Two-dimensional (2D) materials with a single-layer thickness retaining magnetic order in atomically thin limit began to increase their scientific and technological significance after the successful synthesis of graphene and later investigations of van der Waals materials. CrBr3 has been known since the 60s as a van der Waals ferromagnet. Hansen, Tsubokawa, and Dillon have pioneered the work on magnetism in this compound. However, it has only recently been established that CrBr3 exhibits ferromagnetism when exfoliating to several layers and monolayers while ...

The design, interpretation, and enforcement of county and municipal laws significantly affect local public health. But accessing those laws can be difficult. A study by Indiana University researchers found that unlike Indiana state laws, which are collected, catalogued by topic, and kept regularly updated in centralized, publicly available electronic databases, laws in about half of all Indiana counties were not online, or if they were online, they weren't necessarily up to date. This means that in Indiana, there is no comprehensive, up-to-date central source that can be used to study how different local governments respond to similar health-related ...

A small proportion of women who receive anti-estrogen treatment after breast cancer surgery have worse outcomes. This is associated with mutations in the estrogen receptor gene, according to a study from Lund University now published in JNCI Cancer Spectrum. "If our results are confirmed in further studies, it would be relevant to screen for these resistance mutations already at diagnosis, and then consider other treatment options that could work better for patients with mutated tumors," says Lao Saal, who led the study, the largest of its kind on resistance mutations in the estrogen receptor in primary breast cancer. Breast cancer is the most common ...

Inspired by nature, the researchers developing a new load-bearing material Engineers have developed a new material that mimics human cartilage - the body's shock absorbing and lubrication system, and it could herald the development of a new generation of lightweight bearings. Cartilage is a soft fibrous tissue found around joints which provides protection from the compressive loading generated by walking, running or lifting. It also provides a protective, lubricating layer allowing bones to pass over one another in a frictionless way. For years, scientists have been trying to create a synthetic material with the properties of cartilage. ...

Several weeks following the publication of the large real-world Covid-19 vaccine effectiveness study by the Clalit Research Institute in Collaboration with Harvard University in the New England Journal of Medicine (NEJM), additional results focusing on vaccine effectiveness in specific sub-populations have now been published. While the original publication demonstrated the effectiveness of the Pfizer-BioNTech mRNA vaccine in the general population, outstanding questions remained regarding vaccine effectiveness in specific sub-populations of interest, including the elderly, multi-morbid ...

An international team led by a Skoltech researcher has developed a method of fabrication for biodegradable polymer microcapsules, made more efficient by turning to an unusual source of inspiration - traditional Russian dumpling, or pelmeni, making. The two papers were published in Materials and Design and ACS Applied Materials and Interfaces. Micro-sized capsules, which can be tailored to a variety of purposes, have proven very useful in targeted delivery of drugs and other bioactive compounds. To ensure optimal functioning, these have to be designed and manufactured with precision and in particular shapes, as non-spherical capsules turned out to be more efficient and effective than spherical ones. "Non-spherical capsules could have side directed release ...

Students who have been exposed to interpersonal trauma —  physical assault, sexual assault or unwanted sexual experiences — prior to college are more likely to engage in risky alcohol use. But romantic relationships mitigate these effects of trauma on a student’s drinking behavior, according to a new study led by Virginia Commonwealth University researchers. The study investigates whether romantic relationships might play a role in mitigating or exacerbating the effects of trauma exposure on alcohol use among college students. It found that students who experienced interpersonal trauma during college consumed more alcohol than those without interpersonal trauma exposure, and that their drinking was more pronounced for those in a relationship with a partner with ...

A good night's sleep is essential for a healthy body and mind, for when we sleep is when the body resets, repairs, and refreshes itself. A lot of people, however, have trouble falling or staying asleep, a condition known as insomnia that affects up to 30% of the population. It is usually caused by an underlying psychiatric or clinical condition and is associated with a poorer quality of life. Recent genome wide analyses have revealed that a gene MEIS1 is linked with insomnia. Interestingly, this gene has also been implicated in restless leg syndrome and iron-deficiency anemia (IDA), the latter ...

For corn, using dairy manure and legume cover crops in crop rotations can reduce the need for inorganic nitrogen fertilizer and protect water quality, but these practices also can contribute to emissions of nitrous oxide -- a potent greenhouse gas. That is the conclusion of Penn State researchers, who measured nitrous oxide emissions from the corn phases of two crop rotations -- a corn-soybean rotation and a dairy forage rotation -- under three different management regimens. The results of the study offer clues about how dairy farmers might reduce the amount of nitrogen fertilizer they apply to corn crops, saving money and contributing less to climate change. The results are important because although nitrous ...

