CHICAGO – Positive results from four clinical trials of investigational targeted drugs for advanced ovarian, lung, and thyroid cancers, and chronic lymphocytic leukemia were highlighted today at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO). Findings from the mid- and late-stage trials suggest new ways to slow disease progression and improve survival for patients who experience relapses or resistance to available treatments. "Cancer relapses and treatment resistance have always been among the most daunting challenges in cancer care," said ...

VIDEO: Dr. Joyce Liu talks about her ovarian cancer research at ASCO 2014. Click here for more information. CHICAGO –– Significant improvement with the use of a combination drug therapy for recurrent ovarian cancer was reported at the annual meeting of the American Society of Clinical Oncology (ASCO) meeting in Chicago today. This is the first ovarian cancer study to use a combination of drugs that could be taken orally. The drugs were tested in a phase I combination study followed ...

VIDEO: Dr. Christopher Sweeney talks about his new study showing a drug combination extends survival by more than a year in metastatic prostate cancer. Click here for more information. CHICAGO – Men with newly diagnosed metastatic, hormone-sensitive prostate cancer lived more than a year longer when they received a chemotherapy drug as initial treatment instead of waiting to for the disease to become resistant to hormone-blockers, report scientists from Dana-Farber Cancer Institute ...

PORTLAND, Ore. – A drug used to treat men with late-stage prostate cancer proved effective in stemming progression of the disease in research participants who had not yet received chemotherapy and extended their survival, according to results from a multi-national Phase III clinical trial led by the Knight Cancer Institute at Oregon Health & Science University (OHSU). A comprehensive analysis of the study's results ― published in June 1 online edition of the New England Journal of Medicine and to be presented at the American Society of Clinical Oncology (ASCO) annual ...

LOS ANGELES (STRICTLY EMBARGOED UNTIL 7:30 A.M. EDT on JUNE 1, 2014 - ASCO Abstract No. 2005) – A multicenter team of investigators, led by researchers from the Cedars-Sinai Department of Neurosurgery, the Cedars-Sinai Maxine Dunitz Neurosurgical Institute and Dana-Farber Cancer Institute in Boston, have found in a Phase II clinical trial that an immune system-boosting therapy slowed the recurrence of glioblastoma multiforme, or GBM, the most common and deadly malignant brain tumor. They will present their findings in an oral presentation June 1 at the annual meeting ...

CHICAGO – Findings from four phase III clinical trials in breast, prostate, and colorectal cancers were released today at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO). The studies were presented in ASCO's Plenary session, which features the meeting's most important clinical cancer research with the greatest potential to impact patient care. These pivotal studies reveal new ways to optimize commonly used chemotherapy, hormone therapies, and newer targeted drugs, and answer critical questions about the comparative effectiveness of two common ...

University of Adelaide physics researchers have produced the world's most sensitive thermometer – three times more precise than the best thermometers in existence. Published in the journal Physical Review Letters, the researchers from the University's Institute for Photonics and Advanced Sensing (IPAS) report they have been able to measure temperature with a precision of 30 billionths of a degree. "We believe this is the best measurement ever made of temperature − at room temperature," says project leader Professor Andre Luiten, Chair of Experimental Physics in ...

VIDEO: Dr. Thomas and his team light an LED using energy stored in the outside coatings of an electrical cable. Click here for more information. Imagine being able to carry all the juice you needed to power your MP3 player, smartphone and electric car in the fabric of your jacket? Sounds like science fiction, but it may become a reality thanks to breakthrough technology developed at a University of Central Florida research lab. So far electrical cables are used only to transmit ...

Cold season may be just behind us, but a new discovery may shed light on how this common condition triggers asthma attacks. In a new research report published in the June 2014 issue of the Journal of Leukocyte Biology, researchers show that in individuals with asthma, statins significantly reduce the in vitro inflammatory response of human monocytes to rhinovirus (RV), the cause of the common cold. Not only does this discovery suggest that statins could help prevent or reduce the severity of asthma symptoms resulting from colds, but may also open the doors to further research ...

It appears that "The Pill" for men will have to wait a while longer. A new research report published in the June 2014 issue of The FASEB Journal involving mice, shows that a previously developed male hormonal oral contraceptive method (i.e. via testosterone) is unable to stop the production and / or the release of sperm. "Our research in mice explains why the efficacy of male hormonal contraception is not as effective as expected and it provides clues on how to improve the method," said Ilpo Huhtaniemi, M.D., Ph.D., M.D.hc, FMed.Sci., a researcher involved in the work ...

When it comes to reaping benefits of sprint interval training, it appears that men have won the battle of the sexes, if just barely. According to new research published in the June 2014 issue of The FASEB Journal, men create more new proteins as a result of this exercise than women do. The good news, however, is that men and women experienced similar increases in aerobic capacity. This study is the first to directly measure the creation of proteins made to adapt to this mode of exercise. The study also uniquely used methods that measure the cumulative making of proteins ...

Scientists at New York University and the University of Melbourne have developed a method using DNA origami to turn one-dimensional nano materials into two dimensions. Their breakthrough, published in the latest issue of the journal Nature Nanotechnology, offers the potential to enhance fiber optics and electronic devices by reducing their size and increasing their speed. "We can now take linear nano-materials and direct how they are organized in two dimensions, using a DNA origami platform to create any number of shapes," explains NYU Chemistry Professor Nadrian Seeman, ...

DARIEN, IL – A new study provides novel evidence suggesting that suicides are far more likely to occur between midnight and 4 a.m. than during the daytime or evening. Results show that the weighted, scaled mean suicide rate per hour was 10.27 percent after midnight, peaking at 16.27 percent between 2 a.m. and 2:59 a.m. In contrast, the mean suicide rate per hour was 2.13 percent between 6 a.m. and 11:59 p.m. When six-hour time blocks were examined, the observed frequency of suicide between midnight and 5:59 a.m. was 3.6 times higher than expected. "This appears to ...

