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Chinese researchers achieve superionic hydride ion conduction at ambient temperatures

2023-04-05
Materials that can conduct negatively charged hydrogen atoms in ambient conditions would pave the way for advanced clean energy storage and electrochemical conversion technologies. A research team from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS) demonstrated a technique that enables a room-temperature all-solid-state hydride cell by introducing and exploiting defects in the lattice structure of rare earth hydrides. Their study was published in Nature on April 5. Solid materials ...

Therapy for babies with signs of autism cuts long-term disability costs

Therapy for babies with signs of autism cuts long-term disability costs
2023-04-05
New research evaluating the potential cost savings of a therapy for babies displaying early autism signs has predicted a three dollar return to Australia’s National Disability Insurance Scheme (NDIS) for every dollar invested in therapy.   Published in the prestigious JAMA Network Open, the health economic study drew on the results of a landmark multi-centre randomised clinical trial which reported the world’s first evidence that a therapy commenced in infancy (iBASIS-VIPP)* could reduce early developmental disability to the point where a childhood clinical autism diagnosis was two-thirds ...

CHOP researchers reveal complex assembly process involved in DNA virus replication

2023-04-05
Philadelphia, April 5, 2023—In a twist on the question, “Which came first, the chicken or the egg?”, scientists have long faced a similar question about how human adenovirus replicates: “Which comes first, assembly of the viral particle, or packaging of the viral genome?” Now, in a new study published today in Nature, researchers at Children’s Hospital of Philadelphia (CHOP) have answered that question, showing that viral proteins use a process called phase separation to coordinate production ...

Trends in suicidal thoughts, behaviors among veterans during pandemic

2023-04-05
About The Study: The prevalence of suicidal thoughts and behaviors has not increased for most U.S. veterans during the first three years of the COVID-19 pandemic. However, veterans with pre-existing loneliness, psychiatric distress, and lower purpose in life were at heightened risk of developing new-onset suicidal ideation and suicide planning during the pandemic. Evidence-based prevention and intervention efforts that target these factors may help mitigate suicide risk in this population. Authors: Ian C. Fischer, Ph.D., of the ...

Historical redlining, social determinants of health, and stroke prevalence in communities in New York City

2023-04-05
About The Study: This study found that historical redlining was associated with modern-day stroke prevalence in New York City independently of contemporary social determinants of health and community prevalence of some relevant cardiovascular risk factors.  Authors: Benjamin M. Jadow, B.A., of the Albert Einstein College of Medicine in Bronx, New York, is the corresponding author.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamanetworkopen.2023.5875) Editor’s Note: Please see the article ...

The unexpected contribution of medieval monks to volcanology

2023-04-05
By observing the night sky, medieval monks unwittingly recorded some of history’s largest volcanic eruptions. An international team of researchers, led by the University of Geneva (UNIGE), drew on readings of 12th and 13th century European and Middle Eastern chronicles, along with ice core and tree ring data, to accurately date some of the biggest volcanic eruptions the world has ever seen. Their results, reported in the journal Nature, uncover new information about one of the most volcanically active periods in Earth’s ...

Is artificial intelligence better at assessing heart health?

2023-04-05
Who can assess and diagnose cardiac function best after reading an echocardiogram: artificial intelligence (AI) or a sonographer?  According to Cedars-Sinai investigators and their research published today in the peer-reviewed journal Nature, AI proved superior in assessing and diagnosing cardiac function when compared with echocardiogram assessments made by sonographers.   The findings are based on a first-of-its-kind, blinded, randomized clinical trial of AI in cardiology led by investigators in the Smidt Heart Institute and the Division of Artificial Intelligence in Medicine at Cedars-Sinai.  “The results have immediate implications for ...

Gwangju Institute of Science and Technology researchers correlate Arctic warming to extreme winter weather in midlatitude and its future

Gwangju Institute of Science and Technology researchers correlate Arctic warming to extreme winter weather in midlatitude and its future
2023-04-05
Pictures of melting glaciers and stranded polar bears on shrinking sea ice in the Arctic are perhaps the most striking images that have been used to highlights the effects of global warming. However, they do not convey the full extent of the consequences of warmer Arctic. In recent years, there has been growing recognition of the Arctic’s role in driving extreme weather events in other parts of the world. While the Arctic has been warming at a rate twice as fast as the global average, winters in the midlatitude regions have experienced colder and more severe weather events. For instance, the winter of 2022-2023 saw record-breaking cold temperatures and snowfall ...

Finding a way to combat long COVID

2023-04-05
A new study has identified potential neurological biomarkers of long COVID-19 in nonhuman primates that may help physicians diagnose, monitor and treat this condition. Over 65 million people worldwide have developed long COVID after being infected with SARS-CoV-2, and cases are only becoming more common. Long COVID symptoms can last weeks, months or years. Even more perplexing is the fact that symptoms can vary widely between individuals and consist of any combination of fatigue, fever, chest pain, trouble breathing, neurological symptoms such as ...