SAN FRANCISCO, CA--April 21, 2021--Not all cancer cells within a tumor are created equal; nor do all immune cells (or all liver or brain cells) in your body have the same job. Much of their function depends on their location. Now, researchers at Gladstone Institutes, UC San Francisco (UCSF), and UC Berkeley have developed a more efficient method than ever before to simultaneously map the specialized diversity and spatial location of individual cells within a tissue or a tumor. The technique, called XYZeq, was described online this week in the journal Science Advances. It involves segmenting a tissue into a microscopic grid before analyzing RNA from intact cells in each square of the grid, in order to gain a clear understanding of how each particular cell is functioning within ...

In rare cases, people who have been fully vaccinated against COVID and are immune to the virus can nevertheless develop the disease. New findings from The Rockefeller University now suggest that these so-called breakthrough cases may be driven by rapid evolution of the virus, and that ongoing testing of immunized individuals will be important to help mitigate future outbreaks. The research, published this week in the New England Journal of Medicine, reports results from ongoing monitoring within the Rockefeller University community where two fully vaccinated individuals tested positive for the coronavirus. Both had received two doses of either the Moderna or the Pfizer vaccine, with the second dose occurring more than two weeks before the positive test. One person was initially ...

Fast reactions to future events are crucial. A boxer, for example, needs to respond to her opponent in fractions of a second in order to anticipate and block the next attack. Such rapid responses are based on estimates of whether and when events will occur. Now, scientists from the Max Planck Institute for Empirical Aesthetics (MPIEA) and New York University (NYU) have identified the cognitive computations underlying this complex predictive behavior. How does the brain know when to pay attention? Every future event carries two distinct kinds of uncertainty: ...

COLUMBUS, Ohio - In the continuing search for dark matter in our universe, scientists believe they have found a unique and powerful detector: exoplanets. In a new paper, two astrophysicists suggest dark matter could be detected by measuring the effect it has on the temperature of exoplanets, which are planets outside our solar system. This could provide new insights into dark matter, the mysterious substance that can't be directly observed, but which makes up roughly 80% of the mass of the universe. "We believe there should be about 300 billion exoplanets that are waiting to be discovered," said Juri Smirnov, a fellow at The Ohio ...

In the arms race "mankind against bacteria", bacteria are currently ahead of us. Our former miracle weapons, antibiotics, are failing more and more frequently when germs use tricky maneuvers to protect themselves from the effects of these drugs. Some species even retreat into the inside of human cells, where they remain "invisible" to the immune system. These particularly dreaded pathogens include multi-resistant staphylococci (MRSA), which can cause life-threatening diseases such as sepsis or pneumonia. In order to track down the germs in their hidouts and eliminate them, a team of researchers from Empa and ETH Zurich is now developing nanoparticles that use a completely different mode ...

BOSTON - For many patients with localized lung cancer (non-small-cell lung carcinoma and small cell lung carcinoma), high-dose radiation with concurrent chemotherapy is a potential cure. Yet this treatment can cause severe, acute inflammation of the esophagus (esophagitis) in about one in five patients, requiring hospitalization and placement of a feeding tube. A team of radiation oncologists at Mass General Cancer Center demonstrate in an early clinical trial that the radiation beam can be carefully "sculpted" to deliver the majority of a radiation dose directly to the tumor while effectively sparing tissues in the side of the ...

Ann Arbor, April 22, 2021 - Using nearly a year of anonymous geolocation data from 15-17 million cell phone users in 3,037 United States counties, investigators have found that individuals with lower income per capita or greater Republican orientation were associated with significantly reduced social distancing throughout the study period from March 2020 through January 2021. Their findings are reported in the American Journal of Preventive Medicine, published by Elsevier. The associations persisted after adjusting for a variety of county-level demographic and socioeconomic characteristics. Other county-level characteristics, such as the share of Black and Hispanic residents, were also associated ...

Topological photonics has attracted a lot of attention recently. The application of topological band theory to photonics not only opens the door to novel devices, but also stimulates the exploration of new topological phases. In the photonic regime, symmetries that are unique to electromagnetic (EM) waves can intrinsically protect the band degeneracies in the momentum space. Topological systems realized using such symmetries are uniquely "photonic", having no counterparts in electronic or phononic systems. Among various topological features in momentum space, nodal chain is a special ...

