Though no systemic studies have been performed, it is generally believed that genes are the most sensitive toxicological endpoints for pollutants, and are thus desirable early warning indicators of environmental risks. A recent study, however, unexpectedly found that the sensitivity of the gene expression effect for cadmium was significantly lower than the individual level chronic toxicity indicators (such as the no observed effect concentration, NOEC). Therefore, the gene expression effect may not be the most sensitive toxicological endpoint. Dr Yan Zhenguang, Prof. Liu ...

PHILADELPHIA — The presence of multiple ovarian cancer genomes in an individual patient and the absence or downregulation of the gene LRP1B are associated with the development of chemoresistance in women with the high-grade serous cancer subtype of ovarian cancer whose disease recurs after primary treatment. These study results are published in Cancer Research, a journal of the American Association for Cancer Research. David Bowtell, Ph.D., head of the Cancer Genomics and Genetic Program at the Peter MacCallum Cancer Centre in Melbourne, Australia, and colleagues generated ...

Children who spend more than three-quarters of their time engaging in sedentary behaviour, such as watching TV and sitting at computers, have up to nine times poorer motor coordination than their more active peers, reveals a study published in the American Journal of Human Biology. The study, involving Portuguese children, found that physical activity alone was not enough to overcome the negative effect of sedentary behaviour on basic motor coordination skills such as walking, throwing or catching, which are considered the building blocks of more complex movements. "Childhood ...

Chevy Chase, MD—A study to be published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM) suggests that physical activity for premenopausal women is very effective in reducing sclerostin—a known inhibitor of bone formation. In addition, physical training enhances IGF-1levels, which have a very positive effect on bone formation. Bone is a tissue that is always changing due to hormonal changes and physical activity, or lack thereof. Sclerostin is a glycoprotein produced almost exclusively by osteocytes, the most abundant cells found ...

Chevy Chase, MD—A study to be published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM) shows consumption of a Mediterranean diet enriched with olive oil for two years is associated with increased serum osteocalcin concentrations, suggesting a protective effect on bone. Age-related bone mass loss and decreased bone strength affects women and men alike are an important determinant of osteoporosis and fracture risk. Studies have shown that the incidence of osteoporosis in Europe is lower in the Mediterranean basin. The traditional Mediterranean ...

Researchers at Moffitt Cancer Center have found that when breast cancer patients are offered pre-test genetic counseling before definitive breast cancer surgery, patients exhibited decreases in distress. Those offered pre-test genetic counseling after surgery improved their informed decision-making. Patients in both groups showed increases in their cancer knowledge with pre-test genetic counseling. The study, funded by the American Cancer Society, appeared in a recent issue of the Annals of Surgical Oncology. Given the role of breast cancer gene status in treatment ...

Men with prostate cancer in Texas may be driving more than three times farther than needed to obtain radiation oncology treatments for their cancer when treated at a urology-owned radiation oncology practice versus other facilities, according to a study to be published online August 15, 2012, and in the September 1, 2012, print issue of the International Journal of Radiation Oncology*Biology*Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology (ASTRO). This study reviewed 229 urology practices in Texas and found that 5 ...

You are invited to a 365 Love Experience book signing event at the Smyrna Community Center. The author, Torion Kent will take you on an inspirational journey inside the book, Love Always. Love Daily. 365 Love - Daily Notes Music and Quotes to Promote Personal Growth in Love, through creative expressions of dance, drama, poetry, song and more. This live, entertaining book signing event will take place on Sunday, October 7, 2012 from 3 PM - 6 PM EST at the Smyrna Community Center, 200 Village Green Circle, Smyrna, GA 30080. The event is free and open to the public. All guests ...

Ringing, whistling and pulsing in the ears is a validated and very real health concern, known as tinnitus. The condition is mistakenly confused with hearing loss, when in reality it is often a side effect of other ailments such as high blood pressure, inner ear damage or age related illness. TreatingTinnitusRinging.com provides a comprehensive and detailed study of the many aspects of the condition, including the recommendation of a remedy that has assisted over a million people who suffer from this ailment. For millions of people who lay awake at night, unable to fall ...

