Research funding agencies around the world are testing creative approaches to address urgent needs while laying the foundation for discoveries that will meet the unpredictable demands of the future. According to a new expert panel report from the Council of Canadian Academies (CCA), Canada can bolster its research capacity by reducing administrative burdens, experimenting with funding approaches, and cultivating a robust, resilient, and diverse scientific workforce. "In the past year we have seen the power and promise of transformative research and the ability of researchers and funding organizations to pivot in times of crisis," said Shirley M. Tilghman, PhD, O.C., FRS, Chair of the Expert Panel. "But the pandemic has also exacerbated existing inequalities ...

Almost half of the parents who have children together with a parent with schizophrenia or bipolar disorder, are themselves burdened by psychological issues. This can affect family life and the children. This is shown in the research result from the major Danish psychiatry project iPSYCH. We typically choose a partner who resembles us in relation to social status, education and, to some extent, also income. Research has previously established this. A new study now shows that almost half of the parents who have children with a partner who suffers from schizophrenia or bipolar disorder themselves meet the criteria for a mental disorder. By comparison, this is 18 percent for parents in the control group. The results stem from The Danish High-Risk and Resilience ...

Aging is the biggest risk factor for perturbation of the nervous system, even in the absence of distinct disease or trauma. For yet unknown reasons, the impulse conducting, myelinated projections and synaptic connections between nerve cells are especially vulnerable to aging-related degeneration. These pathological alterations often manifest as cognitive, sensory, and motor decline in older adults and represent a serious socio-economic challenge. Malactivation leads to damage Scientists have long assumed that inflammation plays an important role in this process. Mal- or overactivation of distinct cells belonging to the innate immune system - the microglia - appears to promote damage of nerve fibers and synapses ...

As the digital revolution has now become mainstream, quantum computing and quantum communication are rising in the consciousness of the field. The enhanced measurement technologies enabled by quantum phenomena, and the possibility of scientific progress using new methods, are of particular interest to researchers around the world. Recently two researchers at Tampere University, Assistant Professor Robert Fickler and Doctoral Researcher Markus Hiekkamäki, demonstrated that two-photon interference can be controlled in a near-perfect way using ...

For the first time, international experts in psychology have built a framework to diagnose Compulsive Buying-Shopping Disorder - promising help for people struggling to manage their spending behaviour and mental wellbeing. The new guidelines, published in the Journal of Behavioral Addictions, confirms that excessive buying and shopping can be so serious as to constitute a disorder, giving researchers and clinicians new powers to develop more targeted interventions for this debilitating condition. The international collaboration, led by Professor Mike Kyrios from Flinders University's Órama Institute for Mental ...

SINGAPORE - A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS) and Bioprocessing Technology Institute (BTI), as well as Singapore Eye Research Institute (SERI), have identified a genetic mutation (functionally defective CYP39A1 gene) associated with exfoliation syndrome, the most common cause of glaucoma. The findings could pave the way for future research on the cause of exfoliation syndrome and potential cures. Their research was published in Journal of the American Medical Association (JAMA) on 24 February 2021. Exfoliation syndrome is a systemic ...

Artificial intelligence that enhances remote monitoring of water bodies - highlighting quality shifts due to climate change or pollution - has been developed by researchers at the University of Stirling. A new algorithm - known as the 'meta-learning' method - analyses data directly from satellite sensors, making it easier for coastal zone, environmental and industry managers to monitor issues such as harmful algal blooms (HABs) and possible toxicity in shellfish and finfish. Environmental protection agencies and industry bodies currently monitor the 'trophic state' of water - its biological productivity - as an indicator of ecosystem health. Large clusters of microscopic algae, or phytoplankton, is called eutrophication and can ...

Mangroves and seagrasses grow in many places along the coasts of the world, and these 'blue forests' constitute an important environment for a large number of animals. Here, juvenile fish can hide until they are big enough to take care of themselves; crabs and mussels live on the bottom; and birds come to feed on the plants. However, the plant-covered coastal zones do not only attract animals but also microplastics, a new study shows. - The denser the vegetation, the more plastic is captured, says Professor and expert in coastal ecology, Marianne Holmer, from the University of Southern Denmark. She is concerned about how the accumulated microplastics affect animal and plant life. - We know from other ...

The EU-funded BIO-CRIME project - with support from the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) - conducted a scientific investigation on the topic of illegal small animal trade and the associated risk of pathogen transmission. The study focused on the key areas of "illegal small animal trade" and the level of knowledge and proper behaviours of young people and adolescents with "zoonotic diseases" and the "One Health concept". One Health is an approach that recognises that human health is closely linked to the health of animals and our shared ...

