OVX836 demonstrated positive safety and immunogenicity data across three dose levels A notable signal of protection of 84% was observed against symptomatic influenza infection Lyon, France – July 28, 2023 – Osivax, a biopharmaceutical company developing vaccines to provide broad-spectrum protection against highly mutating infectious viruses, today announced that The Lancet Infectious Diseases published results from the company’s OVX836-003 study under the title, “Immunogenicity, safety and preliminary efficacy evaluation of OVX836, a nucleoprotein-based universal influenza A vaccine candidate: randomised, double-blind placebo-controlled, Phase 2a trial.” ...

A new Cochrane review finds that the use of physical restraints on care home residents can be reduced without increasing the risk of falls, when frontline care staff are empowered by supportive managers. Physical restraints are devices that restrict freedom of movement and are frequently used in residential care homes, such as nursing homes and assisted living facilities. Examples are bed rails or belts that prevent residents from getting out of bed unassisted. These restraints are ethically problematic as they are mostly ...

July 27, 2023 – How many stars would you give your plastic surgeon? An analysis of Yelp reviews identifies a wide range of surgeon-and practice-related factors that influence whether plastic surgery patients leave positive or negative reviews, reports the September issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer. "Our study also identifies some sources ...

Researchers at the FAMU-FSU College of Engineering are improving the safety and performance of electric vehicles through a new design that protects their batteries. Their design uses tubes filled with paraffin wax, which is a type of phase change material, or PCM. These materials are commonly used to store and dissipate heat, making them useful for protecting a battery from overheating. The researchers’ new method uses PCM-filled tubes in another way, exploring their application as protection against ...

An industrial engineering researcher at The University of Texas at Arlington has earned a grant from the Department of Defense to purchase state-of-the-art hybrid additive-subtractive manufacturing equipment. The project will improve manufacturing capabilities at UTA for printing a wide range of metals and alloys. The grant recipient, Emma Yang, is an assistant professor in the Industrial, Manufacturing, and Systems Engineering Department and an expert in additive and sustainable manufacturing. END ...

In an increasingly diverse, multicultural world, adolescents struggle academically in multicultural environments if they don’t receive consistent and positive messages at school, home and among their peers about cultures that are not their own, a University of California, Davis, study suggests. In a survey of more than 700 teens at public schools in the Southwestern United States, researchers found that while these students attended ethnically diverse schools and reported learning about multiple ...

Susan G. Komen®, the world’s leading breast cancer organization, announced the fourth MBC-focused research grant supported through the Komen Metastatic Breast Cancer Collaborative Research Initiative (MBCCRI), a collaboration between Komen, Duke Cancer Institute and the University of North Carolina Lineberger Comprehensive Cancer Center, which pairs researchers from each of the organizations to work together and address significant gaps in our knowledge about MBC to advance patient care and improve patient outcomes.   In 2021, Komen’s MBCCRI awarded $1.5 million for three research projects focused on finding ...

LA JOLLA, CA—Support for early career researchers is about to get a major boost, thanks to a new fellowship fund established by leaders at La Jolla Institute for Immunology (LJI) and Japan-based global pharmaceutical corporation, Kyowa Kirin, Inc. The fellowship fund has been named in honor of LJI Professor Michael Croft, Ph.D., who has worked closely with Kyowa Kirin scientists through the years. The new Michael Croft Fellowship in Immunology Fund recognizes Croft’s commitment to training and mentoring the next generation ...

UT-Battelle, LLC, has appointed Stephen K. Streiffer to be the next director of Oak Ridge National Laboratory (ORNL). He currently serves as interim director at SLAC National Accelerator Laboratory and will join ORNL in October. “Stephen is a proven leader with diverse experience and a commitment to mission-driven research and development,” said Lou Von Thaer, CEO of Battelle and chair of UT-Battelle, which operates ORNL for the U.S. Department of Energy (DOE). “Throughout his career, Stephen has leveraged existing strengths to create new opportunities and partnerships that strengthen our nation’s ability to innovate ...

Researchers at NYU College of Dentistry’s Pain Research Center have developed a gene therapy that treats chronic pain by indirectly regulating a specific sodium ion channel, according to a new study published in the Proceedings of the National Academy of Sciences (PNAS).   The innovative therapy, tested in cells and animals, is made possible by the discovery of the precise region where a regulatory protein binds to the NaV1.7 sodium ion channel to control its activity.   “Our study represents a major step forward in understanding the underlying biology of the NaV1.7 sodium ion channel, which can be harnessed to provide relief from chronic pain,” said Rajesh ...

At first glance, the hexagonal cells build by honey bees and social wasps may seem similar, but they are significantly different. Honey bees build using wax, whereas wasps use paper. Honey bees build their double-sided combs vertically, whereas wasps build single-sided comb horizontally (i.e., the opening of each cell faces downward). Indeed, the hexagonal cells built by these two groups have independent evolutionary origins. Just like sharks and whales have similar body plans due to their watery environment, bees and wasps build hexagonal cells because the shape maximizes strength and storage area, while minimizing building materials. But what happens when perfectly ...

During the COVID-19 pandemic, governments changed rules and procedures related to Medicaid enrollment. These changes decreased many of the burdens eligible people face when signing up for programs and contributed to a 30 percent increase in Medicaid enrollment. However, the end of public health emergency declarations brings an end to these pandemic policies, which many fear could lead to eligible people losing public health insurance simply because they are unable to fulfill administrative requirements such as accurately filling out and submitting forms, renewing their enrollment ...

New research shows the importance of long-term commitment to the MIND diet for reaping the greatest benefit to brain health. “The benefits within the new study’s three-year clinical trial weren’t as impressive as we’ve seen with the MIND diet observational studies in the past, but there were improvements in cognition in the short-term, consistent with the longer-term observational data,” said lead study author Lisa Barnes, PhD, associate director of the Alzheimer’s Disease Research Center at RUSH. Results from the study, published in The New England Journal of Medicine, showed that within a three-year period, there was no significant ...

