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ARRS Annual Meeting: 4D flow MRI, 3D phantoms benefit atrial fibrillation patients

ARRS Annual Meeting: 4D flow MRI, 3D phantoms benefit atrial fibrillation patients
2023-04-17
Honolulu, HI | April 17, 2023—Findings from an award-winning Scientific Online Poster presented during the 2023 ARRS Annual Meeting at the Hawaiian Convention Center suggest that correctly occluded left atrial appendages (LAAs) could present maximal reduction in left atrial (LA) flow stasis and thrombogenicity, offering a clinical goal for the procedure in patients with atrial fibrillation. Pointing out the paucity of knowledge in atrial fibrillation (AF) populations regarding the actual flow dynamic changes before and after percutaneous left atrial appendage occlusion (LAAO), “we aimed to evaluate LA flow dynamics for pre-occluded, correctly occluded, and incorrectly ...

American Roentgen Ray Society (ARRS) Global Partners honor Jeong Min Lee, Korean Society of Radiology (KSR) President, with ARRS membership

American Roentgen Ray Society (ARRS) Global Partners honor Jeong Min Lee, Korean Society of Radiology (KSR) President, with ARRS membership
2023-04-17
Honolulu, HI | April 17, 2023—The Global Partner Society Program of the American Roentgen Ray Society (ARRS) is proud to announce that Jeong Min Lee, President of the Korean Society of Radiology (KSR) and professor of radiology at South Korea’s Seoul National University Hospital, will receive Honorary Membership in ARRS during the opening ceremony of the 2023 ARRS Annual Meeting in Honolulu, HI. As per Section 6 of the ARRS bylaws, honorary members of the ARRS shall be those who have rendered valuable service ...

Over 1 million lives saved across Europe by COVID-19 vaccines since the end of 2020

2023-04-17
**Note: the release below is from the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023, Copenhagen, 15-18 April). Please credit the conference if you use this story** COVID-19 vaccination directly saved at least 1,004,927 lives across Europe between December 2020 and March 2023, according to new research being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April). The new estimates by WHO/Europe and presented at the conference by Dr Margaux Meslé,  Epidemiologist at WHO/Europe highlight the striking ...

Long COVID incidence and severity no worse than post viral syndrome following seasonal influenza, study suggests

2023-04-17
**Note: the release below is from the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023, Copenhagen, 15-18 April). Please credit the conference if you use this story** In the highly vaccinated population of Queensland exposed to the Omicron variant, long COVID appears to manifest as a post-viral syndrome of no greater incidence or severity than seasonal influenza, according to new research being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April). The study by Queensland Health researchers suggests that despite the similarity of clinical outcomes ...

Metagenomic sequencing outperforms conventional tests to identify antimicrobial resistance in bloodstream infections

2023-04-17
Metagenomic sequencing can provide rapid and actionable antimicrobial resistance predictions to treat bloodstream infections much faster than conventional laboratory tests, and has the potential to save lives and better manage the use of antibiotics, according to new research being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April). The study led by Dr Kumeren Govender from the John Radcliffe Hospital, University of Oxford, ...

Effect of COVID-19 pandemic on mortality in people with intellectual disabilities extended beyond deaths from COVID itself

2023-04-17
Mortality from COVID-19 in people with intellectual disabilities five times higher than general population Study showed death rates for cancers, mental health disorders, circulatory disorders, external causes, and other natural causes in people with intellectual disabilities were higher during the COVID pandemic than pre-pandemic Observed effects likely to be due a range of factors including disruptions to care during pandemic PLEASE NOTE Embargo: 0030H CEST Copenhagen time Monday 17 April  *Note: ...

Connections in the brain involved in epileptic seizures identified

2023-04-17
Researchers at the UCL Queen Square Institute of Neurology have discovered a network of connections in the brain linked to seizures in people with epilepsy. The team believe that their findings, published in Brain, will help redesign neurological operations for patients whose epilepsy can’t be controlled by medication. By disconnecting certain pathways in the frontal lobe, patients may be able to enjoy long-lasting freedom from seizures. There are 500,000 people in the UK with epilepsy and 50 million people have the condition worldwide. But one in three cannot ...

