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Scientists uncover a multibillion-year epic written into the chemistry of life
Science

Scientists uncover a multibillion-year epic written into the chemistry of life

The origin of life on Earth has long been a mystery that has eluded scientists. A key question is how much of the history of life on Earth is lost to time. It is quite common for a single species to "phase out" using a biochemical reaction, and if this happens across enough species, such reactions could effectively be "forgotten" by life on Earth. But if the history of biochemistry is rife with forgotten reactions, would there be any way to tell? This question inspired researchers from the Earth-Life Science Institute (ELSI) at the Tokyo Institute of Technology, and the California Institute of Technology (CalTech) ...

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1 in 8 pregnant people have a disability, but significant gaps exist in the provision of accessible care

Toronto, ON, May 28, 2024 – People with disabilities account for 13% of all pregnancies in Ontario, but a new report shows that this population was more likely to experience pregnancy complications such as emergency department visits, hospitalizations, and preterm birth. Researchers from ICES, the University of Toronto Scarborough, and the Centre for Addiction and Mental Health (CAMH) have released a landmark report detailing findings from one of the largest studies to date on disability and pregnancy. Funded by the US National Institutes of Health, the Disability and Pregnancy Study used healthcare ...

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Statins associated with decreased risk for CVD and death, even in very old adults

Embargoed for release until 5:00 p.m. ET on Monday 27 May 2024 Annals of Internal Medicine Tip Sheet @Annalsofim Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent. ---------------------------- 1. Statins associated with ...

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Secrets of sargassum: Scientists advance knowledge of seaweed causing chaos in the Caribbean and West Africa
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Secrets of sargassum: Scientists advance knowledge of seaweed causing chaos in the Caribbean and West Africa

Researchers have been working to track and study floating sargassum, a prolific seaweed swamping Caribbean and West African shorelines, and causing environmental and economic harm. The stranded seaweed blocks fishing boats; threatens tourism; disrupts turtle nesting sites, reefs and mangroves, and releases toxic gas, which impacts human health and damages electrical equipment. First reported by Christopher Columbus in the 15th century, floating mats of sargassum have long been present in the North Atlantic. However, since 2011, a floating population has established ...

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Bioinformatics approach could help optimize soldiers’ training for improved readiness and recovery
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Bioinformatics approach could help optimize soldiers’ training for improved readiness and recovery

Of the many perils facing members of the military, injuries incurred in training or on deployment repeatedly sideline elite operators. “It’s a pervasive problem,” says Dhruv Seshadri, an assistant professor of bioengineering in Lehigh University’s P.C. Rossin College of Engineering and Applied Science. “We’re looking at how we can integrate physiological data, biomechanical data, and subjective assessments to help reduce the risk of these injuries happening in the first place, and when they do happen, how we can use those data to accelerate the soldier’s return to operation.” Seshadri ...

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Feeding infants peanut products protects against allergy into adolescence

Feeding children peanuts regularly from infancy to age five reduced the rate of peanut allergy in adolescence by 71%, even after many years when the children ate or avoided peanut as desired. The new findings provide conclusive evidence that introducing peanuts into babies’ diets early will achieve long-term prevention of peanut allergy. Lead investigator Professor Gideon Lack from King’s College London said: “Decades of advice to avoid peanuts has made parents fearful of introducing peanuts at an early age. The evidence is clear that early introduction of peanut in infancy ...

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Investigating the origin of circatidal rhythms in freshwater snails
Science

Investigating the origin of circatidal rhythms in freshwater snails

Organisms, including humans, follow a schedule that coordinates important bodily functions such as sleep-wake cycles, metabolism, hormone production, cognitive function, and feeding habits to environmental cycles. While most organisms possess circadian rhythms synchronized with the 24-hour day-night cycle, they have also developed other internal clocks to suit their local environments. Marine animals have evolved circatidal rhythms, aligning activities with the 12.4-hour tidal cycle, complementing circadian rhythms. Researchers from Chiba University have discovered that snails living in downstream tidal areas have biological ...

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Surprising properties of elastic turbulence discovered
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Surprising properties of elastic turbulence discovered

Blood, lymph fluid and other biological liquids can have surprising and sometimes troubling properties. Many of these biological solutions are non-Newtonian fluids, a type of liquid that is characterized by a non-linear relationship between stress and strain. Consequently, non-Newtonian fluids don’t necessarily behave as one would expect from a liquid. For example, some of these peculiar fluids deform when touched lightly but will act almost as a solid when a strong force is applied. And biological ...

