Stepping on the scale is common among dieters but how does the frequency of weigh-ins impact weight? A new study in PLOS ONE showed that the more frequently dieters weighed themselves the more weight they lost, and if participants went more than a week without weighing themselves, they gained weight. The researchers analyzed 2,838 weight measurements (up to a years' worth of weigh-ins) from 40 overweight individuals (with a body mass index of 25 and over) who indicated that weight loss was a personal goal or concern. The researchers found that weight loss was related ...

DENVER - Next generation sequencing in malignant pleural mesothelioma (MPM) tumors shows a complex mutational setting with a high number of genetic alterations in genes involved in DNA repair, cell survival and cell proliferation pathways. Increased accumulation of mutations correlates with early progression of the tumor and decreased survival. MPM is a fatal cancer associated with asbestos exposure that develops on the outer linings of the lungs. The 3-year survival rate is only 8% and most MPM patients are diagnosed with late stage disease with limited therapeutic options. ...

DENVER - A prospective nationwide survey on perceptions of lung cancer in the general population of France highlights a need for increased public education on the benefits of lung cancer screening, the good survival rates of early-stage disease and the improved outcomes with new therapeutic strategies, including targeted-therapies. Lung cancer management in recent years has improved patient outcomes because of screening, improved surgery and radiotherapy in early and locally-advanced stages of disease, new chemotherapies, validated maintenance therapy, and effective targeted ...

High-energy jets powered by supermassive black holes can blast away a galaxy's star-forming fuel, resulting in so-called "red and dead" galaxies: those brimming with ancient red stars yet containing little or no hydrogen gas to create new ones. Now astronomers using the Atacama Large Millimeter/submillimeter Array (ALMA) have discovered that black holes don't have to be nearly so powerful to shut down star formation. By observing the dust and gas at the center of NGC 1266, a nearby lenticular galaxy with a relatively modest central black hole, the astronomers have detected ...

BELLINGHAM, Washington, USA - The first issue of the new Journal of Astronomical Telescopes, Instruments, and Systems (JATIS) has been launched by SPIE, the international society for optics and photonics. All articles will be freely available through the end of 2015 in the SPIE Digital Library. Mark Clampin, SPIE Fellow and James Webb Space Telescope Observatory Project Scientist at NASA Goddard Space Flight Center, is editor-in-chief. "A key motivation for the creation of this journal has been the continuing success of SPIE's Instrumentation in Astronomy conference ...

VIDEO: The Arctic Ocean is absorbing more of the sun's energy in recent years as white, reflective sea ice melts and darker ocean waters are exposed. The increased darker surface area... Click here for more information. NASA satellite instruments have observed a marked increase in solar radiation absorbed in the Arctic since the year 2000 - a trend that aligns with the steady decrease in Arctic sea ice during the same period. While sea ice is mostly white and reflects the ...

Johns Hopkins researchers have developed a sugar-based molecular microcapsule that eliminates the toxicity of an anticancer agent developed a decade ago at Johns Hopkins, called 3-bromopyruvate, or 3BrPA, in studies of mice with implants of human pancreatic cancer tissue. The encapsulated drug packed a potent anticancer punch, stopping the progression of tumors in the mice, but without the usual toxic effects. "We developed 3BrPA to target a hallmark of cancer cells, namely their increased dependency on glucose compared with normal cells. But the nonencapsulated drug ...

In a development that holds promise for future magnetic memory and logic devices, researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and Cornell University successfully used an electric field to reverse the magnetization direction in a multiferroic spintronic device at room temperature. This demonstration, which runs counter to conventional scientific wisdom, points a new way towards spintronics and smaller, faster and cheaper ways of storing and processing data. "Our work shows that 180-degree magnetization switching ...

