PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Community strategy reduced opioid overdose deaths in Pennsylvania counties

Community strategy reduced opioid overdose deaths in Pennsylvania counties
2023-03-06
(Press-News.org) PITTSBURGH, March 6, 2023 — The monthly opioid overdose death (ODD) rate fell by 30% in Pennsylvania counties that implemented a novel community-focused strategy developed by University of Pittsburgh researchers, according to a new study published today in the Journal of Studies on Alcohol and Drugs.

By analyzing counties that did or didn’t implement the Pennsylvania Opioid Overdose Reduction Technical Assistance Center (ORTAC) strategy over time, the researchers estimate that this cost-effective, community-led approach prevented 1,818 opioid-related deaths over two years.

“I passionately believe that communities have to come together and be empowered to take control of their own public health to really make sea change on issues like ODD,” said senior author Janice Pringle, Ph.D., professor of pharmacy and therapeutics and director of the Program Evaluation and Research Unit (PERU) at the Pitt School of Pharmacy. “Our study is one of the first to show that a community approach is how you move the needle on preventing ODD.”

According to Pringle, public health issues such as the opioid crisis are usually tackled through dozens of disconnected initiatives led by organizations or systems that target specific populations. But this kind of approach can lead to certain groups of people falling through the cracks and perpetuating disparities in who is accessing care.

“ORTAC aims to bring efforts together, pool resources and integrate services to reduce opioid-related overdose deaths at a community level,” said Pringle. “If the opioid crisis is a tree, one thousand steak knives is not going to chop it down. We need sixty-seven hands — one for each county in Pennsylvania — on the chainsaw.”

Pringle and her team developed a systematic eight-step framework to build and support community coalitions and help them plan, implement and sustain efforts to decrease opioid supply and demand and reduce the risk of opioid overdose in their counties.

The first step involves gathering leadership from multiple sectors — including first responders, emergency departments, the drug and alcohol system, the mental health system and criminal justice — who have a shared goal of addressing the opioid crisis.

“The idea behind ORTAC is that community members and people on the front lines know what’s best for their community,” said lead author Renee Cloutier, Ph.D., research scientist in the Pitt School of Pharmacy’s Department of Pharmacy and Therapeutics and scientific director of PERU. “The ORTAC team worked to develop and activate community coalitions to clarify the problems in their community, generate plans and act on them.”

After assessing local data to understand overdose deaths and identify their community’s unique needs, coalitions developed and enacted a strategic plan to reduce opioid deaths. Interventions included improving access to treatment programs, educating first responders in leave-behind practices for the opioid-reversing drug naloxone, implementing harm reduction strategies such as syringe service programs and drug disposal services, and developing messaging campaigns aimed at reducing stigma.

To understand the impact of ORTAC, the researchers used data from OverdoseFreePA to analyze ODDs from 2016 to 2019 in 29 counties where ORTAC was implemented and 19 comparison counties. While 67% of ORTAC counties had a reduction in ODD per 100,000 people, just 47% of the comparison counties had a reduction over the same period.

After accounting for factors that could affect opioid deaths, such as county distribution of naloxone beyond ORTAC efforts, illicit drug supply and opioid prescriptions, the researchers found that the ODD rate in ORTAC counties was consistently lower than comparison counties over time, a difference ranging from 1.5 to 3.8 deaths per 100,000 people in the first two years following ORTAC implementation.

“If you fund communities and provide structured support, you can make transformational change beyond what might be possible with a top-down approach,” said Cloutier. “We hope to see more funding targeted toward supporting communities on the ground in this way.”

The researchers calculated that it cost less than $6,000 to prevent each overdose death. For comparison, another analysis estimated the savings associated with avoiding a single ODD at $10.5 million.

“Our strategy had a meaningful impact on reducing ODD and is incredibly cost-effective,” said Pringle. “With more funding and support, we can continue to guide communities to reduce the risk of ODD for everyone because this issue is in all our backyards. The opioid crisis affects us all, and there is so much more work to be done.”

Other authors of the study were Arnie Aldridge, Ph.D., and William Dowd, B.A., both of RTI International; and Glenn Hoffman, B.A., B.S., Kristina L. Boyd, M.S., Erh-Hsuan Wang, Ph.D., Kiandra Foster, M.S., and Karley Snyder, M.S., all of Pitt.

