A researcher at Moffitt Cancer Center and his international team of colleagues have reported study results on a novel multireceptor-targeted somatostatin analogue called pasireotide (SOM230) manufactured by Novartis Pharma AG. The Phase II, open-label, multicenter study in patients with advanced neuroendocrine tumors (NET) whose symptoms were no longer responsive to octreotide LAR therapy found that the drug was effective and well tolerated in controlling patient symptoms. The study results are reported in a recent issue of Endocrine-Related Cancer, a publication of ...

ALBUQUERQUE, N.M. — Two researchers have reprised in the journal Energy Policy their groundbreaking finding that improvements in lighting — from candles to gas lamps to electric bulbs — historically have led to increased light consumption rather than lower overall energy use by society. In an article in the journal Energy Policy, Sandia researcher Jeff Tsao and Harry Saunders of The Breakthrough Institute in Oakland, Calif., predicted in 2010 that the same phenomenon might apply to light-emitting diodes (LEDs), poised to take over from the Edison light bulb as the ...

Researchers at the University of California, San Diego School of Medicine say neutrophils, an abundant type of white blood cell typically tasked with attacking bacteria and other foreign invaders, also plays an unexpected role in mediating insulin resistance – the central characteristic of type 2 diabetes, which afflicts an estimated 26 million Americans. The findings are published in the August 5, 2012 Advance Online Publication of Nature Medicine. Neutrophils are the first immune cells to respond to tissue inflammation, and can promote chronic inflammation by summoning ...

CAMBRIDGE, Mass. -- It's a longstanding question in biology: How do cells know when to progress through the cell cycle? In simple organisms such as yeast, cells divide once they reach a specific size. However, determining if this holds true for mammalian cells has been difficult, in part because there has been no good way to measure mammalian cell growth over time. Now, a team of MIT and Harvard Medical School (HMS) researchers has precisely measured the growth rates of single cells, allowing them to answer that fundamental question. In the Aug. 5 online edition of ...

Genetic variability revealed in malaria genomes newly sequenced by two multi-national research teams points to new challenges in efforts to eradicate the parasite, but also offers a clearer and more detailed picture of its genetic composition, providing an initial roadmap in the development of pharmaceuticals and vaccines to combat malaria. The research appears in two studies published in the latest issue of the journal Nature Genetics. They focus on Plasmodium vivax (P. vivax), a species of malaria that afflicts humans and the most prevalent human malaria parasite outside ...

SEATTLE – Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients with solid tumors – such as those of the breast, prostate, lung and colon – that have metastasized, or spread, throughout the body. A team of scientists led by Fred Hutchinson Cancer Research Center has discovered a key factor that drives this drug resistance – information that ultimately may be used to improve the effectiveness of therapy and buy precious time for patients with advanced cancer. They describe their findings online Aug. 5 in advance of ...

Researchers have found that a bacterium that emerged centuries ago in Europe has now been spreading globally into countries undergoing rapid development and industrialization. Unlike other diarrheal diseases, this one is unlikely to be resolved by providing access to clean water. As developing countries become more industrialized the numbers of infections with dysentery-causing Shigella flexneri are known to decline, associated with improved health, lifestyle and perhaps most importantly access to clean water, but the incidence of another form of the dysentery-causing bacterium, ...

An international study to understand and predict the likely impact of ocean acidification on shellfish and other marine organisms living in seas from the tropics to the poles is published this week (date) in the journal Global Change Biology. Ocean acidification is occurring because some of the increased carbon dioxide humans are adding to the atmosphere dissolves in the ocean and reacts with water to produce an acid. The results suggest that increased acidity is affecting the size and weight of shells and skeletons, and the trend is widespread across marine species. ...

VIDEO: Stem-cell derived heart muscle cells were genetically labeled with fluorescent calcium to flash when they contract. By correlating this optical signal from the graft cells with an electrocardiogram --... Click here for more information. Researchers have made a major advance in efforts to regenerate damaged hearts. Grafts of human cardiac muscle cells, grown from embryonic stem cells, coupled electrically and contracted synchronously with host muscle following transplantation ...

Plants produce toxins to defend themselves against potential enemies, from herbivorous pests to diseases. Oilseed rape plants produce glucosinolates to serve this purpose. However, due to the content of glucosinolates, farmers can only use limited quantities of the protein-rich rapeseed for pig and chicken feed. Now, a team of researchers from the University of Copenhagen has developed a method to hinder unwanted toxins from entering the edible parts of the plant. The breakthrough was published today in the prominent scientific journal Nature. "We have developed an entirely ...

Leaky pipes are a common problem for the water industry: according to UK regulator, Ofwat, between 20 and 40 per cent of the UK's total water supply can be lost through damaged pipes. Developing more accurate ways of finding leaks would enable water companies to save revenue and reduce their environmental impact. The system invented at Sheffield tests pipes by transmitting a pressure wave along them that sends back a signal if it passes any unexpected features, such as a leak or a crack in the pipe's surface. The pressure wave is generated by a valve fitted to an ordinary ...

Philadelphia, PA, August 6, 2012 – Individuals with mutations in BRCA1 and BRCA2 genes have a significantly higher risk of developing breast and ovarian cancers. Families at risk have been seeking genetic testing and counseling based on their mutation carrier status, but the standard method of direct sequencing is labor-intensive, costly, and it only targets a part of the BRCA1 and BRCA2 genes. A group of Canadian scientists has developed a new sequencing approach to provide a more effective method of BRCA1/2 mutational analysis. Their work is published in the September ...

ITHACA, N.Y. — There is a popular belief that sexual orientation can be revealed by pupil dilation to attractive people, yet until now there was no scientific evidence. For the first time, researchers at Cornell University used a specialized infrared lens to measure pupillary changes to participants watching erotic videos. Pupils were highly telling: they widened most to videos of people who participants found attractive, thereby revealing where they were on the sexual spectrum from heterosexual to homosexual. The findings were published August 3 in the scientific journal ...

