Preoperative PET cuts unnecessary lung surgeries in half
2014-03-26
Reston, Va. (March 21, 2012) – New quantitative data suggests that 30 percent of the surgeries performed for non-small cell lung cancer patients in a community-wide clinical study were deemed unnecessary. Additionally, positron emission tomography (PET) was found to reduce unnecessary surgeries by 50 percent, according to research published in the March issue of the Journal of Nuclear Medicine.
PET imaging prior to surgery helps stage a patient's disease by providing functional images of tumors throughout the body, especially areas where cancer has spread, otherwise known ...
Health concerns swirl around electronic cigarettes
2014-03-26
With sales of electronic cigarettes, or "e-cigarettes," on the rise and expected to hit $1.5 billion this year, concerns over potential health risks of using the trendy devices are also gaining momentum and political clout. An article in Chemical & Engineering News (C&EN), the weekly magazine of the American Chemical Society, delves into what scientists and regulators are doing about e-cigarettes, which are now being cleverly marketed under more appealing names such as hookah pens and vape pipes.
The battery-powered devices deliver an inhalable vapor, with or without ...
An answer to the perennial question: Is it safe to pee in the pool?
2014-03-26
Sanitary-minded pool-goers who preach "no peeing in the pool," despite ordinary and Olympic swimmers admitting to the practice, now have scientific evidence to back up their concern. Researchers are reporting that when mixed, urine and chlorine can form substances that can cause potential health problems. Their study appears in ACS' journal Environmental Science & Technology.
Jing Li, Ernest Blatchley, III, and colleagues note that adding chlorine to pool water is the most common way to kill disease-causing microbes and prevent swimmers from getting sick. But as people ...
Study shows invasive species in waterways on rise due to climate change
2014-03-26
One of the most serious threats to global biodiversity and the leisure and tourism industries is set to increase with climate change according to new research by Queen's University Belfast.
Researchers at Queen's have found that certain invasive weeds, which have previously been killed off by low winter temperatures, are set to thrive as global temperatures increase.
The team based at Quercus, Northern Ireland's centre for biodiversity and conservation science research, predicts that invasive waterweeds will become more widespread over the next 70 years.
The researchers ...
Paracetamol poisoning treatment guidelines costing NHS millions
2014-03-26
Strict guidelines for treating paracetamol overdoses – introduced 18 months ago – are costing the NHS millions of pounds a year, researchers claim.
The number of patients receiving hospital treatment for paracetamol poisoning in the UK each year has risen by almost 50 per cent since the guidelines were updated by the Medicines and Health Regulatory Authority, a study estimates.
Researchers have assessed the impact of the MHRA decision to revise the guidelines, which was taken following the death of a young girl from a paracetamol overdose.
Patients with a life-threatening ...
Cereal flake size influences calorie intake
2014-03-26
People eat more breakfast cereal, by weight, when flake size is reduced, according to Penn State researchers, who showed that when flakes are reduced by crushing, people pour a smaller volume of cereal into their bowls, but still take a greater amount by weight and calories.
"People have a really hard time judging appropriate portions," said Barbara Rolls, professor of nutritional sciences and Helen A. Guthrie Chair in Nutrition. "On top of that you have these huge variations in volume that are due to the physical characteristics of foods, such as the size of individual ...
Kif15: The acrobatic motor protein that could pave the way for new cancer therapies
2014-03-26
Researchers at Warwick Medical School have shown for the first time how a protein motor, Kif15, uses acrobatic flexibility to navigate within the mitotic spindle. Understanding how it works could prove vital for the development of targeted cancer therapies.
The new study, published in eLife, describes the behaviour of Kif15 for the first time and provides a breakthrough step towards understanding the role it plays in cell division.
Many frontline cancer drugs target microtubules, the molecular cables that are used to build the mitotic spindle - the protein machine that ...
Parental addictions associated with adult children's arthritis
2014-03-26
The adult offspring of parents who were addicted to drugs or alcohol are more likely to have arthritis, according to a new study by University of Toronto researchers.
Investigators examined a group of 13,036 adults and found that 20.4 per cent of respondents had been diagnosed with arthritis by a medical professional. Investigators found that 14.5 per cent of all respondents reported having at least one parent whose drug or alcohol use caused problems while were under the age of 18 and still living at home.
Results indicate that individuals whose parents were addicted ...
Study finds secret to cutting sugary drink use by teens
2014-03-26
COLUMBUS, Ohio – A new study shows that teenagers can be persuaded to cut back on sugary soft drinks – especially with a little help from their friends.
