Premorbid sociodemographic status and multiple sclerosis outcomes with universal health care

JAMA Network Open

2023-09-26

(Press-News.org) About The Study: In this study of working-age adults with multiple sclerosis (MS), premorbid income, education, and marital status correlated with disability and symptom severity in relapse onset and progressive-onset MS, independent of treatment. These findings suggest that socioeconomic status may reflect both structural and individual determinants of health in MS.

Authors: Anna He, M.B.B.S., of the Karolinska Institute in Stockholm, Sweden is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi: 10.1001/jamanetworkopen.2023.34675)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.34675?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=092623

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

Alcohol use and sustained virologic response to hepatitis C virus direct-acting antiviral therapy

2023-09-26

About The Study: In this study of 69,000 adults with hepatitis C virus (HCV) infection, there was no difference in sustained virologic response across alcohol use categories, even for patients with high-risk consumption or alcohol use disorder, after adjusting for potential confounding variables. These findings suggest that restricting access to direct-acting antiviral therapy on the basis of alcohol use creates an unnecessary barrier for patients and challenges HCV elimination goals. Authors: Emily J. Cartwright, M.D., of the Emory University School of Medicine in Atlanta, ...

Earthworms contribute to 6.5% of global grain production, according to new CSU research  

2023-09-26

Earthworms are important drivers of global food production, contributing to approximately 6.5% of grain yield and 2.3% of legumes produced worldwide each year, according to new work published by Colorado State University scientists in the journal Nature Communications.    These new estimates from a trio of CSU researchers mean earthworms may account for as much as 140 million metric tons of food produced annually — roughly comparative to the amount of cereal grains (rice, wheat, rye, oats, barley, maize and millet) ...

Invertebrate decline reduces natural pest control and decomposition of organic matter

2023-09-26

Leipzig. The decline in invertebrates also affects the functioning of ecosystems, including two critical ecosystem services: aboveground pest control and belowground decomposition of organic material, according to a new study published in Current Biology and led by researchers at the German Centre for Integrative Biodiversity Research (iDiv) and Leipzig University. The study provides evidence that loss of invertebrates leads to a reduction in important ecosystem services and to the decoupling of ecosystem processes, making immediate protection measures necessary. Invertebrates, such as insects and also ...

Genetically engineering associations between plants and nitrogen-fixing microbes could lessen dependence on synthetic fertilizer

2023-09-26

Nitrogen is an essential nutrient for plant growth, but the overuse of synthetic nitrogen fertilizers in agriculture is not sustainable. In a review article publishing in the journal Trends in Microbiology on September 26, a team of bacteriologists and plant scientists discuss the possibility of using genetic engineering to facilitate mutualistic relationships between plants and nitrogen-fixing microbes called “diazotrophs.” These engineered associations would help crops acquire nitrogen from the air by mimicking the mutualisms between legumes and nitrogen-fixing bacteria. “Engineering associative diazotrophs to provide nitrogen ...

Impact of parental relatedness on type 2 diabetes and other common diseases uncovered

2023-09-26

A new study finds that consanguinity – unions between close relatives - may increase the risk of common diseases such as type 2 diabetes and post-traumatic stress disorder (PTSD). Researchers from the Wellcome Sanger Institute and their collaborators at Queen Mary University of London analysed the genomic data of diverse groups to investigate the relationship between autozygosity - a measure of genetic relatedness between an individual’s parents - and the prevalence of common diseases, with a novel method that reduces confounding due to sociocultural factors. They focused ...

Redefining global health security: A novel framework sheds light on equity and decolonial approaches

2023-09-26

Redefining Global Health Security: A Novel Framework Sheds Light on Equity and Decolonial Approaches Kuala Lumpur, Malaysia and London, UK – 25 September 2023 In the wake of the COVID-19 pandemic, a new policy paper titled "Global Health Security and the Health-Security Nexus: Principles, Politics and Praxis" in the journal BMJ Global Health, warns of dangers and potential pitfalls associated with the increased attention paid to ‘global health security’ and the growing interaction between public health and security actors. According to the authors, the prevailing ...

Inbreeding can be beneficial in the long run

2023-09-26

"Of all the subspecies of reindeer found in the high north, the Svalbard reindeer has the most inbreeding and the lowest genetic diversity," says Nicolas Dussex, a postdoc at Norwegian University of Science and Technology´s (NTNU) Department of Natural History. It was only 7000-8000 years ago that the first reindeer migrated to Svalbard, most likely from Russia via Novaya Zemlya and the islands of Franz Josef Land. Perhaps there were no more than a few animals that established themselves on the arctic ...

Feds fund research that could slash US cancer deaths by 50%

2023-09-26

HOUSTON – (Sept. 26, 2023) – The Advanced Research Projects Agency for Health (ARPA-H) has awarded $45 million to rapidly develop sense-and-respond implant technology that could slash U.S. cancer-related deaths by more than 50%. The award to a Rice University-led team of researchers from seven states will fast-track development and testing of a new approach to cancer treatment that aims to dramatically improve immunotherapy outcomes for patients with ovarian, pancreatic and other difficult-to-treat cancers. “Instead of tethering patients to hospital beds, IV bags and external monitors, ...

Thiol ligands modify metal nanocluster structures and optical properties

2023-09-26

Metal nanoclusters are tiny, crystalline structures up to two nanometers (2 x 10-9 meters) in diameter that contain a few to hundreds of metal atoms. Understanding the precise assembly of metal nanoclusters is paramount to determining how different structures affect the properties and molecular interactions of these materials. Researchers recently synthesized two similar gold-silver (Au9Ag6) nanoclusters in a highly controlled manner to determine the precise atomic structure of each nanocluster and the effects of specific thiol ligands, or sulfur-containing binding molecules, on material synthesis. Given their extremely small size, metal nanoclusters have ...

Researchers build and test a framework for achieving climate resilience across diverse fisheries

2023-09-26

(Santa Barbara, Calif.) — What makes for a successful climate-resilient fishery, one that sustainably produces resources for human benefit despite increasing climate stressors and human impacts? It’s a question that faces present and future fisheries, their practitioners and fishing communities as the world turns to the ocean to feed its growing population. “For a fishery to be resilient it needs to be able to prepare for, resist, cope with, recover from, or adapt to any given impact,” said Jacob Eurich, who is a research associate at UC Santa Barbara’s Marine Science Institute, and a fisheries scientist at the Environmental Defense Fund (EDF). “In ...

First evidence of olaparib maintenance therapy in patients with newly diagnosed homologous recombination deficient positive/BRCA wild-type ovarian cancer: real-world multicenter study

Premorbid sociodemographic status and multiple sclerosis outcomes with universal health care

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: