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Fixing excess carbon dioxide: biocatalyst-driven carboxylation under mild conditions

Fixing excess carbon dioxide: biocatalyst-driven carboxylation under mild conditions
2024-06-10
Carbon capture and utilization technologies for the conversion of carbon dioxide into carboxylic acids have garnered attention recently, with researchers from Tokyo Tech recently demonstrating a biocatalyzed carboxylation reaction of not only natural substrate, pyruvate, but also unnatural one, 2-ketoglutarate, using Thermoplasma acidophilum NADP+- malic enzyme under mild reaction conditions. The proposed strategy can be tailored for the selective synthesis through carbon dioxide fixation reactions. Removing the excess carbon dioxide (CO2) from the environment is not the end goal of the decarbonization process necessary to ...

Lung cancer screening prolongs lives in real-world study

2024-06-10
Among US veterans diagnosed with lung cancer through the Veterans Health Administration healthcare system, those who underwent screening before diagnosis were more likely to be diagnosed with earlier stage disease and had a higher cure rate than those who had not been screened. The findings come from an observational study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. Lung cancer is the leading cause of cancer deaths worldwide, and most patients are diagnosed at ...

New study reveals links between social anxiety, depression and suicidal thoughts in adolescents

2024-06-10
Peer-reviewed – Observational study - People  Adolescents who experience higher levels of social anxiety symptoms are more likely to report increased suicidal thoughts and other depressive symptoms two years later, according to new research.  The University of East Anglia-led study sheds light on the pressing need for early interventions to address society anxiety in young people.  Lead author Dr Kenny Chiu, Clinical Lecturer in Clinical Psychology at UEA’s Department of Clinical Psychology and Psychological Therapies, said: “Social Anxiety Disorder ...

Disturbed blood flow can damage the vessel wall in cases of aortic dilation

Disturbed blood flow can damage the vessel wall in cases of aortic dilation
2024-06-10
Abnormal blood flow in the aorta is linked to inflammation and breakdown of the vessel wall in conditions where the aorta is dilated. This is shown in a study led by researchers at Linköping University. The findings can contribute to better diagnosis and open up new ways to assess the risk of serious and usually fatal complications, such as rupture of the aorta.  All blood in the body passes through the heart about once a minute. With every heartbeat, blood from the heart is pumped up into the aorta. Dilation can occur in all parts ...

Psychosocial skills can stop relapse in people with eating disorders, says expert

2024-06-10
Health services should teach patients with eating disorders psychosocial skills to help more people recover and avoid relapse, according to an expert. Anorexia, bulimia and other eating issues affect millions of people, and eating disorder specialist Bethany Crowley warns that eating disorders are often misunderstood. She suggests a more integrated approach to treating people is needed, to focus on the whole person rather than just the disordered eating. Quieting negative thoughts, learning to cope with emotional triggers and practicing self-compassion are among nine key skills outlined by the therapist in a new book. An Integrative Approach to Treating Eating ...

The discovery of new turbulence transition in fusion plasmas

The discovery of new turbulence transition in fusion plasmas
2024-06-10
Background Fusion energy is that released when two light nuclei combine to form a single heavier one (nuclear fusion reaction). Fusion energy-based power generation (fusion power plant) uses the energy generated when deuterium and tritium combine to form helium. A nuclear fusion reaction does not produce carbon dioxide. In addition, since it is possible to extract deuterium and tritium from the sea water, fusion energy is regarded as a sustainable energy source, and research into its practical application has been progressing rapidly ...

Glowing dye helps surgeons eradicate prostate cancer

2024-06-10
A glowing marker dye that sticks to prostate cancer cells could help surgeons to remove them in real-time, according to a study funded by Cancer Research UK.   Cancer Research UK-funded scientists, based at the Nuffield Department of Surgical Sciences and the Department of Oncology, University of Oxford, Oxford University Hospitals and Oxford NIHR Biomedical Research Centre used a fluorescent dye attached to a special marker molecule to give medics a “second pair of eyes” during surgery for prostate cancer. Twenty-three men with prostate cancer were injected with the marker dye before undergoing prostate removal surgery. The marker dye found areas of cancerous tissue ...

Study: ALS patients treated by neurologists received better care

2024-06-08
ALS patients received better care if they were treated by a neurologist, a new study published in PLOS One has found. But researchers found that Black, older and socially disadvantaged ALS patients were less likely to see a neurologist, raising concerns about equity in treating the deadly disease. Patients who were treated by neurologists were more likely to receive interventions endorsed by the American Academy of Neurology. “This study highlights the importance of neurologist care for ALS patients and the need to overcome barriers and provide care that is more equitable for ALS patients,” ...

What makes roads safer? New UMD study uses AI to find out

2024-06-07
College Park, Md. – Most people use Google Street View to find their way. Dr. Quynh Nguyen, an epidemiologist and statistician at the University of Maryland School of Public Health, uses it to locate spots where your journey might abruptly end. In a study published June 6 in the British Medical Journal (BMJ) of Injury Prevention, Nguyen identifies uses AI tools to identify key environmental elements impacting car-related collisions as well as cyclist-related and pedestrian-related accidents. “Car crashes are the leading cause of death for young people ...