A 30-day challenge encouraging teens to reduce sugar-sweetened drink use lowered their overall consumption substantially and increased by two-thirds the percentage of high-school students who shunned sugary drinks altogether.
The "Sodabriety" challenge, piloted by Ohio State University researchers, was an effort to confront the largest source of added sugar in the U.S. diet: sugar-sweetened soft drinks, sports and energy ...
Scientists track 3D nanoscale changes in rechargeable battery material during operation
2014-03-26
UPTON, NY-Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have made the first 3D observations of how the structure of a lithium-ion battery anode evolves at the nanoscale in a real battery cell as it discharges and recharges. The details of this research, described in a paper published in Angewandte Chemie, could point to new ways to engineer battery materials to increase the capacity and lifetime of rechargeable batteries.
"This work offers a direct way to look inside the electrochemical reaction of batteries at the nanoscale to better understand ...
New clue to autism found inside brain cells
2014-03-26
The problems people with autism have with memory formation, higher-level thinking and social interactions may be partially attributable to the activity of receptors inside brain cells, researchers at Washington University School of Medicine in St. Louis have learned.
Scientists were already aware that the type of receptor in question was a potential contributor to these problems – when located on the surfaces of brain cells. Until now, though, the role of the same type of receptor located inside the cell had gone unrecognized. Such receptors inside cells significantly ...
Counting calories in the fossil record
2014-03-26
Starting about 250 million years ago, at the end of the Permian period, brachiopod groups disappeared in large numbers, along with 90 percent of the planet's species. Today, only a few groups, or genera, of brachiopods remain. "Most people won't be familiar with brachiopods. They're pretty rare in the modern ocean," said Jonathan Payne, a paleobiologist at Stanford University.
Meanwhile, bivalves flourished, diversifying into a staggering variety of shapes and sizes, and spread from marine to freshwater habitats. "After the end-Permian mass extinction, we find far fewer ...
Last drinks: Brain's mechanism knows when to stop
2014-03-26
The study found a 'stop mechanism' that determined brain signals telling the individual to stop drinking water when no longer thirsty, and the brain effects of drinking more water than required.
Researcher Professor Derek Denton from the Faculty of Medicine, Dentistry and Health Sciences at the University of Melbourne said the study provided insight into the human instincts that determine survival behaviour and are also of medical importance.
"Different areas of the brain involved in emotional decision-making were activated when people drank water after becoming ...
Two spine surgeons are 3 times safer than 1
2014-03-26
Seattle, WA—A new team approach has improved safety—reducing rates of major complications by two thirds—for complex spinal reconstructive surgery for spinal deformity in adult Group Health patients at Virginia Mason Hospital & Seattle Medical Center. An article in the March issue of Spine Deformity gives a detailed description of the standardized protocol before, during, and after the surgery, stressing the new approach's three main features:
Two spine surgeons in the operating room
A live preoperative screening conference
Monitoring bleeding during the operation
The ...
ATHENA desktop human 'body' could reduce need for animal drug tests
2014-03-26
Creating surrogate human organs, coupled with insights from highly sensitive mass spectrometry technologies, a new project is on the brink of revolutionizing the way we screen new drugs and toxic agents.
ATHENA, the Advanced Tissue-engineered Human Ectypal Network Analyzer project team, is developing four human organ constructs – liver, heart, lung and kidney – that are based on a significantly miniaturized platform. Each organ component will be about the size of a smartphone screen, and the whole ATHENA "body" of interconnected organs would fit neatly on a desk.
"By ...
Life expectancy gains elude overweight teens
2014-03-26
Washington, DC—Although people live longer today than they did 50 years ago, people who were overweight and obese as teenagers aren't experiencing the same gains as other segments of the population, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
The life expectancy of the average American born in 2011 was 78.7 years, according to the U.S. Centers for Disease Control and Prevention. The average lifespan has increased by more than a decade since 1950, but rising obesity rates threaten to take a toll on ...
Sugary drinks weigh heavily on teenage obesity
2014-03-26
New research shows sugary drinks are the worst offenders in the fight against youth obesity and recommends that B.C. schools fully implement healthy eating guidelines to reduce their consumption.
Data from the 2008 Adolescent Health survey among 11,000 grade seven to 12 students in British Columbia schools indicates sugary drinks like soda increased the odds of obesity more than other foods such as pizza, french fries, chips and candies.
The study, published today in the International Journal of Behavioral Nutrition and Physical Activity, found that students in schools ...