New details of Tully monster revealed

New details of Tully monster revealed
2023-04-17
For more than half a century, the Tully monster (Tullimonstrum gregarium), an enigmatic animal that lived about 300 million years ago, has confounded paleontologists, with its strange anatomy making it difficult to classify. Recently, a group of researchers proposed a hypothesis that Tullimonstrum was a vertebrate similar to cyclostomes (jawless fish like lamprey and hagfish). If it was, then the Tully monster would potentially fill a gap in the evolutionary history of early vertebrates. Studies ...

Environmental toxin PCB found in deep sea trench

Environmental toxin PCB found in deep sea trench
2023-04-17
PCB has been banned in most countries since the 1970s, but that doesn't mean it no longer exists. Now, deep-sea researchers report that they have found PCB at the bottom of the Atacama Trench in the Pacific Ocean. During their expedition to the deep-sea trench, the research team retrieved sediment cores and analyzed them for PCB occurrences at five different locations in the trench. All the samples of surface sediment analyzed contained PCB. The study, led by Professor Anna Sobek from the Department of Environmental Science at Stockholm University and Professor Ronnie N. Glud, director of the Danish Center for Hadal Research at ...

KERI accredited as an inspection body by ACCREDIA for electrical equipment

KERI accredited as an inspection body by ACCREDIA for electrical equipment
2023-04-17
The Korea Electrotechnology Research Institute (KERI, President Kim Nam-Kyun), an internationally accredited testing and certification body for electrical equipment, has been accredited as a Type A Inspection Body by ACCREDIA, an international accreditation body in Italy. An Inspection Body verifies the performance and quality of products, and an Accreditation Body attests and supervises Inspection Bodies to ensure their competence and impartiality. ACCREDIA is a world leader in accreditation for electrical equipment. It is a full member of the International Accreditation ...

NCCS research luminaries conferred distinguished professorships in pathology and colorectal surgery

2023-04-17
Singapore, 16 April 2023 – The SingHealth Duke-NUS Academic Medical Centre (AMC) announced that Distinguished Professorships have been awarded to two research luminaries from the National Cancer Centre Singapore (NCCS). The Professorships are the highest honour bestowed upon faculty members by the SingHealth Duke-NUS AMC. Professor Teh Bin Tean, Deputy Chief Executive Officer (Research), NCCS, and Professor, Duke-NUS Medical School, was conferred the Tan Yew Oo Professorship in Pathology and Associate Professor Iain Tan Bee Huat, Division Director of Research and Senior Consultant, Division of Medical Oncology, ...

Lower risk of severe illness and death in newborns of low-income immigrant than Canadian-born females

2023-04-17
Newborns of non-refugee immigrant females are at overall lower risk of serious illness and death than those of Canadian-born females in low-income neighbourhoods in Ontario, according to new research published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221711. Previous research has looked at the risk of adverse outcomes for newborns in low- v. high-income neighbourhoods, but there is little evidence on the respective risks for immigrant and nonimmigrant mothers living in similar low-income neighbourhoods. Both immigration status and living in a low-income ...

Income rank linked to experience of physical pain, irrespective of whether in a rich or poor country, study suggests

2023-04-17
A new study of worldwide polling data suggests that a person’s income rank relative to their peers is linked to their experience of physical pain, with a lower income rank linked to a higher likelihood of experiencing pain. It is the first time such a relationship has been shown. The study found the link to persist, to the same degree, irrespective of whether the person lives in a rich country or a poor country. Income rank is the position of an individual’s absolute personal income amount in a list of those amounts ordered from lowest to highest.  The higher the position in the list, the higher the income ...

