Malaria remains one of the world’s deadliest diseases. Each year malaria infections result in hundreds of thousands of deaths, with the majority of fatalities occurring in children under five. The Centers for Disease Control and Prevention recently announced that five cases of mosquito-borne malaria were detected in the United States, the first reported spread in the country in two decades. Fortunately, scientists are developing safe technologies to stop the transmission of malaria by genetically editing mosquitoes that spread the parasite that causes the disease. Researchers at the University of California San Diego led by Professor Omar Akbari’s laboratory have engineered ...

The Jackson Laboratory has won the 2023 Plan Sponsor of the Year award in the “Nonprofit Defined Contribution Plans $300 Million and Greater” category. The annual Plan Sponsor of the Year award is presented by PLANSPONSOR magazine, a professional publication that focuses on retirement programs. The award recognizes retirement plan sponsors that show a commitment to their participants’ financial health and retirement success. Winners were announced at the PLANSPONSOR National Conference in Orlando, Fla. on June 21. “Benefits such as ...

When asked to draw their local wildlife, 401 UK schoolchildren aged 7 to 11 most commonly drew mammals and birds, while amphibians and reptiles appeared in the fewest drawings, suggesting imbalances in children’s ecological awareness. Kate Howlett and Edgar Turner of the University of Cambridge, UK, present these findings in the open-access journal PLOS ONE on July 5, 2023. Prior research has shown that, overall, European and North American children’s access to green space has declined in recent decades, and they are becoming increasingly disconnected from nature. Access ...

Body mass index (BMI) may not increase mortality independently of other risk factors in adults, according to a new study published this week in the open-access journal PLOS ONE by Aayush Visaria and Soko Setoguchi of Rutgers University, US. The prevalence of overweight and obesity has risen dramatically over the last 25 years, and it is well-established that elevated BMI can contribute to several cardio-metabolic conditions. However, studies that have analyzed the association between BMI and all-cause mortality have been inconsistent. Most US studies have used data from the 1960s through 1990s and have included predominantly non-Hispanic White adults.  In the new work, the researchers ...

A study conducted at a retirement home in South Africa suggests that programs promoting interaction between residents and children may provide mental health benefits and could help manage common mental health conditions, such as anxiety and depression. Elizabeth Jane Earl and Debbie Marais of Stellenbosch University, South Africa, present these findings in the open-access journal PLOS ONE on July 5, 2023. Prior research suggests that common mental health conditions are often undiagnosed and untreated in retirement homes. Standard treatment for such conditions typically involves a combination of medication and non-pharmacological ...

The profile of scent compounds from a person’s hand can be used to predict their sex, according to a new study led by Kenneth Furton of Florida International University, publishing July 5 in the open-access journal PLOS ONE. In criminal investigations, dogs have long been used to reliably identify and track people based on their odor. But while human scent evidence from the field is well established, researchers have made little progress in analyzing human scent profiles in the lab. In the new study, researchers used an analysis technique called mass spectrometry to analyze ...

LA JOLLA, CALIF. – July 05, 2023 – New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease. The study found that a protein known to be active in immune cells is also active inside melanoma cells, helping promote tumor growth. The findings, published in the journal Science Advances, suggest that targeting this protein with new drugs may deliver a powerful double hit to melanoma tumors. “The ...

A study of 273 people found that brain circuits associated with depression were different between people with traumatic brain injury and those without TBI. The study suggests depression after TBI may not be the same as depression related to other causes. A new study led by Shan Siddiqi, MD, from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, suggests that depression after traumatic brain injury (TBI) could be a clinically distinct disorder rather than traditional ...

Billions of years ago, in the giant disk of dust, gas, and rocky material that orbited our young sun, larger and larger bodies coalesced to eventually give rise to the planets, moons, and asteroids we see today. Scientists are still trying to understand the processes by which planets, including our home planet, were formed. One way researchers can study how Earth formed is to examine the magmas that flow up from deep within the planet’s interior. The chemical signatures from these samples contain a record of the timing and the nature of the materials that came together to form ...

University of Queensland researchers have optimised a new technique to help forecast how volcanoes will behave, which could save lives and property around the world. Dr Teresa Ubide from UQ’s School of the Environment and a team of international collaborators have trialled a new application of the tongue-twisting approach: laser ablation inductively coupled plasma quadruple mass spectrometry. “It’s a mouthful, but this high-resolution technique offers clearer data on what’s chemically occurring within a volcano’s magma, which is fundamental to forecasting eruption patterns and changes,” Dr Ubide said. She described magma ...

New device shows promise in small animal studies Not only can it restore normal heart rhythms, it also can show which areas of the heart are functioning well and which areas are not After the device is no longer needed, it harmlessly dissolves inside the body, bypassing the need for extraction EVANSTON, Ill. — Nearly 700,000 people in the United States die from heart disease every year, and one-third of those deaths result from complications in the first weeks or months following a traumatic heart-related event. To help prevent those deaths, researchers at Northwestern ...

A team of astrophysicists at the University of Toronto (U of T) has revealed how the slow and steady lengthening of Earth’s day caused by the tidal pull of the moon was halted for over a billion years.  They show that from approximately two billion years ago until 600 million years ago, an atmospheric tide driven by the sun countered the effect of the moon, keeping Earth’s rotational rate steady and the length of day at a constant 19.5 hours.   Without this billion-year pause in the slowing of our planet’s rotation, our current 24-hour day would stretch to over 60 hours.  The ...

