May 4, 2021 - From the very beginning of the AIDS epidemic in 1981, nurses have been at the forefront of patient care, advocacy, and research. But even in the age of antiretroviral therapy and pre-exposure prophylaxis, many challenges remain in reducing the impact of HIV and AIDS, according to the special May/June issue of END ...

Relatives of the giant crocodile might have been kings of the waterways during the Cretaceous period, eating anything--including dinosaurs--that got a little too close to the water's edge, but the largest of these apex predators still started off small. Figuring out how these little crocs grew up in a world surrounded by giants is no small task. Now crocs fossils from Texas are shedding light on how these animals changed their diets as they grew, helping them find a place of their own in environments alongside their bigger, badder relatives. According to the study, published by Cambridge University Press, the crocodiless in question are members of the Deltasuchus motherali and lived along the coastline of Texas 96 million years ...

Scientists have shed light on why some people who have a stroke do not also have abnormal heart rhythms, even though their hearts contain similar scar tissue. Their results, published today in eLife, could help identify the best treatments for people who might be at risk of recurrent stroke, new heart disorders, or both. Strokes are often caused by abnormal blood flow resulting from rapid, irregular beating in the upper chamber of the heart. This is also called atrial fibrillation (AFib). But some people have strokes that appear to have been caused by the heart, ...

Aachen, Germany and Hennigsdorf/Berlin, Germany, May 4, 2021 - German University Hospital Uniklinik RWTH Aachen ("Uniklinik RWTH Aachen") and diagnostics company SphingoTec GmbH ("SphingoTec") today announced that the endothelial function biomarker bio-ADM aids in the early risk stratification and management of patients suffering from severe COVID-19, in need for escalated intensive care treatment (1). A team lead by the clinical researchers at Uniklinik RWTH Aachen has shown that high bio-ADM levels indicate the severity of the acute respiratory distress ...

Tokyo, Japan - Researchers at Tokyo University of Agriculture and Technology (TUAT) modeled the dynamic instability--the so-called "power hop"--that can cause uncontrollable bouncing and damage tractors when they plow dry ground. The team found that self-excited oscillations can arise when the tractor pushes against the ground. Plowing a field on a tractor may seem like a serene occupation, but sudden vibrations can grow unexpectedly and threaten to topple you under certain conditions. The problem is that in nonlinear systems with coupled components, as with a mechanical tractor, ...

A synthetic approach that improves absorber layers in perovskite solar cells could help them achieve their full potential and draw closer to the performance of leading gallium arsenide devices. Solar cells that rely on perovskite thin films to capture sunlight are the fastest growing photovoltaic technology. Cheaper and easier to manufacture and incorporate into devices than conventional semiconductors, lead halide perovskites also effectively absorb visible light and display long charge carrier diffusion lengths -- an indicator of their ability to maintain light-induced electrons and holes separation and facilitate charge transport. Performance ...

A new Boston University School of Public Health (BUSPH) study has identified for the first time how the aryl hydrocarbon receptor (AhR), an environmental chemical receptor, drives immunosuppression in oral squamous cell carcinoma (OSCC)--and that its removal from malignant cells can result in tumor rejection. Published in the journal Proceedings of the National Academy of Sciences, the study findings provide new insight into the biology of cancer immunosuppression, and identify a new target for cancer immunotherapy treatment. Immune checkpoint inhibitors (immunotherapy drugs) are some of the most important treatments that have emerged for treating many cancers, including OSCC. Targeting immune checkpoint molecules such as PD-1, ...

Measures to contain the Corona pandemic are the subject of politically charged debate and tend to polarize segments of the population. Those who support the measures motivate their acquaintances to follow the rules, while those who oppose them call for resistance in social media. But how exactly do politicization and social mobilization affect the incidence of infection? Researchers at the Max Planck Institute for Human Development have examined this question using the USA as an example. Their findings were published in Applied Network Science. Limit crowds, keep a safe distance, and wear masks. Such non-pharmaceutical ...