Cosmetology students at at ITS Academy of Beauty, 200 Southwest C Ave. in Lawton are helping students ages 4-18 return to school in style with a variety of back to school specials. The specials include: buy one get one free haircuts; $2 off any regularly priced haircut; $4 off acrylic nail services and 15% off all Peter Hantz retail products. "By offering deep discounts to our already reasonably-priced services, we can help ensure more students can go back to school in style," said Jessica Wolman, one of the owners of the award-winning cosmetology schools. ...

Family-owned Westshore Beach Inn Bistro in the sunny Hawke's Bay was awarded a prestigious 2012 TripAdvisor Excellence Award earlier this month. TripAdvisor Excellence Awards are given out annually to businesses from around the world that have exceeded customers' expectations and achieved exceptional ratings through the popular customer-rated site. The Napier bistro is part of the Econo Lodge Westshore Beach & Inn and takes out the top spot with an almost perfect score, rating 1 from the 91 Napier restaurants on TripAdvisor. The kitchen is run by chefs David ...

On Monday, August 6th, following their annual convention, NAAFA convened its second NAAFA HAES Summit with the theme of Equality At Every Size using HAES. Over forty individuals from various health related fields were in attendance. These included physicians, psychologists, nutritionists, researchers and health advocates representing several organizations, non-profits and academic institutions, including attendees from Japan and Canada. The Summit's keynote speaker psychologist, Dr. Debora Burgard, PhD, FAED, HAES pioneer, writer, activist and NAAFA Advisory Board member, ...

Here are some of the differences between LeavesOut gutter guards and gutter cleaning: Gutter Cleaning: 1. The Wear and Tear- Your roof and gutters are torn, scratched, dented and broken every time someone cleans out your gutters. 2. Are they really clog free?- How do you know if all the gutters and downspouts are really clean and free flowing outside of climbing up the ladder yourself and inspecting. 3. What happens every time they overflow?- It causes problems to your landscaping, foundation, basement, windows, doors, siding, concrete, and anything else including ...

Accessory Power is proud to introduce the new Restore 9200 to its ReVIVE line of solar battery packs, adapters and chargers. The ReVIVE ReStore 9200 incorporates a high-efficiency, multi-functional battery pack and LED flashlight. Fully charge the ReStore 9200 within 10 hours via USB-charging port. Once fully charged the 9200 will have the battery capacity to fully charge an iPad or other tablet several times over. Additionally, the ReStore 9200 can be charged through direct sunlight by use of the compatible ReStore XL add-on solar panel. "By allowing you freedom ...

August 15th would have marked the late Julia Child's 100th birthday and in celebration of the legendary chef, the Anaheim White House will serve a special 3-course prix-fixe menu with recipes from her groundbreaking cookbook, "Mastering the Art of French Cooking." The menu was assembled by owner Bruno Serato and will be prepared by Executive Chef Eddie Mezza from Wednesday, August 15 through Tuesday, August 21 for $50 per person. The first course will feature a Split Pea Soup made with ham, onions and carrots. Main course options include Beef Bourguignon prepared ...

In an age of instant gratification, more timely recognition for a task well done is ever more important. That's why TharpeRobbins, a global leader in the managed employee recognition and rewards industry, has launched The Power of You, a unique reward and recognition program, which offers recognition following the accomplishment rather than waiting for the end of the year banquet. A new, on-the-spot, e-cards program launches this month, enabling employees to nominate a co-worker or a manager for a special e-card typically delivered within 24 hours. "The big ...

Eidogen-Sertanty, Inc., a San Diego-based computational drug discovery solutions provider, announced today that it will release an Android version of MObile REagents (MORE). Mobile Reagents provides free access to over 16 million commercial available chemicals offered by over 50 vendors, including real-time availability for some vendors. Mobile Reagents has been in routine use by thousands of users worldwide running on Apple devices supporting iOS. With MORE, you can search for available chemicals by name, formula or by drawing chemical structures with your fingertips. ...