Article URL:  https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0287112 Article Title: Contributions of neighborhood social environment and air pollution exposure to Black-White disparities in epigenetic aging Author Countries: USA Funding: This work was supported by National Institute on Aging: R01-AG066152 (CM), R01- AG070885 (RB), P30-AG072979 (CM). Additional support includes Pennsylvania Department of Health (2019NF4100087335; CM), and Penn Institute on Aging (CM). National Institute on Aging: https://www.nia.nih.gov Pennsylvania Department of Health: https://www.health.pa.gov/Pages/default.aspx Penn Institute on Aging: https://www.med.upenn.edu/aging/. ...

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London and City University New York, published today (Wednesday 5 July) in JAMA Psychiatry, has found that the way childhood abuse and/or neglect is remembered and processed has a greater impact on later mental health than the experience itself. The authors suggest that, even in the absence of documented evidence, clinicians can use patients’ self-reported experiences of abuse and neglect to identify those at risk of developing mental health difficulties ...

DALLAS (SMU) – A large formation of granite discovered below the lunar surface likely was formed from the cooling of molten lava that fed a volcano or volcanoes that erupted early in the Moon’s history – as long as 3.5 billion years ago. A team of scientists led by Matthew Siegler, an SMU research professor and research scientist with the Planetary Science Institute, has published a study in Nature that used microwave frequency data to measure heat below the surface of a suspected volcanic ...

We interact with bits and bytes everyday – whether that’s through sending a text message or receiving an email.    There’s also quantum bits, or qubits, that have critical differences from common bits and bytes. These photons – particles of light – can carry quantum information and offer exceptional capabilities that can’t be achieved any other way. Unlike binary computing, where bits can only represent a 0 or 1, qubit behavior exists in the realm of quantum mechanics. Through “superpositioning,” a qubit can represent a 0, ...

Researchers using NASA’s James Webb Space Telescope have made major strides in confirming the source of dust in early galaxies. Observations of two Type II supernovae, Supernova 2004et (SN 2004et) and Supernova 2017eaw (SN 2017eaw), have revealed large amounts of dust within the ejecta of each of these objects. The mass found by researchers supports the theory that supernovae played a key role in supplying dust to the early universe. Dust is a building block for many things in our universe – planets in particular. As dust from dying stars spreads through space, it carries essential elements to help give birth to the next generation of stars ...

Danish researchers solve the mystery of how deadly virus hide in humans With a new method for examining virus samples researchers from the University of Copenhagen have solved an old riddle about how Hepatitis C virus avoids the human body's immune defenses. The result may have an impact on how we track and treat viral diseases in general. An estimated 50 million people worldwide are infected with with chronic hepatitis C. The hepatitis C virus can cause inflammation and scarring of the liver, and in the worst case, liver cancer.   Hepatitis C was discovered in 1989 and is one of the most studied viruses on the planet. Yet for decades, how it manages to evade the human immune ...

A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in humans. The findings are published as a Reviewed Preprint in eLife. Described by the editors as a fundamental study, the work provides a framework for using systems genetics approaches to dissect the complex mechanisms of gut physiology. The authors show how it is possible to use genetically diverse but well-characterised mice to interrogate intestinal inflammation and pinpoint genes influenced by the environment ...

Most people have at some point in their life suffered an intestinal infection or food poisoning forcing them to stay close to the bathroom. It is very uncomfortable. Most of the time, though, it passes quickly. But around 60,000-100,000 Danes suffer from a form of chronic diarrhoea called bile acid malabsorption or bile acid diarrhoea. It is a chronic condition characterised by frequent and sudden diarrhoea more than 10 times a day. Even though the disease is not life-threatening, it can seriously ...

PULLMAN, Wash. -- Kenyan patients who spend more than three days in the nation’s hospitals are more likely to harbor a form of bacteria resistant to one of the most widely used antibiotic classes, according to a recent study led by Washington State University. The research team found that 66% of hospitalized patients were colonized with bacteria resistant to third-generation cephalosporins, compared to 49% among community residents. Third-generation cephalosporins are typically used for serious infections, and resistance to these antibiotics ...

PITTSBURGH, July 5, 2023 — Children taking a prescription stimulant to manage symptoms of attention deficit hyperactivity disorder (ADHD) do not have more substance use or substance use disorder (SUD) as adolescents or young adults, according to a new study by researchers at the University of Pittsburgh School of Medicine. Published today in JAMA Psychiatry, the study may provide some reassurance to parents and clinicians who may be hesitant to prescribe ADHD stimulant medications for fear that they may lay the ...

“Listen, if there's one thing the history of evolution has taught us is that life will not be contained. Life breaks free. It expands to new territories, and it crashes through barriers painfully, maybe even dangerously, but . . . life finds a way,” said Ian Malcolm, Jeff Goldblum's character in Jurassic Park, the 1993 science fiction film about a park with living dinosaurs. You won't find any Velociraptors lurking around evolutionary biologist Jay T. Lennon's lab; however, Lennon, ...

-With pictures- In a new study, a group of scientists argue that the new high precision radiocarbon-based date set for Laacher See volcano eruption of 13,000 years before present is probably not correct. They argue that the correct age of the Laacher See volcano eruption is 12,880 years ago, 130 years after the date presented by Reinig et al., in 2021. The research team, which included scientists from Durham University, University of Oxford, Royal Holloway University of London, SYSTEMIQ Ltd. and Teesside University ...

CAMBRIDGE, MA — Engineering T cells to destroy cancer cells has shown success in treating some types of cancer, such as leukemia and lymphoma. However, it hasn’t worked as well for solid tumors. One reason for this lack of success is that the T cells target only one antigen (a target protein found on the tumors); if some of the tumor cells don’t express that antigen, they can escape the T cell attack. MIT researchers have now found a way to overcome that obstacle, using a vaccine that boosts the response of ...