Cancerous tumors thrive on blood, extending their roots deep into the fabric of the tissue of their host. They alter the genetics of surrounding cells and evolve to avoid the protective attacks of immune cells. Now, Penn State researchers have developed a way to study the relationship between solid, difficult-to-treat tumors and the microenvironment they create to support their growth. The method has the potential to act as a testbed for drugs and other anticancer treatments, according to Ibrahim T. Ozbolat, associate professor of engineering science and mechanics and biomedical engineering, who led the research. The details of the approach were published in Advanced Biology. Using ...

Despite human inventiveness and ingenuity, we still lag far behind the elegant and efficient solutions forged by nature over millions of years of evolution. This also applies for buildings, where animals and plants, have developed extremely effective digging methods, for example, that are far more energy-efficient than modern tunnelling machines, and even self-repairing foundations that are unusually resistant to erosion and earthquakes (yep, we're talking about roots here). Researchers from all over the world are therefore seeking inspiration in nature to develop the buildings of the future, and researchers from Aarhus University ...

Honeybees have a complex communication system. Between buzzes and body movements, they can direct hive mates to food sources, signal danger, and prepare for swarming - all indicators of colony health. And now, researchers are listening in. Scientists based in Germany - with collaborators in China and Norway - have developed a way to monitor the electrostatic signals that bees give off. Basically, their wax-covered bodies charge up with electrostatic energy due to friction when flying, similar to how rubbing your hair can make it stand on end. That energy then gets emitted during communications. "We were thrilled by the ...

The majority of top-rated fertility apps collect and even share intimate data without the users' knowledge or permission, a collaborative study by Newcastle University and Umea University has found. Researchers are now calling for a tightening of the categorisation of these apps by platforms to protect women from intimate and deeply personal information being exploited and sold. For hundreds of millions of women fertility tracking applications offer an affordable solution when trying to conceive or manage their pregnancy. But as this technology grows in popularity, experts have revealed that most of the top-rated fertility apps collect and share sensitive ...

T-cell acute lymphoblastic leukemia (T-ALL) is a very aggressive type of blood cancer. It is relatively rare but still draws a lot of attention as it mostly develops in children under the age of 20. The standard treatment for T-ALL involves heavy chemotherapy procedures, which result in favorable outcomes with an overall survival of 75% after 5 years. However, some patients do not respond to this treatment, or they only respond for a short period, after which the disease grows back. These patients therefore need alternative therapies. Researchers from the Faculty of Health and Medical Sciences, University of Copenhagen, have now identified a combination treatment, which could potentially benefit patients ...

University of Bristol research into octopus vision has led to a quick and easy test that helps optometrists identify people who are at greater risk of macular degeneration, the leading cause of incurable sight loss. The basis for this breakthrough was published in the latest issue of the Journal of Experimental Biology and describes new technology developed by lead researcher, Professor Shelby Temple, to measure how well octopus- which are colour-blind - could detect polarized light, an aspect of light that humans can't readily see. Using this novel technology, the research team showed that octopus have the most sensitive polarization vision system of any animal tested to date. Subsequent research ...

When COVID-19 patients began filling up ICUs throughout the country in 2020, health care providers faced difficult decisions. Health care workers had to decide which patients were most likely to recover with care and which were not so resources could be prioritized. But a new paper from the University of Georgia suggests that unconscious biases in the health care system may have influenced how individuals with intellectual disabilities were categorized in emergency triage protocols. The state-level protocols, while crucial for prioritizing care during disasters, frequently ...

(Boston)--If you come from a family where people routinely live well into old age, you will likely have better cognitive function (the ability to clearly think, learn and remember) than peers from families where people die younger. Researchers affiliated with the Long Life Family Study (LLFS) recently broadened that finding in a paper published in END ...

Brain implants are used to treat neurological dysfunction, and their use for enhancing cognitive abilities is a promising field of research. Implants can be used to monitor brain activity or stimulate parts of the brain using electrical pulses. In epilepsy, for example, brain implants can determine where in the brain seizures are happening. Over time, implants trigger a foreign body response, creating inflammation and scar tissue around the implant that reduces their effectiveness. The problem is that traditional implants are much more rigid than brain tissue, which has a softness comparable to pudding. Stress between the implant and ...