Over the years, many recording artists have been known to drop no less than one CD per calendar year. However, the talented singer, songwriter, composer and producer Gina Carey is quite the exception to the rule. If releasing two CD's in one consecutive year wasn't enough, Gico Music recording artist Gina Carey plans to drop a third soulful masterpiece on Tuesday, September 4, 2012 ending with three CD's in one year. On February 14, 2012, "Valentines Day," Gina graced her fans with "Love Letters," a beautiful collection of well written and performed ...

Chelsea Sinking is fast becoming the Alternative band to know! Having just released their debut EP last month, the internet is a buzz with talk about this richly talented Florida based band. The well established music blog, Kings of A&R have already taken note. The blog singled out the band's official music video for their hit-in-the-making "Stand." Kings of A&R describe the vocals as "explosive" and says Chelsea Sinking's original sound is reminiscent of Switchfoot, Third Eye Blind, Coldplay, Kings of Leon and Relient K. Chelsea Sinking's ...

Everyone can imagine that the life of a surgical resident is challenging and tiring. For the first time, lives are in their hands, and they are encountering all kinds of new situations. A recent study has found that surgical residents are in fact very tired, and their fatigue may increase their risk of making medical errors -- possibly putting patients' health or lives in danger. "Drunk" Doctors The study, lead by Dr. Frank McCormick of the Harvard Combined Orthopaedic Residency Program and reported in the Archives of Surgery, revealed that residents averaged ...

Cisco, GDT, and Golden Living have released a video case study that outlines the business benefits of Golden Living's Cisco powered collaboration solution. Designed and implemented by General DataTech L.P. (GDT), Golden Living's solution supports more than forty-three thousand employees in forty states. The company implemented the solution as part of their overall efforts to provide the best possible care for the more than sixty thousand patients that they treat on a daily basis. Collaboration technology has enabled their clinicians, administrators, partners, and patients ...

Web designers and other entrepreneurs now have the opportunity to increase their profit margins with the economical reseller hosting packages offered by PlotHost. Such hosting plans let web developers, designers and other entrepreneurs act as a hosting company by selling web space that they lease from the hosting provider. "For a while our main focus had been on improving the quality of our shared hosting packages", reports Cameron Slater the COO of PlotHost. He goes on to say, "For over a year we have been receiving requests for reseller plans until we ...

Fuel prices make it difficult to take a trip to Italy or visit "Little Italy" in New York or Boston? Not to worry. The Jeffersonville Italian Festival 2012 will give you the feeling of being at an authentic Italian neighborhood street festival in "Little Italy" without leaving southern Indiana. Featuring authentic Italian food, music, and activities in a family-friendly atmosphere, the Jeffersonville Italian Festival 2012 will allow everyone to be "Italian for a day." This year, Adrienne and Co. Bakery Cafe is teaming up with the J. B. ...

ePanic Button is presenting a free webinar, "Domestic Violence, Sexual Assault and Employment: Rights and Responsibilities," on September 5, 2012 from 2:00-3:00 p.m. EST. The guest speaker is Julia Parish of the Legal Aid Society-Employment Law Center. Attendees can register here: http://epanicbutton.com/free-webinar-domestic-violence-sexual-assault-and-employment-rights-and-responsibilities/ Domestic violence and sexual assault impact more than just life at home - the effects are often felt in the workplace, both directly and indirectly. Ms. Parish will ...

Every 68 seconds another American develops Alzheimer's disease. Education and training in dementia care for heath care staff has been identified as a priority by the Centers for Medicare & Medicaid Services (CMS). The National Plan to Address Alzheimer's Disease (NPAAD) developed by the U.S. Department of Health and Human Services (HHS) has set as a goal enhanced care quality and efficiency for the Alzheimer's and dementia population. High-quality care should be provided from the point of diagnosis onward in settings including doctor's offices, hospitals, people's homes ...