Recycling is not only good for the environment, it's good for the brain. A study using rat cells indicates that quickly clearing out defective proteins in the brain may prevent loss of brain cells. Results of a study in Nature Chemical Biology suggest that the speed at which damaged proteins are cleared from neurons may affect cell survival and may explain why some cells are targeted for death in neurodegenerative disorders. The research was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health. One ...

Recent federal legislation imposes financial penalties on hospitals that experience excessive patient readmissions within 30 days. A new study published today in the Journal of Hospital Medicine looks at the potential of a program designed to improve the discharge process and prevent avoidable rehospitalizations. Developed by the Society of Hospital Medicine, Project BOOST (Better Outcomes by Optimizing Safe Transitions) Mentoring Program focuses on identifying patients at highest risk for readmissions, communicating discharge plans effectively, and ensuring close follow-up ...

Birthday celebrations often follow a formula, including off-key singing, making a birthday wish while blowing out candles, and the ceremonial cutting of the birthday cake. New research suggests that this ritual not only makes the experience more memorable, but might also improve the taste of the cake. The new collection of studies, published in Psychological Science, a journal of the Association for Psychological Science, reveals that the rituals we perform before eating -- even the seemingly insignificant ones -- can actually change our perception of the food we eat. Psychological ...

A new report issued today by the American College of Cardiology (ACC) and developed in collaboration with 10 other leading professional societies provides detailed criteria to help clinicians optimize the appropriate use of certain noninvasive vascular tests when caring for patients with known or suspected disorders of the venous (veins) system. Also included are first-time recommendations for when and how to use these tests to plan for or evaluate dialysis access placement. "Vascular lab testing is central to the care of patients with most peripheral vascular disorders, ...

MINNEAPOLIS/ST. PAUL (July 19, 2013) – Researchers at the University of Minnesota have identified infection-fighting and inflammation-suppressing functions for a gene associated with human autoimmune disease. The discovery, centered on a gene known as PTPN22, could set into motion new treatment approaches for autoimmune diseases like lupus, rheumatoid arthritis and type 1 diabetes. The key to these advances may lie with a better understanding of how a variant of PTPN22, known as a "risk variant," impacts autoimmune disease development and the behavior of myeloid cells ...

Nighttime heat waves are becoming more frequent in western Washington and Oregon. And if you don't sleep well in hot weather, this might be a good time to buy a fan, since records show that on average heat waves tend to strike around the last week of July. University of Washington research shows that the region west of the Cascades saw only three nighttime heat waves between 1901 and 1980, but that number quadrupled to 12 nighttime heat waves in the three decades after 1980, according to a paper published in the July issue of the Journal of Applied Meteorology and Climatology. ...

A gene related to neural tube defects in dogs has for the first time been identified by researchers at the University of California, Davis, and University of Iowa. The researchers also found evidence that the gene may be an important risk factor for human neural tube defects, which affect more than 300,000 babies born each year around the world, according to the U.S. Centers for Disease Control and Prevention. Neural tube defects, including anencephaly and spina bifida, are caused by the incomplete closure or development of the spine and skull. The new findings appear ...

Stem-cell researchers at UC San Francisco have found a key role for a protein called BMI1 that may help scientists direct the development of tissues to replace damaged organs in the human body. “Scientists have known that Bmi1 is a central control switch within the adult stem cells of many tissues, including the brain, blood, lung and mammary gland,” said Ophir Klein, MD, PhD, who directs the Craniofacial and Mesenchymal Biology (CMB) Program and serves as chair of the Division of Craniofacial Anomalies at UCSF. “Bmi1 also is a cancer-causing gene that becomes ...

TORONTO, July 19, 2013—The life-threatening MERS coronavirus that has emerged in the Middle East could spread faster and wider during two international mass gatherings involving millions of people in the next few months, according to researchers who describe the most likely pathways of international spread based upon worldwide patterns of air travel. Researchers led by Dr. Kamran Khan of St. Michael's Hospital encouraged health care providers to learn from the experience of SARS by anticipating rather than reacting to the introduction of MERS in travelers returning from ...

Most of the time, it takes decades of accumulating genetic errors for a tumor to develop. While this explains the general occurrence of cancer in adults, it leaves a gap in understanding of the cause of pediatric tumors. In a study published in the July issue of the Proceedings of the National Academy of Sciences, researchers found a missing piece of the pediatric cancer puzzle. Changxian Shen, PhD, senior research associate at the Center for Childhood Cancer and Blood Diseases at The Research Institute at Nationwide Children's Hospital, and Peter Houghton, PhD, director ...

The European Space Agency/NASA Solar and Heliospheric Observatory, or SOHO, captured this image of a gigantic coronal hole hovering over the sun's north pole on July 18, 2013, at 9:06 a.m. EDT. Coronal holes are dark, low density regions of the sun's outermost atmosphere, the corona. They contain little solar material, have lower temperatures, and therefore, appear much darker than their surroundings. Coronal holes are a typical feature on the sun, though they appear at different places and with more frequency at different times of the sun's activity cycle. The activity ...

UC San Francisco researchers have found a way to knock down cancers caused by a tumor-driving protein called “myc,” paving the way for patients with myc-driven cancers to enroll in clinical trials for experimental treatments. Myc acts somewhat like a master switch within cells to foster uncontrolled growth. Until now, it has been impossible to target with drugs. The discovery of an unexpected biochemical link within tumor cells should lead to clinical trials for experimental drug treatments that indirectly target myc and that already are being evaluated in human ...