July 27, 2023 – Race/ethnicity is not an independent predictor of hospital readmission in patients undergoing breast reconstruction surgery, reports a study in the August issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer. Among patients who have unplanned hospitalizations after breast reconstruction, costs are substantially higher for Black or Hispanic patients, according to the new research by ASPS ...

A soil nematode reanimated from Siberian permafrost had laid dormant for approximately 46,000 years, according to a study publishing July 27, 2023 in the open access journal PLOS Genetics by Anastasia Shatilovich at the Institute of Physicochemical and Biological Problems in Soil Science RAS in Russia, Vamshidhar Gade at the Max Planck Institute for Molecular Cell Biology and Genetics in Germany, and colleagues. Some animals, such as tardigrades, rotifers, and nematodes, can survive harsh conditions by entering a dormant state known as “cryptobiosis”. Previously, nematode individuals were reanimated from samples collected from a fossilized burrow in silt deposits ...

For over two hundred years, the origin of the Indo-European languages has been disputed. Two main theories have recently dominated this debate: the ‘Steppe’ hypothesis, which proposes an origin in the Pontic-Caspian Steppe around 6000 years ago, and the ‘Anatolian’ or ‘farming’ hypothesis, suggesting an older origin tied to early agriculture around 9000 years ago. Previous phylogenetic analyses of Indo-European languages have come to conflicting conclusions about the age of the family, due to the combined effects of inaccuracies and inconsistencies in the datasets they used and limitations in the way that phylogenetic methods analyzed ...

Some organisms, such as tardigrades, rotifers, and nematodes, can survive harsh conditions by entering a dormant state known as “cryptobiosis.” In 2018, researchers from the Institute of Physicochemical and Biological Problems in Soil Science RAS in Russia found two roundworms (nematode) species in the Siberian Permafrost. Radiocarbon dating indicated that the nematode individuals have remained in cryptobiosis since the late Pleistocene, about 46,000 years ago. Researchers from the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in ...

PHILADELPHIA – A gene encoding a protein linked to tau production—tripartite motif protein 11 (TRIM11)—was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer’s disease (AD), while improving cognitive and motor abilities, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Additionally, TRIM11 was identified as playing a key role in removing the protein tangles that cause neurodegenerative diseases, like AD. The findings are published today in Science. ...

Cognitive and computer scientists at the University of Toronto, Universitat Pompeu Fabra and the Catalan Institution for Research and Advanced Studies have found child language development and the historical evolution of the world’s languages share a common cognitive foundation—a core knowledge base where patterns of children’s language innovation can predict patterns of language evolution, and vice versa. Published today in Science, the paper is a first-of-its-kind step toward a unified theory of the lexicon and the mind examined across timescales. The result may also help predict how a word’s meaning may change ...

People often debate whether social media creates "echo chambers" by showing users content that matches their politics and in turn increases polarization. A new study published today in the journal Nature reports that reducing Facebook users' exposure to content from politically "like-minded" sources had no measurable effect on their political beliefs or attitudes during the 2020 U.S. presidential election. The findings are part of a broader research project examining the role of ...

Australia’s rich and diverse fauna never fails to surprise us, as a new spider species has been documented from the continent. The novel species, a blind daddy long-legs, was found in boreholes in the arid Pilbara of Western Australia. It is the first cave-adapted daddy long-legs spider reported from the continent, with other blind species of its genus so far only found in Thailand, Laos, and Vietnam. “It represents a subfamily that was previously thought to be restricted to the tropical north and east of the continent,” says Bernhard Huber, one of the authors of a recent study published ...

27 July 2023 Geological Society of America Release No. 23-28 Contact: Justin Samuel +1-303-357-1026 jsamuel@geosociety.org Boulder, Colo., USA: GSA is pleased to welcome three exceptional new Fellows who will join us in our mission to advance geoscience knowledge and discovery through excellent writing, research, and advocacy. GSA’s 2023–2024 Science Communication Fellow is Arianna Soldati. Soldati is an assistant professor of volcanology at North Carolina State University. Her lab group works on a variety of topics, ranging from effusive eruptions to critical minerals. She received her Ph.D. in geological sciences from the University of ...

New Haven, Conn. — In a promising form of immunotherapy known as CAR T-cell (chimeric antigen receptor) therapy, the patient’s T cells are engineered to better recognize and attack antigens on the surface of cancer cells. In treatments currently approved for use in battling lymphoma and leukemia, however, the therapy has a drawback: Amidst the cancer-killing frenzy, many engineered T cells become tainted with the remnants of cancer antigens, which causes them to turn on other T cells. This eventually depletes the body of cancer-fighting cells ...

Digital Science, a technology company serving stakeholders across the research ecosystem, is pleased to announce that the Research Corporation for Science Advancement (RCSA) has chosen Symplectic Grant Tracker from Digital Science’s suite of flagship products to advance its aims of providing catalytic funding for innovative scientific research and the development of academic scientists.  RCSA joins the 50+ foundations, charities and funders worldwide who manage their end-to-end grant lifecycle using Symplectic Grant Tracker. Designed from the outset to meet research funding needs, Grant Tracker includes features to assist applicants, reviewers, committees and ...

PHILADELPHIA (July 27, 2023) – Two decades ago, the Practice Environment Scale of the Nursing Work Index was published to measure the nursing practice environment. Although the instrument's use has resulted in advances in science and quality improvement efforts, its potential may be limited by the availability and quality of translations into different languages. Researchers from the University of Pennsylvania School of Nursing (Penn Nursing) investigated published translations of the instrument and have identified ...