Premature ovarian failure, also known as primary ovarian insufficiency (POI), affects 1% of all women worldwide. In most cases, the exact cause of the condition, which is often associated with infertility, is difficult to determine. A new Tel Aviv University study throws a spotlight on a previously-unidentified cause of POI: a unique mutation in a gene called SYCE1 that has not been previously associated with POI in humans. The research, published in the Journal of Clinical Endocrinology and Metabolism, was led by Dr. Liat de Vries and Prof. Lina Basel-Vanagaite of TAU's ...

A new species of short-necked marine reptile from the Triassic period has been discovered in China, according to a study published December 17, 2014 in the open-access journal PLOS ONE by Xiao-hong Chen from Wuhan Centre of China Geological Survey and colleagues. Hupehsuchia is a group of mysterious Triassic marine reptiles which have, so far, only been found in two counties in Hubei Province, China. The group is known by its modestly long neck, with nine to ten cervical vertebrae, but the authors of this study recently discovered a new species of Hupehsuchia that may ...

A network of nine reference sites off the Australian coast is providing the latest physical, chemical, and biological information to help scientists better understand Australia's coastal seas, according to a study published December 17, 2014 in the open-access journal PLOS ONE by Tim Lynch from CSIRO, Australia and colleagues. Sustained oceanic observations allow scientists to track changes in oceanography and ecosystems. To address this, the Australian Integrated Marine Observing System (IMOS) implemented a network of nine National Reference Stations (NRS). The network ...

Like human patients, mice with a form of Duchenne muscular dystrophy undergo progressive muscle degeneration and accumulate connective tissue as they age. Now, researchers at the Stanford University School of Medicine have found that the fault may lie at least partly in the stem cells that surround the muscle fibers. They've found that during the course of the disease, the stem cells become less able to make new muscle and instead begin to express genes involved in the formation of connective tissue. Excess connective tissue -- a condition called fibrosis -- can accumulate ...

Bird migration is an impressive phenomenon, but why birds often travel huge distances to and from their breeding grounds in the far North is still very unclear. Suggestions include that the birds profit from longer daylight hours, or that there are fewer predators. Researchers from the University of Groningen and the NIOO-KNAW Vogeltrekstation, the Dutch centre for bird migration and demographics, have discovered a new explanation. They investigated barnacle geese breeding on Spitsbergen and compared them with birds of the same species that did not migrate but stayed ...

DURHAM, N.C. -- The best way to protect wild spinner dolphins in Hawaii while also maintaining the local tourism industry that depends on them is through a combination of federal regulations and community-based conservation measures, finds a new study from Duke University. Each year, hundreds of thousands of tourists to Hawaii pay to have up-close encounters with the animals, swimming with them in shallow bays the dolphins use as safe havens for daytime rest. But as the number of tours increases, so do the pressures they place on the resting dolphins. The Duke study ...

A new catalytic process is able to convert what was once considered biomass waste into lucrative chemical products that can be used in fragrances, flavorings or to create high-octane fuel for racecars and jets. A team of researchers from Purdue University's Center for Direct Catalytic Conversion of Biomass to Biofuels, or C3Bio, has developed a process that uses a chemical catalyst and heat to spur reactions that convert lignin into valuable chemical commodities. Lignin is a tough and highly complex molecule that gives the plant cell wall its rigid structure. Mahdi ...

A close look at the night sky reveals that stars don't like to be alone; instead, they congregate in clusters, in some cases containing as many as several million stars. Until recently, the oldest of these populous star clusters were considered well understood, with the stars in a single group having formed at different times, over periods of more than 300 million years. Yet new research published online today in the journal Nature suggests that the star formation in these clusters is more complex. Using data from the Hubble Space Telescope, a team of researchers at the ...

OAK RIDGE, Tenn., Dec. 17, 2014--Scientists at the Department of Energy's Oak Ridge National Laboratory have used advanced microscopy to carve out nanoscale designs on the surface of a new class of ionic polymer materials for the first time. The study provides new evidence that atomic force microscopy, or AFM, could be used to precisely fabricate materials needed for increasingly smaller devices. Polymerized ionic liquids have potential applications in technologies such as lithium batteries, transistors and solar cells because of their high ionic conductivity and unique ...

