This year marks the 100th anniversary of the discovery of insulin, a scientific breakthrough that transformed Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, from a terminal disease into a manageable condition. Today, Type 2 diabetes is 24 times more prevalent than Type 1. The rise in rates of obesity and incidence of Type 2 diabetes are related and require new approaches, according to University of Arizona researchers, who believe the liver may hold the key to innovative new treatments. "All current therapeutics for ...

Los Angeles, Calif. - The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, today announced that findings from a sub-study of REPRIEVE (A5332/A5332s, an international clinical trial studying heart disease prevention in people living with HIV) have been published in the Journal of the American Medical Association Network Open (JAMA Network Open). The study found that approximately half of study participants, who were considered by traditional measures to be at low-to-moderate risk of future heart disease, had atherosclerotic plaque in their coronary arteries. While it is well-known that people living with HIV are at ...

(OTTAWA, ON) The University of Ottawa, the University of Montreal and the Assembly of First Nations are pleased to announce the newly published First Nations Food, Nutrition and Environment Study (FNFNES) in the Canadian Journal of Public Health. Mandated by First Nations leadership across Canada through Assembly of First Nations Resolution 30 / 2007 and realized through a unique collaboration with researchers and communities, the First Nations Food, Nutrition and Environment Study is the first national study of its kind. It was led by principal investigators Dr. Laurie Chan, a professor ...

UCLA engineers have demonstrated successful integration of a novel semiconductor material into high-power computer chips to reduce heat on processors and improve their performance. The advance greatly increases energy efficiency in computers and enables heat removal beyond the best thermal-management devices currently available. The research was led by Yongjie Hu, an associate professor of mechanical and aerospace engineering at the UCLA Samueli School of Engineering. Nature Electronics recently published the finding in this article. Computer processors have shrunk down to nanometer scales over the years, with billions of transistors sitting on a single computer chip. While the increased number of transistors helps make computers faster and more powerful, it also generates ...

Scientists and doctors at University College London Great Ormond Street Institute of Child Health (UCL GOS ICH) and Great Ormond Street Hospital (GOSH) have given hope of a gene therapy cure to children with a rare degenerative brain disorder called Dopamine Transporter Deficiency Syndrome (DTDS). The team have recreated and cured the disease using state-of-the-art laboratory and mouse models of the disease and will soon apply for a clinical trial of the therapy. Their breakthrough comes just a decade after the faulty gene causing the disease was first discovered by the lead scientist of this work. The results, published in Science Translational Medicine, are so promising that the UK regulatory agency MHRA has advised ...

Boulder, Colo., USA: Article topics include the Great Unconformity of the Rocky Mountain region; new Ediacara-type fossils; the southern Cascade arc (California, USA); the European Alps and the Late Pleistocene glacial maximum; Permian-Triassic ammonoid mass extinction; permafrost thaw; the southern Rocky Mountains of Colorado (USA); "gargle dynamics"; invisible gold; and alluvial fan deposits in Valles Marineris, Mars. These Geology articles are online at https://geology.geoscienceworld.org/content/early/recent . A new kind of invisible gold in pyrite hosted in deformation-related dislocations Denis Fougerouse; Steven M. Reddy; Mark ...

Natural wood remains a ubiquitous building material because of its high strength-to-density ratio; trees are strong enough to grow hundreds of feet tall but remain light enough to float down a river after being logged. For the past three years, engineers at the University of Pennsylvania's School of Engineering and Applied Science have been developing a type of material they've dubbed "metallic wood." Their material gets its useful properties and name from a key structural feature of its natural counterpart: porosity. As a lattice of nanoscale nickel struts, metallic wood is full of regularly spaced cell-sized pores that radically decrease its density without sacrificing the material's ...

Knowing the weight of a commodity provides an objective way to value goods in the marketplace. But did a self-regulating market even exist in the Bronze Age? And what can weight systems tell us about this? A team of researchers from the University of Göttingen researched this by investigating the dissemination of weight systems throughout Western Eurasia. Their new simulation indicates that the interaction of merchants, even without substantial intervention from governments or institutions, is likely to explain the spread of Bronze Age technology to weigh goods. The results were ...

Keep your checklists handy because the 62nd Supplement to the American Ornithological Society's Check-list of North American Birds, publishing today in Ornithology, includes numerous updates to the classification of the continent's bird species. A few highlights from this year's supplement, detailed below, include species splits for Mew Gull, Barred Owl, and Sedge Wren, among quite a few others; a transfer back to an old genus for Ruby-crowned Kinglet; and a revision of the linear sequence of passerine families. The Check-list, published since 1886, is updated annually by the AOS's North American Classification Committee (NACC), the official authority on the names and ...