Overview of orbital mechanics for space-based gravitational wave observatories

Overview of orbital mechanics for space-based gravitational wave observatories
2023-04-05
Gravitational waves (GWs) are “ripples in space-time”. The detection of gravitational waves (GWs) is critical to the understanding of the origin and evolution of stars, galaxies, and the Universe. At present, the laser interferometry is the most commonly use technology to detect GWs by measuring the phase change between two beams of coherent light. Due to the limitations of arm length, the ground-based GWs measurement is hard to detect the low-frequency GWs. While the space-based GWs observation is capable of longer arm length of the interferometer, the detection of GWs in space is expected to cover a greater number and variety of ...

Cracking the puzzle of lower respiratory tract infections in children

Cracking the puzzle of lower respiratory tract infections in children
2023-04-05
Lower respiratory tract infection (LRTI), which includes conditions such as pneumonia, has long been the leading cause of death from communicable agents and a leading cause of death in children worldwide. But despite its prevalence, LRTI is tricky for doctors to treat effectively because the current diagnostic approach often fails to conclusively determine whether an infection is present at all, and if so, what pathogen is causing it.  Now, in a study published April 3, 2023 in The Journal of Clinical Investigation, a team led by researchers at the Chan Zuckerberg Biohub San Francisco (CZ Biohub SF), UC San Francisco (UCSF), the University ...

Opening a new frontier: PdMo intermetallic catalyst for promoting CO2 utilization

Opening a new frontier: PdMo intermetallic catalyst for promoting CO2 utilization
2023-04-05
Being the most abundant and persistent greenhouse gas emitted, carbon dioxide (CO2) is the key driver of climate change. To address the pressing problems associated with climate change and fossil fuel depletion, scientists are looking for viable solutions that can minimize the amount of CO2 released into the atmosphere. One attractive solution to this problem is to convert atmospheric CO2 into more useful compounds. Towards this end, methanol ­- a raw material, fuel additive, and energy carrier, is widely being explored as a promising conversion option for CO2. Now, while various catalysts ...

SwRI, Tec de Monterrey award funding for sustainable manufacturing research

SwRI, Tec de Monterrey award funding for sustainable manufacturing research
2023-04-05
SAN ANTONIO — April 5, 2023 —Southwest Research Institute and Tecnológico de Monterrey (Tec de Monterrey) will jointly fund three research and development initiatives to advance sustainable manufacturing and technology in the United States and Mexico. The trio of projects are the first selected to receive support through the Sustainable Manufacturing Program, a transnational research and development collaboration established between SwRI and Tec de Monterrey — a private, nonprofit, independent university based in Monterrey, Mexico — in August 2022. The program provides grant opportunities funded ...

How were amino acids, one of the key building blocks of life, formed before the origin of life on Earth? Tiny particles from the near Earth asteroid Ryugu can help answer this profound question

How were amino acids, one of the key building blocks of life, formed before the origin of life on Earth? Tiny particles from the near Earth asteroid Ryugu can help answer this profound question
2023-04-05
Our solar system formed from a molecular cloud, which was composed of gas and dust that was emitted into the interstellar medium (ISM), a vast space between stars. On collapse of the molecular cloud, the early sun was formed, with a large disk of gas and dust orbiting it. The dusty material collided to produce rocky material that would eventually grow in size to give large bodies called planetesimals. The planetesimals that formed far enough from the sun, also contained large quantities of ice. The ice consisted of water and other volatile compounds, such as carbon monoxide (CO), carbon dioxide (CO2), methanol (CH3OH) and ammonia (NH3), as well as ...

Air pollution is linked to lower COVID-19 vaccine responses

2023-04-05
People exposed to higher levels of air pollution before the pandemic had lower antibody responses to COVID-19 vaccines, according to a study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by “la Caixa” Foundation, in collaboration with the Germans Trias i Pujol Research Institute (IGTP). In particular, exposure to fine particulate matter (PM2.5), nitrogen dioxide (NO2) and blank carbon (BC) was associated with about a 10% decrease in IgM and IgG antibody responses in people without prior infection. The findings, published in Environmental Health Perspectives, ...

More than a third of children worry at least once a week, with their tendency to worry progressing with age, according to national survey by Nemours KidsHealth(R)

2023-04-05
WILMINGTON, Del. (April 5, 2023) – More than one in three children ages 9 to 13 (37%) worry at least once a week, primarily about school (64%) and friendships (41%), with their tendency to worry progressing with age. Older children (age 13) are more likely than their younger counterparts to report feeling as though they will never stop worrying (48% vs. 22% for 9-year-olds). This is according to the results of What’s Worrying America’s Kids, a national survey conducted by The Harris Poll on behalf of Nemours KidsHealth. The survey results ...

TOS endorses global editorial on people-first language and pediatric obesity

2023-04-05
ROCKVILLE, Md.—The Obesity Society (TOS) has joined several European, US and Canadian obesity organizations in an editorial statement published in the journal Pediatric Obesity championing the use of people-first language for pediatric overweight and obesity to address weight stigma and bias. Professor David Thivel, president of the European Childhood Obesity Group and coordinator of the joint statement, said, "This paper emphasizes the importance of considering the use of people-first language when it comes to pediatric obesity, by all who work with, care for or support children and adolescents, in order to avoid stigmatization and to create an appropriate and optimal ...

