AURORA, Colo. (July 31, 2023) – Researchers at the University of Colorado Anschutz Medical Campus have officially identified a central conduit to obesity: fructose. While fructose’s contribution to obesity is well-known, a study published today in Philosophical Transactions aggregates a large amount of work to make a full argument for how fructose drives obesity and diseases such as diabetes and fatty liver disease. “This is an in-depth review on a hypothesis that puts nature at the center of weight ...

In 2016, recognizing that lack of research in female animals was hampering the success of treatments for mood disorders, the National Institutes of Health (NIH) changed its policy for basic research to include sex as a biological variable for basic research, a move that triggered an explosion of research into sex differences. “Building a strong unbiased foundation of literature will help uncover more effective and sex-specific biomarkers for depression onset and target better treatment,” said Georgia Hodes, assistant professor in the School of Neuroscience, part of the Virginia Tech College of Science. Hodes and co-author Dawson Kropp, a Ph.D. ...

Carbon dioxide levels in Earth’s atmosphere — and, consequently, ocean temperatures — are rising. How high and how fast ocean temperatures can rise can be learned from temperature measurements of ancient oceans. At the same time, energy exploration also relies on knowing the thermal history of oil and gas source rocks, which is often difficult to determine. One of the most promising techniques for measuring ancient ocean temperatures and basin thermal histories relies on the co-enrichment of rare heavy oxygen and heavy carbon ...

Losing the ability to see clearly, and losing the ability to think or remember clearly, are two of the most dreaded, and preventable, health issues associated with getting older. Now, a new study lends further weight to the idea that vision problems and dementia are linked.  In a sample of nearly 3,000 older adults who took vision tests and cognitive tests during home visits, the risk of dementia was much higher among those with eyesight problems – including those who weren’t able ...

August 1, 2023, Mountain View, CA – The SETI Institute is proud to announce that Dr. John Rummel will receive the prestigious 2023 Drake Award, recognizing his extraordinary and innovative programmatic contributions and unwavering advocacy for SETI and astrobiology. Rummel’s illustrious career has included roles at NASA Headquarters, where he served as Senior Scientist for Astrobiology, Planetary Protection Officer, Deputy Chief of the Mission from Planet Earth Study Office, and Program Scientist for SETI/High Resolution Microwave Survey. Despite sometimes facing significant opposition, Rummel has been an unwavering supporter of SETI science and funding, working to ...

Chestnut Hill, Mass. (08/01/2023 - Boston College Assistant Professor of Biology Emrah Altindis has received a two-year, $275,000-grant from the Beatson Foundation to explore the role of gut microbes and viruses triggering the autoimmunity of Type 1 diabetes. “Our lab is extremely grateful for the generous funding bestowed upon us by the Beatson Foundation,” Altindis said. “The receipt of this grant has evoked a profound sense of both excitement and gratitude within our team. We recognize the significant impact this funding will have on our research endeavors, particularly in the field of Type 1 Diabetes.” Funding for the project, titled ...

UNIVERSITY PARK, Pa. — A patch of ocean in the North Atlantic is stubbornly cooling while much of the planet warms. This anomaly — dubbed the "cold blob" — has been linked to changes in ocean circulation, but a new study found changes in large-scale atmospheric patterns may play an equally important role, according to an international research team led by Penn State. “People often think the atmosphere has a very short memory, but here we provide evidence that atmospheric circulation change is significant enough to induce some long-term impact on the climate system,” ...

Highlights: Michigan State University researchers are leading a $1.8 million grant project funded by the Office of Naval Research to evolve artificial intelligence. The research would make it possible to use AI more reliably for tasks we already accomplish with help from popular AI tools like ChatGPT. It could also enable people to entrust AI systems with more advanced jobs that rely on understanding language and visual information, including education, navigation and multimodal question-answering systems. The team is working to connect “classical” or symbolic AI with current deep neural networks and create a neuro-symbolic framework. ...

