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The first local case of mpox caused by an imported case in the Chinese mainland

2023-09-15
(Press-News.org) https://doi.org/10.1016/j.bsheal.2023.07.003

 

Monkeypox (mpox) is a zoonotic disease caused by the mpox virus (MPXV) that has been primarily limited to Central and West African nations since its discovery. The recent spread of the West African lineage of MPXV in historically unaffected countries has raised concerns for global public health. Despite a significant decrease in global mpox cases, there is still a risk of a global resurgence. This study reports the first local case of mpox caused by an imported case in the Chinese mainland. Polymerase chain reaction (PCR) diagnosed the two cases, and the viral genomes were obtained by next-generation sequencing. Genomic analysis revealed that the two strains shared an identical genome sequence and belonged to the B.1.3 branch of the West African lineage, which is the first local case of mpox caused by an imported case in the Chinese mainland, highlighting the potential threat of mpox in China and the immediate need for adequate surveillance measures.

 

Summary

The first local case of monkeypox (mpox) in the Chinese mainland is reported. Secondary infection was observed in the current case caused by sexual contact in the men who have sex with men (MSM) population. The monkeypox virus (MPXV) of current cases belonged to the B.1.3 branch of the West African lineage.  

Keywords: Mpox, MPXV, Nucleic acid test, NGS

 

 

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Biosafety and Health is sponsored by the Chinese Medical Association, managed by National Institute for Viral

Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC).

For more information, please visit https://www.journals.elsevier.com/biosafety-and-health

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Biosafety and Health is available on ScienceDirect (https://www.sciencedirect.com/journal/biosafety-and-health).

Submissions to Biosafety and Health may be made using Editorial Manager®

(https://www.editorialmanager.com/bsheal/default.aspx).

CiteScore: 4.8

ISSN 2590-0536

 

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Daitao Zhang, Xiao Qi, Fu Li, Yanhui Chu, Ke Wu, Jia Li, Xin Meng, Xiangfeng Dou, Zhenyong Ren, Haoyuan Jin, Shuang Li, Yulan Sun, Yanwei Chen, Renqing Li, Dan Li, Weihong Li, Yang Yang, Yang Pan, Wenjie Tan, Quanyi Wang, The first local case of mpox caused by an imported case in the Chinese mainland, Biosafety and Health, Volume 5, Issue 4, 2023, Pages 187-190, ISSN 2590-0536, https://doi.org/10.1016/j.bsheal.2023.07.003

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[Press-News.org] The first local case of mpox caused by an imported case in the Chinese mainland