Tinnitus, the ringing, buzzing or hissing sound of silence, varies from slightly annoying in some to utterly debilitating in others. Up to 15% of adults in the United States have tinnitus, where nearly 40% of sufferers have the condition chronically and actively seek relief. A recent study from researchers at the University of Michigan’s Kresge Hearing Research Institute suggests relief may be possible. Susan Shore, Ph.D., Professor Emerita in Michigan Medicine’s Department of Otolaryngology and U-M’s Departments of Physiology and Biomedical Engineering, led research on how the brain processes bi-sensory ...

“The current study analyzed the correlation between BORIS mutations and the expression of the protein in breast cancer cases.” BUFFALO, NY- June 5, 2023 – A new research paper was published in Oncotarget's Volume 14 on May 26, 2023, entitled, “Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression.” The brother of the regulator of imprinted sites (BORIS), 11 zinc-finger transcription factors, ...

The research, published in the journal Alzheimer’s & Dementia, is further evidence that the menopause transition is a particularly important time for women and their doctors to pay attention to heart health, in turn protecting their brain health. “It is shocking to know that two-thirds of Americans with Alzheimer’s disease are women,” said Meiyuzhen (Chimey) Qi, first author and Ph.D. candidate in epidemiology at Pitt Public Health. “The most common modifiable risk factor for dementia is cardiovascular disease, and, interestingly, a woman’s ...

About The Study: Among patients diagnosed with cancer in California and Georgia between 2013 and 2019, only 6.8% underwent germline genetic testing. Compared with non-Hispanic white patients, rates of testing were lower among Asian, Black, and Hispanic patients.  Authors: Allison W. Kurian, M.D., M.Sc., of Stanford University in Stanford, California, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2023.9526) Editor’s Note: Please see the article for additional information, ...

Glut1 deficiency syndrome is a rare and disabling neurological disease still relatively unknown to the medical community. A mutation in the SLC2A1 gene in affected patients causes the glucose transporter GLUT1 to malfunction. Since this transporter is responsible for the glucose entering glial cells, the brain is deprived of some of the sugar it needs to function correctly, leading to seizures, bouts of abnormal movement, and developmental delays. These symptoms can be improved by managing the metabolic disorder that causes the disease via a high-fat ...

The use of mobile technologies to collect and analyze individuals’ location information has produced massive amounts of consumer location data, giving rise to an elaborate multi-billion-dollar system in which consumers can share personal data in exchange for economic benefits. But privacy risks prevail. In a new study, researchers used machine learning to create and test a framework that quantifies personalized privacy risks; performs personalized data obfuscation; and accommodates a variety of risks, utilities, and acceptable levels of risk-utility tradeoff. The framework ...

Among the most fundamental questions in astronomy is: How did the first stars and galaxies form? NASA’s James Webb Space Telescope is already providing new insights into this question. One of the largest programs in Webb’s first year of science is the JWST Advanced Deep Extragalactic Survey, or JADES, which will devote about 32 days of telescope time to uncover and characterize faint, distant galaxies. While the data is still coming in, JADES already has discovered hundreds of galaxies that existed when the universe was less than 600 million years old. The team also has identified galaxies sparkling with a multitude of young, hot ...

A delicate tracery of dust and bright star clusters threads across this image from the James Webb Space Telescope. The bright tendrils of gas and stars belong to the barred spiral galaxy NGC 5068, whose bright central bar is visible in the upper left of this image – a composite from two of Webb’s instruments. NASA Administrator Bill Nelson revealed the image Friday during an event with students at the Copernicus Science Centre in Warsaw, Poland.   NGC 5068 lies around 20 million light-years from Earth in the constellation Virgo. This image of the central, bright star-forming regions ...

A new ‘digital decision support tool’ enabling the transition towards more diversified and sustainable agricultural systems has been developed by an international team of researchers from Germany, France, and Czech Republic.   The research led by Dr Ioanna Mouratiadou from the Leibniz Centre for Agricultural Landscape Research, and published in Environmental Science and Ecotechnology, presents the ‘Digital Agricultural Knowledge and Information System (DAKIS)’ as a data integration ...