This study was funded by the Pennsylvania Commission on Crime and Delinquency.

##

END

[Attachments] See images for this press release:
Community strategy reduced opioid overdose deaths in Pennsylvania counties Community strategy reduced opioid overdose deaths in Pennsylvania counties 2 Community strategy reduced opioid overdose deaths in Pennsylvania counties 3

ELSE PRESS RELEASES FROM THIS DATE:

A mixture of trees purifies urban air best

A mixture of trees purifies urban air best
2023-03-06
Conifers are generally better than broadleaved trees at purifying air from pollutants. But deciduous tree may be better at capturing particle-bound pollution. A new study led by the University of Gothenburg shows that the best trees for air purification depend on the type of pollutant involved. Trees and other greenery in cities provide many benefits that are important for the well-being of residents. Leaves and needles on trees filter air pollutants and reduce exposure to hazardous substances in the air. But which trees purify the air most effectively? Researchers from the University ...

Potential treatment of autoimmune diseases revealed in new study

Potential treatment of autoimmune diseases revealed in new study
2023-03-06
Scientists in Japan have revealed a chemical compound that could be used for the treatment of various autoimmune diseases like multiple sclerosis and rheumatoid arthritis. These diseases occur when the body’s immune response goes wiry. The immune system, which normally attacks pathogens and infections, instead attacks healthy cells and tissues. For the millions of people who suffer from autoimmune diseases worldwide, the result can be debilitating—rheumatoid arthritis causes excessive joint pain, while multiple sclerosis can disable one’s brain and spinal cord function. “The key to the development of autoimmune ...

Physical activity and tailored support fails to deliver lasting benefits for smokers not ready to quit

2023-03-06
Promoting physical activity and other behavioural support can help people wanting to reduce their smoking to quit in the short-term. However, after nine months, physical activity delivers no noticeable benefits – compared with offering no additional support – in the rates of people stopping smoking, according to the findings of a major national study. The Trial of physical Activity and Reduction of Smoking (TARS) study, led by the University of Plymouth with funding from the National Institute for Health and Care Research, took place across four cities – Plymouth, Nottingham, Oxford and ...

Death rates from lung cancer will fall overall in the EU and UK in 2023, but rise among women in France, Italy and Spain

2023-03-06
A total of 1,261,990 people will die from cancer in 2023 in the EU (EU-27). A further 172,314 people will die from the disease in the UK, according to new research published in the leading cancer journal Annals of Oncology [1] today (Monday).   Researchers led by Carlo La Vecchia (MD), a professor at the University of Milan (Italy), estimate there will be a 6.5% fall in cancer death rates in men and a 3.7% fall in women between 2018 and 2023.   They predict that death rates from the ten most common cancers will continue to fall in most European countries in 2023, although the numbers of people dying will go up ...

As urban populations soar wastewater treatment struggles to find sustainable solutions

As urban populations soar wastewater treatment struggles to find sustainable solutions
2023-03-06
Globally, activated sludge treats the majority of urban wastewaters; yet it is one of the most complex biological processes used. It is a sophisticated microbial process fraught with operational problems leading to occasional failures in achieving required effluent quality standards. With the increasing problem of partially treated and raw sewage entering rivers and estuaries, the pressure on the process to cope with ever increasing volumes of wastewater has never been so great. With increasing volumes of dilute wastewater entering treatment plants the high variability in hydraulic and organic ...

Light-induced acceleration of intracellular delivery

Light-induced acceleration of intracellular delivery
2023-03-06
Cell membranes are barriers that maintain cellular homeostasis, and the intracellular delivery of biologically functional molecules, including peptides, proteins, and nucleic acids to manipulate cellular functions. Conventional intracellular uptake processes require high concentrations of biofunctional molecules with low permeability to pass through the cell membrane. This results in low drug activity because the probability of the biofunctional molecules entering target cells and their organelles is low. In addition, many drugs damage healthy cells as well as the cells that are supposed to target due to poor selectivity, making ...

