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Florida Python Hunters May Have a New Tool Thanks to Optics Research at UCF

Florida Python Hunters May Have a New Tool Thanks to Optics Research at UCF
2021-06-10
Just as the governor announced the start of python hunting season in Florida this month, researchers at the University of Central Florida have published a first- of-its-kind study that shows that near-infrared (NIR) spectrum cameras can help hunters more effectively track down these invasive snakes, especially at night. The snakes, which can reach 26 feet in length and 200 pounds, have invaded the Everglades in Florida -- threatening native species and disrupting the ecosystem. The number of common native species observed in the Everglades since the snakes were first discovered in the 1990s dropped in some species by 90% through 2010, according ...

Novel liquid crystal metalens offers electric zoom

2021-06-10
ITHACA, N.Y. - Researchers from Cornell University's School of Applied and Engineering Physics and Samsung's Advanced Institute of Technology have created a first-of-its-kind metalens - a metamaterial lens - that can be focused using voltage instead of mechanically moving its components. The proof of concept opens the door to a range of compact varifocal lenses for possible use in many imaging applications such as satellites, telescopes and microscopes, which traditionally focus light using curved lenses that adjust using mechanical parts. In some applications, moving traditional glass or plastic lenses ...

Butterflies and moths have difficulty adjusting to a rapidly changing climate

Butterflies and moths have difficulty adjusting to a rapidly changing climate
2021-06-10
Climate change exerts great pressure for change on species and biodiversity. A recent study conducted by the University of Helsinki and the Finnish Environment Institute indicates that the few moth and butterfly species (Lepidoptera) capable of adjusting to a changing climate by advancing their flight period and moving further north have fared the best in Finland. In contrast, roughly 40% of Lepidoptera species have not been able to respond in either way, seeing their populations decline. Climate change is bringing about rapid change in Finnish nature - can species keep up with the pace? Adjusting to climate change can manifest through earlier phenology such as moth and butterfly flight periods, bird nesting, or ...

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

Forget me not: Novel target shows promise in treating Alzheimers and related dementias
2021-06-10
Researchers remain perplexed as to what causes dementia and how to treat and reverse the cognitive decline seen in patients. In a first-of-its-kind study, researchers at the Medical University of South Carolina (MUSC) and Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School discovered that cis P-tau, a toxic, non-degradable version of a healthy brain protein, is an early marker of vascular dementia (VaD) and Alzheimer's disease (AD). Their results, published on June 2 in Science Translational Medicine, define the molecular mechanism that causes an accumulation of this toxic protein. Furthermore, they showed that ...

Music listening near bedtime disruptive to sleep, Baylor study finds

Music listening near bedtime disruptive to sleep, Baylor study finds
2021-06-10
WACO, Texas (June 9, 2021) - Most people listen to music throughout their day and often near bedtime to wind down. But can that actually cause your sleep to suffer? When sleep researcher Michael Scullin, Ph.D., associate professor of psychology and neuroscience at Baylor University, realized he was waking in the middle of the night with a song stuck in his head, he saw an opportunity to study how music -- and particularly stuck songs -- might affect sleep patterns. Scullin's recent study, published in Psychological Science, investigated the relationship between music listening and sleep, focusing on a rarely-explored mechanism: involuntary musical imagery, or "earworms," when a song or tune replays ...

Study identifies how COVID-19 linked to Alzheimer's disease-like cognitive impairment

Study identifies how COVID-19 linked to Alzheimers disease-like cognitive impairment
2021-06-10
June 10, 2021, CLEVELAND: A new Cleveland Clinic-led study has identified mechanisms by which COVID-19 can lead to Alzheimer's disease-like dementia. The findings, published in Alzheimer's Research & Therapy, indicate an overlap between COVID-19 and brain changes common in Alzheimer's, and may help inform risk management and therapeutic strategies for COVID-19-associated cognitive impairment. Reports of neurological complications in COVID-19 patients and "long-hauler" patients whose symptoms persist after the infection clears are becoming more common, suggesting that SARS-CoV-2 (the virus that causes COVID-19) may have lasting effects on brain function. However, it is not yet well understood how the virus leads to neurological issues. "While some studies suggest ...

