A new study highlights the University of Colorado Anschutz Medical Campus as an example of how an academic medical center can turn groundbreaking research into commercial products that improve patient care and public health. The paper, published recently in the Journal of Clinical and Translational Science, focuses on the unique ecosystem at CU Anschutz responsible for these innovations. And it specifically details the campus's collaborative culture and how biomedical research is commercialized. The campus has successfully turned academic research into a variety of products. CU Anschutz, for example, developed two vaccines for shingles, Zostavax and Shingrix, and ...

WASHINGTON, June 29, 2021 -- Biodegradable plastics are supposed to be good for the environment. But because they are specifically made to degrade quickly, they cannot be recycled. In Physics of Fluids, by AIP Publishing, researchers from the University of Canterbury in New Zealand have developed a method to turn biodegradable plastic knives, spoons, and forks into a foam that can be used as insulation in walls or in flotation devices. The investigators placed the cutlery, which was previously thought to be "nonfoamable" plastic, into a chamber filled with carbon dioxide. ...

The death of the dinosaurs 66 million years ago was caused by the impact of a huge asteroid on the Earth. However, palaeontologists have continued to debate whether they were already in decline or not before the impact. In a new study, published today in the journal Nature Communications, an international team of scientists, which includes the University of Bristol, show that they were already in decline for as much as ten million years before the final death blow. Lead author, Fabien Condamine, a CNRS researcher from the Institut des Sciences de l'Evolution de Montpellier (France), said: "We looked at the six most abundant dinosaur families through the whole of the Cretaceous, spanning from 150 to 66 million ...

WASHINGTON, June 29, 2021 -- As wind passes through a turbine, it creates a wake that decreases the downstream average wind velocity. The faster the spin of the turbine blades relative to the wind speed, the greater the impact on the downstream wake profile. For wind farms, it is important to control upstream turbines in an efficient manner so downstream turbines are not adversely affected by upstream wake effects. In the Journal of Renewable and Sustainable Energy, by AIP Publishing, researchers from the University of Illinois at Urbana-Champaign show by designing controllers based on viewing ...

WASHINGTON, June 29, 2021 -- Many meteorites, which are small pieces from asteroids, do not experience high temperatures at any point in their existence. Because of this, these meteorites provide a good record of complex chemistry present when or before our solar system was formed 4.57 billion years ago. For this reason, researchers have examined individual amino acids in meteorites, which come in a rich variety and many of which are not in present-day organisms. In Physics of Fluids, by AIP Publishing, researchers from Harvard University show the existence of a systematic group of amino acid polymers across several members ...

The oldest strain of Yersinia pestis--the bacteria behind the plague that caused the Black Death, which may have killed as much as half of Europe's population in the 1300s--has been found in the remains of a 5,000-year-old hunter-gatherer. A genetic analysis publishing June 29 in the journal Cell Reports reveals that this ancient strain was likely less contagious and not as deadly as its medieval version. "What's most astonishing is that we can push back the appearance of Y. pestis 2,000 years farther than previously published studies suggested," says senior author Ben Krause-Kyora, head of the aDNA Laboratory at the University of Kiel in Germany. ...

Ten million years before the well-known asteroid impact that marked the end of the Mesozoic Era, dinosaurs were already in decline. That is the conclusion of the Franco-Anglo-Canadian team led by CNRS researcher Fabien Condamine from the Institute of Evolutionary Science of Montpellier (CNRS / IRD / University of Montpellier), which studied evolutionary trends during the Cretaceous for six major families of dinosaurs, including those of the tyrannosaurs, triceratops, and hadrosaurs. Using a novel statistical modelling method that limited bias associated with gaps in the fossil record, they demonstrated that, for dinosaurs 76 million years ...

WASHINGTON, June 29, 2021 -- Computer simulations have been used with great success in recent months to visualize the spread of the COVID-19 virus in a variety of situations. In Physics of Fluids, by AIP Publishing, researchers explain how turbulence in the air can create surprising and counterintuitive behavior of exhaled droplets, potentially laden with virus. Investigators from the University of Florida and Lebanese American University carried out detailed computer simulations to test a mathematical theory they developed previously. They found nearly identical exhalations could spread in different ...

