Dysfunctional TGF-beta signaling contributes to Loeys-Dietz syndrome-associated aortic aneurysm Patients with the connective tissue disorder Loeys-Dietz syndrome (LDS) are at high risk for aortic aneurysm. LDS results in the presence of missense mutations ...

Evaluation of mangafodipir treatment for oxaliplatin-associated neuropathy An unfortunate side effect of the platinum-chemotherapy drug oxaliplatin is the development of neurotoxicity, which can adversely affect a patient's quality of life; therefore, ...

New research offers hope for vaccine and therapies for deadly infections LA BioMed researcher leads team that finds antibodies to protect against mucormycosis LOS ANGELES – (Dec. 20, 2013) – Mucormycosis ...

UBC-VCH scientists use drug to repair rare birth defect Success in mouse model is first instance of drug reversing a congenital deformity University of British Columbia and Vancouver Coastal Health scientists have developed a potential cure for a rare eye disease, ...

Enlisting cells' protein recycling machinery to regulate plant products New molecular tools for controlling production of compounds important for flavors, human health, and biofuels UPTON, NY--Scientists at the U.S. Department of Energy's Brookhaven ...

New mechanism that permits selective capture of microRNAs in nanovesicles that shuttle between cells The study presents the first description of a set of related nuceleotide sequences essential for the role of these small molecules in ...

More mentions in the FT linked to greater popularity of stocks A 6-year study of the Financial Times has found that the more frequently a company is mentioned in the newspaper in the morning, the greater the volume of shares traded in that company during the ...

Efforts to curb climate change require greater emphasis on livestock CORVALLIS, Ore. – While climate change negotiators struggle to agree on ways to reduce carbon dioxide (CO2) emissions, they have paid inadequate attention to other greenhouse gases associated ...

Birth of black hole kills the radio star Research clears telescope, disproves long-held theory Astronomers led by a Curtin University researcher have discovered a new population of exploding stars that "switch off" their radio transmissions before collapsing ...

An earthquake or a snow avalanche has its own shape However, it is crucial what one observes – paper fracture or the avalanching of snow. The results were just published in the Nature Communications journal. Avalanches of snow or earthquakes can be described in other ...

Smooth or grainy? A SISSA paper reviews research on the grain of space-time Smooth" or grainy? Is space-time continuous or is it made up of very fine (10-35 metres on the "Planck scale") but discrete grains, if we look at it very ...

IRB develops ChroGPS, a new generation visual browser of the epigenome This is a software application that provides easily interpretable maps from which to analyse and understand the immense volume of epigenetic and genetic ...

Birth control at the zoo Vets meet the elusive goal of hippo castration Common hippopotami (Hippopotamus amphibius) are vulnerable to extinction in the wild, but reproduce extremely well under captive breeding conditions. Females ...

Breaking down cancer's defense mechanisms A possible new method for treating pancreatic cancer which enables the body's immune system to attack and kill cancer cells has been developed by researchers. The method uses a drug which breaks down the ...

A gluttonous plant reveals how its cellular power plant devours foreign DNA Amborella trichopoda, a sprawling shrub that grows on just a single island in the remote South Pacific, is the only plant in its family and genus. It is also one of the oldest flowering ...

Charge order competes with superconductivity Today in Science express: Charge carriers in cuprate high-Tc superconductors form nanostripes that suppress superconductivity, as shown by guest researchers from Princeton ...

Elucidating biological cells' transport mechanisms A new study focuses on the motion of motor proteins in living cells, applying a physicist's tool called non-equilibrium statistical mechanics Motion fascinates physicists. It becomes even more intriguing when ...

How the cells remove copper We are fundamentally dependent on the presence of copper in the cells of the body. Copper is actually part of the body's energy conversion and protective mechanisms against oxygen radicals, as well as part of the immune system, and it also has great ...

New research provides insight into epilepsy Jørgen Kjems and Morten Trillingsgaard Venø, Department of Molecular Biology and Genetics and the Interdisciplinary Nanoscience Centre (iNANO), contribute to an article on microRNA-128 just published in Science. ...

EARTH Magazine: Navigating the risks of hazard research Alexandria, VA – When individuals die in a natural disaster or property damage is costly, can anyone be blamed? After the 2012 conviction of six Italian geoscientists on manslaughter charges related ...

Half of National Lottery in Spain sold at Christmas Sales of the National Lottery have fallen for the last five years, which shows that even the most traditional games have been affected by the economic crisis. In 2012, it collected 5.0163 billion euros, down 4.8% from 2011 ...

Neurobiology: The logistics of learning Learning requires constant reconfiguration of the connections between nerve cells. Two new studies now yield new insights into the molecular mechanisms that underlie the learning process. Learning and memory ...

Increasing personal savings, the 'Groundhog Day' way How a cyclical concept of time can boost your bank account Thinking about time as a cycle of recurring experiences — a reality Bill Murray's character knows all too well in the movie ...

Early detection of blinding eye disease could be as easy as scanning a barcode New hand-held optical device to catch early signs of retinal disease

New data for engineering immune cells shows early promise in solid tumors PHILADELPHIA — Engineered immune cells, called CARTmeso cells, designed to direct antitumor immune responses toward tumors that carry a protein called mesothelin, showed ...