A more accurate way to scan for tuberculosis (TB) has been developed by UK and US researchers, using positron emission tomography (PET). The team, from the Rosalind Franklin Institute, the Universities of Oxford and Pittsburgh and the National Institutes of Health in the USA, have developed a new radiotracer, which is taken up by live TB bacteria in the body. Radiotracers are radioactive compounds which give off radiation that can be detected by scanners and turned into a 3D image. The new radiotracer, called FDT, enables PET scans to be used for the first time ...

Ammonites were not in decline before their extinction, scientists have found. The marine molluscs with coiled shells and one of palaeontology’s great icons flourished in Earth’s oceans for more than 350 million years until they died out during the same chance event that wiped out the dinosaurs 66 million years ago. Some palaeontologists have argued that their demise was inevitable and that ammonite diversity was decreasing long before they went extinct at the end of the Cretaceous. However new research, published today in Nature Communications and led by palaeontologists at the ...

Being nursed by a single parent could be an evolutionary strategy to curb the spread of harmful microbes in mammals, according to a novel theory developed by mathematicians. The rainforests of Malaysia are home to the only known case of a wild male mammal that produces milk. The Dayak fruit bat is a vanishingly rare case of male milk production, despite the fact that the potential for breastfeeding remains in place in most male mammals.  In the 1970s, evolutionary theorists posited that the near absence of ...

Los Angeles, CA (June 27, 2024) —A new study published in the journal Nature Communications led by paleontologists at the University of Bristol along with a team of international researchers, including Dr. Austin Hendy, Curator of Invertebrate Paleontology at the Natural History Museum of Los Angeles County, finds that instead of fizzling out ahead of their extinction, ammonoids were still going strong across the globe in the Late Cretaceous. Made possible by museum collections, the new study compared their diversity across the globe just prior to extinction, unearthing the complex evolutionary history ...

Embargoed until 4am EDT Cleveland, OH (Thursday, June 27, 2024) – Cleveland Clinic and app developer FitNow, Inc.  have launched the Cleveland Clinic Diet app, which offers health and diet advice built upon evidence-based nutrition science and clinical success, paired with a comprehensive food and fitness tracker.     The app provides individualized guided support with the input of Cleveland Clinic health experts to help users make sustainable changes to their lifestyle and dietary habits for better health and well-being.     “We know that health is about far more than just weight. ...

Researchers from Tampere University, Finland, and the University of Pittsburgh, USA, have developed a tiny robot replicating the aerial dance of falling maple seeds. In the future, this robot could be used for real-time environmental monitoring or delivery of small samples even in inaccessible terrain such as deserts, mountains or cliffs, or the open sea. This technology could be a game changer for fields such as search-and-rescue, endangered species studies, or infrastructure monitoring. At Tampere University, Professor Hao Zeng and Doctoral Researcher Jianfeng Yang ...

Bottom Line: Patients with treatment-refractory cancers who received eligibility and testing waivers to participate in a large basket/umbrella oncology trial had similar rates of clinical benefit and adverse events as patients who participated in the trial without waivers. Journal in Which the Study was Published: Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR) Author: Hans Gelderblom, MD, senior author of the study and chair of the Department of Medical Oncology at the Leiden University Medical Center in the Netherlands Background: Eligibility requirements ...

Psilocybin mushrooms are the psychedelic substance most often used in the U.S., with its popularity outpacing other psychedelic drugs such as MDMA (known as ecstasy), according to a new RAND report.   Based on a new national survey, researchers found that about 12% of respondents reported using psilocybin at some point over their lives and 3.1% reported using the substance over the past year. An estimated 8 million American adults used psilocybin in 2023.   Psychedelic substances such as psilocybin mushrooms and MDMA long have been touted as holding promise for treating various mental ...