WASHINGTON, June 29, 2021 -- As pervasive as they are in everyday uses, like encryption and security, randomly generated digital numbers are seldom truly random. So far, only bulky, relatively slow quantum random number generators (QRNGs) can achieve levels of randomness on par with the basic laws of quantum physics, but researchers are looking to make these devices faster and more portable. In Applied Physics Letters, by AIP Publishing, scientists from China present the fastest real-time QRNG to date to make the devices quicker and more portable. The ...

What The Study Did: This study describes four patients who presented with acute myocarditis after mRNA COVID-19 vaccination. Authors: Raymond J. Kim, M.D., of the Duke Cardiovascular Magnetic Resonance Center in Durham, North Carolina, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamacardio.2021.2828) Editor's Note: The article includes conflict of interest disclosures. Please see the articles for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support. INFORMATION: Media advisory: ...

What The Study Did: Researchers describe myocarditis presenting after COVID-19 mRNA vaccination in 23 patients within the Military Health System. Authors: Jay Montgomery, M.D., of Walter Reed National Military Medical Center in Bethesda, Maryland, and Margaret Ryan, M.D., M.P.H., of the Naval Medical Center San Diego, are the corresponding authors. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamacardio.2021.2833) Editor's Note: The article includes conflict of interest disclosures. Please see the articles for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding ...

This press release is in support of a presentation by Dr Ruth Howie presented online at the 37th Annual Meeting of ESHRE. 29 June 2021: Cancer treatments can cause premature ovarian failure (POI) including in girls who want to become mothers eventually. Ovarian tissue cryopreservation (OTC) provides a future fertility option but is invasive, has risks and evidence indicates that most girls don't develop POI. So, doctors face the dilemma of how to offer OTC appropriately. Now, an assessment tool has been found to help predict correctly which female cancer patients aged under 18 years will develop POI and should therefore be offered OTC. Results from a long-term follow-up study of 423 girls and young women show nearly a quarter (24%; n = 9) of the 37 assessed as high ...

WASHINGTON, June 29, 2021 - For more than 60 years, algae have been studied as a potential feedstock for biofuel production, but the cellulose in their cell wall makes it hard to access the critical molecules inside and convert them to biogas. In the Journal of Renewable and Sustainable Energy, from AIP Publishing, an international research team reports their success in using urea and sodium hydroxide (NaOH, commonly known as lye or caustic soda) as a pretreatment of algae, which breaks down cellulose and more than doubles biogas production under their initial experimental conditions. "We were ...

With advances in medical science driving progress against childhood brain tumors, today three out of four young patients survive at least five years beyond diagnosis. However, the outcomes look grim when malignant cells spread, or metastasize. Such is the case with medulloblastoma, a type of brain cancer that arises in the cerebellum, at the back of the head. Although rare in absolute terms -- about 350 cases emerge each year, 60 percent of them in children -- medulloblastoma is the most common and deadliest form of pediatric brain cancer. Metastasis ...

In a new article in Nature Communications, a research group led by Grigory Genikhovich at the University of Vienna has found that the way the main body axis of sea anemones is patterned by different intensities of β-catenin signaling is similar to that of sea urchins and vertebrates. This suggests that this axial patterning mechanism already existed about 650 million years ago. The positioning of all anatomical structures in an embryo is determined by systems of molecular coordinates, which are called body axes. Different regulatory genes are activated at specific locations along the body axes to drive the development of all body parts in correct places. This process is very ...

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have shown how RNA-binding proteins modulate synaptic responses that mediate the transmission of nerve cell impulses. Cells in the central nervous system possess a high degree of flexibility, which enables them to adapt to fluctuating demands and respond to changing patterns of neuronal activity. This is achieved by modulating the connections between nerve cells, which are mediated by structures called synapses that determine how neighboring neurons respond to stimulation. These adjustments in turn require the intracellular transport of mRNAs. Consequently, the required proteins ...

Earthworms experience constant chemical interactions with bacteria, fungi, plants and small invertebrates across soil ecosystems. Even within their tissues, earthworms harbor symbiotic microbes and small animal parasites that trigger internal metabolic responses such as innate immunity. To reveal the fundamental processes that enable animal-microbe symbioses to form and persist, we have to study their metabolic interactions in situ. By combining novel imaging techniques, a team of researchers around Benedikt Geier from the Max Planck Institute for Marine Microbiology ...