Uruguay has it. So does Latvia, and Senegal. In fact, more than half of the world's countries have some degree of a guaranteed, specific right to public health and medical care for their citizens written into their national constitutions. The United States is one of 86 countries whose constitutions do not guarantee their citizens any kind of health protection. That's the finding of a new study from the UCLA Fielding School of Public Health that examined the level and scope of constitutional protection of specific rights to public health and medical care, as well as ...

In a bit of cosmic irony, planets orbiting cooler stars may be more likely to remain ice-free than planets around hotter stars. This is due to the interaction of a star's light with ice and snow on the planet's surface. Stars emit different types of light. Hotter stars emit high-energy visible and ultraviolet light, and cooler stars give off infrared and near-infrared light, which has a much lower energy. It seems logical that the warmth of terrestrial or rocky planets should depend on the amount of light they get from their stars, all other things being equal. But new ...

If you could hit the reset button on evolution and start over, would essentially the same species appear? Yes, according to a study of Caribbean lizards by researchers at the University of California, Davis, Harvard University and the University of Massachusetts. The work is published July 19 in the journal Science. The predictability of evolution over timescales of millions of years has long been debated by biologists, said Luke Mahler, a postdoctoral fellow at UC Davis and first author on the paper. For example, the late Stephen Jay Gould predicted that if you "rewound ...

Controversy exists over what some mental health experts call "hypersexuality," or sexual "addiction." Namely, is it a mental disorder at all, or something else? It failed to make the cut in the recently updated Diagnostic and Statistical Manual of Mental Disorders, or DSM-5, considered the bible for diagnosing mental disorders. Yet sex addiction has been blamed for ruining relationships, lives and careers. Now, for the first time, UCLA researchers have measured how the brain behaves in so-called hypersexual people who have problems regulating their viewing of sexual ...

One of the most crucial problems affecting the world today is the scarcity of potable water. In a bid to make clean water available at low cost, Mr Ramakrishna Mallampati, a PhD candidate at the National University of Singapore (NUS), experimented with water treatment techniques using materials that are easily available, and came up with novel ways to purify water using the peels of apples and tomatoes. This is the first time that the peels of the two fruits have been used to remove different types of pollutants in water. The studies were conducted under the guidance ...

A new study reports that subdiaphragmatic vagotomy reduces intake of sweet-tasting solutions in rats, and eliminate the hedonic perception produced by sucrose and saccharin in rats. Previous studies have shown that taste information and digestion information in animals during diet intake interact with each other in the central nervous system. So, how does subdiaphragmatic vagotomy influence the intake of sweet-tasting solution in rats? According to a study published in the Neural Regeneration Research (Vol. 8, No. 17, 2013), rats in the sham-surgery group drank more saccharin ...

Maternal alcohol consumption during pregnancy has detrimental effects on fetal central nervous system development. Maternal alcohol consumption prior to and during pregnancy significantly affects cognitive functions in offspring, which may be related to changes in cyclin-dependent kinase 5 because it is associated with modulation of synaptic plasticity and impaired learning and memory. Prof. Ruiling Zhang and team from Xinxiang Medical University explored the correlation between cyclin-dependent kinase 5 expression in the hippocampus and neurological impairments following ...

Recent studies have found that anesthesia drugs have neurotoxicity on the developing neurons, causing learning and memory disorders and behavioral abnormalities. Ketamine is commonly used in pediatric anesthesia. A clinical retrospective study found that children below 3 years old who receive a long time surgery, or because of surgery require ketamine repeatedly will exhibit the performance of school-age learning and memory disorders and behavioral abnormalities. Research group speculates that these abnormalities may be related to the potential neurotoxicity of ketamine. ...

EVANSTON, Ill. --- A new low-cost, high-resolution tool is primed to revolutionize how nanotechnology is produced from the desktop, according to a new study by Northwestern University researchers. Currently, most nanofabrication is done in multibillion-dollar centralized facilities called foundries. This is similar to printing documents in centralized printing shops. Consider, however, how the desktop printer revolutionized the transfer of information by allowing individuals to inexpensively print documents as needed. This paradigm shift is why there has been community-wide ...

The supply of dissolved iron to oceans around continental shelves has been found to be more variable by region than previously believed – with implications for future climate prediction. Iron is key to the removal of carbon dioxide from the Earth's atmosphere as it promotes the growth of microscopic marine plants (phytoplankton), which mop up the greenhouse gas and lock it away in the ocean. A new study, led by researchers based at the National Oceanography Centre Southampton, has found that the amount of dissolved iron released into the ocean from continental ...

An anti-cancer drug has been proven to be equally as effective in treating the most common cause of blindness in older adults as a more expensive drug specifically formulated for this purpose. The results of a two-year trial, led by Queen's scientist Professor Usha Chakravarthy, and published in The Lancet today (Friday 19 July), show that two drug treatments Lucentis and Avastin are equally effective in treating neovascular or wet age-related macular degeneration (wet AMD). Wet AMD is a common cause of sight loss in older people with at least 23,000 older people diagnosed ...

Babies have an innate biological need to be attached to caregivers, usually their parents. But what happens when babies spend a night or more per week away from a primary caregiver, as increasingly happens in cases where the parents share custody, but do not live together? In a new national study, University of Virginia researchers found that infants who spent at least one night per week away from their mothers had more insecure attachments to the mother compared to babies who had fewer overnights or saw their fathers only during the day. The finding is reported in the ...

Just over a century ago, Harvey Cushing published an account of a young woman who showed unusual symptoms because her glands were making excessive amounts of something. Subsequent research has shown that the thing in question is a set of hormones known as glucocorticoids that are produced by the adrenal glands, so "Cushing's disease" is now more commonly known as hyperadrenocorticism, at least by those who can pronounce it. The condition is particularly common in dogs, particularly as the animals grow older. Most cases result from a tumor in the pituitary gland but some ...