Accessibility issues in cancer care

2024-06-07
Researchers at the University of Michigan are finding that many patients may be encountering significant barriers to cancer care, even from their first phone call to a clinic.  Patients attempting to access cancer care must go through several different levels of communication, both before their initial appointment with a physician and throughout their treatment.  Making those first calls to learn more about available cancer care services or to schedule an appointment at a clinic is an important step toward beginning their treatment journey.   “Racial and ethnic disparities have been observed in the outpatient visit rates for ...

Research details method to get efficient, environmentally friendly lithium

Research details method to get efficient, environmentally friendly lithium
2024-06-07
As the electric vehicle market booms, the demand for lithium — the mineral required for lithium-ion batteries — has also soared. Global lithium production has more than tripled in the last decade. But current methods of extracting lithium from rock ores or brines are slow and come with high energy demands and environmental costs. They also require sources of lithium which are incredibly concentrated to begin with and are only found in a few countries. Now, researchers at the University of Chicago Pritzker School of Molecular Engineering (PME) have optimized a new method for extracting lithium from more dilute — and widespread — sources of the mineral, including seawater, ...

In new experiment, scientists record Earth’s radio waves from the moon

2024-06-07
On Feb. 22, a lunar lander named Odysseus touched down near the Moon’s South Pole and popped out four antennas to record radio waves around the surface—a moment University of Colorado Boulder astrophysicist Jack Burns hails as the “dawn of radio astronomy from the Moon.” It was a major achievement for the tenacious lander, which was built by the Houston-based company Intuitive Machines and had to overcome a series of technical difficulties to make it to the lunar surface. Burns is co-investigator on the radio experiment that flew aboard Odysseus called Radio wave Observations at the Lunar Surface ...

Restoring our ubiquitination machinery to overcome resistance to cancer therapy

Restoring our ubiquitination machinery to overcome resistance to cancer therapy
2024-06-07
“[...] the identification of ubiquitin-conjugating enzymes like UBE2J1 and the innovative deployment of PROTAC-type androgen receptor degraders are crucial in combating prostate cancer and overcoming therapeutic resistance.” BUFFALO, NY- June 7, 2024 – A new editorial paper was published in Oncoscience (Volume 11) on May 6, 2024, entitled, “Restoring our ubiquitination machinery to overcome resistance in cancer therapy.” In this new editorial, researchers Xiaoling Li and Ping Mu from ...

Sky’s the limit for biofuels

Sky’s the limit for biofuels
2024-06-07
The United States has enough biomass potential to produce 35 billion gallons per year of aviation biofuel by 2050, a new report confirms. Oak Ridge National Laboratory’s John Field provided biomass feedstock production expertise to the report focused on the role of the bioeconomy in U.S. decarbonization strategies, which was produced by the Department of Energy’s DECARB program. The report examined the role of biomass in reducing greenhouse gas emissions across the economy, including opportunities to reach negative emissions. It includes data ...

Nirmatrelvir-ritonavir and symptoms in adults with postacute sequelae of SARS-CoV-2 infection

2024-06-07
About The Study: The results of this randomized clinical trial showed that a 15-day course of nirmatrelvir-ritonavir in a population of patients with postacute sequelae of SARS-CoV-2 infection (PASC) was generally safe but did not demonstrate a significant benefit for improving select PASC symptoms in a mostly vaccinated cohort with protracted symptom duration. Further studies are needed to determine the role of antivirals in the treatment of PASC.  Corresponding Author: To contact the corresponding authors, email Linda N. Geng, M.D., Ph.D. (geng@stanford.edu) and Upinder Singh, M.D. (usingh@stanford.edu). To ...

Stanford Medicine trial:15-day Paxlovid regimen safe but adds no clear long-COVID benefit

2024-06-07
In a clinical trial conducted by Stanford Medicine investigators and their colleagues, a 15-day course of Paxlovid — an antiviral drug combination targeting SARS-CoV-2, the virus that causes COVID-19 — proved safe as an extended-duration treatment but didn’t lessen select symptoms of the syndrome known as long COVID: the persistence, or reappearance, of COVID-related symptoms three months or more after an initial COVID-19 infection. The findings are described in a paper to be published ...

Antioxidant gel preserves islet function after pancreas removal

Antioxidant gel preserves islet function after pancreas removal
2024-06-07
Northwestern University researchers have developed a new antioxidant biomaterial that someday could provide much-needed relief to people living with chronic pancreatitis. The study will be published on June 7 in the journal Science Advances. Before surgeons remove the pancreas from patients with severe, painful chronic pancreatitis, they first harvest insulin-producing tissue clusters, called islets, and transplant them into the vasculature of the liver. The goal of the transplant is to preserve a patient’s ability to control their own blood-glucose levels without insulin injections. Unfortunately, the ...

