a surprising discovery: older, more mature motorists -- who typically are better drivers in many circumstances -- are much worse than their younger counterparts when texting while driving. Currently published online and scheduled to be published in print in the January 2015 issue of Accident Analysis and Prevention, the study "The Effects of Texting on Driving Performance in a Driving Simulator: The Influence of Driver Age" explores ...

Many of the worst West Coast winter floods pack a double punch. Heavy rains and melting snow wash down the mountains together to breach riverbanks, wash out roads and flood buildings. These events are unpredictable and difficult to forecast. Yet they will become more common as the planet warms and more winter precipitation falls as rain rather than snow. University of Washington mountain hydrology experts are using the physics behind these events to better predict the risks. "One of the main misconceptions is that either the rain falls and washes the snow away, or that ...

HEIDELBERG, 18 December 2014 - The quality of the colon mucus in mice depends on the composition of gut microbiota, reports a Swedish-Norwegian team of researchers from the University of Gothenburg and the Norwegian University of Life Sciences in Oslo. The work, published in EMBO reports, suggests that bacteria in the gut affect mucus barrier properties in ways that can have implications for health and disease. "Genetically similar mice with subtle but stable and transmissible intestinal microbiota showed unexpectedly large differences in the inner colon mucus layer. ...

Eating bilberries diminishes the adverse effects of a high-fat diet, according to a recent study at the University of Eastern Finland. For the first time, bilberries were shown to have beneficial effects on both blood pressure and nutrition-derived inflammatory responses. Low-grade inflammation and elevated blood pressure are often associated with obesity-related diseases. The study focused on the health effects of bilberries on mice that were fed high-fat diet for a period of three months. Some of the mice were fed either 5% or 10% of freeze-dried bilberries in the diet. ...

The enzyme telomerase repairs cell damage produced by ageing, and has been used successfully in therapies to lengthen the life of mice. Now it has been observed that it could also be used to cure illnesses related to the ageing process. Researchers at the Spanish National Cancer Research Centre (CNIO) have for the first time treated myocardial infarction with telomerase by designing a very innovative strategy: a gene therapy that reactivates the telomerase gene only in the heart of adult mice, thus increasing survival rates in those animals by 17 % following a heart attack. Christian ...

Researchers from North Carolina State University have found a way of binding peptides to the surface of gallium nitride (GaN) in a way that keeps the peptides stable even when exposed to water and radiation. The discovery moves researchers one step closer to developing a new range of biosensors for use in medical and biological research applications. GaN is a biocompatible material that fluoresces, or lights up, when exposed to radiation. Researchers are interested in taking advantage of this characteristic to make biosensors that can sense specific molecules, or "analytes," ...

This news release is available in German. Physicists are continuously advancing the control they can exert over matter. A German-Spanish team working with researchers from the Max Planck Institute for Nuclear Physics in Heidelberg has now become the first to image the motion of the two electrons in a helium atom and even to control this electronic partner dance. The scientists are succeeding in this task with the aid of different laser pulses which they timed very accurately with respect to each other. They employed a combination of visible flashes of light and ...

Trophoblasts, cells that form an outer layer around a fertilized egg and develop into the major part of the placenta, have now been shown to respond to inflammatory danger signals, researchers from Norwegian University of Science and Technology (NTNU) found in a recent study published in Journal of Reproductive Immunology December 2014. The researchers said their findings were an important step in understanding how inflammatory responses in the placenta can contribute to the development of pregnancy disorders such as preeclampsia. The trophoblast inflammatory response ...

This news release is available in German. Puebla del Guzman (Andalusia) / Magdeburg. Being part of the mining area Herrerias in Andalusia, deep waters of Pit Lake Guadiana show extremely high concentration of dissolved carbon dioxide (CO2). In the case of a spontaneous ebullition, human beings close-by would be jeopardized. To demonstrate the danger and the possible solution, scientists of the Spanish Institute of Geology and Mining, the University of the Basque Country (UPV/EHU, Bilbao) and the Helmholtz Centre for Environmental Research (UFZ) constructed a pilot ...