Fast heart, slow heart: Changes in the molecular motor myosin explain the difference

2021-06-10
The human heart contracts about 70 times per minute, while that of a rat contracts over 300 times; what accounts for this difference? In a new study publishing 10th June in the open-access journal PLOS Biology, led by Michael Geeves and Mark Wass of the University of Kent and Leslie Leinwand from the University of Colorado Boulder, reveal the molecular differences in the heart muscle protein beta myosin that underly the large difference in contraction velocity between the two species. Myosin is a "molecular motor" - an intricate nanomachine that forms the dynamic core of a muscle's contractile machinery, burning ...

Astronomy meets pathology to identify predictive biomarkers for cancer immunotherapy

Astronomy meets pathology to identify predictive biomarkers for cancer immunotherapy
2021-06-10
Pairing sky-mapping algorithms with advanced immunofluorescence imaging of cancer biopsies, researchers at The Mark Foundation Center for Advanced Genomics and Imaging at Johns Hopkins University and the Bloomberg~Kimmel Institute for Cancer Immunotherapy developed a robust platform to guide immunotherapy by predicting which cancers will respond to specific therapies targeting the immune system. A new platform, called AstroPath, melds astronomic image analysis and mapping with pathology specimens to analyze microscopic images of tumors. Immunofluorescent imaging, using antibodies with fluorescent tags, enables researchers to visualize multiple cellular proteins simultaneously and determine their pattern and strength of expression. Applying AstroPath, ...

Scientists uncover the mysteries of how viruses evolve

Scientists uncover the mysteries of how viruses evolve
2021-06-10
The team say their findings have implications for the treatment of viruses in future. Researchers from the Universities of York and Leeds, collaborating with the Hilvert Laboratory at the ETH Zürich, studied the structure, assembly and evolution of a 'container' composed of a bacterial enzyme. The study - published in the journal Science - details the structural transformation of these virus-like particles into larger protein 'containers'. It also reveals that packaging of the genetic cargo in these containers becomes more efficient during the later stages of evolution. They show that this is because the genome inside evolves hallmarks of a mechanism widely ...

Study on plant roots challenges nature of ecological trade-offs

2021-06-10
The specific traits of a plant's roots determine the climatic conditions under which a particular plant prevails. A new study led by the University of Wyoming sheds light on this relationship -- and challenges the nature of ecological trade-offs. Daniel Laughlin, an associate professor in the UW Department of Botany and director of the Global Vegetation Project, led the study, which included researchers from the German Centre for Integrative Biodiversity Research in Leipzig, Germany; Leipzig University; and Wageningen University & Research in Wageningen, Netherlands. "We found that root traits can explain species distributions across the planet, which has never been attempted ...

Pinpointing how cancer cells turn aggressive

Pinpointing how cancer cells turn aggressive
2021-06-10
It's often cancer's spread, not the original tumor, that poses the disease's most deadly risk. "And yet metastasis is one of the most poorly understood aspects of cancer biology," says Kamen Simeonov, an M.D.-Ph.D. student at the University of Pennsylvania Perelman School of Medicine. In a new study, a team led by Simeonov and School of Veterinary Medicine professor Christopher Lengner has made strides toward deepening that understanding by tracking the development of metastatic cells. Their work used a mouse model of pancreatic cancer and cutting-edge techniques to trace the lineage and gene expression patterns of individual cancer cells. They found a spectrum of aggression in the cells that arose, with cells ...

How butterflies make transparent wings: MBL scientists see the invisible

How butterflies make transparent wings: MBL scientists see the invisible
2021-06-10
WOODS HOLE, Mass. -- Many animals have evolved camouflage tactics for self-defense, but some butterflies and moths have taken it even further: They've developed transparent wings, making them almost invisible to predators. A team led by Marine Biological Laboratory (MBL) scientists studied the development of one such species, the glasswing butterfly, Greta oto, to see through the secrets of this natural stealth technology. Their work was published in the Journal of Experimental Biology. Although transparent structures in animals are well established, they appear far more often in ...