A seven-year study of women who take antipsychotic medication while pregnant, proves it can affect babies. The observational study, published in the journal PLOS ONE, reveals that whilst most women gave birth to healthy babies, the use of mood stabilisers or higher doses of antipsychotics during pregnancy increased the need for special care after birth with 43 per cent of babies placed in a Special Care Nursery (SCN) or a Neonatal Intensive Care Unit (NICU), almost three times the national rate in Australia. As well as an increased likelihood of the need for intensive ...

DURHAM, N.C. -- Duke researchers have found a new type of neuron in the adult brain that is capable of telling stem cells to make more new neurons. Though the experiments are in their early stages, the finding opens the tantalizing possibility that the brain may be able to repair itself from within. Neuroscientists have suspected for some time that the brain has some capacity to direct the manufacturing of new neurons, but it was difficult to determine where these instructions are coming from, explains Chay Kuo, M.D. Ph.D., an assistant professor of cell biology, neurobiology ...

Sleeping well is a crucial factor contributing to our physical and mental restoration. SWS in particular has a positive impact for instance on memory and the functioning of the immune system. During periods of SWS, growth hormones are secreted, cell repair is promoted and the defence system is stimulated. If you feel sick or have had a hard working day, you often simply want to get some good, deep sleep. A wish that you can't influence through your own will – so the widely held preconception. Sleep researchers from the Universities of Zurich and Fribourg now prove ...

DARIEN, IL – A new study shows that college students who are poor sleepers are much more likely to earn worse grades and withdraw from a course than healthy sleeping peers. Results show that sleep timing and maintenance problems in college students are a strong predictor of academic problems even after controlling for other factors that contribute to academic success, such as clinical depression, feeling isolated, and diagnosis with a learning disability or chronic health issue. The study also found that sleep problems have about the same impact on grade point average ...

A team of international scientists led by Professor Jagadese J Vittal of the Department of Chemistry at the National University of Singapore's (NUS) Faculty of Science has successfully unraveled the chemical reaction responsible for propelling microscopic crystals to leap distances up to hundreds of times their own size when they are exposed to ultraviolet (UV) light. This popping effect, akin to the bursting of popcorn kernels at high temperatures, demonstrates the conversion of light into mechanical motion. It is the first instance of a "photosalient effect" driven ...

ANN ARBOR, Mich. — 1 in 2 hypertensive pregnant women who habitually snore may have unrecognized obstructive sleep apnea, a sleeping disorder that can reduce blood oxygen levels during the night and that has been linked to serious health conditions, new University of Michigan-led research shows. One in four hypertensive pregnant women who don't snore also unknowingly suffer from the sleeping disorder, according to the study that appears in the British Journal of Obstetrics and Gynecology. "We know that habitual snoring is linked with poor pregnancy outcomes for both ...

DARIEN, IL – A new study suggests that marijuana use is associated with impaired sleep quality. Results show that any history of cannabis use was associated with an increased likelihood of reporting difficulty falling asleep, struggling to maintain sleep, experiencing non-restorative sleep, and feeling daytime sleepiness. The strongest association was found in adults who started marijuana use before age 15; they were about twice as likely to have severe problems falling asleep (odds ratio = 2.28), experiencing non-restorative sleep (OR = 2.25) and feeling overly sleepy ...

TORONTO, June 2, 2014 — Even by three months of age, babies are visually able to locate objects that stand out from a group, a York University study has found. "For example, an infant can pick a red umbrella in a sea of grey ones," says Psychology Professor Scott Adler in the Faculty of Health, who led the research. "This indicates that babies at a very young age are able to selectively extract information from the environment, just like adults." Previously it was unknown how early this form of visual attention developed in infants. For the current study, both infants ...

LOS ANGELES – (June 2, 2014) – The rates of community-onset methicillin-resistant Staphylococcus aureus (CO-MRSA) varied dramatically among academic medical centers in California, New York, Illinois and North Carolina, suggesting there is not a uniform change in the "national epidemic" of the "superbug" that has generated extensive public health concern over the past decade, according to a new study. The study, published online ahead of print in the journal Clinical Infectious Diseases, surveyed hospital records of 4,171 cases of MRSA and MRSA-related infections between ...

LOS ANGELES (May 30, 2014) – An international team of scientists including researchers at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute and the University of Southern California found that an enzyme commonly used as a target for antidepressants may also promote prostate cancer growth. The study, published in the Journal of Clinical Investigation, found that suppressing the enzyme monoamine oxidase A, or MAOA, may reduce or even eliminate prostate tumor growth and metastasis in laboratory mice. The finding could open the door for physicians to use antidepressants ...

University of Tokyo researchers have described how a plant-virus protein suppresses an important plant defense mechanism that remembers viral genetic information, providing a new target for developing the first-ever chemical against plant viruses that globally cause more than $60 billion of crop losses each year. Invading viruses carry genetic material that hijacks the host cell's machinery, fooling it into producing proteins and new viruses. All cells from fungi to plants and mammals employ RNA silencing, a cellular process essential for the regulation of gene expression ...

LISBON, PORTUGAL (31 May 2014) – This week, the Population Council presented new research at the 13th Congress of the European Society of Contraception and Reproductive Health. Presentations included a pharmacokinetic analysis of the Council's investigational one-year contraceptive vaginal ring containing Nestorone® and ethinyl estradiol, and its investigational male contraceptive implant MENT®, as well as new approaches to "green contraception," including strategies to ensure that future contraceptive technologies are both effective and protect the environment. "The ...