Baltimore, MD—New work led by Carnegie’s Phillip Cleves uses cutting-edge CRISPR/Cas9 genome editing tools to reveal a gene that’s critical to stony corals’ ability to build their reef architectures. It is published in Proceedings of the National Academy of Sciences. Stony corals are marine invertebrates that build large skeletons, which form the basis of reef ecosystems. These biodiversity hotspots are home to about a quarter of known marine species. “Coral reefs have ...

Human influences have the potential to reduce the effectivity of communication in bees adding further stress to struggling colonies, according to new analysis. Scientists at the University of Bristol studying honeybees, bumblebees and stingless bees found that variation in communication strategies are explained by differences in the habitats that bees inhabit and differences in the social lifestyle such colony size and nesting habits. The findings, published today in PNAS, reveal that anthropogenic change, such as habitat conversion, climate change and the use of agrochemicals, are altering the world bees occupy, and it is becoming increasingly clearer that this affects communication ...

·  Regulating cell mechanics stimulates hair growth in mice ·  Next step will be testing if delivering microRNA via nanoparticles grows hair ·  Potential for human hair growth   CHICAGO --- Just as people’s joints can get stiff as they age and make it harder for them to move around, hair follicle stem cells also get stiff, making it harder for them to grow hair, reports a new Northwestern Medicine study.  But if the hair follicle’s stem cells are softened, ...

McKinney, TX., June  5, 2023 - The Cure Mito Foundation, a parent-led organization dedicated to advancing research and treatments for Leigh syndrome, has launched the first-of-its-kind online resource about Leigh syndrome,  the  most common type of pediatric mitochondrial disease.  The free resource, “About Leigh Syndrome” (https://www.aboutleighsyndrome.com), serves as a central place where patients, caregivers and doctors can find information on Leigh syndrome, including its symptoms, diagnosis, treatment options, and more. Translation ...

Risk assessment instruments (RAIs) are widely used to inform high-stakes decision making in the criminal justice system and other areas, such as health care and child welfare. These tools typically assume a relation between predictors and outcomes that does not vary with time. But because societies change, this assumption may not hold in all settings, generating what a new study calls cohort bias—a bias resulting from cohort-wide influences not experienced by past or future cohorts. The study, by researchers ...

An innovative and sustainable chemistry developed at the Department of Energy’s Oak Ridge National Laboratory for capturing carbon dioxide from air has been licensed to Holocene, a Knoxville-based startup focused on designing and building plants that remove carbon dioxide from atmospheric air. “ORNL is tackling climate change by developing numerous technologies that reduce or eliminate emissions,” said Susan Hubbard, ORNL deputy for science and technology. “But with billions ...

Music, mice, and microscopic imaging combine to provide new insight into the effects of environmental chemicals on hearing loss. Researchers at the Beckman Institute for Advanced Science and Technology found that early exposure to an environmental chemical called polychlorinated biphenyls, or PCBs, made it more difficult for mice to recover from sound-related trauma sustained later in life. Their paper appears in the Journal of Neuroscience. PCBs are carcinogenic compounds formerly used in industrial and consumer products. Although they were banned in the United States in 1979 and haven’t seen industrial use in decades, their highly ...

Daniel Lidar, the Viterbi Professor of Engineering at USC and Director of the USC Center for Quantum Information Science & Technology, and first author Dr. Bibek Pokharel, a Research Scientist at IBM Quantum, achieved this quantum speedup advantage in the context of a “bitstring guessing game.”  They managed strings up to 26 bits long, significantly larger than previously possible, by effectively suppressing errors typically seen at this scale. (A bit is a binary number that is either zero or one). Quantum computers promise to solve certain problems with an advantage that increases as the ...