In 2019 the climate movement experienced an unprecedented growth in its mobilization capacity and its political and media impact. The success of the movement is closely linked to the figure of Greta Thunberg and the global impact of her discourse and the "Fridays for Future" movement in hundreds of cities around the world. A study by Silvia Díaz-Pérez, Roger Soler-i-Martí and Mariona Ferrer-Fons, members of the UPF JOVIS research group of the Department of Communication, analyses the activist's speeches and messages on social networks and their legitimization through her personal story, and it also looks into the "Fridays for Future" movement in Barcelona, based on Twitter and Instagram posts. The research was based on a project that has received funding from ...

Cryptocurrencies like Bitcoin are becoming increasingly popular. At first glance, they have many advantages: Transactions are usually anonymous, fast and inexpensive. But sometimes there are problems with them. In certain situations, fraud is possible, users can discover information about other users that should be kept secret, and sometimes delays occur. The research unit "Security and Privacy" at TU Wien (Lukas Aumayr and his supervisor Prof. Matteo Maffei) in collaboration with the IMDEA Software Institute (Prof. Pedro Moreno-Sanchez, previously postdoc at TU Wien) and the Purdue University (Prof. Aniket Kate) analyzed these problems and developed an improved protocol. It has now been published and will be presented this year at ...

Sea turtles in the Cayman Islands are recovering from the brink of local extinction, new research shows. Monitoring from 1998-2019 shows loggerhead and green turtle nest numbers increased dramatically, though hawksbill turtle nest numbers remain low. In the first counts in 1998-99, just 39 sea turtle nests were found in total on the three islands. By 2019, the figure was 675. Captive breeding of green turtles and inactivity of a traditional turtle fishery due to tightening of restrictions in 2008 contributed to this - but populations remain far below historical levels and still face threats including ...

In the field of molecular epidemiology, the worldwide scientific community has been steadily sleuthing to solve the riddle of the early history of SARS-CoV-2. Despite recent efforts by the World Health Organization, no one to date has identified the first case of human transmission, or "patient zero" in the COVID-19 pandemic. Finding the earliest possible case is needed to better understand how the virus may have jumped from its animal host first to infect humans as well as the history of how the SARS-CoV-2 viral genome has mutated over time and spread globally. Since the first SARS-CoV-2 virus infection was detected in December 2019, well over a million genomes of SARS-CoV-2 have been sequenced worldwide, ...

May 04, 2021 - In its latest clinical practice guideline on community-acquired pneumonia the American Thoracic Society's guidelines panel addresses the use of nucleic acid-based testing for non-influenza viral pathogens. The guideline was published online in the May 1 issue of the American Journal of Respiratory and Critical Care Medicine. An explainer video may be viewed here. Community-acquired pneumonia is caused by a wide range of respiratory pathogens, prominently including viruses. However, the only viral pathogen addressed by the 2019 clinical practice guideline was influenza. The panel determined that, given the increasing recognition of non-influenza viral causes ...

DAVIS, CA, May 4, 2021 - In a randomized, controlled study* published online in the journal, Nutrients, researchers found that including mixed tree nuts in a weight management program resulted in significant weight loss and improved satiety. Researchers at UCLA compared 95 overweight/obese men and women (BMI 27.0-35.0 kg/m2) ages 30-68 years who consumed either 1.5 ounces of mixed tree nuts or a pretzel snack. Both snacks provided the same number of calories, as part of a hypocaloric weight loss diet (500 calories less than resting metabolic rate) over 12 weeks. This was followed by an isocaloric weight maintenance program for an additional ...

Cancer of the colon and rectum is one of the deadliest forms of cancer, and has in recent years affected growing numbers of young people. In the largest registry study to date, researchers at Karolinska Institutet in Sweden and Harvard University in the USA demonstrate a possible connection between colorectal polyps in close relatives and the risk of developing colorectal cancer. The study, which is published in the British Medical Journal, is of potential consequence for different countries' screening procedures. Colorectal cancer is the second deadliest form of cancer in the world, according to the World Health ...

Nearly one in five older adults say their mental health has gotten worse since the pandemic began in March 2020, and an equal percentage say their sleep has suffered in that time too. More than one in four say they're more anxious or worried than before the COVID-19 era, according to a new poll of people age 50 to 80. Women, people in their 50s and early 60s, and older adults who have a college degree or higher were more likely than others to report worse mental health than before the pandemic, according to the END ...