Queqiao: The bridge between Earth and the far side of the moon

Queqiao: The bridge between Earth and the far side of the moon
2021-06-10
Because of a phenomenon called gravitational locking, the Moon always faces the Earth from the same side. This proved useful in the early lunar landing missions in the 20th century, as there was always a direct line of sight for uninterrupted radiocommunications between Earth ground stations and equipment on the Moon. However, gravitational locking makes exploring the hidden face of the moon--the far side--much more challenging, because signals cannot be sent directly across the Moon towards Earth. Still, in January 2019, China's lunar probe Chang'e-4 marked the first time a spacecraft landed on the far side of the Moon. Both the lander and the lunar rover it carried have been gathering and sending back images and ...

Cell Phone Use While Driving May Be Tied to Other Risky Road Behaviors in Young Adults

2021-06-10
Philadelphia, June 10, 2021 - A new study from researchers at Children's Hospital of Philadelphia (CHOP) and the University of Pennsylvania's Annenberg Public Policy Center found that 18- to 24-year-olds who use cell phones while driving are more likely to engage in other risky driving behaviors associated with "acting-without-thinking," a form of impulsivity. These findings suggest the importance of developing new strategies to prevent risky driving in young adults, especially those with impulsive personalities. The study was recently published in the International Journal of Environmental Research Public Health. Cell phone use while driving has been linked to increased crash and near-crash risk. Despite bans on handheld cell phone use ...

How do plants balance microbial friends and foes?

How do plants balance microbial friends and foes?
2021-06-10
Plants are constantly exposed to microbes: pathogens that cause disease, commensals that cause no harm or benefit, and mutualists that promote plant growth or help fend off pathogens. For example, most land plants can form positive relationships with arbuscular mycorrhizal fungi to improve nutrient uptake. How plants fight off pathogens without also killing beneficial microbes or wasting energy on commensal microbes is a largely unanswered question. In fact, when scientists within the field of Molecular Plant-Microbe Interactions were asked to come up with their Top 10 Unanswered Questions, the #1 question was "How do plants engage with beneficial microorganisms while at the same time restricting ...

Like night and day: Animal studies may not translate to humans without time considerations

Like night and day: Animal studies may not translate to humans without time considerations
2021-06-10
MORGANTOWN, W.Va. -- Imagine being woken up at 3 a.m. to navigate a corn maze, memorize 20 items on a shopping list or pass your driver's test. According to a new analysis out of West Virginia University, that's often what it's like to be a rodent in a biomedical study. Mice and rats, which make up the vast majority of animal models, are nocturnal. Yet a survey of animal studies across eight behavioral neuroscience domains showed that most behavioral testing is conducted during the day, when the rodents would normally be at rest. "There are these dramatic daily fluctuations--in metabolism, in immune function, in learning and ...

Saliva can be more effective than nasopharyngeal swabs for COVID-19 testing

Saliva can be more effective than nasopharyngeal swabs for COVID-19 testing
2021-06-10
Philadelphia, June 10, 2021 - The collection of nasopharyngeal swab (NPS) samples for COVID-19 diagnostic testing poses challenges including exposure risk to healthcare workers and supply chain constraints. Saliva samples are easier to collect but can be mixed with mucus or blood, and some studies have found they produce less accurate results. A team of researchers has found that an innovative protocol that processes saliva samples with a bead mill homogenizer before real-time PCR (RT-PCR) testing results in higher sensitivity compared to NPS samples. Their protocol appears in The Journal of Molecular Diagnostics, published by Elsevier. "Saliva as a sample type for COVID-19 testing ...

Printing flexible wearable electronics for smart device applications

Printing flexible wearable electronics for smart device applications
2021-06-10
WASHINGTON, June 10, 2021 -- The demand for flexible wearable electronics has spiked with the dramatic growth of smart devices that can exchange data with other devices over the internet with embedded sensors, software, and other technologies. Researchers consequently have focused on exploring flexible energy storage devices, such as flexible supercapacitators (FSCs), that are lightweight and safe and easily integrate with other devices. FSCs have high power density and fast charge and discharge rates. Printing electronics, manufacturing electronics devices and systems by using conventional printing techniques, has proved to be an economical, simple, and scalable strategy for fabricating FSCs. Traditional micromanufacturing ...