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Charge your laptop in a minute? Supercapacitors can help; new research offers clues

Imagine if your dead laptop or phone could charge in a minute or if an electric car could be fully powered in 10 minutes. While not possible yet, new research by a team of CU Boulder scientists could potentially lead to such advances. Published today in the Proceedings of the National Academy of Sciences, researchers in Ankur Gupta’s lab discovered how tiny charged particles, called ions, move within a complex network of minuscule pores. The breakthrough could lead to the development of more efficient energy storage devices, such as supercapacitors, said Gupta, an assistant professor of chemical and biological engineering. “Given the critical role ...

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On repeat: Biologists observe recurring evolutionary changes, over time, in stick insects
Science

On repeat: Biologists observe recurring evolutionary changes, over time, in stick insects

LOGAN, UTAH, USA – A long-standing debate among evolutionary scientists goes something like this: Does evolution happen in a predictable pattern or does it depend on chance events and contingency? That is, if you could turn back the clock, as celebrated scientist Stephen Jay Gould (1941-2002) described in his famous metaphor, “Replaying the Tape of Life,” would life on Earth evolve, once again, as something similar to what we know now, or would it look very, very different? “If you frame it as an either/or question, it’s too simplistic,” says Utah State University evolutionary biologist Zachariah Gompert. “The answer isn’t ‘completely ...

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Study finds discreet shipping used to sell e-cigarettes to minors
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Study finds discreet shipping used to sell e-cigarettes to minors

Researchers at the U of A found self-identified small business owners on TikTok are circumventing a number of local, state and federal laws that restrict the individual sale of tobacco products. Specifically, the researchers found that 45% of the videos highlighted the fact that they did not require identification to verify the purchaser’s age. “Many states have laws that govern procedures necessary to sell e-cigarettes,” explained lead researcher Page Dobbs, an associate professor of public health in the Department of Health, Human Performance and Recreation ...

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African scientists call for equitable research partnerships to advance microbiome research

Leading African scientists have issued a compelling call for more equitable research partnerships in a new paper published in Nature Medicine. The paper underscores the critical need for fair and collaborative research efforts to explore the unique and diverse microbiomes found in African populations and environments. Historically, these microbiomes have been underrepresented in global studies. Over the past two decades, our understanding of the role played by the microbiome in different ecosystems has significantly expanded. For ...

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Virginia Tech entomologist sheds light on 250-year-old mystery of the German cockroach
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Virginia Tech entomologist sheds light on 250-year-old mystery of the German cockroach

May 24, 2024 -- A team of international scientists, including Virginia Tech entomologist Warren Booth, have solved the 250-year-old origin puzzle of the most prevalent indoor urban pest insect on the planet: the German cockroach. The team's research findings, representing the genomic analyses of over 280 specimens from 17 countries and six continents, show that this species evolved some 2,100 years ago from an outside species in Asia and were released this week in the Proceedings of the National Academy of Sciences journal. One ...

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Advancing skin science: explore Skin Ageing & Challenges 2024 Strategic Topics in Malta this November
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Advancing skin science: explore Skin Ageing & Challenges 2024 Strategic Topics in Malta this November

Get introduced to the latest advances in skin research at the 15th International Conference on Skin Ageing & Challenges 2024 on November 5-6 at Corinthia Palace in Malta. Skin Ageing & Challenges 2024 will cover the hottest topics shaping the future of skin aging and rejuvenation. How will Skin Ageing & Challenges 2024 Expand Your Knowledge? Senolytics: Exploring new ways to fight cell aging with innovative senolytic treatments. Extracellular Vesicles: Discovering the potential of EVs for skin regeneration and repair. Skin Microbiota / Mitochondria Transplantation: Introducing approaches to harness the power of microbiome and mitochondrial transplantation ...

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MSK Research Highlights, May 24, 2024
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MSK Research Highlights, May 24, 2024

New research from Memorial Sloan Kettering Cancer Center (MSK) investigates a promising approach against diabetic retinopathy and finds patients with early-onset colorectal cancer likely don’t need more frequent surveillance colonoscopies. Anti-ceramide immunotherapy promising against diabetic retinopathy, animal studies suggest Diabetic retinopathy is a condition that affects blood vessels in people with diabetes and can cause blindness. Now a new study from a team at MSK, Michigan State University, and the University of Oklahoma Health Sciences Center shows that diabetic retinopathy can be considered a “ceramidopathy” — which ...

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Preterm and early-term delivery after heat waves in 50 US metropolitan areas

About The Study: Preterm and early-term birth rates increased after heat waves, particularly among socioeconomically disadvantaged subgroups in this cohort study. Extreme heat events have implications for perinatal health. Corresponding Author: To contact the corresponding author, Lyndsey A. Darrow, Ph.D., email ldarrow@unr.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.12055) Editor’s Note: Please see the article for additional information, including other authors, author contributions and ...