“We have discussed in detail the clinical implications of ER in avoiding overtreatment and undertreatment in DCIS.” BUFFALO, NY- August 1, 2023 – A new editorial paper was published in Oncotarget's Volume 14 on July 20, 2023, entitled, “Multiclonality of ER expression in DCIS – Implications for clinical practice and future research.” Estrogen receptor (ER) expression is not routinely evaluated in ductal carcinoma in situ (DCIS). This may be because the prognostic role of ER in DCIS was unclear until the UK/ ANZ DCIS trial in 2021 showed that lack of ER expression in DCIS was associated with a greater than 3-fold risk of ipsilateral recurrence. This ...

The public funding of science is responsible for many of the biomedical and other scientific breakthroughs on which our lives depend. However, the process through which funding decisions are made, the peer review of grant proposals, has been historically understudied, and current approaches can lead to undesirable outcomes. Writing in Research Integrity and Peer Review, Stephen A. Gallo, then affiliated with the American Institute of Biological Sciences, and Michael Pearce, Carole J. Lee, and Elena A. Erosheva from the University of ...

In the peak heat of summer, beachgoers don’t want their plans thwarted by harmful algal blooms (HABs). But current methods to remove or kill toxin-producing algae and cyanobacteria aren’t efficient or practical for direct applications in waterways. Now, researchers reporting in ACS ES&T Water have coated a floating sponge in a charcoal-like powder, and when paired with an oxidizing agent, the technique destroyed over 85% of algal cells from lake and river water samples. Swaths of electric green and bright orange-red HABs, or the less brilliantly colored cyanobacteria Microcystis aeruginosa, can produce toxins that can sicken humans ...

An evaluation of 17 previously published studies suggests that exposure to lead in the womb or in childhood is associated with an increased risk of engaging in criminal behavior in adulthood—but more evidence is needed to strengthen understanding. Maria Jose Talayero Schettino of the George Washington University, U.S., and colleagues present these findings in the open-access journal PLOS Global Public Health. Lead exposure can cause a variety of health challenges, such as cardiac issues, kidney ...

Biofilms are highly resistant communities of bacteria that pose a major challenge in the treatment of infections. While studying biofilm formation in laboratory conditions has been extensively conducted, understanding their development in the complex environment of the human respiratory tract has remained elusive. A team of researchers led by Alexandre Persat at EPFL have now cracked the problem by successfully developing organoids called AirGels. Organoids are miniature, self-organized 3D tissues grown from stem cells to mimic actual body tissues and organs in the human body. They represent ...

Many of the answers for effectively responding to a pathogen lie in its genome. Understanding the genetic code of a pathogen like Ebola or the virus that causes COVID-19 allows scientists to track its movement, predict future behavior, identify the source of the outbreak and, most importantly, develop effective vaccines and treatments. This technology was critical during the pandemic, and it will be even more so with future outbreaks.  That makes the continued development of genomic sequencing one of the most ...

Scientists at Washington University in St. Louis have developed a breath test that quickly identifies those who are infected with the virus that causes COVID-19. The device requires only one or two breaths and provides results in less than a minute. The study is available online in the journal ACS Sensors. The same group of researchers recently published a paper in the journal Nature Communications about an air monitor they had built to detect airborne SARS-CoV-2 — the virus that causes COVID-19 — within about ...

Researchers from the UvA and North Carolina State University have identified the specific mixture of pheromone chemicals that male moths use during courtship. The findings provide more detail about the complex blend of chemicals that males and females of this group of moths use in fundamental short-range communication. The publication in the scientific journal Current Biology appeared on 1 August. Scent compounds are essential for male moths to entice female conspecifics to mate. Both partners need to find and recognize each other in the dark. This is done by sex pheromones secreted by the female. Then it is up to the male to convince the female ...

Immune checkpoint inhibitor (ICI) therapies used to treat cancer come with the risk of adverse autoimmune responses, including arthritis that can persist for years and require joint replacement surgery. Little is known about the specific cells responsible for these events. Researchers at Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, and collaborators led a study to investigate these immune adverse events and identified a specific type of CD8 T cell that characterizes inflammatory arthritis induced by ICI therapies. Researchers ...