Research: Less invasive technique possible in vulvar cancer treatment
2014-03-26
A team of researchers from Women & Infants Hospital of Rhode Island commanded a national stage to present the results of a study evaluating the use of sentinel lymph node dissection in women with vulvar malignancies, and then follow the patients for complications and recurrence.
The team – Drs. Richard G. Moore, Dario Roque, Carolyn McCourt, Ashley Stuckey, Paul A. DiSIlvestro, James Sung, Margaret Steinhoff, Cornelius Granai III, and Katina Robison – presented their work at the annual meeting of the Society of Gynecologic Oncologists (SGO) in Tampa. The oral presentation ...
Lack of coronin 1 protein causes learning deficits and aggressive behavior
2014-03-26
This news release is available in German.
Organisms must be able to sense signals from the outside and translate these into biochemical cues in order to adequately respond to their environment. This capability is also required to process information that reaches the brain. Within the brain, stimulation of neurons activates genes that are required, for example for learning and memory. In collaboration with an international and interdisciplinary team the research group led by Prof. Jean Pieters from the Biozentrum, University of Basel, has now uncovered the role of ...
Using PET scanning to evaluate therapies of Menkes disease
2014-03-26
Scientists at the RIKEN Center for Life Science Technologies have used PET imaging to visualize the distribution in the body of copper, which is deregulated in Menkes disease, a genetic disorder, using a mouse model. This study lays the groundwork for PET imaging studies on human Menkes disease patients to identify new therapy options.
Menkes disease, though rare, is a fearsome genetic disorder. Most affected babies die within the first few years of life. The disease is caused by an inborn fault in the body's ability to absorb copper. The standard treatment today for ...
Diabetes: Good self-management helps to reduce mortality
2014-03-26
Scientists of the Institute of Health Economics and Health Care Management (IGM) and of the Institute of Epidemiology II (EPI II) at Helmholtz Zentrum München (HMGU), together with colleagues of the German Diabetes Center (DDZ) in Düsseldorf, investigated the association between self-management behavior and mortality in patients with type 2 diabetes. HMGU and the DDZ are partners in the German Center for Diabetes Research (DZD).
High self-management index – low mortality
340 study participants with type 2 diabetes were interviewed with regard to their patient behavior ...
Real-life CSI: What can investigators really tell from gunshot residue?
2014-03-26
The popular TV series "CSI" is fiction, but every day, real-life investigators and forensic scientists collect and analyze evidence to determine what happened at crime scenes. In a study published in the ACS journal Analytical Chemistry, scientists say they have developed a more rapid and accurate method that could allow crime scene investigators to tell what kind of ammunition was shot from a gun based on the residue it left behind.
Igor K. Lednev and Justin Bueno point out that when someone fires a gun, burnt particles from the bullet spray out of the weapon onto a ...
Electroacupuncture at Conception and Governor vessels and hUCB-MSCs for cerebral ischemia
2014-03-26
Mesenchymal stem cell transplantation is a novel means of treating cerebral ischemia/reperfusion, and can promote angiogenesis and neurological functional recovery. Acupuncture at Conception and Governor vessels also has positive effects as a treatment for cerebral ischemia/reperfusion. Therefore, Prof. Haibo Yu and co-workers from Affiliated Shenzhen Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine in China hypothesized that electro-acupuncture at Conception and Governor vessels plus mesenchymal stem cell transplantation may have better therapeutic ...
Beer marinade could reduce levels of potentially harmful substances in grilled meats
2014-03-26
The smells of summer — the sweet fragrance of newly opened flowers, the scent of freshly cut grass and the aroma of meats cooking on the backyard grill — will soon be upon us. Now, researchers are reporting that the very same beer that many people enjoy at backyard barbeques could, when used as a marinade, help reduce the formation of potentially harmful substances in grilled meats. The study appears in ACS' Journal of Agricultural and Food Chemistry.
I.M.P.L.V.O. Ferreira and colleagues explain that past studies have shown an association between consumption of grilled ...
Research produces strong evidence for a new class of antidepressant drugs
2014-03-26
Scientists have shown for the first time that a chemical in the brain called galanin is involved in the risk of developing depression.
And the research, undertaken by a European research team, points to a strong reason to develop drugs that modify galanin functioning as a new class of antidepressant drug.
Galanin is a neuropeptide (a small protein) that was discovered and investigated over 30 years ago by various groups including the Swedish scientist Tomas Hokfelt. He is one of the senior authors of the paper published in the journal PNAS.
Professor Hokfelt and ...
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