Chlorine is a common disinfectant that is used to kill bacteria, for example in swimming pools and drinking water supplies. Our immune system also produces chlorine, which causes proteins in bacteria to lose their natural folding. These unfolded proteins then begin to clump and lose their function. RUB researchers headed by Prof Dr Lars Leichert have discovered a protein in the intestinal bacterium E. coli that protects bacteria from chlorine. In the presence of chlorine, it tightly bonds with other proteins, thus preventing them from coagulating. Once the danger has passed, ...

This news release is available in German. A team of scientists headed by Dr. Florian Bassermann at the III. Medizinische Klinik, TUM Klinikum rechts der Isar, has been investigating mantle cell lymphoma, a subgroup of non-Hodgkin's lymphoma, which, despite new therapies, has poor patient survival rates. "Programmed cell death no longer functions in many lymphoma cells. This causes them to multiply uncontrollably. We urgently need to find out what's going wrong in these cells in order to find new treatment therapies," explains Bassermann. The scientists started analyzing ...

A new study shows that many patients infected with the hepatitis C virus (HCV) are lost during different stages of health care to manage the disease. This real-life' view of the HCV patient care continuum in a major U.S. urban area is published in Hepatology, a journal of the American Association for the Study of Liver Diseases, and highlights the importance of generating awareness among clinicians and at-risk groups about appropriate HCV testing, referral, support and care. Despite efforts to manage HCV, it is one of the most prevalent diseases with up to 150 million ...

Hydrogen peroxide (H2O2) is a strong oxidizer and is used as a bleaching agent for hair and teeth, and as a wound disinfectant. In addition, H2O2 also forms in the body, for example as a metabolic product of cellular respiration. It belongs to a group of chemicals called reactive oxygen species (ROS), which scientists suspect to have a damaging effect on cells and their components. For example, they are believed to play a role in carcinogenesis, degenerative diseases, and even aging. Body cells contain large quantities of enzymes called peroxiredoxins that degrade H2O2 ...

Research that provides a new understanding as to why ferrets are similar to humans is set to have major implications for the development of novel drugs and treatment strategies. Published in the prestigious journal Nature Communications, the research is a collaboration between Professor Michael Jennings and other researchers from the Institute for Glycomics, Griffith University and collaborators at the University of Queensland and the University of Adelaide. The team has shown for the first time that ferrets share a mutation that was previously thought to be unique ...

ANN ARBOR--In a development that could lead to a deeper understanding of cancer and better early-stage treatment of the disease, University of Michigan researchers have devised a reliable way to grow a certain type of cancer cells from patients outside the body for study. The new technique is more than three times as effective as previous methods. Researchers say it's a major step forward in the study of circulating tumor cells, which are shed from tumors and circulate through the blood of cancer patients. They're believed to cause metastasis, the spread of cancer ...

SAN FRANCISCO--The Greenland Ice Sheet is ready for its close-up. The highest-resolution satellite images ever taken of that region are making their debut. And while each individual pixel represents only one moment in time, taken together they show the ice sheet as a kind of living body--flowing, crumbling and melting out to sea. The Ohio State University has partnered with the Polar Geospatial Center at the University of Minnesota to turn images captured by DigitalGlobe's Worldview-1 and 2 satellites into publicly available elevation maps that researchers can use to ...

ANN ARBOR--Impending fatherhood can lower two hormones--testosterone and estradiol--for men, even before their babies are born, a new University of Michigan study found. Other studies indicate that men's hormones change once they become fathers, and there is some evidence that this is a function of a decline after the child's birth. The new U-M study is the first to show that the decline may begin even earlier, during the transition to fatherhood, said Robin Edelstein, the study's lead author. "We don't yet know exactly why men's hormones are changing," said Edelstein, ...

LONDON, UK (18 December 2014)--A new study released today presents powerful evidence that clearing trees not only spews carbon into the atmosphere, but also triggers major shifts in rainfall and increased temperatures worldwide that are just as potent as those caused by current carbon pollution. Further, the study finds that future agricultural productivity across the globe is at risk from deforestation-induced warming and altered rainfall patterns. The report, "Effects of Tropical Deforestation on Climate Change and Agriculture," published today in Nature Climate Change ...