Arlington, Va. — June 27, 2024 — A new study published today in the American Journal of Infection Control (AJIC) describes the outcome of a new approach to testing for Clostridioides difficile (C. diff) guided by the principles of diagnostic stewardship. At Memorial Healthcare System in Hollywood, Fla., revised rules for when C. diff tests could be ordered helped to reduce inappropriate testing by 20%, which in turn can help rein in the overtreatment of patients. C. diff is a common and potentially dangerous gastrointestinal pathogen, often linked to healthcare-associated infections ...

Like the flutter of a butterfly's wings, sometimes small and minute changes can lead to big and unexpected results and changes in our lives. Recently, a team of researchers at Pohang University of Science and Technology (POSTECH) made a very small change to develop a material called “spin-orbit torque (SOT),” which is a hot topic in next-generation DRAM memory.   This research team, led by Professor Daesu Lee and Yongjoo Jo, a PhD candidate, from the Department of Physics and Professor Si-Young ...

Machines have evolved to meet the demands of daily life and industrial use, with molecular-scale devices often exhibiting improved functionalities and mechanical movements. However, mastering the control of mechanics within solid-state molecular structures remains a significant challenge. Researchers at Ulsan National Institute of Science and Technology (UNIST), South Korea have made a groundbreaking discovery that could pave the way for revolutionary advancements in data storage and beyond. Led by Professor Wonyoung Choe in the Department of Chemistry at UNIST), a team of scientists has developed zeolitic imidazolate frameworks (ZIFs) that mimic intricate machines. These molecular-scale ...

Despite high hopes, a drug that wipes out the namesake cell type associated with the disease eosinophilic esophagitis (EoE) doesn’t make patients feel better and doesn’t reverse tissue damage in their throats. Meanwhile, data show that a different drug that had previously been approved for use in adults and teens with EoE is also safe and effective for children under 12 who weigh at least 15 kg (about 33 pounds). The results of these clinical trials—plus an accompanying editorial—appear in the June 17, 2024, edition of The New England Journal of Medicine. “Together, these ...

For a billion years, single-celled eukaryotes ruled the planet. Then around 700 million years ago during Snowball Earth — a geologic era when glaciers may have stretched as far as the Equator — a new creature burst into existence: the multicellular organism. Why did multicellularity arise? Solving that mystery may help pinpoint life on other planets and explain the vast diversity and complexity seen on Earth today, from sea sponges to redwoods to human society. Common wisdom holds that oxygen levels had to hit a certain threshold ...

NORMAN, OKLA. – Bin Wang, a professor in the School of Sustainable Chemical, Biological and Materials Engineering at the University of Oklahoma, has received a Friedrich Wilhelm Bessel Research Award from the Alexander von Humboldt Foundation. Wang was selected for his contributions to computational catalysis and physical chemistry. The Bessel Award is funded by the German Federal Ministry of Education and Research to foster collaborative relationships between international academics and German researchers. The award ...

Rates of coronary heart disease in the UK have declined by about 30% over the past two decades, but this has been offset by rising rates of other conditions affecting the heart or blood vessels, finds a study in The BMJ today. What’s more, improvements in rates of coronary heart disease almost exclusively appeared to benefit the over 60s, with little or no improvement in younger or more deprived groups, the results show. As such, the researchers say future prevention strategies might need to consider a broader spectrum ...

One in six integrated care boards (ICBs) in England have stopped accepting new patients for specialist weight management services as their referral numbers spiral out of control, an investigation by The BMJ has found. ICBs are responsible for planning health services for their local population. At least seven out of 42 ICBs across the country - covering Manchester, Bristol, Suffolk, Leicester, Essex, and much of Yorkshire - have had to close a specialist (tier 3) weight management service list in their area, with many warning that demand is far exceeding capacity, reports Elisabeth Mahase. Experts have said the rise in obesity and the demand for weight-loss injections may be fuelling ...

Dementia risk factors associated with cardiovascular health may have increased over time compared to factors such as smoking and having less education, finds a new study led by UCL researchers. The study, published in The Lancet Public Health, explored how the prevalence of dementia risk factors had changed over time and how this could impact rates of dementia in the future. It is estimated that there are currently 944,000 people living with dementia in the UK and 52% of the UK public – 34.5 million ...