Skoltech researchers and their colleagues from Russia and the UK investigated the safety and efficacy of new chemistry in antisense oligonucleotides used to treat spinal muscular atrophy (SMA), a debilitating genetic disease. Their results may lead to the development of drugs with less toxicity and fewer injections needed thanks to prolonged action. The paper was published in the journal Nucleic Acid Therapeutics. Antisense oligonucleotides are single stranded chemically modified fragments of DNA that target pre-messenger RNA, short bits of genetic information a ribosome reads to make a protein. Depending on how a particular antisense oligonucleotide works, the target mRNA can either be destroyed or undergo subtle changes in how it's spliced, i.e. how exons, the ...

Russian scientists have experimentally proved the existence of a new type of quasiparticle - previously unknown excitations of coupled pairs of photons in qubit chains. This discovery could be a step towards disorder-robust quantum metamaterials. The study was published in Physical Review B. Superconducting qubits are a leading qubit modality today that is currently being pursued by industry and academia for quantum computing applications. However, the performance of quantum computers is largely affected by decoherence that contributes to a qubits extremely short lifespan and causes computational errors. Another ...

Pioneering research has revealed the erosion of ancient sediments found deep beneath Antarctic ice could be a vital and previously unknown source of nutrients and energy for abundant microbial life. The study, led by the University of Bristol and published today in Nature's Communications Earth & Environment journal, sheds new light on the many compounds supporting various microbes which form part of a huge subglacial ecosystem. Lead author Dr Beatriz Gill Olivas, a Post-Doctoral Research Associate at the University of Bristol, said: "Although the study focused on samples obtained from a single ...

During summer 2020, the Yangtze River basin experienced persistent, record-breaking meiyu rainfall. Likewise, the region suffered from severe flooding and water damage as accumulated rainfall broke records dating back to 1954. Regions outside the meiyu rain belt received significant summer rainfall as well, including Beijing, located in northeastern China. Typically, an above average meiyu rainfall season follows a strong El Niño during the previous winter. However, summer 2020 followed a neutral El Niño-Southern Oscillation (ENSO) event. Therefore, scientists are working ...

A stimulating environment keeps the "hippocampus" - which is the brain's memory control center - young, so to speak. Causes of this are molecular mechanisms that affect gene regulation. These current findings from studies in mice provide clues as to why an active, varied life can help preserve mental fitness in old age. Researchers from the DZNE and the Center for Regenerative Therapies Dresden (CRTD) at the Technische Universität Dresden report on this in the journal Nature Communications. Human DNA - and this also applies to mice - contains thousands of genes. However, it is not only the genetic blueprint that is decisive for the function of a cell and whether it is healthy or not, but above all which genes can be switched on or off. ...

FECYT - Spanish Foundation for Science and Technology - presented today at the headquarters of the National Museum of Science and Technology, MUNCYT, IN Alcobendas, the results of the third Social Perception Survey of scientific aspects of the COVID-19 in a debate moderated by Pampa García Molina, Editor-in-Chief of the SINC Agency, in which Raquel Yotti, Director of the Carlos III Health Institute of Madrid, Josep Lobera, Professor of Sociology at the Universidad Autónoma de Madrid (UAM) and scientific director of the Social Perception Survey on the scientific aspects of COVID-19 and ...

Polymers are long, chain-like molecules which are everywhere in biology. DNA and RNA are polymers formed by many consecutive copies of nucleotides coupled together. When being transported within or between cells, these biological polymers must pass through nanometre-sized holes called "nanopores". This process also underlies a rapidly developing method for analysing and sequencing DNA called nanopore sensing. The study, published in the journal END ...

Researchers at the University of Leicester have developed a new method to recycle electric vehicle batteries using a ground-breaking new approach that many will have experienced in the dentist's chair. The Faraday Institution project on the recycling of lithium-ion batteries (ReLiB) led by Professor Andy Abbott at the University of Leicester used a new method, involving ultrasonic waves, to solve a critical challenge: how to separate out valuable materials from electrodes so that the materials can be fully recovered from batteries at the end of their life. Current recycling ...