Even vulnerable people, who are at risk of severe Covid-19, achieved good antibody levels after three doses of mRNA vaccine. This is shown by a study from the University of Gothenburg on patients having undergone a bone marrow transplant or with liver disease, including cirrhosis. The aim of the study, which has been published in the journal Infectious Diseases, was to investigate the effects of repeated vaccinations and hybrid immunity against Covid-19 among particularly vulnerable individuals. Hybrid immunity refers to the protection provided by vaccination in combination with SARS-CoV-2 ...

UCSF Medical Center Is Among Nation’s Top Hospitals for 2023-24  U.S. News & World Report ranks UCSF Health adult care among nation’s top 10 hospitals in 7 specialties, Best in the West for neurology/neurosurgery and rheumatology UCSF Medical Center has been named to the Honor Roll of the nation’s top hospitals for adult care in U.S. News & World Report’s 2023-24 Best Hospitals rankings, representing the highest quality of care and safety standards in the country.  The distinction was earned by only 22 medical ...

COLUMBIA, Mo. -- When assessing the skills and competencies or “human capital” of long-term care registered nurses in the United States, studies often focus solely on years of experience and traditional educational backgrounds. However, a new study conducted by a nurse scientist now at University of Missouri found that by incorporating additional criteria, such as ability to speak multiple languages, additional certificates or trainings and licenses to practice in multiple states, immigrant nurses often represent far more human capital than their American-born counterparts. Roy Thompson, a postdoctoral fellow in the MU Sinclair School of Nursing ...

In a new study published on 21 July 2023 by the journal Bone Research, a team of researchers from Johns Hopkins University, using a combination of lineage tracing and single-cell RNA sequencing (scRNA-seq), delved into the contribution of synovial/tendon sheath progenitor cells to heterotopic bone formation. The researchers identified a distinct population of Tppp3+ tendon progenitor cells that actively participated in the formation of ectopic bone in vivo. Their findings provide new insights into the intricate cellular processes driving heterotopic ossification and offer potential therapeutic targets to prevent and ...

It’s easy to imagine that growing up in a neighborhood with safe and clean parks, little to no discrimination, and where people are not struggling financially makes for a lower-stress childhood. In contrast, neighborhoods with few community spaces, violence, and poverty create a higher-stress environment for a child to live in. Unfortunately, systemic and structural issues such as wealth inequality, residential segregation, barriers to home ownership, and environmental injustice in neighborhoods where Black American adolescents disproportionately reside make ...

A type of soil called terra preta da Amazônia, or Amazon dark earth (ADE), promotes faster growth of trees and enhances their development in qualitative terms, according to an article published in the journal Frontiers in Soil Science.  The findings reported in the article resulted from studies supported by FAPESP (projects 20/08927-0, 18/19000-4 and 14/50320-4) under the aegis of its Biodiversity, Characterization, Conservation, Restoration and Sustainable Use Program (BIOTA).  “ADE is rich in nutrients and supports communities of microorganisms that help plants grow, among other things. Native people of the Amazon have ...

Irvine, Calif., Aug. 1, 2023 — When a fragrance wafted through the bedrooms of older adults for two hours every night for six months, memories skyrocketed. Participants in this study by University of California, Irvine neuroscientists reaped a 226% increase in cognitive capacity compared to the control group. The researchers say the finding transforms the long-known tie between smell and memory into an easy, non-invasive technique for strengthening memory and potentially deterring dementia.   The team’s study appears in Frontiers in Neuroscience. ...

Almost half of patients who experienced a stroke in the right cerebral hemisphere later develop a very unusual symptom: they lose the ability to perceive what is happening in the left side of space. As a result, they tend to eat only the right side of their plate, ignore people on their left, and have great difficulty finding their way around. This disorder, known as hemispatial neglect, does not involve basic visual abilities, which remain intact. “These patients see very well. The problem ...