RICHLAND, Wash.--Researchers have increased the lifetime of a promising electric vehicle battery to a record level, an important step toward the goal of lighter, less expensive and long-lasting batteries for future electric vehicles. The work is reported June 28 in the journal Nature Energy. Such batteries--the goal of research groups the world over--are seen as an important part of the solution to reduce the effects of climate change, and scientists are exploring a dizzying array of options. One solution on the horizon is a lithium-metal battery for electric vehicles. These ...

(San Antonio, June 29, 2021) - UTSA criminology and criminal justice professors Michael R. Smith and Rob Tillyer working in collaboration with University of Cincinnati Professor Robin Engel examined racial and ethnic disparities in the use of force by the Fairfax County Police Department (FCPD). One of the nation's largest county police departments, the FCPD serves Fairfax County, Va., a major metropolitan county near Washington, D.C. The team presented the results of its 18-month study today to the Public Safety Committee of the Fairfax County Board of Supervisors. ...

The historic 2020 hurricane season, with its record-breaking 30 tropical storms and hurricanes, left in its wake hundreds of deaths in the United States, tens of billions of dollars in damages, and one important question: Is this what the future will look like? While most climate scientists agree that hurricane severity, at least in terms of rainfall, will likely increase as the planet warms, there remains uncertainty about the future frequency of hurricanes. Today's climate models offer a range of possible futures, some predicting an increase in North Atlantic hurricane frequency, others a decrease. These conflicting results beg the question: are these ...

HOUSTON - (June 29, 2021) - When you think about trade and market relationships, you might think about brokers yelling at each other on the floor of a stock exchange on Wall Street. But it seems one of the basic functions of a free market is quietly practiced by fungi. New research from a Rice University economist suggests certain networks of fungi embrace an important economic theory as they engage in trading nutrients for carbon with their host plants. This finding could aid the understanding of carbon storage in soils, an important tool in mitigating climate change. A research paper entitled "Walrasian equilibrium behavior in nature" is available online and will appear in an upcoming edition of Proceedings of the National Academy of Sciences. Ted Loch-Temzelides, ...

Among low-income, uninsured, or publicly insured women ages 25-64 years who were not up to date on cervical cancer screening, 72% perceived financial barriers to screening. The most commonly reported barriers were screening appointment costs (71%) and follow-up/future treatment costs (44%), according to a study published in the peer-reviewed Journal of Women’s Health. Click here to read the article now. Screening is effective at reducing the incidence of and mortality associated with cervical cancer. However, disparities exist in cervical cancer incidence and mortality and in cervical cancer screening based ...

Langerhans cell histiocytosis (LCH) is a rare cancer involving dendritic cells, a type of white blood cell that usually helps defend against infections. The current standard of care for LCH, chemotherapy, cures fewer than half of patients. "Our research team focuses on identifying the causes of LCH so that we can develop better therapies for patients," said Dr. Rikhia Chakraborty, assistant professor of pediatrics - hematology and oncology at Baylor College of Medicine. Most cells in LCH lesions are not abnormal dendritic cells but other invading immune cells, such as T cells, that are recruited to sites of disease. The contribution of T cells and other immune cells to LCH disease is not known. Chakraborty and her team at the Texas Children's Cancer Center Histiocytosis Program characterized ...

Mate choice is important for females, who often invest much more energy in offspring than males. However, being too selective is a bad idea, as they might end up not mating at all. Biologists have wondered for a long time how females optimize their chances. Scientists at the University of Groningen have performed experiments with fruit flies that reveal the explanation: mating induces a behavioural change in female flies that makes them more choosy than when they are virgins. The results were published on 21 June in Nature Ecology and Evolution. The fourteenth-century French philosopher Jean Buridan described a donkey who starved to death because he couldn't choose between two bales of hay. Evolutionary biologists have their own version of this decision-making ...

University of Colorado Boulder researchers have discovered that minuscule, self-propelled particles called "nanoswimmers" can escape from mazes as much as 20 times faster than other, passive particles, paving the way for their use in everything from industrial clean-ups to medication delivery. The findings, published this week in the Proceedings of the National Academy of Sciences, describe how these tiny synthetic nanorobots are incredibly effective at escaping cavities within maze-like environments. These nanoswimmers could one day be used to remediate contaminated ...