Book reading is one of the best-known habit humankind has ever known. With the increasing popularity of online books, e-book reading apps have become a rage among book lovers. The rising accessibility to free e-content has prompted every individual to read more books. According to a research conducted by a famous research center, one in five Americans has read an e-book in the past one year. Keeping this in mind, FreeForAllBooks has launched its unique application that enables its users to download free e-books that are easily available on the famous e-commerce website ...

Albert Einstein said that "imagination is more important than knowledge", and now you can learn how to use imagination to shrink your stomach without surgery. Marc Carlin and UK Hypnotherapist, Sheila Granger, will travel to Long Island, NY to teach Doctors, Therapists, and Hypnotists/Hypnotherapists how to work with the gastric band hypnosis process. Dr. Oz recently highlighted how effective the gastric band hypnosis concept was when 3 members of his audience lost a combined 15 pounds in 1 weeks time after working with their hypnotist. Mr. Carlin and Ms. ...

MailPix.com, (www.mailpix.com), the newest online photo-printing site, announced Peter Tahmin, former vice president at Ritz Camera & Image and co-founder of the Ritz Interactive e-commerce network, was appointed to its Board of Advisors. He brings 15 years of e-commerce experience and a lifetime of imaging industry experience. "I'm thrilled about my new advisory role, and I look forward to helping Lerner and MailPix.com chart a smooth course for growth and success," says Tahmin. "It has the potential to be a truly a unique site - one that will leverage ...

Caring for a loved one with Alzheimer's disease takes its toll on everyone in the family. It's a devastating disease that can also have a huge impact on the lives of Alzheimer's caregivers who often neglect their own needs. They may feel guilty by their impatience or inability to provide the specialized level of care required. Many family caregivers of people living with Alzheimer's in Long Beach turn to homecare agencies that have experience caring for them in the comfort of their own homes. They can count on homecare agencies to relieve the physical, emotional, and financial ...

The Free Publicity Focus Group, a top ranked Internet marketing and publicity firm based in Wilmington NC, has released 'How To Market An Ebook'. The report focuses on how book marketing strategies have been impacted by recent changes in the publishing industry and offers vital information for those hoping to successfully market an ebook in the Internet marketing environment. "The marketing model used for books," stated McCauley, "has changed, and this is especially true for ebooks and related products. New book marketing models (and most traditional models) ...

As the economy improves it is important to remember that trucking plays a pivotal role in the recovery. Nearly every good consumed in the U.S. is put on a truck at some point. As a result, the trucking industry hauled 68.9% of all the tons of freight transported in the United States. The trucking industry was an astounding $40 billion industry daily in 2010, representing 86.9% of the nations freight bill[. Put another way, on average, trucking collected 86.9 cents of every dollar spent on freight transportation. Both the tonnage and revenue figures included for-hire (truckload ...

San Diego Self Storage (SDSS) organizational entity of Smart Self Storage of Solana Beach, sponsored ten children from the Solana Beach Boys and Girls Club to attend the San Diego County Fair. Entrance wristbands were given to children of worthy families who were able to access the interactive exhibits at the fair for educational and inspirational purposes. According to SDSS Advertising Manager Sandra Flores, "We had a tremendous response from our outreach program to the Solana Beach Boys and Girls Club and were able to provide access to the San Diego County Fair ...

Many things have to be prepared if you want a vacation with the way backpacker, especially if you are a novice backpacker. Here are some things to watch for novice backpackers: - Limit the amount of clothing that was taken. Bring clothing that is easy to fold and not take up much space. Keep the clothes can also be used on many occasions. For pants, bring a light and easy to dry, so you can easily wash and does not take long to dry the pants. - Take vitamins and medications required. Drug dizziness, runny nose, fever and motion sickness should go into the default ...

Introducing Rok:Brgr's newest location in the heart of South Miami. The first gourmet burger joint and gastro pub, conveniently located next door to Sunset Place. Its' Chicago-style brick walls, dark wood, and huge outdoor patio complete with built in bars and leather banquets, welcome guest to settle into their black leather banquette for a cocktail and a delicious burger. Rok:Brgr has been able to distinguish themselves among popular eateries, their Burgers go beyond Certified Angus Beef ranging from organic turkey and chicken to ahi tuna and veggie. Merging their ...

Today's weddings are more extravagant, innovative and exciting than ever before. Because of this, you will have insured every aspect of your wedding is going to be flawless, and ensure that every moment will be captured forever in time with spectacular photography. You will definitely want to hire a professional photographer to capture your most precious and poignant memories on your big day, but finding the best photographer can be difficult. For this reason, you will want to visit http://www.weddingphotographyadvices.com to learn more about how to choose the perfect wedding ...

Texas is America's top state for business 2012 according to CNBC. HR and payroll software provider halfpricesoft.com released the new ezTimeSheet software which will help TX small businesses run more productively by simplifying HR tasks. This new version makes it easier for business owners or HR managers to tracking employee attendance, working time, PTO, vacation and sick time. And Texas users can even get the 5-user version for free through online TrialPay offer. ¡°HR Management is important for any business and organization; however employee time and attendance tracking ...

Fairfax, VA will soon be home to America's favorite neighborhood pet store. Pet Supplies Plus, a group of community-oriented, specialty pet retailers offering a wide array of pet food, goods, grooming services and animal expertise, will open its doors to pets and their people counterparts in October 2012. In addition to offering a diverse selection of services and supplies, the Pet Supplies Plus of Fairfax will create approximately 20 new jobs and is currently accepting applications for store managers, staff members and groomers. The new pet retailer, located in a 10,000 ...