Complications for procedure to open clogged pulmonary arteries decrease significantly

2023-04-05
For patients with high blood pressure in their pulmonary arteries caused by chronic blood clots, complications after a minimally invasive balloon angioplasty have decreased substantially over the last decade, a Michigan Medicine-led study finds.  Researchers examined over 7,500 cases of balloon pulmonary angioplasty for patients with chronic thromboembolic pulmonary hypertension, an elevated blood pressure in the pulmonary arteries due to persistent blockages known as CTEPH, between 2013 and 2022. The procedure, which is offered ...

New tool shows progress in fighting spread of invasive grass carp in Great Lakes

New tool shows progress in fighting spread of invasive grass carp in Great Lakes
2023-04-05
New research reveals the progress scientists at The University of Toledo are making in their ongoing efforts to capture and remove invasive grass carp from the Great Lakes. Researchers based at the UToledo Lake Erie Center created a new way to estimate the abundance of invasive “sleeper” species in freshwater ecosystems and help guide management strategies. Using data collected during their efforts to remove invasive grass carp from Lake Erie and its tributaries, the aquatic ecologists and environmental ...

Recent advances in space chemistry research

2023-04-05
Space is the great unknown — very few of us will ever experience what it’s like to visit another planet or moon, and so much is yet to be discovered. Below are some recent papers published in ACS journals that report advances toward understanding whether certain minerals, compounds or even life itself could form on other worlds. Reporters can request free access to these papers by emailing newsroom@acs.org. “Immunoanalytical Approach for Detecting and Identifying Ancestral Peptide Biomarkers in Early Earth Analogue Environments” Analytical Chemistry March 16, 2023 These authors reasoned that if they could analyze “resurrected” ...

Survey of allergists/immunologists reveals management of hereditary angioedema differs by region

2023-04-05
ARLINGTON HEIGHTS, Ill. (April 5, 2023) – Hereditary angioedema (HAE) is a disease that, due to its rare nature, can pose difficulties for both patients and medical professionals. A new survey of allergists/immunologists from the American College of Allergy, Asthma and Immunology (ACAAI) shows that diagnosing, treating and managing this condition can be challenging for patients and healthcare providers - including patients in rural areas. An article about the survey is published in Annals of Allergy, Asthma and Immunology, ACAAI’s scientific journal. HAE is caused by a genetic mutation, and there are different types. It is a hereditary disease. The symptoms of HAE ...

SynGAP Research Fund awards a collaborative grant to Tang Lab & AXONIS Therapeutics

SynGAP Research Fund awards a collaborative grant to Tang Lab & AXONIS Therapeutics
2023-04-05
PALO ALTO, Calif. (April 5, 2023) – SynGAP Research Fund (SRF), a 501(c)(3) public charity whose mission is to improve the quality of life for SYNGAP1 patients through the research and development of treatments, therapies and support systems, today announced they have awarded a $130,000 collaborative grant to the lab of Xing Tang, PhD at Boston Children's Hospital & AXONIS Therapeutics to investigate the treatment effects of KCC2-enhancing small molecule compounds in SYNGAP1 haploinsufficiency.  Principal Investigator of translational neuroscience at AXONIS, Dr. Kadam, has been working with the SRF community for many years. While at Johns Hopkins, she gave a popular SRF ...

Manganese in Central Valley water threatens fetuses and children

2023-04-05
Water in California’s Central Valley contains enough manganese to cause cognitive disabilities and motor control issues in children, and Parkinson’s-like symptoms in adults. A naturally occurring metal, manganese is found in water supplies throughout the world. It is regulated as a primary contaminant in many Southeast Asian countries where the climate causes it to leach into groundwater. However, in the U.S. it is regulated only as a secondary contaminant, meaning no maximum level is enforced.   A ...

Do altered gut microbes affect risk of attention-deficit/hyperactivity disorder?

2023-04-05
New research published in the Journal of Child Psychology and Psychiatry suggests that the microbial composition of the gut may affect a child’s susceptibility to attention-deficit/hyperactivity disorder (ADHD). The human gastrointestinal tract hosts a large population of microorganisms such as bacteria, viruses, and fungi. When investigators compared fecal samples from 35 children with ADHD and 35 healthy controls, samples from children with ADHD had higher levels of certain species of fungi and lower levels of other species.  In experiments with cells grown in the lab, one species in abundance in ...

Can a drug used to treat liver disease help prevent SARS-CoV-2 infections and lessen COVID-19 severity?

2023-04-05
SARS-CoV-2, the virus that causes COVID-19, attaches to a cellular receptor called angiotensin-converting enzyme 2 (ACE2), and activation of the farnesoid X receptor increases ACE2 expression. New research published in the Journal of Internal Medicine suggests that a drug that inhibits the farnesoid X receptor and is used to treat liver disease may decrease SARS-CoV-2 infections and reduce the severity of COVID-19. The study ran from March 2020 to February 2022 and included 3,214 patients with liver disease, half of whom were taking the drug, called ursodeoxycholic acid (UDCA). ...
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