Tiny new species of great ape lived in Germany 11 million years ago

Tiny new species of great ape lived in Germany 11 million years ago
2024-06-07
Ancient apes in Germany co-existed by partitioning resources in their environment, according to a study published June 7, 2024 in the open-access journal PLOS ONE by Madelaine Böhme of Eberhard Karls University of Tübingen, Germany and David R. Begun, of University of Toronto, Canada and colleagues. The Hammerschmiede fossil site in Bavaria, Germany is best known for exceptional remains of the ancient great ape Danuvius dating to the late Miocene Epoch, 11.6 million years ago. Other experts contest the strength of the evidence to support whether Danuvius is a hominid or whether ...

Cascadia Subduction Zone, one of Earth’s top hazards, comes into sharper focus

Cascadia Subduction Zone, one of Earth’s top hazards, comes into sharper focus
2024-06-07
Off the coasts of southern British Columbia, Washington, Oregon and northern California lies a 600 mile-long strip where the Pacific Ocean floor is slowly diving eastward under North America. This area, called the Cascadia Subduction Zone, hosts a megathrust fault, a place where tectonic plates move against each other in a highly dangerous way. The plates can periodically lock up and build stress over wide areas―eventually to be released when they finally lurch against each other. The result: the world’s greatest earthquakes, shaking both seabed and land, and generating tsunamis 100 feet high or more. Such a fault ...

Unlocking another piece of the Parkinson’s puzzle – scientists reveal workings of vital molecular switch

2024-06-07
Scientists at the University of Dundee have uncovered the inner relay of a molecular switch that protects the brain against the development of Parkinson’s disease.   The research provides new potential strategies to develop drugs that may benefit patients with Parkinson’s.   Parkinson’s is the fastest growing brain disorder in the world, however, there are currently no treatments that can slow or arrest the condition.   Previous research conducted at the University had found a gene called PINK1 is central to protecting brain cells against stress. In patients ...

A protein that enables smell—and stops cell death

A protein that enables smell—and stops cell death
2024-06-07
While smell plays a considerable role in the social interactions of humans—for instance, signaling fear or generating closeness—for ants, it is vitally important. Researchers from New York University and the University of Florida found that a key protein named Orco, essential for the function of olfactory cells, is also critical for the cells’ survival in ants.   Their study showed that mutating the orco gene in Harpegnathos saltator jumping ants dramatically decreased the number of olfactory neurons, suggesting that Orco is necessary for the development and life of these cells. The findings, published in Science Advances, offer insights into the cellular ...

New research finds lake under Mars ice cap unlikely

2024-06-07
ITHACA, N.Y. – Cornell University researchers have provided a simple and comprehensive – if less dramatic – explanation for bright radar reflections initially interpreted as liquid water beneath the ice cap on Mars’ south pole. Their simulations show that small variations in layers of water ice – too subtle for ground-penetrating radar instruments to resolve – can cause constructive interference between radar waves. Such interference can produce reflections whose intensity and variability match observations to date – not only in the area proposed to be liquid water, but across the so-called south ...

Study shows link between photo filter use and muscle dysmorphia among teens, young adults

2024-06-07
Toronto, ON, Canada - A new study conducted by researchers at the University of Toronto has unveiled a significant association between the use of photo filters on social media and increased symptoms of muscle dysmorphia among adolescents and young adults in Canada. This study, which analyzed data from 912 participants from the Canadian Study of Adolescent Health Behaviors, emphasizes the growing concern over the impact of digital image manipulation on body image and mental health. The research reveals that the use of photo filters, commonly found on apps like Snapchat, Instagram, and TikTok, is linked to greater muscle dysmorphia symptomatology, a condition marked ...

Mushroom stump waste could be inexpensive, healthy chicken feed supplement

Mushroom stump waste could be inexpensive, healthy chicken feed supplement
2024-06-07
UNIVERSITY PARK, Pa. — Feed costs for producing broiler chickens accounts for 60% to 70% of total production costs, and stump waste from the production of button mushrooms comprises nearly 30% of total mushroom weight. Marrying the two has the potential to reduce both cost and waste, especially in Pennsylvania, which is a national leader in the production of broiler chickens and button mushrooms. To learn whether the two are compatible, a team of Penn State researchers conducted a new study to determine how supplementing the feed of broilers with mushroom stump waste affected the growth and health of the chickens. In findings ...

Simply looking at the natural world in urban areas can reap benefits

Simply looking at the natural world in urban areas can reap benefits
2024-06-07
New eye-tracking research has shown that simply looking at natural elements during urban walks can offer significant mental health benefits.   The study, by Bangor University and Technion- Israel Institute of Technology, published in the scientific journal People and Nature, involved city-dwellers, and showed how paying visual attention to greenery, rather than human-made structures, can alleviate anxiety and enhance restorative feelings.  The 117 urban residents who took part in the study, were guided on a 45-minute urban walk, while wearing eye-tracking ...
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