June 26, 2024 (Toronto, Canada) – A new study conducted by the Centre for Addiction and Mental Health (CAMH), Bordeaux University Hospital, France, and the World Health Organization (WHO) has found that individuals with alcohol dependence who undergo rehabilitation or maintain abstinence experience significantly lower risks of developing alcohol-associated cancers. The article, entitled Alcohol rehabilitation and cancer risk: a nationwide hospital cohort study in France was published today in Lancet Public Health. It is the largest of its kind to provide evidence linking reduced ...

University of Leeds news Children who are not considered “school ready” by their teachers are more than twice as likely to become persistently absent at some point in their education, according to a new study led by the University of Leeds. Researchers analysed data for 62,598 children aged 5-13 from across the Bradford district and compared it with school absence records between the academic years 2012/2013 and 2019/2020 to identify associations between early childhood problems and absenteeism. The team from the School of Psychology and the Born in Bradford Centre for Applied Education Research found ...

A new narrative review1 led by researchers at UCL and Birmingham Children’s Hospital has found there is a lack of evidence to demonstrate the effective use of continuous glucose monitors (CGMs) in people not living with diabetes (PNLD).   In the study, published in Diabetic Medicine, researchers conclude there is currently little published evidence on how accurate CGMs are in measuring blood glucose levels in PNLD, nor sufficient evidence of what the health benefits or utility ...

Despite high hopes, a drug that wipes out the namesake cell type associated with the disease eosinophilic esophagitis (EoE) doesn’t make patients feel better and doesn’t reverse tissue damage in their throats. Meanwhile, data show that a different drug that had previously been approved for use in adults and teens with EoE is also safe and effective for children under 12 who weigh at least 15 kg (about 33 pounds). The results of these clinical trials—plus an accompanying editorial—appear in the June 17, 2024, edition of The New England Journal of Medicine. “Together, these trials provide exciting advances in our understanding of, and treatment options for, ...

Vienna, Austria: An international team of researchers has identified specific bacteria in the gut that are associated with both mice and humans developing an addiction to food that can lead to obesity. They have also identified bacteria that play a beneficial role in preventing food addiction.   The research is presented today (Thursday) at the Federation of European Neuroscience Societies (FENS) Forum 2024 and is published simultaneously in the journal Gut [1,2].   Professor Elena Martín-García, from the Laboratory of Neuropharmacology-NeuroPhar in the Department of Medicine and Life Sciences at the Universitat ...

Almost 4,500 healthy and symptom-free over-60s were examined, with 28pc found to have heart valve disease  Age was found to be strongly associated with an increased incidence of significant heart valve disease  Study lays the foundation for more research into the potential role of screening in the elderly population  Peer-reviewed – Prospective Cohort Study - People  The sheer scale of undiagnosed heart valve disease in our ageing population has been revealed for the first ...

BLOOD CANCER Sylvester Expert Endorses FDA’s Recent Cancer Drug Approval Mikkael Sekeres, M.D., chief of the Division of Hematology at Sylvester, who specializes in treating leukemia and myelodysplastic syndromes (MDS), expressed his support for the Food and Drug Administration’s recent approval of the drug imetelstat. The drug, a telomerase inhibitor, treats cancer-related anemia in patients with lower-risk MDS. “With approval of imetelstat to treat myelodysplastic syndromes, we finally have another approach ...

COLUMBUS, Ohio – Adults who continuously played organized sports through their youth have fewer symptoms of anxiety and depression than those who never played or those who dropped out, a new study finds.   And those who dropped out of sports had poorer mental health than those who never played at all.   But many more people drop out of youth sports than play continuously until they are 18, said Chris Knoester, senior author of the study and professor of sociology at The Ohio State University.   “If you play and stick with sports, it’s ...