Guilt and social pressure lead people to underreport COVID-19 protocol violations, according to study of experimental data across 12 countries. Article Title: A guilt-free strategy increases self-reported non-compliance with COVID-19 preventive measures: Experimental evidence from 12 countries Funding: J.-F. Daoust acknowledges the financial support from SSPS Open Access (University of Edinburgh). M. Foucault and S. Brouard acknowledge the financial support from ANR - REPEAT grant (Special COVID-19), CNRS, Fondation de l'innovation politique, as well as regions Nouvelle-Aquitaine and Occitanie. Richard Nadeau and Éric Bélanger acknowledge the financial support from the Social Sciences and Humanities Research Council (SSHRC/CRSH). M. Becher gratefully acknowledges ...

Unconventional superconductors contain a number of exotic phases of matter that are thought to play a role, for better or worse, in their ability to conduct electricity with 100% efficiency at much higher temperatures than scientists had thought possible - although still far short of the temperatures that would allow their wide deployment in perfectly efficient power lines, maglev trains and so on. Now scientists at the Department of Energy's SLAC National Accelerator Laboratory have glimpsed the signature of one of those phases, known as pair-density waves or PDW, and confirmed that it's intertwined with another phase known as charge density wave (CDW) stripes - wavelike patterns of higher and lower ...

Substantial proportions of pregnant and postpartum women scored high for symptoms of anxiety, depression, loneliness and post-traumatic stress in relation to COVID-19 in a survey carried out in May and June 2020, according to a new study published this week in the open-access journal PLOS ONE by Karestan Koenen and Archana Basu of Harvard T.H. Chan School of Public Health, US, and colleagues. Pregnant and postpartum women face unique challenges during the COVID-19 pandemic that may put them at elevated risk of mental health problems. These include concerns about ...

Time seems to pass more slowly in the UK COVID-19 lockdown - especially for people who are depressed, shielding or dissatisfied with social interactions INFORMATION: Article Title: Distortions to the passage of time during England's second national lockdown: A role for depression Funding: The author received no specific funding for this work. Competing Interests: The authors have declared that no competing interests exist. Article URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0250412 ...

Survey of 3,536 healthcare workers suggests 67 percent are suffering burnout, but people who receive frequent COVID-19 tests are less likely to be burned out. INFORMATION: Article Title: Determinants of burnout and other aspects of psychological well-being in healthcare workers during the Covid-19 pandemic: A multinational cross-sectional study Funding: JK has received an educational grant from Johnson and Johnson. Competing Interests: JK has received an educational grant from Johnson and Johnson. This does not alter our adherence to PLOS ONE ...

Kobe University Hospital's Dr. NISHIMORI Makoto and Project Assistant Professor KIUCHI Kunihiko et al. (of the Division of Cardiovascular Medicine, Department of Internal Medicine) have developed an AI that uses multiple kinds of test data to predict the location of surplus pathways in the heart called 'accessory pathways', which cause the heart to beat irregularly. In this study, the researchers were able to improve diagnosis accuracy by having the AI learn from two completely different types of test results- electrocardiography (ECG) data and X-ray images. It is hoped that this methodology can be applied to other disorders based upon the successful results of this research. These ...

Stimulus-responsive supramolecular structures have emerged as an alternative to conventional ones, owing to their applications in sensing, drug delivery, and switchable memory systems. Now, scientists at Tokyo Institute of Technology explore the hydrostatic-pressure response of "foldamers"--artificial molecules that mimic protein folding--and report a shift in their preferred conformation with changing pressure, demonstrating hydrostatic pressure-enabled dynamic control. The finding opens doors to future development of pressure-sensitive foldamers and artificial materials. Most, if not all, biological systems are extremely complex and often rely on interactions traditional ...

Animals use their sense of smell to navigate the world--to find food, sniff out mates and smell danger. But when a hungry animal smells food and a member of the opposite sex at the same time, what makes dinner the more attractive option? Exactly what is it about the odor of food that says, "Choose me?" Research by investigators at Harvard Medical School illuminates the neurobiology that underlies food attraction and how hungry mice choose to pay attention to one object in their environment over another. In their study, published March 3 in Nature, Stephen Liberles and co-author Nao Horio, identified the pathway that promotes attraction ...