A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University have mapped this. The research team has also identified an enzyme, a marker, that they hope will help predict who is at risk of having a myocardial infarction or a stroke due to a ruptured atherosclerotic plaque.  In atherosclerosis , fat  is accumulated in the artery walls creating atherosclerotic ...

CHAMPAIGN, Ill. — Researchers have detected complex organic molecules in a galaxy more than 12 billion light-years away from Earth – the most distant galaxy in which these molecules are now known to exist. Thanks to the capabilities of the recently launched James Webb Space Telescope and careful analyses from the research team, a new study lends critical insight into the complex chemical interactions that occur in the first galaxies in the early universe. University of Illinois Urbana-Champaign astronomy and physics professor Joaquin Vieira and graduate student Kedar Phadke collaborated with researchers at Texas A&M ...

As the Co-Editors-in-Chief of Zoonoses, Dr. Lynn Soong (University of Texas Medical Branch, TX, USA) and Dr. Xiaoping Dong (Chinese Center for Disease Control & Prevention, Beijing, China) extend a warm welcome to Dr. Fernando Rosado Spilki, new Executive Editor-in-Chief (Vector Biology/Epidemiology) of Zoonoses.   Dr. Spilki is currently a Professor in the Institute of Health Sciences at Feevale University, Novo Hamburgo, Brazil. He received B.S. in Veterinary Medicine (2001), M.S. in Veterinary Sciences/Animal Virology (2004) both from the Universidade Federal do Rio Grande do Sul, and his Ph.D. in Genetics & Molecular ...

Fungi stores a third of carbon from fossil fuel emissions and could be essential to reaching net zero, new study reveals Mycorrhizal fungi are responsible for holding up to 36 per cent of yearly global fossil fuel emissions below ground - more than China emits each year The fungi make up a vast underground network all over the planet underneath grasslands and forests, as well as roads, gardens, and houses on every continent on Earth It is not only crucial to storing carbon and keeping the planet cooler, but are also essential to global biodiversity  Researchers ...

Industrialised nations responsible for excessive levels of carbon dioxide emissions could be liable to pay a total of $170 trillion in compensation or reparations by 2050 to ensure climate change targets are met, say researchers.  This money, which amounts to nearly $6 trillion per year or about 7% of annual global Gross Domestic Product (GDP), would be distributed as compensation to low-emitting countries that must decarbonise their economies far more rapidly than would otherwise be required.  Financial redress for the losses and damages that climate-vulnerable countries face due to the excessive CO2 emissions of others is seen as an increasingly important ...

Kim Kaplan 301-588-5314 Kim.Kaplan@usda.gov   BRIDGEcereal: Self-Teaching Web App Improves Speed, Accuracy of Classifying DNA Variations Among Cereal Varieties PULLMAN, WA, June 5, 2023—Agricultural Research Service and Washington State University scientists have developed an innovative web app called BRIDGEcereal [https://bridgecereal.scinet.usda.gov/] that can quickly and accurately analyze the vast amount of genomic data now available for cereal crops and organize the material into intuitive charts that identify patterns locating genes of interest. With the rapid advancements in ...

About The Study: This survey study found that 28% of youth-serving U.S. mental health facilities offered LGBTQ-specific mental health services in 2020. Although some states had relatively high levels of LGBTQ service availability as a percentage of facilities, many of these states had few facilities available to children per capita. Public mental health facilities were less likely to offer LGBTQ-specific mental health services, a concern given that the cost of care is a barrier to services. The findings suggest a need to expand availability of LGBTQ services ...

New research has revealed being active could lower the risk of type 2 diabetes, even in people with a high genetic risk of developing the medical condition. The University of Sydney-led study found higher levels of total physical activity, especially moderate- to vigorous-intensity physical activity, had a strong association with a lower risk of developing type 2 diabetes. The findings were published in the British Journal of Sports Medicine. The researchers say the study demonstrates higher levels of physical activity should be promoted as a major strategy for type 2 diabetes ...