Metastatic breast cancer’s Trojan horse
Lymph nodes are one of the body’s first lines of defense against disease. Immune cells are dispatched from these biological police stations to fight off intruders. But somehow, lymph nodes are also the first stop for most metastatic cancers.
“It’s paradoxical,” Cold Spring Harbor Laboratory (CSHL) Assistant Professor Semir Beyaz says. “The cancer goes right in, but the immune cells aren’t doing anything. It’s important to understand what’s going on because this is how cancer takes the whole body hostage.”
Beyaz joined with collaborators from Massachusetts General Hospital to investigate. They ...