Treatment with immunotherapy alone produces ‘exceptional’ response rates in some melanoma patients

2023-04-16
COLUMBUS, Ohio ­– Data from a national clinical trial shows that a striking 89% of patients with desmoplastic melanoma responded to immunotherapy (pembrolizumab) alone, suggesting that many patients could avoid the risk for toxicity from combination therapies and achieve cancer control with this approach to treatment. Desmoplastic melanoma is a subset of melanoma skin cancer that is caused by high levels of ultraviolet (UV) radiation damage and, therefore, a high number of tumor mutations that all contribute to aggressive ...

SWOG S1512 trial sees high response rate to pembrolizumab in patients with unresectable desmoplastic melanoma

2023-04-16
Close to 90 percent of patients with unresectable (inoperable) desmoplastic melanoma, a rare form of skin cancer, saw their cancer improve after treatment with the immunotherapy drug pembrolizumab in a recent clinical trial. These results from the S1512 trial conducted by the SWOG Cancer Research Network, a group funded by the National Cancer Institute (NCI), are being delivered in an oral presentation at the clinical trials plenary session of the 2023 annual meeting of the American Association for Cancer Research (AACR) in Orlando, Florida, on April 16th. The S1512 ...

AACR: YAP/TEAD inhibitor VT3989 is well tolerated and shows antitumor activity in advanced mesothelioma and NF2-mutant cancers

AACR: YAP/TEAD inhibitor VT3989 is well tolerated and shows antitumor activity in advanced mesothelioma and NF2-mutant cancers
2023-04-16
ABSTRACT: CT006 ORLANDO, Fla. ― The first-in-class YAP/TEAD inhibitor VT3989 was well tolerated with durable antitumor responses in patients with advanced malignant mesothelioma and other tumors with NF2 mutations, according to results of a Phase I trial led by researchers at The University of Texas MD Anderson Cancer Center. The first-in-human study was presented today at the American Association for Cancer Research (AACR) Annual Meeting 2023. Seven of 69 patients had radiological partial responses that persisted up to at least 21 months, indicating tumor shrinkage, while 34 had stable disease. Patient benefit was observed in patients with both mesothelioma ...

AACR: Penn Medicine preclinical study identifies new target for recurrent ovarian cancer

2023-04-16
ORLANDO – Despite recent advances, ovarian cancer remains the fifth leading cause of cancer-related deaths among women, and there’s a critical need for new treatment options, especially for advanced cancers that grow back after standard of care treatment. Results from a preclinical study, led by researchers from the Perelman School of Medicine at the University of Pennsylvania, verified a new target for drug-resistant ovarian cancer and provided data to support a treatment approach that is already making its way into clinical trials. Sarah Gitto, PhD, an instructor of Pathology and Laboratory ...

Adding new vaccine type to leading immunotherapy dramatically reduced melanoma recurrence

2023-04-16
VIDEO OF RESEARCHER AND PATIENT COMMENTARY IS AVAILABLE AT: https://bcove.video/3mxxASq   The combination of an experimental mRNA vaccine with an immunotherapy reduced the likelihood of melanoma recurring or causing death by 44% when compared to immunotherapy alone, a new clinical trial shows. Led by researchers at NYU Langone Health and its Perlmutter Cancer Center, the randomized phase 2b trial involved men and women who had surgery to remove melanoma from lymph nodes or other organs and were at high risk of the disease returning in sites distant from the original cancer.            ...

AACR: Lung cancer outcomes significantly improved with immunotherapy-based treatment given before and after surgery

AACR: Lung cancer outcomes significantly improved with immunotherapy-based treatment given before and after surgery
2023-04-16
ABSTRACT: CT005  ORLANDO, Fla. ― A regimen of pre-surgical immunotherapy and chemotherapy followed by post-surgical immunotherapy significantly improved event-free survival (EFS) and pathologic complete response (pCR) rates compared to chemotherapy alone for patients with operable non-small cell lung cancer (NSCLC), according to Phase III trial results presented today by researchers from The University of Texas MD Anderson Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2023.   The ...