Physician workforce planning must adjust for aging population, changing practice patterns: New analysis

2023-03-06
Why are Canadians having problems accessing physicians despite historic highs in physician numbers? Factoring in changing demographics and physician work trends can help with physician workforce planning, according to a new analysis in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221239. "[T]he increasing [health care] needs of an aging population have been empirically important since around 2005, while the supply of physician service hours has simultaneously declined in a manner that is largely unrelated to the evolving age–sex composition of the physician workforce," writes Dr. Arthur Sweetman, ...

Pregnant people with schizophrenia have threefold risk of interpersonal violence

2023-03-06
Pregnant and postpartum people with schizophrenia have a more than threefold increase in the risk of an emergency department visit for interpersonal violence, compared with those without schizophrenia, according to a new study in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.220689. Interpersonal violence can include physical, sexual and psychological abuse by a family member, intimate partner, acquaintance or stranger. "Though we found a threefold increased risk for individuals with schizophrenia, we also found that ...

Testing for ApoB protein may be a more accurate marker for heart disease risk than testing for cholesterol alone

Testing for ApoB protein may be a more accurate marker for heart disease risk than testing for cholesterol alone
2023-03-05
Getting tested for levels of HDL (the good) and LDL (the bad) cholesterol is part of the annual physical exam. But emerging research is showing that these standard tests may not be the most accurate way to test for heart disease risk. Instead, emerging data suggest that testing for levels of Apolipoprotein B-100 (ApoB), a protein that carries fat molecules, including LDL cholesterol – the so-called “bad cholesterol” – around the body, may be a more accurate risk predictor of atherosclerotic cardiovascular disease, which occurs ...

Alert banners dramatically increase prescribing rates of life-saving heart failure medication

2023-03-05
An automated system that flags which patients could most benefit from an underused yet life-saving cardiology drug more than doubled new prescriptions, according to a pilot program test by researchers at NYU Grossman School of Medicine. “Our findings suggest that tailored electronic notifications can boost the prescription of life-saving drugs,” said study lead author and cardiologist Amrita Mukhopadhyay, MD, a clinical instructor in the Department of Medicine at NYU Langone Health. “By compiling key information in one place, the system may help providers to spend less time searching through medical records during a visit ...

LAST 30 PRESS RELEASES:

New perspective highlights urgent need for US physician strike regulations

An eye-opening year of extreme weather and climate

Scientists engineer substrates hostile to bacteria but friendly to cells

New tablet shows promise for the control and elimination of intestinal worms

Project to redesign clinical trials for neurologic conditions for underserved populations funded with $2.9M grant to UTHealth Houston

Depression – discovering faster which treatment will work best for which individual

Breakthrough study reveals unexpected cause of winter ozone pollution

nTIDE January 2025 Jobs Report: Encouraging signs in disability employment: A slow but positive trajectory

Generative AI: Uncovering its environmental and social costs

Lower access to air conditioning may increase need for emergency care for wildfire smoke exposure

Dangerous bacterial biofilms have a natural enemy

Food study launched examining bone health of women 60 years and older

CDC awards $1.25M to engineers retooling mine production and safety

Using AI to uncover hospital patients’ long COVID care needs

$1.9M NIH grant will allow researchers to explore how copper kills bacteria

New fossil discovery sheds light on the early evolution of animal nervous systems

A battle of rafts: How molecular dynamics in CAR T cells explain their cancer-killing behavior

Study shows how plant roots access deeper soils in search of water

Study reveals cost differences between Medicare Advantage and traditional Medicare patients in cancer drugs

‘What is that?’ UCalgary scientists explain white patch that appears near northern lights

How many children use Tik Tok against the rules? Most, study finds

Scientists find out why aphasia patients lose the ability to talk about the past and future

Tickling the nerves: Why crime content is popular

Intelligent fight: AI enhances cervical cancer detection

Breakthrough study reveals the secrets behind cordierite’s anomalous thermal expansion

Patient-reported influence of sociopolitical issues on post-Dobbs vasectomy decisions

Radon exposure and gestational diabetes

EMBARGOED UNTIL 1600 GMT, FRIDAY 10 JANUARY 2025: Northumbria space physicist honoured by Royal Astronomical Society

Medicare rules may reduce prescription steering

Red light linked to lowered risk of blood clots

[Press-News.org] Community strategy reduced opioid overdose deaths in Pennsylvania counties