UCLA researchers have developed a lens-free microscope that can be used to detect the presence of cancer or other cell-level abnormalities with the same accuracy as larger and more expensive optical microscopes. The invention could lead to less expensive and more portable technology for performing common examinations of tissue, blood and other biomedical specimens. It may prove especially useful in remote areas and in cases where large numbers of samples need to be examined quickly. The microscope is the latest in a series of computational imaging and diagnostic devices ...

VIDEO: It's official -- our holiday lights are so bright we can see them from space. Thanks to the VIIRS instrument on the Suomi NPP satellite, a joint mission between NASA... Click here for more information. Even from space, holidays shine bright. With a new look at daily data from the NOAA/NASA Suomi National Polar-orbiting Partnership (Suomi NPP) satellite, a NASA scientist and colleagues have identified how patterns in nighttime light intensity change during major holiday ...

The sun emitted a mid-level solar flare, peaking at 11:50 p.m. EST on Dec. 16, 2014. NASA's Solar Dynamics Observatory, which watches the sun constantly, captured an image of the event. Solar flares are powerful bursts of radiation. Harmful radiation from a flare cannot pass through Earth's atmosphere to physically affect humans on the ground, however -- when intense enough -- they can disturb the atmosphere in the layer where GPS and communications signals travel. To see how this event may affect Earth, please visit NOAA's Space Weather Prediction Center at http://spaceweather.gov, ...

In the first real-world trial of the impact of patient-controlled access to electronic medical records, almost half of the patients who participated withheld clinically sensitive information in their medical records from some or all of their health care providers. This is the key finding of a new study by researchers from Clemson University, the Regenstrief Institute, Indiana University School of Medicine and Eskenazi Health published in the Journal of General Internal Medicine. Kelly Caine, assistant professor in Clemson's School of Computing, and colleagues at Clemson ...

A team of scientists, led by the University of Toronto's Barbara Sherwood Lollar, has mapped the location of hydrogen-rich waters found trapped kilometres beneath Earth's surface in rock fractures in Canada, South Africa and Scandinavia. Common in Precambrian Shield rocks - the oldest rocks on Earth - the ancient waters have a chemistry similar to that found near deep sea vents, suggesting these waters can support microbes living in isolation from the surface. The study, to be published in Nature on December 18, includes data from 19 different mine sites that were ...

Chemical modifications to DNA's packaging -- known as epigenetic changes -- can activate or repress genes involved in autism spectrum disorders (ASDs) and early brain development, according to a new study to be published in the journal Nature on Dec. 18. Biochemists from NYU Langone Medical Center found that these epigenetic changes in mice and laboratory experiments remove the blocking mechanism of a protein complex long known for gene suppression, and transitions the complex to a gene activating role instead. Researchers say their findings represent the first link ...

LA JOLLA, CA--December 17, 2014--Chemists at The Scripps Research Institute (TSRI) have invented a powerful method for joining complex organic molecules that is extraordinarily robust and can be used to make pharmaceuticals, fabrics, dyes, plastics and other materials previously inaccessible to chemists. "We are rewriting the rules for how one thinks about the reactivity of basic organic building blocks, and in doing so we're allowing chemists to venture where none has gone before," said Phil S. Baran, the Darlene Shiley Chair in Chemistry at TSRI, whose laboratory reports ...

Johns Hopkins and University of Alberta researchers have identified a single protein as the root of painful and dangerous allergic reactions to a range of medications and other substances. If a new drug can be found that targets the problematic protein, they say, it could help smooth treatment for patients with conditions ranging from prostate cancer to diabetes to HIV. Their results appear in the journal Nature on Dec. 17. Previous studies traced reactions such as pain, itching and rashes at the injection sites of many drugs to part of the immune system known as mast ...