A new breakthrough in Alzheimer disease research - visualizing reactive astrocyte-neuron interaction

A new breakthrough in Alzheimer disease research - visualizing reactive astrocyte-neuron interaction
2023-04-16
Recently, a team of South Korean scientists led by Director C. Justin LEE of the Center for Cognition and Sociality within the Institute for Basic Science made a new discovery that can revolutionize both the diagnosis and treatment of Alzheimer’s Disease. The group demonstrated a mechanism where the astrocytes in the brain uptake elevated levels of acetates, which turns them into hazardous reactive astrocytes. They then went on further to develop a new imaging technique that takes advantage of this mechanism to directly observe the astrocyte-neuron interactions. Alzheimer’s disease (AD), one of ...

Statin use is associated with lower risk of stroke in patients with atrial fibrillation

2023-04-16
Barcelona, Spain – 16 April 2023:  A region-wide study in more than 50,000 patients with atrial fibrillation has found reduced risks of stroke and transient ischaemic attack in those who started statins within a year of diagnosis compared with those who did not. The findings are presented at EHRA 2023, a scientific congress of the European Society of Cardiology (ESC).1   “Our study indicates that taking statins for many years was even more protective against stroke than short-term use,” said study author Ms. Jiayi Huang, a PhD student at the University of Hong Kong, China.   Atrial fibrillation is the most common ...

ARRS Annual Meeting: 3D SVR MRI helps delineate fetal optic nerve pathway

ARRS Annual Meeting: 3D SVR MRI helps delineate fetal optic nerve pathway
2023-04-16
Honolulu, HI | April 16, 2023—An award-winning Scientific Online Poster presented during the 2023 ARRS Annual Meeting on the island of Oahu explained how the novel technique of three-dimensional (3D) slice-to-volume (SVR) MRI allows for precise delineation and measurement of the fetal optic pathway (FOP). Noting the limited fetal presentation and low reproducibility of ultrasound-based techniques, as well as conventional MRI’s inconsistencies in FOP visualization due to low resolution (i.e., large slice thickness), “our preliminary results nevertheless demonstrate the promises and utility of this technique,” said Eric Juang, MS, of Creighton University ...

Erik Paulson gaveled in as president of American Roentgen Ray Society (ARRS)

Erik Paulson gaveled in as president of American Roentgen Ray Society (ARRS)
2023-04-16
Honolulu, HI | April 16, 2023—Erik K. Paulson, MD, chair of the radiology department at Duke University, has been named the 123rd President of the American Roentgen Ray Society (ARRS) during the opening ceremony of the 2023 ARRS Annual Meeting in Honolulu, HI. “I am absolutely honored and delighted to serve as the President of our country’s oldest radiology society, a society whose sweet spot is member education,” Dr. Paulson said in his ARRS Annual Meeting opening remarks at ...

UK strep A research shows highest incidence of invasive disease has shifted from the most deprived groups to the second most affluent group

2023-04-16
  **Note: the release below is from the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023, Copenhagen, 15-18 April). Please credit the conference if you use this story** Measures introduced to reduce transmission of COVID-19 infections during 2020-2021 suppressed transmission of group A streptococcal (GAS) infections, particularly in children. Following the lifting of public health restrictions in the UK in Feb-2022, Group A Streptococcus presentations – including scarlet fever and invasive Group A Strep – rose significantly in England, although iGAS still remained very ...

Surge of strep A infections, including more dangerous invasive type, has affected Denmark since late 2022, especially in the elderly

2023-04-16
**Note: the release below is from the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023, Copenhagen, 15-18 April). Please credit the conference if you use this story** During the 2022-2023 winter season Denmark experienced a surge in infections caused by group A streptococci (GAS), including the more dangerous, invasive types of infections (iGAS). Incidence of iGAS is highest among the elderly, but the largest relative increase from previous seasons was seen among children. The study is being presented to the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2023, Copenhagen, ...
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