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Autophagy in pancreatitis
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Autophagy in pancreatitis

Researchers are exploring a new potential avenue for pancreatitis treatment: autophagy, a cellular recycling process. Autophagy helps maintain healthy pancreatic acinar cells by removing damaged organelles like mitochondria and the endoplasmic reticulum (ER). A new review published in eGastroenterology highlights the link between defective autophagy and pancreatitis. Impaired autophagy contributes to pancreatitis by allowing damaged organelles to accumulate within acinar cells. This accumulation disrupts cellular function and can ultimately lead to cell death. "Autophagy plays a vital role in keeping pancreatic acinar cells healthy," ...

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Unveiling a novel AAK1 inhibitor: How chemical proteomics unlocked therapeutic potential
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Unveiling a novel AAK1 inhibitor: How chemical proteomics unlocked therapeutic potential

Enhancing drug development for life-threatening diseases like cancer hinges on a deep understanding of protein kinases, making it a focal point for researchers. These enzymes, encoded by more than 500 human genes, serve as critical players in cellular signaling pathways. However, if these signals are dysregulated, they can disrupt the normal cellular mechanisms, leading to diseases such as cancer. Protein kinase inhibitors have therefore provided a promising avenue in therapeutic intervention to disrupt the aberrant signaling ...

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Announcement of winners for the third “Marie Sklodowska Curie Award”
Science

Announcement of winners for the third “Marie Sklodowska Curie Award”

JST has selected winners for the third Marie Sklodowska Curie Award for young female researchers. For the third Marie Sklodowska Curie Award, we accepted applications from October 2 to December 11, 2023. Through document screenings and interviews with external experts, we have selected one Grand Prize winner and two Inspiration Prize winners. JEOL Ltd. will award 1M yen for the Grand Prize and 500K yen for each Inspiration Prize. JST recognizes the importance of initiatives designed to promote the activities of female researchers in science, technology, and innovation, and based on this belief we established the “Marie ...

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Baby bonuses and wedding bells: how life's big moments can challenge startups

Life-changing events like the birth of a child, the purchase of a new home, or a lottery win could threaten the survival of a new business venture, research from Edith Cowan University (ECU) has found. A recent study led by ECU’s Professor of Entrepreneurship and Innovation Pi-Shen Seet with Associate Professor Wee-Liang Tan from the Singapore Management University found that positive family events had a comparatively greater influence, albeit negatively, on the survival of a new venture, compared with negative events. “A positive family event, like the birth of a child, often has an emotional spin-on effect for an entrepreneur ...

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Wagner named 2024 recipient of the ASME George Westinghouse Gold Medal
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Wagner named 2024 recipient of the ASME George Westinghouse Gold Medal

Robert Wagner, associate laboratory director for the Energy Science and Technology Directorate at the Department of Energy’s Oak Ridge National Laboratory, has been selected to receive the George Westinghouse Gold Medal from the American Society of Mechanical Engineers, or ASME. The award recognizes his work to advance state-of-the-art clean power generation systems through research on combustion, fuel technologies and controls. Wagner will be presented the award in October during ASME’s ...

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Celebrating 25 Inspiring Women in Plant Biology
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Celebrating 25 Inspiring Women in Plant Biology

The American Society of Plant Biologists (ASPB) Women in Plant Biology Committee recently named 25 Inspiring Women in Plant Biology to celebrate their achievements and inspire future generations of female plant biologists. This committee, dedicated to addressing particular concerns to women scientists and promoting the inclusion of female plant biologists throughout the Society and profession, created this list with input and nominations from the community. “This initiative was inspired by two things: First, our desire to improve recognition of inspiring women scientists. We have had ...

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SWOG researchers will present key results at ASCO 2024

Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), will share results of their work in 30 presentations at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, which takes place May 31 – June 4 in Chicago. The clinical trials reported on in this work are led by SWOG and conducted by the NIH-funded NCI National Clinical Trials Network (NCTN) and the NCI Community Oncology Research ...

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Science

MD Anderson Research Highlights: ASCO 2024 Special Edition

ABSTRACTS: 2018, 2517, 3513, 5504, 6016, 7007, 9515, 12017, LBA8007, LBA9516 CHICAGO ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. This special edition features presentations by MD Anderson researchers at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting. In addition to the ...

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Does it matter if your kids listen to you? When adolescents reject mom’s advice, it still helps them cope

URBANA, Ill. – Parents are often eager to give their adolescent children advice about school problems, but they may find that youth are less than receptive to their words of wisdom. However, kids who don’t seem to listen to their parents may still benefit from their input, a new study from the University of Illinois Urbana-Champaign shows. The researchers looked at conversations between fifth-grade students and their mothers about academic problems, identifying mom’s advice strategies and the youth’s response. Then they correlated these findings with how ...

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