New family of atomic-thin electride materials discovered

New family of atomic-thin electride materials discovered
2021-06-10
An exploratory investigation into the behavior of materials with desirable electric properties resulted in the discovery of a structural phase of two-dimensional (2D) materials. The new family of materials are electrides, wherein electrons occupy a space usually reserved for atoms or ions instead of orbiting the nucleus of an atom or ion. The stable, low-energy, tunable materials could have potential applications in nanotechnologies. The international research team, led by Hannes Raebiger, associate professor in the Department of Physics at Yokohama National University in Japan, published their results on June 10th as frontispiece in Advanced Functional Materials. Initially, the team ...

Study shows how permafrost releases methane in the warming Arctic

2021-06-10
Researchers from Skoltech have designed and conducted experiments measuring gas permeability under various conditions for ice-containing sediments mimicking permafrost. Their results can be useful both in modeling and testing techniques for gas production from Arctic reservoirs and in tracing methane emission in high latitudes. The paper was published in the journal Energy&Fuels. Permafrost, even though it sounds very stable and permanent, is actually quite diverse: depending on the composition of the frozen ground, pressure, temperature and so on, it can have varying properties, which are extremely important if you want to build something on permafrost, ...

'Roadmaps' of the brain reveal regions vulnerable to Alzheimer's disease

2021-06-10
GRAND RAPIDS, Mich. (JUNE 10, 2021) -- Much like a supply truck crossing the countryside, the misfolded proteins that damage neurons in Alzheimer's disease travel the "roads" of the brain, sometimes stopping and sometimes re-routing to avoid roadblocks, reports a study published in END ...

COVID-19 creates hearing, balance disorders, aggravates tinnitus symptoms

2021-06-10
MELVILLE, N.Y., June 10, 2021 -- The physiological impacts of COVID-19 seem almost limitless. Complications can range from loss of taste to respiratory distress, with many effects lasting for months. Evidence suggests auditory and vestibular effects should be added to the growing list of symptoms. During the 180th Meeting of the Acoustical Society of America, which will be held virtually June 8-10, Colleen Le Prell, from the University of Texas at Dallas, will talk about hearing and balance disorders associated with coronavirus infection and how pandemic-related stress ...

First AI-based tool for predicting genomic subtypes of pancreatic cancer from histology slides

2021-06-10
Paris, France and New York, NY June 10, 2021 - AP-HP Greater Paris University Hospitals, the leading European clinical trial center with the largest amount of healthcare data in France dedicated to research and Owkin, a startup pioneering Federated Learning and AI technologies for medical research and clinical development, announced the recent results of their ongoing strategic collaboration at ASCO 2021. The abstract and poster entitled "Identification of pancreatic adenocarcinoma molecular subtypes on histology slides using deep learning models" demonstrates the first ...

AMP recommends minimum set of pharmacogenetic alleles to guide clinical CYP2D6 genotype testing, pro

2021-06-10
ROCKVILLE, Md. - June 10, 2021 - The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP2D6 assays, promote standardization of testing across different laboratories and improve patient care. The manuscript, "Recommendations for Clinical CYP2D6 Genotyping Allele Selection: A Joint Consensus Recommendation of the Association for Molecular Pathology, College of American Pathologists, Dutch Pharmacogenetics Working Group of the Royal Dutch Pharmacists Association, and European Society for Pharmacogenomics and Personalized Therapy," was released online ahead of publication in The Journal ...

New method to measure milk components has potential to improve dairy sustainability

2021-06-10
Champaign, IL, June 10, 2021 - Present in blood, urine, and milk, the chemical compound urea is the primary form of nitrogen excretion in mammals. Testing for urea levels in dairy cows helps scientists and farmers understand how effectively nitrogen from feed is used in cows' bodies, with important economic implications for farmers in terms of feed costs, physiological effects for cows such as reproductive performance, and environmental impacts from excretion of nitrogen in dairy cow waste. Thus, accuracy in testing dairy cow urea levels is essential. Since the 1990s, mid-infrared testing of milk urea nitrogen (MUN) has been the most efficient and least invasive way to measure nitrogen use by dairy cows in large numbers. In a recent ...
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