Research from the McKelvey School of Engineering at Washington University in St. Louis has found a missing piece in the puzzle of optical quantum computing. Jung-Tsung Shen, associate professor in the Preston M. Green Department of Electrical & Systems Engineering, has developed a deterministic, high-fidelity two-bit quantum logic gate that takes advantage of a new form of light. This new logic gate is orders of magnitude more efficient than the current technology. "In the ideal case, the fidelity can be as high as 97%," Shen said. His research was published in May 2021 in the journal Physical Review A. The potential of quantum computers is bound to the unusual properties of superposition -- the ability of a quantum system to contain many distinct properties, or states, ...

Irvine, Calif., June 29, 2021 - Fireworks are synonymous in the United States with the celebration of Independence Day and other special events, but the colorful displays have caused a growing risk to public safety in recent years, according to a study by environmental health researchers at the University of California, Irvine. Relying on real-time air quality measurements crowdsourced from a network of more than 750 automated sensors distributed throughout California, scientists from UCI's Program in Public Health found that short-term, extremely high-particulate-matter air pollution from the widespread ...

This lobster tale begins a few years ago when the proprietor of a northeastern seafood restaurant publicly asserted that exposing lobsters to a little cannabis prior to cooking produced notable changes in their behavior and a less dramatic scene in the kitchen for all concerned, which was the Maine thing. In a paper published online June 29, 2021 in the journal Pharmacology Biochemistry and Behavior, a team led by researchers at University of California San Diego School of Medicine, report on efforts to answer that burning, boiling and baked question. They obtained live lobsters (Homarus americanus) from a supermarket and exposed the crustaceans to up to 60 minutes of vaporized Δ9-tetrahydrocannabinol (THC) -- the principle psychoactive component of cannabis -- then ...

June 29, 2021 - Nutley, NJ - Scientists from the Hackensack Meridian Center for Discovery and Innovation, working with collaborators from across the globe, uncovered the mechanism of action of a novel anti-tuberculosis drug that they have helped develop. The new findings show how the enzyme inhibitor triaza-coumarin, or TA-C, is metabolized by the TB germs, which makes it effective in inhibiting the disease from within, like in a "Trojan horse" attack, according to the new paper in the journal Proceedings of the National Academy of Sciences. "This is a promising new direction of research," said Thomas Dick, member of the CDI faculty. "We are hoping this work can make a difference in the ongoing fight against TB." "The scientists at the CDI who specialize in ...

For many years, researchers have been focused on developing technologies that can help us fight the imminent climate change crisis. They have one goal in common: finding sustainable energy sources that can replace the environmentally toxic fossil fuels. "Photocatalysts" that drive an artificial process that replicates photosynthesis (in which solar energy is converted to useful materials) are promising in this regard, given that we are able to develop the technology needed for them. Crystalline materials, such as strontium titanate (SrTiO3), which can serve as "photocatalysts" in solar devices, can lead us in the direction. SrTiO3 is attractive owing to various other reasons ...

Basic needs of disaster- and conflict-impacted refugees are often met by humanitarian relief goods and services, and until now little was known about how refugees create economic livelihood beyond immediate relief. A new exploratory case study from Portland State University Associate Professor of Management Theodore Khoury reveals how Syrian refugees in the Za'atari camp reached beyond basic disaster relief support and leveraged social capital to create informal economic systems that helped improve their quality of life. The study, "Towards a theory of informal supply networks: An?exploratory case study of the Za'atari refugee camp," is published in the Journal of Operations Management and co-authored by ...

PHILADELPHIA - The use of e-cigarettes, or vaping, causes serious damage to the lungs. After the novel coronavirus responsible for the respiratory disease COVID-19 emerged last year, there have been ongoing concerns about how vaping might impact risk of infection and severity of symptoms. Some evidence shows an increased risk of COVID-19 among those who vape. Research also shows a higher COVID-19 mortality rate in men compared to women, and men are more likely to vape than women. However, there is no evidence to link these two observations. New research from Jefferson sheds light on this by showing that exposure to e-cigarette vapor increases levels of the coronavirus receptor in the lungs ...

A 50% rise in the level of carbon dioxide (CO2) in the atmosphere could reduce rainfall in the Amazon as much as or even more than substitution of the entire forest by pasture. The rise in CO2 would reduce the amount of water vapor emitted by the forest, leading to a 12% annual drop in the volume of rainfall, while total deforestation would reduce rainfall by 9%. These estimates are presented in a study published in Biogeosciences by scientists affiliated with the National Space Research Institute (INPE), the University of São Paulo (USP) and the University of Campinas (UNICAMP) in Brazil, and with Munich Technical University (TUM) in Germany. “CO2 is a basic input for photosynthesis, so when it increases in the atmosphere, plant physiology ...