DALLAS, May 4, 2021 -- A meta-analysis of 14 air pollution studies from around the world found that exposure to high levels of air pollutants during childhood increases the likelihood of high blood pressure in children and adolescents, and their risk for high blood pressure as adults. The study is published in a special issue on air pollution in the Journal of the American Heart Association, an open access journal of the American Heart Association. Other studies look at: the effects of diesel exhaust on the muscle sympathetic nerve; the impact of pollutants on high blood pressure; rates of hospital readmission for heart failure among those exposed ...

Osaka, Japan --Straight-line constant-speed propagation in free space is a basic characteristic of light. In a recent study published in Communications Physics, researchers from Osaka University discovered the phenomenon of reciprocating propagation of laser pulse intensity in free space. Spatiotemporal couplings have been recently used to produce light with tunable group-velocity, direction, and trajectory in free space. For example, the flying focus (a moving laser pulse intensity in the extended Rayleigh length), where longitudinal chromatism and temporal chirp are combined to control the spectrum-dependent focus-separation ...

Scientists have revealed how an antibiotic of 'last resort' kills bacteria. The findings, from Imperial College London and the University of Texas, may also reveal a potential way to make the antibiotic more powerful. The antibiotic colistin has become a last resort treatment for infections caused by some of the world's nastiest superbugs. However, despite being discovered over 70 years ago, the process by which this antibiotic kills bacteria has, until now, been something of a mystery. Now, researchers have revealed that colistin punches holes in bacteria, causing them to pop like balloons. The work, funded by the Medical Research Council and Wellcome Trust, and published in the journal eLife, also identified a way of making the antibiotic more effective at killing bacteria. Colistin ...

New Edith Cowan University (ECU) research has found that by eating just one cup of nitrate-rich vegetables each day people can significantly reduce their risk of heart disease. The study investigated whether people who regularly ate higher quantities of nitrate-rich vegetables, such as leafy greens and beetroot, had lower blood pressure, and it also examined whether these same people were less likely to be diagnosed with heart disease many years later. Cardiovascular diseases are the number one cause of death globally, taking around 17.9 million lives each year. Researchers examined data from over 50,000 people residing in Denmark taking part in the Danish Diet, ...

In a recent article in Sustainability, scientists from Reykjavik University (RU), the University of Gothenburg, and the Icelandic Meteorological Office describe their finding of microplastic in a remote and pristine area of Vatnajokull glacier in Iceland, Europe's largest ice cap. Microplastics may affect the melting and rheological behaviour of glaciers, thus influencing the future meltwater contribution to the oceans and rising sea levels. This is the first time that the finding of microplastic in the Vatnajökull glacier is described. The group visualised and identified microplastic particles of various sizes and materials by optical microscopy and μ-Raman spectroscopy. The discussion about microplastics has mainly been focused on the contamination ...

Over the coming decades, our economy and society will need to dramatically reduce greenhouse gas emissions as called for in the Paris Agreement. But even a future low-carbon economy will emit some greenhouse gases, such as in the manufacture of cement, steel, in livestock and crop farming, and in the chemical and pharmaceutical industries. To meet climate targets, these emissions need to be offset. Doing so requires "negative emissions" technologies, by means of which CO2 is removed from the atmosphere and permanently stored in underground repositories. Researchers at ETH Zurich have now calculated the potential of one of these technologies for Europe: the combination of energy extraction from biomass with the capture and ...

Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they've been extremely difficult to detect -- until now. Using what they describe as a "chemical nose," UC Riverside chemists are able to "smell" when bits of DNA are folded in unusual ways. Their work designing and demonstrating this system has been published in the journal Nature Chemistry. "If a DNA sequence is folded, it could prevent the transcription of a gene linked to that particular piece of DNA," said study author and UCR chemistry professor Wenwan Zhong. "In other words, this could have a positive effect by silencing a gene with the potential to cause cancer or promote tumors." Conversely, DNA folding ...

Talking about your bad day at work could lead to great solutions. Cold Spring Harbor Laboratory (CSHL) Associate Professor Saket Navlakha and his wife, Dr. Sejal Morjaria, an infectious disease physician at Memorial Sloan Kettering Cancer Center (MSK), found a way to predict COVID-19 severity in cancer patients. The computational tool they developed prevents unnecessary expensive testing and improves patient care. Morjaria says, "Generally, I have good intuition for how patients will progress." However, that intuition failed her when confronted with COVID-19. She says: "When the pandemic ...