A new auroral phenomenon discovered by Finnish researchers a year ago is probably caused by areas of increased oxygen atom density occurring in an atmospheric wave channel. The speculative explanation offered by the researchers gained support from a new study. Observations made by University of Helsinki researchers increased the validity of a speculative mechanism according to which a type of aurora borealis named 'dunes' is born. In the new study, photographs of the phenomenon taken by an international group of hobbyists in Finland, Norway and Scotland were compared to concurrent satellite data. The rare type of aurora borealis was seen in the sky on 20 January 2016 and recorded in photos taken by ...

This overlay shows radio (orange) and infrared images of a giant molecular cloud called W49A, where new stars are being formed. A team of astronomers led by Chris DePree of Agnes Scott College used the National Science Foundation's Karl G. Jansky Very Large Array (VLA) to make new, high-resolution radio images of this cluster of still-forming, massive stars. W49A, 36,000 light-years from Earth, has been studied for many decades, and the new radio images revealed some tantalizing changes that have occurred since an earlier set of VLA observations in 1994 and 1995. The ...

Scientists have developed a new "key-hole surgery" technique to extract metals from the earth - which could revolutionise the future of metal mining A team of international researchers, including Dr Rich Crane from the Camborne School of Mines, University of Exeter, have developed a new method to extract metals, such as copper, from their parent ore body. The research team have provided a proof of concept for the application of an electric field to control the movement of an acid within a low permeability copper-bearing ore deposit to selectively dissolve and recover the metal in situ. This is in contrast to the conventional approach for the mining of such deposits ...

Swansea University scientists have uncovered potentially dangerous chemical pollutants that are released from disposable face masks when submerged in water. The research reveals high levels of pollutants, including lead, antimony, and copper, within the silicon-based and plastic fibres of common disposable face masks. The work is supported by the Institute for Innovative Materials, Processing and Numerical Technologies (IMPACT) and the SPECIFIC Innovation & Knowledge Centre Project lead Dr Sarper Sarp of Swansea University College of Engineering said: "All of us need to keep wearing masks as they are essential in ending the pandemic. But we also urgently need more research and regulation on mask production, so we can reduce any risks to the environment and ...

Pyrosomes, named after the Greek words for 'fire bodies' due their bright bioluminescence, are pelagic tunicates that spend their entire lives swimming in the open ocean. They are made up of many smaller animals, known as zooids, that sit together in a tubular matrix, known as tunic (hence the name pelagic tunicates). Because they live in the open ocean, they generally go unnoticed. In spite of this, increasing research points to their importance in marine environments, as they can form dense blooms that impact food web dynamics and contribute to the movement and transformation of organic carbon. The study conducted with GEOMAR research vessel POSEIDON in 2018 and 2019 in the vicinity of the Cabo Verde Islands, of which the results have now been published ...

Scientists at the Walter Reed Army Institute for Research demonstrated that biomarkers associated with traumatic brain injury were elevated among law enforcement and military personnel, particularly in active duty participants with longer duration of service. Most notably, these elevated biomarker levels were observed in individuals without a diagnosed brain injury or concussion. Some law enforcement and military personnel are regularly exposed to low levels of blast, particularly during training, due to the use of explosive charges and high caliber weapons. Understanding effects from these occupational exposures is a military health care priority to improve ...

FAYETTEVILLE, Ark. - A new map including rover paths of the Schrodinger basin, a geologically important area of the moon, could guide future exploration missions.The map was created by a team of interns at the Lunar and Planetary Institute, including Ellen Czaplinski, a University of Arkansas graduate student researcher at the Arkansas Center for Planetary Sciences and first author of a paper published in The Planetary Science Journal. The researchers identified significant geologic features of the Schrödinger basin, located near the lunar south ...

Researchers at the U.S. Department of Energy's National Renewable Energy Laboratory (NREL) developed a breakthrough in energy-efficient phototransistors. Such devices could eventually help computers process visual information more like the human brain and be used as sensors in things like self-driving vehicles. The structures rely on a new type of semiconductor--metal-halide perovskites--which have proven to be highly efficient at converting sunlight into electrical energy and shown tremendous promise in a range of other technologies. "In general, these perovskite semiconductors are a really unique ...